IL276290A - Heteroaryl compounds, their pharmaceutical preparations and their medical use - Google Patents
Heteroaryl compounds, their pharmaceutical preparations and their medical useInfo
- Publication number
- IL276290A IL276290A IL276290A IL27629020A IL276290A IL 276290 A IL276290 A IL 276290A IL 276290 A IL276290 A IL 276290A IL 27629020 A IL27629020 A IL 27629020A IL 276290 A IL276290 A IL 276290A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- therapeutic use
- heteroaryl compounds
- heteroaryl
- compounds
- Prior art date
Links
- 125000001072 heteroaryl group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862627921P | 2018-02-08 | 2018-02-08 | |
| US201862627908P | 2018-02-08 | 2018-02-08 | |
| PCT/IL2019/050151 WO2019155468A1 (en) | 2018-02-08 | 2019-02-07 | Heteroaryl compounds, pharmaceutical compositions thereof, and their therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL276290A true IL276290A (en) | 2020-09-30 |
Family
ID=65635772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL276290A IL276290A (en) | 2018-02-08 | 2020-07-26 | Heteroaryl compounds, their pharmaceutical preparations and their medical use |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20200383984A1 (enExample) |
| EP (1) | EP3749666A1 (enExample) |
| JP (1) | JP2021512922A (enExample) |
| KR (1) | KR20200130287A (enExample) |
| CN (1) | CN111971280A (enExample) |
| AU (1) | AU2019219678A1 (enExample) |
| BR (1) | BR112020016064A2 (enExample) |
| CA (1) | CA3090063A1 (enExample) |
| IL (1) | IL276290A (enExample) |
| MX (1) | MX2020008375A (enExample) |
| WO (1) | WO2019155468A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS62728B1 (sr) | 2015-08-04 | 2022-01-31 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Derivat pirazol pirimidina i njegove upotrebe |
| EP3976600B1 (en) * | 2019-06-03 | 2026-05-20 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Non-hygroscopic crystalline salts of a pyrazole compound, pharmaceutical compositions containing them and their use |
| AU2021209057A1 (en) * | 2020-01-13 | 2022-06-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Pyrazolylpyrimidines and use thereof |
| US20240207268A1 (en) * | 2021-03-24 | 2024-06-27 | Biotheryx, Inc. | Pyrazolylpyrimidines for treating malignant solid tumor |
| US11752151B2 (en) * | 2021-07-12 | 2023-09-12 | Buddhist Tzu Chi Medical Foundation | Method for enhancing hair growth |
| US20230053307A1 (en) * | 2021-07-19 | 2023-02-16 | Buddhist Tzu Chi Medical Foundation | Method for preventing or treating skin disorders and conditions |
| WO2023232245A1 (en) * | 2022-06-01 | 2023-12-07 | Symrise Ag | Fragrances with cyclopropyl structure |
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| RS62728B1 (sr) * | 2015-08-04 | 2022-01-31 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Derivat pirazol pirimidina i njegove upotrebe |
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| JP6799752B2 (ja) * | 2016-10-13 | 2020-12-16 | パナソニックＩｐマネジメント株式会社 | 光ディスク装置、光ディスク読み出し方法 |
| WO2018142393A1 (en) * | 2017-02-01 | 2018-08-09 | Yissum Research Development Company Of The Hebrew | N1 -(4-(5-(cyclopropylmethyl)-1 -methyl-1 h-pyrazol-4-yl)pyridin-2-yl)cyclohexane-1,4-diamine derivatives and related compounds as ck1 and/or iraki inhibitors for treating cancer |
-
2019
- 2019-02-07 KR KR1020207025808A patent/KR20200130287A/ko not_active Ceased
- 2019-02-07 MX MX2020008375A patent/MX2020008375A/es unknown
- 2019-02-07 CA CA3090063A patent/CA3090063A1/en active Pending
- 2019-02-07 BR BR112020016064-4A patent/BR112020016064A2/pt not_active IP Right Cessation
- 2019-02-07 JP JP2020542875A patent/JP2021512922A/ja active Pending
- 2019-02-07 CN CN201980019508.7A patent/CN111971280A/zh active Pending
- 2019-02-07 EP EP19708681.2A patent/EP3749666A1/en not_active Withdrawn
- 2019-02-07 WO PCT/IL2019/050151 patent/WO2019155468A1/en not_active Ceased
- 2019-02-07 AU AU2019219678A patent/AU2019219678A1/en not_active Abandoned
- 2019-02-07 US US16/968,273 patent/US20200383984A1/en not_active Abandoned
-
2020
- 2020-07-26 IL IL276290A patent/IL276290A/en unknown
-
2023
- 2023-01-25 US US18/159,176 patent/US12138265B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20230233562A1 (en) | 2023-07-27 |
| CA3090063A1 (en) | 2019-08-15 |
| CN111971280A (zh) | 2020-11-20 |
| KR20200130287A (ko) | 2020-11-18 |
| AU2019219678A1 (en) | 2020-08-27 |
| BR112020016064A2 (pt) | 2020-12-08 |
| US20200383984A1 (en) | 2020-12-10 |
| WO2019155468A1 (en) | 2019-08-15 |
| JP2021512922A (ja) | 2021-05-20 |
| US12138265B2 (en) | 2024-11-12 |
| EP3749666A1 (en) | 2020-12-16 |
| MX2020008375A (es) | 2020-09-25 |
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