IL272308A - Use of inhaled nitric oxide for the improvement of right and/or left ventricular function - Google Patents

Use of inhaled nitric oxide for the improvement of right and/or left ventricular function

Info

Publication number
IL272308A
IL272308A IL272308A IL27230820A IL272308A IL 272308 A IL272308 A IL 272308A IL 272308 A IL272308 A IL 272308A IL 27230820 A IL27230820 A IL 27230820A IL 272308 A IL272308 A IL 272308A
Authority
IL
Israel
Prior art keywords
left ventricular
nitrous oxide
ventricular activity
improve right
inhaled
Prior art date
Application number
IL272308A
Other languages
English (en)
Hebrew (he)
Original Assignee
Bellerophon Pulse Tech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bellerophon Pulse Tech Llc filed Critical Bellerophon Pulse Tech Llc
Publication of IL272308A publication Critical patent/IL272308A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1025—Respiratory system
    • A61M2210/1039—Lungs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/12—Blood circulatory system
    • A61M2210/125—Heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/30—Blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL272308A 2017-08-30 2020-01-28 Use of inhaled nitric oxide for the improvement of right and/or left ventricular function IL272308A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762552022P 2017-08-30 2017-08-30
US201762611325P 2017-12-28 2017-12-28
PCT/US2018/048524 WO2019046413A1 (en) 2017-08-30 2018-08-29 USE OF INHALED NITRIC OXIDE FOR ENHANCED RIGHT AND / OR LEFT VENTRICULAR FUNCTION

Publications (1)

Publication Number Publication Date
IL272308A true IL272308A (en) 2020-03-31

Family

ID=65526008

Family Applications (2)

Application Number Title Priority Date Filing Date
IL272308A IL272308A (en) 2017-08-30 2020-01-28 Use of inhaled nitric oxide for the improvement of right and/or left ventricular function
IL272314A IL272314A (en) 2017-08-30 2020-01-28 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL272314A IL272314A (en) 2017-08-30 2020-01-28 Use of inhaled nitric oxide for the treatment of pulmonary hypertension associated with lung disease

Country Status (14)

Country Link
US (2) US20200360647A1 (cg-RX-API-DMAC7.html)
EP (2) EP3675840A4 (cg-RX-API-DMAC7.html)
JP (4) JP2020532531A (cg-RX-API-DMAC7.html)
KR (1) KR20200083443A (cg-RX-API-DMAC7.html)
CN (3) CN111372577A (cg-RX-API-DMAC7.html)
AU (2) AU2018324004A1 (cg-RX-API-DMAC7.html)
BR (1) BR112020004205A2 (cg-RX-API-DMAC7.html)
CA (4) CA3266320A1 (cg-RX-API-DMAC7.html)
IL (2) IL272308A (cg-RX-API-DMAC7.html)
MX (2) MX2020002194A (cg-RX-API-DMAC7.html)
PH (1) PH12020500197A1 (cg-RX-API-DMAC7.html)
SG (1) SG11202000893QA (cg-RX-API-DMAC7.html)
TW (3) TW201919590A (cg-RX-API-DMAC7.html)
WO (2) WO2019046415A1 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019009931A (es) 2017-02-27 2020-07-14 Third Pole Inc Sistemas y metodos para generacion ambulatoria de oxido nitrico.
CN113620263A (zh) 2017-02-27 2021-11-09 第三极股份有限公司 生成一氧化氮的系统和方法
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
CN113795291A (zh) * 2019-01-14 2021-12-14 背勒丰治疗公司 Pde-5抑制剂和吸入的一氧化氮的组合药物疗法
WO2020232397A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Electrodes for nitric oxide generation
WO2020232419A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Systems and methods for generating nitric oxide
WO2021142472A1 (en) 2020-01-11 2021-07-15 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US12239460B2 (en) * 2020-05-06 2025-03-04 Janssen Pharmaceuticals, Inc. Controlling operation of drug administration devices using surgical hubs
CN116096446A (zh) * 2020-05-29 2023-05-09 背勒丰治疗公司 脉冲递送气态药物的方法
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2101777T3 (pl) * 2006-12-12 2015-10-30 Gilead Sciences Inc Kompozycja do leczenia nadciśnienia płucnego
WO2009048521A1 (en) * 2007-10-11 2009-04-16 Duke University Potentiating the effect of compound comprising nitric oxide
PT2247297T (pt) * 2008-01-31 2019-04-24 Univ Vanderbilt Tratamento terapêutico para estados pulmonares
CA2671029A1 (en) * 2009-06-30 2010-12-30 James S. Baldassarre Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
WO2012075420A1 (en) * 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
WO2013181322A1 (en) * 2012-05-31 2013-12-05 Ino Therapeutics Llc Methods of administering nitric oxide to arterial or arterialized blood
DK3173116T3 (da) * 2012-12-04 2020-03-02 Mallinckrodt Hospital Products Ip Ltd Kanyle til minimering af fortynding af dosering under indgivelse af nitrogenoxid
US9795756B2 (en) * 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
AU2015204616B2 (en) * 2014-01-10 2020-04-02 Mallinckrodt Hospital Products IP Limited Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
CN106572813B (zh) * 2014-03-28 2020-07-17 沙普医疗系统公司 用于量化慢性疾病的多种可能形式对被报告呼吸困难的患者的贡献的可能性的模式识别系统
WO2017100731A1 (en) * 2015-12-11 2017-06-15 Geno Llc Method and apparatus for administering gases including nitric oxide to address fibrosis
US20170182088A1 (en) * 2015-12-28 2017-06-29 Geno Llc Method and apparatus for administering nitric oxide with supplemental drugs
EP3970730B1 (en) * 2016-02-12 2024-05-01 Mallinckrodt Pharmaceuticals Ireland Limited System for use and monitoring of inhaled nitric oxide with left ventricular assist devices

Also Published As

Publication number Publication date
EP3675719A4 (en) 2021-07-14
CN120131593A (zh) 2025-06-13
CA3073948A1 (en) 2019-03-07
JP2025029093A (ja) 2025-03-05
CN111372577A (zh) 2020-07-03
IL272314A (en) 2020-03-31
EP3675719A1 (en) 2020-07-08
BR112020004205A2 (pt) 2020-09-01
CA3073949A1 (en) 2019-03-07
TW202416939A (zh) 2024-05-01
CA3266267A1 (en) 2025-04-28
CA3266320A1 (en) 2025-05-31
WO2019046413A1 (en) 2019-03-07
JP2023100985A (ja) 2023-07-19
AU2018323547A1 (en) 2020-02-13
AU2018324004A1 (en) 2020-02-13
MX2025004666A (es) 2025-05-02
JP2020532521A (ja) 2020-11-12
US20200188319A1 (en) 2020-06-18
WO2019046415A1 (en) 2019-03-07
PH12020500197A1 (en) 2020-10-19
EP3675840A1 (en) 2020-07-08
TW201919590A (zh) 2019-06-01
MX2020002194A (es) 2020-11-24
TW201912151A (zh) 2019-04-01
SG11202000893QA (en) 2020-02-27
TWI887195B (zh) 2025-06-21
EP3675840A4 (en) 2021-05-12
KR20200083443A (ko) 2020-07-08
CN111315283A (zh) 2020-06-19
JP2020532531A (ja) 2020-11-12
US20200360647A1 (en) 2020-11-19

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