IL27013A - Homologs of n,n'-bis(benzoyloxyalkyl)-piperazine,their preparation and pharmaceutical compositions containing them - Google Patents
Homologs of n,n'-bis(benzoyloxyalkyl)-piperazine,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL27013A IL27013A IL27013A IL2701366A IL27013A IL 27013 A IL27013 A IL 27013A IL 27013 A IL27013 A IL 27013A IL 2701366 A IL2701366 A IL 2701366A IL 27013 A IL27013 A IL 27013A
- Authority
- IL
- Israel
- Prior art keywords
- benzoyloxyalkyl
- homologs
- piperazine
- bis
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/02—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1965A0051095 DE1545575C2 (de) | 1965-12-16 | 1965-12-16 | N, N'-Bis- eckige Klammer auf 3"(3', 4', 5'-trimethoxybenzoyloxy)-propyl eckige Klammer zu -homopiperazin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL27013A true IL27013A (en) | 1970-07-19 |
Family
ID=6937763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL27013A IL27013A (en) | 1965-12-16 | 1966-12-05 | Homologs of n,n'-bis(benzoyloxyalkyl)-piperazine,their preparation and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3532685A (de) |
| AT (1) | AT275527B (de) |
| BE (1) | BE691016A (de) |
| CH (1) | CH476742A (de) |
| CS (1) | CS191151B2 (de) |
| DE (1) | DE1545575C2 (de) |
| DK (1) | DK113291B (de) |
| ES (1) | ES334393A1 (de) |
| FR (1) | FR6053M (de) |
| GB (1) | GB1107470A (de) |
| IL (1) | IL27013A (de) |
| MY (1) | MY7100027A (de) |
| NL (1) | NL153537B (de) |
| SE (1) | SE317977B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3980643A (en) * | 1974-01-04 | 1976-09-14 | Hokuriku Pharmaceutical Co., Ltd. | Novel piperazine- and homopiperazine-monoalkanol esters and a process of production thereof |
| US4035494A (en) * | 1975-10-20 | 1977-07-12 | Sandoz, Inc. | Bis-p-pivaloyl benzylamines |
| DE3403778A1 (de) * | 1984-02-03 | 1985-08-08 | Degussa Ag, 6000 Frankfurt | Cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amin seine verwendung zur herstellung von 1-(3-hydroxy-propyl)-1,4-diazepan und 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)-diazepan |
| JPS60258118A (ja) * | 1984-06-06 | 1985-12-20 | Kowa Co | 抗動脈硬化剤 |
| DE3438289A1 (de) * | 1984-10-19 | 1986-04-24 | Degussa Ag, 6000 Frankfurt | Verfahren zum reinigen von dilazep-base |
| CN1681495B (zh) | 2002-08-19 | 2010-05-12 | 辉瑞产品公司 | 用于治疗过度增生性疾病的组合物 |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
| JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| EP3911648A4 (de) | 2019-01-18 | 2022-10-26 | Astrazeneca AB | Pcsk9-inhibitoren und verfahren zur verwendung davon |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE629910A (de) * | 1962-03-22 | |||
| DE1182239B (de) * | 1962-04-02 | 1964-11-26 | Lentia Gmbh | Verfahren zur Herstellung von Piperazinderivaten |
-
1965
- 1965-12-16 DE DE1965A0051095 patent/DE1545575C2/de not_active Expired
-
1966
- 1966-12-01 DK DK620966AA patent/DK113291B/da unknown
- 1966-12-02 GB GB54090/66A patent/GB1107470A/en not_active Expired
- 1966-12-05 IL IL27013A patent/IL27013A/xx unknown
- 1966-12-05 AT AT1120566A patent/AT275527B/de active
- 1966-12-07 US US599724A patent/US3532685A/en not_active Expired - Lifetime
- 1966-12-10 ES ES0334393A patent/ES334393A1/es not_active Expired
- 1966-12-12 SE SE17000/66A patent/SE317977B/xx unknown
- 1966-12-12 BE BE691016D patent/BE691016A/xx not_active IP Right Cessation
- 1966-12-14 CS CS668008A patent/CS191151B2/cs unknown
- 1966-12-15 CH CH1789566A patent/CH476742A/de not_active IP Right Cessation
- 1966-12-15 NL NL666617653A patent/NL153537B/xx not_active IP Right Cessation
- 1966-12-16 FR FR87720A patent/FR6053M/fr not_active Expired
-
1971
- 1971-12-31 MY MY197127A patent/MY7100027A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1545575B1 (de) | 1970-02-05 |
| NL153537B (nl) | 1977-06-15 |
| ES334393A1 (es) | 1967-11-01 |
| CS191151B2 (en) | 1979-06-29 |
| FR6053M (de) | 1968-05-20 |
| DK113291B (da) | 1969-03-10 |
| MY7100027A (en) | 1971-12-31 |
| CH476742A (de) | 1969-08-15 |
| US3532685A (en) | 1970-10-06 |
| SE317977B (de) | 1969-12-01 |
| DE1545575C2 (de) | 1970-09-10 |
| GB1107470A (en) | 1968-03-27 |
| BE691016A (de) | 1967-06-12 |
| AT275527B (de) | 1969-10-27 |
| NL6617653A (de) | 1967-06-19 |
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