DK113291B - Fremgangsmåde til fremstilling af coronardilatatorisk virksomme diazacycloalkanforbindelser eller syreadditionssalte deraf. - Google Patents

Fremgangsmåde til fremstilling af coronardilatatorisk virksomme diazacycloalkanforbindelser eller syreadditionssalte deraf.

Info

Publication number
DK113291B
DK113291B DK620966AA DK620966A DK113291B DK 113291 B DK113291 B DK 113291B DK 620966A A DK620966A A DK 620966AA DK 620966 A DK620966 A DK 620966A DK 113291 B DK113291 B DK 113291B
Authority
DK
Denmark
Prior art keywords
dilatatorically
coronary
active
preparation
acid addition
Prior art date
Application number
DK620966AA
Other languages
Danish (da)
English (en)
Inventor
H Arnold
K Pahls
R Rebling
N Brock
H Lenke
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of DK113291B publication Critical patent/DK113291B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D245/00Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/02Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK620966AA 1965-12-16 1966-12-01 Fremgangsmåde til fremstilling af coronardilatatorisk virksomme diazacycloalkanforbindelser eller syreadditionssalte deraf. DK113291B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1965A0051095 DE1545575C2 (de) 1965-12-16 1965-12-16 N, N'-Bis- eckige Klammer auf 3"(3', 4', 5'-trimethoxybenzoyloxy)-propyl eckige Klammer zu -homopiperazin

Publications (1)

Publication Number Publication Date
DK113291B true DK113291B (da) 1969-03-10

Family

ID=6937763

Family Applications (1)

Application Number Title Priority Date Filing Date
DK620966AA DK113291B (da) 1965-12-16 1966-12-01 Fremgangsmåde til fremstilling af coronardilatatorisk virksomme diazacycloalkanforbindelser eller syreadditionssalte deraf.

Country Status (14)

Country Link
US (1) US3532685A (de)
AT (1) AT275527B (de)
BE (1) BE691016A (de)
CH (1) CH476742A (de)
CS (1) CS191151B2 (de)
DE (1) DE1545575C2 (de)
DK (1) DK113291B (de)
ES (1) ES334393A1 (de)
FR (1) FR6053M (de)
GB (1) GB1107470A (de)
IL (1) IL27013A (de)
MY (1) MY7100027A (de)
NL (1) NL153537B (de)
SE (1) SE317977B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980643A (en) * 1974-01-04 1976-09-14 Hokuriku Pharmaceutical Co., Ltd. Novel piperazine- and homopiperazine-monoalkanol esters and a process of production thereof
US4035494A (en) * 1975-10-20 1977-07-12 Sandoz, Inc. Bis-p-pivaloyl benzylamines
DE3403778A1 (de) * 1984-02-03 1985-08-08 Degussa Ag, 6000 Frankfurt Cyanomethyl-(2-cyano-ethyl)-(3-hydroxy-propyl)-amin seine verwendung zur herstellung von 1-(3-hydroxy-propyl)-1,4-diazepan und 1,4-bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)-diazepan
JPS60258118A (ja) * 1984-06-06 1985-12-20 Kowa Co 抗動脈硬化剤
DE3438289A1 (de) * 1984-10-19 1986-04-24 Degussa Ag, 6000 Frankfurt Verfahren zum reinigen von dilazep-base
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629910A (de) * 1962-03-22
DE1182239B (de) * 1962-04-02 1964-11-26 Lentia Gmbh Verfahren zur Herstellung von Piperazinderivaten

Also Published As

Publication number Publication date
CH476742A (de) 1969-08-15
IL27013A (en) 1970-07-19
FR6053M (de) 1968-05-20
DE1545575B1 (de) 1970-02-05
CS191151B2 (en) 1979-06-29
US3532685A (en) 1970-10-06
AT275527B (de) 1969-10-27
BE691016A (de) 1967-06-12
DE1545575C2 (de) 1970-09-10
SE317977B (de) 1969-12-01
GB1107470A (en) 1968-03-27
NL153537B (nl) 1977-06-15
MY7100027A (en) 1971-12-31
ES334393A1 (es) 1967-11-01
NL6617653A (de) 1967-06-19

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