|
US5242794A
(en)
|
1984-12-13 |
1993-09-07 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
|
US5019384A
(en)
|
1986-06-30 |
1991-05-28 |
Massachusetts Institute Of Technology |
Immunonodulating compositions and their use
|
|
US4988617A
(en)
|
1988-03-25 |
1991-01-29 |
California Institute Of Technology |
Method of detecting a nucleotide change in nucleic acids
|
|
WO1989012624A2
(en)
|
1988-06-14 |
1989-12-28 |
Cetus Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
US5168038A
(en)
|
1988-06-17 |
1992-12-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
In situ transcription in cells and tissues
|
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5424186A
(en)
|
1989-06-07 |
1995-06-13 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis
|
|
US5242974A
(en)
|
1991-11-22 |
1993-09-07 |
Affymax Technologies N.V. |
Polymer reversal on solid surfaces
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5252743A
(en)
|
1989-11-13 |
1993-10-12 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of anti-ligands on surfaces
|
|
US5494810A
(en)
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
|
US5733523A
(en)
|
1990-12-10 |
1998-03-31 |
Akzo Nobel N.V. |
Targeted delivery of a therapeutic entity using complementary oligonucleotides
|
|
JP3266311B2
(ja)
|
1991-05-02 |
2002-03-18 |
生化学工業株式会社 |
新規ポリペプチドおよびこれを用いる抗hiv剤
|
|
DE69233087T2
(de)
|
1991-11-22 |
2003-12-24 |
Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) |
Verfahren zur Herstellung von Polymerarrays
|
|
US5550215A
(en)
|
1991-11-22 |
1996-08-27 |
Holmes; Christopher P. |
Polymer reversal on solid surfaces
|
|
US5384261A
(en)
|
1991-11-22 |
1995-01-24 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis using mechanically directed flow paths
|
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
|
DE69233528T2
(de)
|
1991-11-25 |
2006-03-16 |
Enzon, Inc. |
Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
|
|
JPH07503132A
(ja)
|
1991-12-17 |
1995-04-06 |
ジェンファーム インターナショナル,インコーポレイティド |
異種抗体を産生することができるトランスジェニック非ヒト動物
|
|
US5491074A
(en)
|
1993-04-01 |
1996-02-13 |
Affymax Technologies Nv |
Association peptides
|
|
US5858659A
(en)
|
1995-11-29 |
1999-01-12 |
Affymetrix, Inc. |
Polymorphism detection
|
|
US5837832A
(en)
|
1993-06-25 |
1998-11-17 |
Affymetrix, Inc. |
Arrays of nucleic acid probes on biological chips
|
|
US5925517A
(en)
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
|
US6090555A
(en)
|
1997-12-11 |
2000-07-18 |
Affymetrix, Inc. |
Scanned image alignment systems and methods
|
|
US5631734A
(en)
|
1994-02-10 |
1997-05-20 |
Affymetrix, Inc. |
Method and apparatus for detection of fluorescently labeled materials
|
|
AU2360195A
(en)
|
1994-05-05 |
1995-11-29 |
Beckman Instruments, Inc. |
Oligonucleotide repeat arrays
|
|
US5571639A
(en)
|
1994-05-24 |
1996-11-05 |
Affymax Technologies N.V. |
Computer-aided engineering system for design of sequence arrays and lithographic masks
|
|
US5795716A
(en)
|
1994-10-21 |
1998-08-18 |
Chee; Mark S. |
Computer-aided visualization and analysis system for sequence evaluation
|
|
US5599695A
(en)
|
1995-02-27 |
1997-02-04 |
Affymetrix, Inc. |
Printing molecular library arrays using deprotection agents solely in the vapor phase
|
|
US5750341A
(en)
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
|
US5624711A
(en)
|
1995-04-27 |
1997-04-29 |
Affymax Technologies, N.V. |
Derivatization of solid supports and methods for oligomer synthesis
|
|
SE504798C2
(sv)
|
1995-06-16 |
1997-04-28 |
Ulf Landegren |
Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
|
|
US5968740A
(en)
|
1995-07-24 |
1999-10-19 |
Affymetrix, Inc. |
Method of Identifying a Base in a Nucleic Acid
|
|
US6852487B1
(en)
|
1996-02-09 |
2005-02-08 |
Cornell Research Foundation, Inc. |
Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
|
|
EP0902885A4
(en)
|
1996-05-16 |
2006-09-27 |
Affymetrix Inc |
SYSTEMS AND METHODS FOR DETECTION OF BRANDED PRODUCTS
|
|
AU730633B2
(en)
|
1996-05-29 |
2001-03-08 |
Phillip Belgrader |
Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
|
|
DE69739357D1
(de)
|
1996-06-04 |
2009-05-28 |
Univ Utah Res Found |
Überwachung der hybridisierung während pcr
|
|
GB9703369D0
(en)
|
1997-02-18 |
1997-04-09 |
Lindqvist Bjorn H |
Process
|
|
DK0985032T4
(da)
|
1997-05-28 |
2009-08-31 |
Crescendo Biolog Ltd |
Ribosom-komplekser som selektionspartikler til in vitro fremvisning og evolution af proteiner
|
|
JP2001521753A
(ja)
|
1997-10-31 |
2001-11-13 |
アフィメトリックス インコーポレイテッド |
成人臓器及び胎児臓器中の発現プロフィール
|
|
US6428752B1
(en)
|
1998-05-14 |
2002-08-06 |
Affymetrix, Inc. |
Cleaning deposit devices that form microarrays and the like
|
|
US6269846B1
(en)
|
1998-01-13 |
2001-08-07 |
Genetic Microsystems, Inc. |
Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
|
|
US6054276A
(en)
|
1998-02-23 |
2000-04-25 |
Macevicz; Stephen C. |
DNA restriction site mapping
|
|
US5936324A
(en)
|
1998-03-30 |
1999-08-10 |
Genetic Microsystems Inc. |
Moving magnet scanner
|
|
US6780591B2
(en)
|
1998-05-01 |
2004-08-24 |
Arizona Board Of Regents |
Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
|
|
JP3813818B2
(ja)
|
1998-05-01 |
2006-08-23 |
アリゾナ ボード オブ リージェンツ |
オリゴヌクレオチドおよびdna分子のヌクレオチド配列の決定方法
|
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
|
CA2366459A1
(en)
|
1999-03-26 |
2000-10-05 |
Affymetrix, Inc. |
Universal arrays
|
|
US6582938B1
(en)
|
2001-05-11 |
2003-06-24 |
Affymetrix, Inc. |
Amplification of nucleic acids
|
|
US7306904B2
(en)
|
2000-02-18 |
2007-12-11 |
Olink Ab |
Methods and kits for proximity probing
|
|
US6686184B1
(en)
|
2000-05-25 |
2004-02-03 |
President And Fellows Of Harvard College |
Patterning of surfaces utilizing microfluidic stamps including three-dimensionally arrayed channel networks
|
|
PT1421115E
(pt)
|
2001-08-31 |
2005-07-29 |
Avidex Ltd |
Receptor de celulas t soluvel
|
|
GB0127564D0
(en)
|
2001-11-16 |
2002-01-09 |
Medical Res Council |
Emulsion compositions
|
|
JP2006507921A
(ja)
|
2002-06-28 |
2006-03-09 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
流体分散のための方法および装置
|
|
AU2003271904B2
(en)
|
2002-10-09 |
2009-03-05 |
Adaptimmune Limited |
Single chain recombinant T cell receptors
|
|
US20060078893A1
(en)
|
2004-10-12 |
2006-04-13 |
Medical Research Council |
Compartmentalised combinatorial chemistry by microfluidic control
|
|
CA2521862C
(en)
|
2003-04-10 |
2012-10-16 |
President And Fellows Of Harvard College |
Formation and control of fluidic species
|
|
CN1842368B
(zh)
|
2003-08-27 |
2014-05-28 |
哈佛大学 |
流体物种的电子控制
|
|
US7169560B2
(en)
|
2003-11-12 |
2007-01-30 |
Helicos Biosciences Corporation |
Short cycle methods for sequencing polynucleotides
|
|
US20050221339A1
(en)
|
2004-03-31 |
2005-10-06 |
Medical Research Council Harvard University |
Compartmentalised screening by microfluidic control
|
|
US7643818B2
(en)
|
2004-11-22 |
2010-01-05 |
Seven Networks, Inc. |
E-mail messaging to/from a mobile terminal
|
|
US9039273B2
(en)
|
2005-03-04 |
2015-05-26 |
President And Fellows Of Harvard College |
Method and apparatus for forming multiple emulsions
|
|
WO2007081410A2
(en)
|
2005-09-13 |
2007-07-19 |
True Materials Incorporated |
Encoded microparticles
|
|
WO2007081385A2
(en)
|
2006-01-11 |
2007-07-19 |
Raindance Technologies, Inc. |
Microfluidic devices and methods of use in the formation and control of nanoreactors
|
|
WO2007089541A2
(en)
|
2006-01-27 |
2007-08-09 |
President And Fellows Of Harvard College |
Fluidic droplet coalescence
|
|
GB0605584D0
(en)
|
2006-03-20 |
2006-04-26 |
Olink Ab |
Method for analyte detection using proximity probes
|
|
WO2007133710A2
(en)
|
2006-05-11 |
2007-11-22 |
Raindance Technologies, Inc. |
Microfluidic devices and methods of use thereof
|
|
EP2173509A4
(en)
|
2007-06-25 |
2013-11-06 |
Affymetrix Inc |
STRUCTURED MICROCODES
|
|
EP3150727B1
(en)
|
2008-04-30 |
2019-07-10 |
Integrated DNA Technologies Inc. |
Rnase-h-based assays utilizing modified rna monomers
|
|
US8911948B2
(en)
|
2008-04-30 |
2014-12-16 |
Integrated Dna Technologies, Inc. |
RNase H-based assays utilizing modified RNA monomers
|
|
GB2502409B8
(en)
|
2008-09-23 |
2014-10-15 |
Bio Rad Laboratories |
Droplet-based assay system
|
|
WO2011044186A1
(en)
|
2009-10-06 |
2011-04-14 |
The Board Of Trustees Of The University Of Illinois |
Human single-chain t cell receptors
|
|
CA2907050C
(en)
*
|
2013-03-15 |
2023-09-26 |
Prognosys Biosciences, Inc. |
Methods for detecting peptide/mhc/tcr binding
|
|
WO2014144495A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Abvitro, Inc. |
Single cell bar-coding for antibody discovery
|
|
AU2015271324B2
(en)
*
|
2014-06-06 |
2019-09-12 |
Herlev Hospital |
Determining antigen recognition through barcoding of MHC multimers
|
|
US10590483B2
(en)
*
|
2014-09-15 |
2020-03-17 |
Abvitro Llc |
High-throughput nucleotide library sequencing
|
|
EP3234130B1
(en)
*
|
2014-12-19 |
2020-11-25 |
The Broad Institute, Inc. |
Methods for profiling the t-cell- receptor repertoire
|