SG11201609490QA - Polymer-flavonoid conjugate and uses thereof - Google Patents
Polymer-flavonoid conjugate and uses thereofInfo
- Publication number
- SG11201609490QA SG11201609490QA SG11201609490QA SG11201609490QA SG11201609490QA SG 11201609490Q A SG11201609490Q A SG 11201609490QA SG 11201609490Q A SG11201609490Q A SG 11201609490QA SG 11201609490Q A SG11201609490Q A SG 11201609490QA SG 11201609490Q A SG11201609490Q A SG 11201609490QA
- Authority
- SG
- Singapore
- Prior art keywords
- polymer
- flavonoid conjugate
- flavonoid
- conjugate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Materials Engineering (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG11201609490QA SG11201609490QA (en) | 2014-05-15 | 2015-05-15 | Polymer-flavonoid conjugate and uses thereof |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG10201402361X | 2014-05-15 | ||
SG11201609490QA SG11201609490QA (en) | 2014-05-15 | 2015-05-15 | Polymer-flavonoid conjugate and uses thereof |
PCT/SG2015/050117 WO2015174934A1 (en) | 2014-05-15 | 2015-05-15 | Polymer-flavonoid conjugate and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201609490QA true SG11201609490QA (en) | 2016-12-29 |
Family
ID=54480328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201609490QA SG11201609490QA (en) | 2014-05-15 | 2015-05-15 | Polymer-flavonoid conjugate and uses thereof |
Country Status (6)
Country | Link |
---|---|
US (1) | US10406175B2 (en) |
EP (1) | EP3142705B1 (en) |
JP (1) | JP6661546B2 (en) |
CN (1) | CN106456797A (en) |
SG (1) | SG11201609490QA (en) |
WO (1) | WO2015174934A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10716959B2 (en) | 2013-09-03 | 2020-07-21 | Agency For Science, Technology And Research | Polymer-flavonoid conjugates and hydrogels for biomedical applications |
CN105381470B (en) * | 2015-11-27 | 2018-11-02 | 广东医科大学 | A kind of modified dye lignin and its application |
EP3578573A4 (en) * | 2017-02-02 | 2020-11-18 | Amtixbio Co., Ltd. | Hydrogel using, as substrate, hyaluronic acid derivative modified with gallol group and use thereof |
KR20190050416A (en) | 2017-11-03 | 2019-05-13 | 전북대학교산학협력단 | Composition for Gellan-gum Hydrogels Containing miRNA-140-5p and Composition for treatment of Cartilage Regeneration using it |
US20210017348A1 (en) * | 2018-04-02 | 2021-01-21 | Optipharm Co., Ltd | Alginate microcapsules for cell encapsulation and, manufacturing method therefor |
KR102076769B1 (en) * | 2018-04-24 | 2020-02-12 | 바이오스트림테크놀러지스(주) | Hyaluronic acid-flavonoid conjugate, nanoparticle comprising same and manufacturing method thereof |
KR102181502B1 (en) * | 2018-08-17 | 2020-11-23 | 한양대학교 산학협력단 | Preparation method of polymer complex coated with epigallocatechin gallate and the polymer complex prepared by the same method |
KR102156602B1 (en) | 2019-10-17 | 2020-09-16 | 전북대학교산학협력단 | Composition for Gellan-gum Hydrogels Containing miRNA-140-5p and Composition for treatment of Cartilage Regeneration using it |
KR102440783B1 (en) * | 2020-06-15 | 2022-09-06 | 한양대학교 산학협력단 | Preparation method of organic-inorganic complex coated with mineral particle based on polyphenol and organic-inorganic complex prepared by the method |
CN115702937A (en) * | 2021-08-04 | 2023-02-17 | 四川大学 | Modified polyphenol carrier material, targeted nano delivery system, preparation method and application |
CA3227319A1 (en) * | 2021-09-16 | 2023-03-23 | Coval Biopharma (Shanghai) Co., Ltd. | Drug delivery system for locally delivering therapeutic agents and uses thereof |
CN114259602B (en) * | 2021-12-29 | 2022-09-30 | 江苏江山聚源生物技术有限公司 | Recombinant collagen hydrogel for injection and preparation method thereof |
CN114366710B (en) * | 2022-01-20 | 2023-11-17 | 苏州大学附属第一医院 | Application of injectable burdock microcarrier in treating advanced osteoarthritis |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8713662D0 (en) | 1987-06-11 | 1987-07-15 | Skandigen Ab | Hyaluronic acid derivatives |
FR2699819B1 (en) | 1992-12-28 | 1995-02-24 | Dolisos Lab | Use of prodelphinidins for obtaining medicaments intended for the treatment of osteoarthritis. |
JPH07238079A (en) * | 1994-02-25 | 1995-09-12 | Lotte Co Ltd | Catechin compound, its production and deodorant using the same |
EP1207862A2 (en) * | 1999-06-07 | 2002-05-29 | The University Of Sheffield | Arthritis treatment |
US6428817B1 (en) | 1999-07-06 | 2002-08-06 | Peter Donald Collin | Companion animal therapeutic treat |
WO2003080593A1 (en) * | 2002-03-22 | 2003-10-02 | Beijing Jiankai Technology Co., Ltd. | Hydrophilic polymers-flavonoids conjugates and pharmaceutical compositions comprising them |
EP1888651B1 (en) | 2005-05-20 | 2014-07-30 | Agency for Science, Technology and Research | Aldehyde conjugated flavonoid preparations |
US7858080B2 (en) | 2005-05-20 | 2010-12-28 | Agency For Science, Technology And Research | Aldehyde conjugated flavonoid preparations |
EP2464388B1 (en) * | 2009-08-11 | 2017-05-10 | Agency for Science, Technology and Research | Particulate hyaluronic acid formulations for cellular delivery of bioactive agents |
ES2698901T3 (en) | 2011-04-13 | 2019-02-06 | Akonni Biosystems Inc | Sample detection system based on microarrays |
WO2013063086A1 (en) | 2011-10-24 | 2013-05-02 | Intellect Neurosciences, Inc. | Compositions and methods for treatment of proteinopathies |
US10716959B2 (en) | 2013-09-03 | 2020-07-21 | Agency For Science, Technology And Research | Polymer-flavonoid conjugates and hydrogels for biomedical applications |
GB2518405A (en) * | 2013-09-20 | 2015-03-25 | Zeiss Carl Meditec Ag | Composition comprising at least one viscoelastic polymer |
-
2015
- 2015-05-15 SG SG11201609490QA patent/SG11201609490QA/en unknown
- 2015-05-15 CN CN201580029666.2A patent/CN106456797A/en active Pending
- 2015-05-15 JP JP2016567350A patent/JP6661546B2/en not_active Expired - Fee Related
- 2015-05-15 WO PCT/SG2015/050117 patent/WO2015174934A1/en active Application Filing
- 2015-05-15 US US15/308,725 patent/US10406175B2/en not_active Expired - Fee Related
- 2015-05-15 EP EP15792453.1A patent/EP3142705B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20170216446A1 (en) | 2017-08-03 |
EP3142705A4 (en) | 2017-11-22 |
WO2015174934A9 (en) | 2016-06-09 |
US10406175B2 (en) | 2019-09-10 |
EP3142705A1 (en) | 2017-03-22 |
JP2017515834A (en) | 2017-06-15 |
EP3142705B1 (en) | 2020-08-19 |
JP6661546B2 (en) | 2020-03-11 |
WO2015174934A1 (en) | 2015-11-19 |
CN106456797A (en) | 2017-02-22 |
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