IL262305B - Azasterone for use in the treatment of disorders related to the ear - Google Patents
Azasterone for use in the treatment of disorders related to the earInfo
- Publication number
- IL262305B IL262305B IL262305A IL26230518A IL262305B IL 262305 B IL262305 B IL 262305B IL 262305 A IL262305 A IL 262305A IL 26230518 A IL26230518 A IL 26230518A IL 262305 B IL262305 B IL 262305B
- Authority
- IL
- Israel
- Prior art keywords
- azasetron
- treatment
- ear disorders
- ear
- disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322690P | 2016-04-14 | 2016-04-14 | |
| EP16180192 | 2016-07-19 | ||
| PCT/EP2017/059058 WO2017178645A1 (en) | 2016-04-14 | 2017-04-14 | (+)-azasetron for use in the treatment of ear disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL262305A IL262305A (en) | 2018-11-29 |
| IL262305B true IL262305B (en) | 2022-03-01 |
Family
ID=65588799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL262305A IL262305B (en) | 2016-04-14 | 2018-10-11 | Azasterone for use in the treatment of disorders related to the ear |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US11612605B2 (https=) |
| EP (1) | EP4335508A3 (https=) |
| JP (1) | JP7158723B2 (https=) |
| CN (1) | CN109310698B (https=) |
| AU (1) | AU2023202897B2 (https=) |
| CL (1) | CL2018002930A1 (https=) |
| DK (1) | DK3442537T3 (https=) |
| ES (1) | ES2975016T3 (https=) |
| FI (1) | FI3442537T3 (https=) |
| HR (1) | HRP20240453T1 (https=) |
| HU (1) | HUE066000T2 (https=) |
| IL (1) | IL262305B (https=) |
| MX (1) | MX384045B (https=) |
| NZ (1) | NZ747201A (https=) |
| PL (1) | PL3442537T3 (https=) |
| RS (1) | RS65379B1 (https=) |
| SI (1) | SI3442537T1 (https=) |
| ZA (1) | ZA201806894B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2882602T3 (es) * | 2015-05-18 | 2021-12-02 | Sensorion | Azasetrón para usar en el tratamiento de la pérdida auditiva |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695578A (en) | 1984-01-25 | 1987-09-22 | Glaxo Group Limited | 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances |
| US5360800A (en) | 1987-09-03 | 1994-11-01 | Glaxo Group Limited | Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives |
| CA1304082C (en) | 1987-10-22 | 1992-06-23 | Tetsuya Tahara | Benzoxazine compounds and pharmaceutical use thereof |
| GB9423511D0 (en) | 1994-11-22 | 1995-01-11 | Glaxo Wellcome Inc | Compositions |
| GB0009914D0 (en) | 2000-04-20 | 2000-06-07 | Metris Therapeutics Limited | Device |
| GB0104554D0 (en) | 2001-02-23 | 2001-04-11 | Glaxo Group Ltd | New uses |
| US20030044356A1 (en) | 2001-04-20 | 2003-03-06 | Jin Auh | Composition for nasal solution sprays having effective component of 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one) |
| US20030229333A1 (en) * | 2002-02-22 | 2003-12-11 | Control Delivery Systems, Inc. | Methods for treating otic disorders |
| GB0213869D0 (en) | 2002-06-17 | 2002-07-31 | Arakis Ltd | The treatment of pain |
| NZ541009A (en) | 2003-01-13 | 2007-09-28 | Dynogen Pharmaceuticals Inc | Method of treating nausea, vomiting, retching or any combination thereof |
| TWI355936B (en) | 2003-02-18 | 2012-01-11 | Helsinn Healthcare Sa | Uses of palonosetron hydrochloride |
| US20040204466A1 (en) | 2003-04-14 | 2004-10-14 | Orchid Chemicals And Pharmaceuticals Ltd. | Treatment of bronchial asthma using 5-HT3 receptor antagonists |
| US20070265329A1 (en) | 2006-05-12 | 2007-11-15 | Devang Shah T | Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) |
| EP2725035A1 (en) | 2007-10-02 | 2014-04-30 | Avaxia Biologics, Inc. | Antibody therapy for use in the digestive tract |
| US20100016218A1 (en) | 2008-07-14 | 2010-01-21 | Otonomy, Inc. | Controlled-release apoptosis modulating compositions and methods for the treatment of otic disorders |
| EP2253316B1 (en) * | 2009-05-20 | 2013-08-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Serotonin 5-HT3 receptor antagonists for use in the treatment or prevention of an inner ear pathology with vestibular deficits |
| CN102458400B (zh) | 2009-05-20 | 2014-10-08 | 国立健康与医学研究所 | 用于治疗病灶性前庭功能障碍的血清素5-ht3受体拮抗剂 |
| CN101786963B (zh) | 2010-03-03 | 2013-05-08 | 山东众诚药业股份有限公司 | 阿扎司琼中间体的合成方法 |
| JP2015511242A (ja) | 2012-02-23 | 2015-04-16 | インセルム（インスティチュート ナショナル デ ラ サンテ エ デ ラリシェルシェ メディカル） | 病変性前庭障害の治療に使用するカルシニューリン阻害剤 |
| EP2872128B1 (en) | 2012-07-16 | 2020-02-19 | Cornell University | Nicotinamide riboside to treat hearing loss |
| BR112016002205A2 (pt) * | 2013-07-31 | 2017-08-01 | Bluepharma Ind Farmaceutica S A | filmes orodispersíveis |
| CN104557906A (zh) | 2015-01-21 | 2015-04-29 | 扬子江药业集团四川海蓉药业有限公司 | 一种盐酸阿扎司琼的制备方法 |
| ES2882602T3 (es) * | 2015-05-18 | 2021-12-02 | Sensorion | Azasetrón para usar en el tratamiento de la pérdida auditiva |
-
2017
- 2017-04-14 RS RS20240412A patent/RS65379B1/sr unknown
- 2017-04-14 EP EP23220392.7A patent/EP4335508A3/en not_active Withdrawn
- 2017-04-14 SI SI201731500T patent/SI3442537T1/sl unknown
- 2017-04-14 US US16/093,911 patent/US11612605B2/en active Active
- 2017-04-14 DK DK17717441.4T patent/DK3442537T3/da active
- 2017-04-14 PL PL17717441.4T patent/PL3442537T3/pl unknown
- 2017-04-14 FI FIEP17717441.4T patent/FI3442537T3/fi active
- 2017-04-14 ES ES17717441T patent/ES2975016T3/es active Active
- 2017-04-14 CN CN201780036585.4A patent/CN109310698B/zh active Active
- 2017-04-14 NZ NZ747201A patent/NZ747201A/en unknown
- 2017-04-14 MX MX2018012587A patent/MX384045B/es unknown
- 2017-04-14 HR HRP20240453TT patent/HRP20240453T1/hr unknown
- 2017-04-14 HU HUE17717441A patent/HUE066000T2/hu unknown
- 2017-04-14 JP JP2018553953A patent/JP7158723B2/ja active Active
-
2018
- 2018-10-11 IL IL262305A patent/IL262305B/en unknown
- 2018-10-12 CL CL2018002930A patent/CL2018002930A1/es unknown
- 2018-10-16 ZA ZA2018/06894A patent/ZA201806894B/en unknown
-
2023
- 2023-03-13 US US18/182,511 patent/US20230226071A1/en active Pending
- 2023-05-09 AU AU2023202897A patent/AU2023202897B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK3442537T3 (da) | 2024-03-25 |
| EP4335508A3 (en) | 2024-07-10 |
| US20230226071A1 (en) | 2023-07-20 |
| NZ747201A (en) | 2023-02-24 |
| JP7158723B2 (ja) | 2022-10-24 |
| US20190083503A1 (en) | 2019-03-21 |
| JP2019513780A (ja) | 2019-05-30 |
| EP4335508A2 (en) | 2024-03-13 |
| FI3442537T3 (fi) | 2024-04-04 |
| HUE066000T2 (hu) | 2024-06-28 |
| US11612605B2 (en) | 2023-03-28 |
| IL262305A (en) | 2018-11-29 |
| HRP20240453T1 (hr) | 2024-06-21 |
| MX2018012587A (es) | 2019-03-07 |
| AU2023202897B2 (en) | 2025-01-30 |
| CL2018002930A1 (es) | 2019-02-15 |
| ES2975016T3 (es) | 2024-07-02 |
| SI3442537T1 (sl) | 2024-05-31 |
| CN109310698B (zh) | 2021-12-24 |
| MX384045B (es) | 2025-03-14 |
| PL3442537T3 (pl) | 2024-07-15 |
| ZA201806894B (en) | 2023-03-29 |
| RS65379B1 (sr) | 2024-04-30 |
| AU2023202897A1 (en) | 2023-05-25 |
| CN109310698A (zh) | 2019-02-05 |
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