IL244236A0 - Oligonucleotide probes and their uses - Google Patents
Oligonucleotide probes and their usesInfo
- Publication number
- IL244236A0 IL244236A0 IL244236A IL24423616A IL244236A0 IL 244236 A0 IL244236 A0 IL 244236A0 IL 244236 A IL244236 A IL 244236A IL 24423616 A IL24423616 A IL 24423616A IL 244236 A0 IL244236 A0 IL 244236A0
- Authority
- IL
- Israel
- Prior art keywords
- oligonucleotide probes
- oligonucleotide
- probes
- Prior art date
Links
- 108020005187 Oligonucleotide Probes Proteins 0.000 title 1
- 239000002751 oligonucleotide probe Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/205—Aptamer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361871107P | 2013-08-28 | 2013-08-28 | |
| US201361874621P | 2013-09-06 | 2013-09-06 | |
| US201361900975P | 2013-11-06 | 2013-11-06 | |
| US201361912471P | 2013-12-05 | 2013-12-05 | |
| US201461924192P | 2014-01-06 | 2014-01-06 | |
| US201461949216P | 2014-03-06 | 2014-03-06 | |
| US201461974949P | 2014-04-03 | 2014-04-03 | |
| US201461990085P | 2014-05-07 | 2014-05-07 | |
| US201461994704P | 2014-05-16 | 2014-05-16 | |
| US201462024436P | 2014-07-14 | 2014-07-14 | |
| PCT/US2014/053306 WO2015031694A2 (en) | 2013-08-28 | 2014-08-28 | Oligonucleotide probes and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL244236A0 true IL244236A0 (en) | 2016-04-21 |
Family
ID=52587490
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL244236A IL244236A0 (en) | 2013-08-28 | 2016-02-22 | Oligonucleotide probes and their uses |
| IL26969319A IL269693A (en) | 2013-08-28 | 2019-09-26 | Oligonucleotide probes and their uses |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL26969319A IL269693A (en) | 2013-08-28 | 2019-09-26 | Oligonucleotide probes and their uses |
Country Status (10)
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9599611B2 (en) | 2005-04-25 | 2017-03-21 | Trustees Of Boston University | Structured substrates for optical surface profiling |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| AU2013340414B2 (en) | 2012-10-23 | 2019-05-02 | Caris Science, Inc. | Aptamers and uses thereof |
| AU2013361323B2 (en) | 2012-12-19 | 2018-09-06 | Caris Science, Inc. | Compositions and methods for aptamer screening |
| SI3083997T1 (sl) * | 2013-12-20 | 2020-12-31 | Universite De Lausanne | Diagnostične, prognostične in terapevtske uporabe dolgih nekodirajočih RNA-jev za srčno bolezen in regenerativno zdravilo |
| US10444247B2 (en) * | 2014-09-17 | 2019-10-15 | Wallac Oy | Method for determining the risk of preterm birth |
| US20180066262A1 (en) | 2015-03-09 | 2018-03-08 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| BR112017024552A2 (pt) | 2015-05-21 | 2018-07-24 | Univ Indiana Res & Tech Corp | métodos para direcionar ape1/ref-1 para inibir os genes de sinalização da hipóxia |
| WO2017004243A1 (en) | 2015-06-29 | 2017-01-05 | Caris Science, Inc. | Therapeutic oligonucleotides |
| US10941176B2 (en) | 2015-07-28 | 2021-03-09 | Caris Science, Inc. | Therapeutic oligonucleotides |
| JP6921809B2 (ja) | 2015-09-22 | 2021-08-18 | トラスティーズ オブ ボストン ユニバーシティ | ナノ小胞の多重表現型決定法 |
| US11230735B2 (en) * | 2015-12-24 | 2022-01-25 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Systems and methods for characterizing sepsis |
| AU2017214541B2 (en) | 2016-02-05 | 2024-03-21 | NanoView Biosciences, Inc. | Detection of exosomes having surface markers |
| AU2017235661B2 (en) | 2016-03-18 | 2023-06-08 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| KR102516168B1 (ko) | 2016-05-02 | 2023-03-30 | 엔코디아, 인코포레이티드 | 암호화 핵산을 사용한 거대분자 분석 |
| IL298701B2 (en) * | 2016-05-25 | 2024-03-01 | Caris Science Inc | Oligonucleotide probes and uses thereof |
| AU2017285350A1 (en) | 2016-06-17 | 2018-12-20 | F. Hoffmann-La Roche Ag | Nucleic acid molecules for reduction of PAPD5 or PAPD7 mRNA for treating hepatitis B infection |
| US20190276828A1 (en) * | 2016-10-25 | 2019-09-12 | Purdue Research Foundation | Conjugates for sensing |
| KR20180048420A (ko) * | 2016-11-02 | 2018-05-10 | 김성천 | 차세대서열결정법을 이용한 표적 단백질의 집단적 정량 방법과 그 용도 |
| AU2018266848A1 (en) * | 2017-05-08 | 2019-11-21 | Augmanity Nano Ltd | Treatment of rapidly evolving biological entities |
| CN110662844A (zh) * | 2017-05-22 | 2020-01-07 | 内盖夫生物技术国家研究所有限公司 | 用于肺癌的诊断的生物标志物 |
| US11667978B2 (en) | 2017-06-07 | 2023-06-06 | Gen-Probe Incorporated | Detecting Babesia species nucleic acid in a sample |
| CN109251980A (zh) * | 2017-07-14 | 2019-01-22 | 中国人民解放军第八医院 | 膀胱癌组织t细胞图谱模型及其构建方法和构建系统 |
| JP2019020206A (ja) * | 2017-07-14 | 2019-02-07 | 株式会社島津製作所 | 質量分析を用いた認知機能障害疾患バイオマーカーの定量方法及び質量分析装置 |
| EP3690434A4 (en) * | 2017-09-27 | 2021-05-26 | Rosetta Exosome | Analysis method for extracellular vesicles, using size exclusion chromatography, and use for same |
| KR20200030594A (ko) | 2017-10-16 | 2020-03-20 | 에프. 호프만-라 로슈 아게 | B형 간염 감염을 치료하기 위한 PAPD5 및 PAPD7 mRNA의 감소용 핵산 분자 |
| MX2020004559A (es) | 2017-10-31 | 2020-10-05 | Encodia Inc | Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico. |
| CN108866215B (zh) * | 2017-12-01 | 2022-02-08 | 苏州百源基因技术有限公司 | 一种用于产气肠杆菌检测的实时荧光定量pcr试剂盒 |
| CN111684078B (zh) * | 2018-02-12 | 2024-04-19 | 豪夫迈·罗氏有限公司 | 通过评价肿瘤遗传异质性来预测对治疗的应答的方法 |
| EP3803332A1 (en) | 2018-06-01 | 2021-04-14 | NanoView Biosciences, Inc. | Compositions, systems, and methods for enhanced label-free and fluorescence - based detection of nanoparticles |
| GB201810571D0 (en) * | 2018-06-27 | 2018-08-15 | Cs Genetics Ltd | Reagents and methods for the analysis of circulating microparticles |
| TWI862501B (zh) | 2018-07-03 | 2024-11-21 | 瑞士商赫孚孟拉羅股份公司 | 用於調制 Tau 表現之寡核苷酸 |
| KR20210031927A (ko) * | 2018-07-17 | 2021-03-23 | 유니버시티 오브 워싱톤 | 압타머 기반 가역적 세포 선택과 관련된 조성물 및 방법 |
| EP3827082B1 (en) * | 2018-07-26 | 2025-05-14 | Bracco Imaging SpA | Icam-1 aptamers, diagnostic and therapeutic uses thereof |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| US11608356B1 (en) * | 2019-02-22 | 2023-03-21 | Base Pair Biotechnologies, Inc. | Functional ligands to colistin |
| CA3129868A1 (en) * | 2019-03-01 | 2020-09-10 | Mercy Bioanalytics, Inc. | Systems, compositions, and methods for target entity detection |
| CN109880903B (zh) * | 2019-03-01 | 2021-12-14 | 南京医科大学 | 一种用于非小细胞肺癌辅助诊断的snp标志物及其应用 |
| CN110045099B (zh) * | 2019-04-01 | 2022-03-04 | 四川大学华西医院 | 一种慢性阻塞性肺疾病检测试剂盒 |
| US12618074B2 (en) | 2019-04-11 | 2026-05-05 | The Board Of Trustees Of The University Of Arkansas | CD40 specific DNA aptamers as vaccine adjuvants |
| US12434236B2 (en) | 2019-04-26 | 2025-10-07 | The Johns Hopkins University | Methods and materials for treating cancer |
| EP3963070A4 (en) | 2019-04-30 | 2023-02-22 | Encodia, Inc. | METHODS OF PREPARATION OF ANALYTES AND RELATED KITS |
| CN110412281B (zh) * | 2019-06-26 | 2022-09-09 | 四川大学华西医院 | Begain自身抗体检测试剂在制备肺癌筛查试剂盒中的用途 |
| US12613245B2 (en) | 2019-10-15 | 2026-04-28 | Cornell University | Methods for detecting and inhibiting brain metastasis |
| WO2021183893A1 (en) | 2020-03-13 | 2021-09-16 | The Translational Genomics Research Institute | Methods and kits for the detection of sars-cov-2 |
| CA3178255A1 (en) * | 2020-05-15 | 2021-11-18 | Krishna KANNAN | On demand synthesis of polynucleotide sequences |
| CN115667925A (zh) * | 2020-05-15 | 2023-01-31 | 阿雷克森制药公司 | 使用细胞外囊泡来检测补体激活的方法以及其用于评估和/或监测补体介导的疾病的治疗的用途 |
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| MX2022016049A (es) | 2020-06-25 | 2023-02-09 | Procter & Gamble | Aptameros para aplicaciones para el cuidado personal de la salud. |
| CN111830289B (zh) * | 2020-07-24 | 2023-01-03 | 长春理工大学 | 一种利用原子力显微术对生物素化抗体-IgE免疫复合物直接成像的方法 |
| WO2022032227A1 (en) * | 2020-08-07 | 2022-02-10 | The Board Of Trustees Of The University Of Arkansas | Nasal microbiome biomarkers for predicting the onset of bovine respiratory disease and treating the same |
| JP7623124B2 (ja) * | 2020-10-20 | 2025-01-28 | 大塚製薬株式会社 | 細胞外小胞の内包物の測定方法および測定キット |
| CN112535886B (zh) * | 2020-11-12 | 2022-07-12 | 杭州苏铂科技有限公司 | 去除金纳米棒溶液中的ctab的方法 |
| WO2022216920A1 (en) | 2021-04-08 | 2022-10-13 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of receptor for advanced glycation end-products, compositions thereof, and methods of use |
| WO2023028035A1 (en) * | 2021-08-23 | 2023-03-02 | University Of Florida Research Foundation, Incorporated | Lipid enveloped recombinant aav particles for gene therapy use |
| KR102971055B1 (ko) * | 2021-12-03 | 2026-05-29 | 주식회사 녹십자 | 번역 효율이 향상된 5'-utr, 이를 포함하는 합성 핵산 분자 및 이를 포함하는 백신 또는 치료제 조성물 |
| CN117451995A (zh) * | 2021-12-06 | 2024-01-26 | 上海市精神卫生中心（上海市心理咨询培训中心） | 用于预测应激后精神心理症状发生的免疫检测试剂盒及应用 |
| CN114438191B (zh) * | 2022-01-27 | 2024-04-30 | 宁波大学 | 缺氧诱导因子1α作为标志物在抑郁症复发诊断中的应用 |
| CN114410773B (zh) * | 2022-01-27 | 2024-05-03 | 宁波大学 | 用于预测或诊断抑郁症复发的标志物组合及其应用 |
| CN119522134A (zh) * | 2022-05-18 | 2025-02-25 | 生物辐射实验室股份有限公司 | 用于自动化数字聚合酶链式反应的系统和方法 |
| CN115754293A (zh) * | 2022-11-07 | 2023-03-07 | 四川大学华西第二医院 | Vwf糖基化蛋白的检测试剂在制备筛查患肺癌风险的试剂盒中的用途 |
| US20260139318A1 (en) * | 2022-11-17 | 2026-05-21 | Universite De Poitiers | Method for determining microsatellite instability status, kits and uses thereof |
| CN116286834A (zh) * | 2023-03-01 | 2023-06-23 | 武汉大学中南医院 | 一种特异性识别sST2蛋白的核酸适配体及其应用 |
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| KR102994414B1 (ko) | 2024-08-27 | 2026-07-23 | 경상국립대학교산학협력단 | 살모넬라 검출을 위한 고리매개등온증폭법 기반 측방유동스트립 |
| WO2026074434A1 (en) * | 2024-10-01 | 2026-04-09 | Fondazione Istituto Italiano Di Tecnologia | Rad51/brca2 complex aptamers and uses thereof |
| CN119959532B (zh) * | 2025-01-03 | 2025-11-11 | 中国科学院精密测量科学与技术创新研究院 | 细胞色素c在制备elisa试剂盒方面的新用途 |
Family Cites Families (137)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4551435A (en) | 1983-08-24 | 1985-11-05 | Immunicon, Inc. | Selective removal of immunospecifically recognizable substances from solution |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| US4795698A (en) | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
| US4925788A (en) | 1986-10-24 | 1990-05-15 | Immunicon Corporation | Immunoassay system and procedure based on precipitin-like interaction between immune complex and Clq or other non-immunospecific factor |
| US5158871A (en) | 1988-02-12 | 1992-10-27 | University Of Connecticut | Method of using magnetic particles for isolating, collecting and assaying diagnostic ligates |
| US5108933A (en) | 1988-09-16 | 1992-04-28 | Immunicon Corporation | Manipulation of colloids for facilitating magnetic separations |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| SE470347B (sv) | 1990-05-10 | 1994-01-31 | Pharmacia Lkb Biotech | Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system |
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| US5861254A (en) | 1997-01-31 | 1999-01-19 | Nexstar Pharmaceuticals, Inc. | Flow cell SELEX |
| US5648214A (en) | 1990-06-11 | 1997-07-15 | University Research Corporation | High-affinity oligonucleotide ligands to the tachykinin substance P |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US5683867A (en) | 1990-06-11 | 1997-11-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: blended SELEX |
| ATE318832T1 (de) | 1990-06-11 | 2006-03-15 | Gilead Sciences Inc | Verfahren zur vervendung von nukleinsäureliganden |
| US5705337A (en) | 1990-06-11 | 1998-01-06 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chemi-SELEX |
| US5707796A (en) | 1990-06-11 | 1998-01-13 | Nexstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
| US5637459A (en) | 1990-06-11 | 1997-06-10 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chimeric selex |
| US5763177A (en) | 1990-06-11 | 1998-06-09 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex |
| US5496938A (en) | 1990-06-11 | 1996-03-05 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to HIV-RT and HIV-1 rev |
| US5580737A (en) | 1990-06-11 | 1996-12-03 | Nexstar Pharmaceuticals, Inc. | High-affinity nucleic acid ligands that discriminate between theophylline and caffeine |
| US5200084A (en) | 1990-09-26 | 1993-04-06 | Immunicon Corporation | Apparatus and methods for magnetic separation |
| AU649074B2 (en) | 1990-10-12 | 1994-05-12 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Modified ribozymes |
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| US5186827A (en) | 1991-03-25 | 1993-02-16 | Immunicon Corporation | Apparatus for magnetic separation featuring external magnetic means |
| US5541061A (en) | 1992-04-29 | 1996-07-30 | Affymax Technologies N.V. | Methods for screening factorial chemical libraries |
| US5817635A (en) | 1993-08-09 | 1998-10-06 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Modified ribozymes |
| US5736330A (en) | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
| US5612473A (en) | 1996-01-16 | 1997-03-18 | Gull Laboratories | Methods, kits and solutions for preparing sample material for nucleic acid amplification |
| US6051698A (en) | 1997-06-06 | 2000-04-18 | Janjic; Nebojsa | Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes |
| DE69735292T2 (de) | 1996-10-25 | 2006-10-19 | Gilead Sciences, Inc., Foster City | Gefaesszellen wachstumsfaktor (vegf) nukleinsäureligand-komplexe |
| US6632526B1 (en) | 1997-10-14 | 2003-10-14 | Luminex Corporation | Precision fluorescently dyed particles and methods of making and using same |
| US6719868B1 (en) | 1998-03-23 | 2004-04-13 | President And Fellows Of Harvard College | Methods for fabricating microfluidic structures |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| ATE261760T1 (de) | 1998-12-04 | 2004-04-15 | Orbital Biosciences L L C | Ultrafiltrations-vorrichtung und verfahren zu deren herstellung |
| US6623526B1 (en) | 1999-01-08 | 2003-09-23 | Corin Limited | Knee prosthesis |
| FR2788780B1 (fr) | 1999-01-27 | 2001-03-30 | Ap Cells Inc | Procede de preparation de vesicules membranaires |
| US6811668B1 (en) | 1999-06-22 | 2004-11-02 | Caliper Life Sciences, Inc. | Apparatus for the operation of a microfluidic device |
| US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
| CN100402850C (zh) | 1999-06-28 | 2008-07-16 | 加利福尼亚技术学院 | 微型制造的弹性体的阀和泵系统 |
| US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US7195670B2 (en) | 2000-06-27 | 2007-03-27 | California Institute Of Technology | High throughput screening of crystallization of materials |
| US6929030B2 (en) | 1999-06-28 | 2005-08-16 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US7144616B1 (en) | 1999-06-28 | 2006-12-05 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| AUPQ147799A0 (en) | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
| US20030204075A9 (en) * | 1999-08-09 | 2003-10-30 | The Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
| GB9927320D0 (en) | 1999-11-18 | 2000-01-12 | Chiron Spa | Exosome separation |
| WO2001051918A1 (en) | 2000-01-12 | 2001-07-19 | Ut-Battelle, Llc | A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream |
| US7452713B2 (en) | 2000-02-29 | 2008-11-18 | Stmicroelectronics S.R.L. | Process for manufacturing a microfluidic device with buried channels |
| US7867763B2 (en) | 2004-01-25 | 2011-01-11 | Fluidigm Corporation | Integrated chip carriers with thermocycler interfaces and methods of using the same |
| WO2001078087A2 (en) | 2000-04-06 | 2001-10-18 | Luminex Corporation | Magnetically-responsive microspheres |
| US6812023B1 (en) | 2000-04-27 | 2004-11-02 | Anosys, Inc. | Methods of producing membrane vesicles |
| US6645432B1 (en) | 2000-05-25 | 2003-11-11 | President & Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
| WO2002016904A2 (en) | 2000-08-23 | 2002-02-28 | Imego Ab | Microfluidic device and method with transport of magnetic particles into and out of wells |
| US20020048534A1 (en) | 2000-08-24 | 2002-04-25 | David Storek | Sample preparing arrangement and a method relating to such an arrangement |
| US6822454B2 (en) | 2000-12-01 | 2004-11-23 | Protasis Corporation | Microfluidic device with multiple microcoil NMR detectors and field gradient focusing |
| US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
| US6802342B2 (en) | 2001-04-06 | 2004-10-12 | Fluidigm Corporation | Microfabricated fluidic circuit elements and applications |
| WO2002099077A2 (en) | 2001-06-06 | 2002-12-12 | Proteologics, Inc. | Methods and compositions related to tagging of membrane surface proteins |
| US7390463B2 (en) | 2001-09-07 | 2008-06-24 | Corning Incorporated | Microcolumn-based, high-throughput microfluidic device |
| DE60237289D1 (de) | 2001-09-17 | 2010-09-23 | Gyros Patent Ab | Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit |
| US7189580B2 (en) | 2001-10-19 | 2007-03-13 | Wisconsin Alumni Research Foundation | Method of pumping fluid through a microfluidic device |
| US7253003B2 (en) | 2001-10-19 | 2007-08-07 | Wisconsin Alumni Research Foundation | Method for monitoring the environment within a microfluidic device |
| EP1463796B1 (en) | 2001-11-30 | 2013-01-09 | Fluidigm Corporation | Microfluidic device and methods of using same |
| US7691333B2 (en) | 2001-11-30 | 2010-04-06 | Fluidigm Corporation | Microfluidic device and methods of using same |
| AU2002360499A1 (en) | 2001-12-05 | 2003-06-17 | University Of Washington | Microfluidic device and surface decoration process for solid phase affinity binding assays |
| US7238255B2 (en) | 2001-12-31 | 2007-07-03 | Gyros Patent Ab | Microfluidic device and its manufacture |
| US6958119B2 (en) | 2002-02-26 | 2005-10-25 | Agilent Technologies, Inc. | Mobile phase gradient generation microfluidic device |
| US7195986B1 (en) | 2002-03-08 | 2007-03-27 | Caliper Life Sciences, Inc. | Microfluidic device with controlled substrate conductivity |
| GB2388189B (en) | 2002-04-29 | 2006-01-11 | Robert Jeffrey Geddes Carr | Optical detection and analysis of particles |
| US7189581B2 (en) | 2002-04-30 | 2007-03-13 | Wisconsin Alumni Research Foundation | Method of obtaining a sample concentration of a solution in a microfluidic device |
| EP1362827B1 (en) | 2002-05-16 | 2008-09-03 | Micronit Microfluidics B.V. | Method of fabrication of a microfluidic device |
| WO2004007582A2 (en) | 2002-07-15 | 2004-01-22 | University Of Virginia Patent Foundation | Hybrid polymers for functional tuning of microfluidic device surfaces |
| US7135147B2 (en) | 2002-07-26 | 2006-11-14 | Applera Corporation | Closing blade for deformable valve in a microfluidic device and method |
| US7201881B2 (en) | 2002-07-26 | 2007-04-10 | Applera Corporation | Actuator for deformable valves in a microfluidic device, and method |
| US7452509B2 (en) | 2002-07-26 | 2008-11-18 | Applied Biosystems Inc. | Microfluidic device including displaceable material trap, and system |
| KR100480338B1 (ko) | 2002-08-08 | 2005-03-30 | 한국전자통신연구원 | 극소량의 유체제어를 위한 미세 유체제어소자 |
| TW536524B (en) | 2002-09-17 | 2003-06-11 | Fan-Gen Tzeng | Network-type micro-channel device for micro-fluid |
| US7118661B2 (en) | 2002-09-30 | 2006-10-10 | The Regents Of The University Of California | Nanolaminate microfluidic device for mobility selection of particles |
| EP2719756B1 (en) | 2002-10-04 | 2017-04-05 | The Regents of the University of California | Microfluidic multi-compartment device for neuroscience research |
| FR2848125B1 (fr) | 2002-12-04 | 2006-06-09 | Commissariat Energie Atomique | Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee |
| US7467928B2 (en) | 2002-12-12 | 2008-12-23 | Board Of Trustees Of The University Of Arkansas | Microfluidic device utilizing magnetohydrodynamics and method for fabrication thereof |
| US7125711B2 (en) | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
| US7338637B2 (en) | 2003-01-31 | 2008-03-04 | Hewlett-Packard Development Company, L.P. | Microfluidic device with thin-film electronic devices |
| US7413709B2 (en) | 2003-02-12 | 2008-08-19 | Agilent Technologies, Inc. | PAEK-based microfluidic device with integrated electrospray emitter |
| JP3856763B2 (ja) | 2003-03-11 | 2006-12-13 | 財団法人川村理化学研究所 | マイクロ流体素子の製造方法 |
| US7604965B2 (en) | 2003-04-03 | 2009-10-20 | Fluidigm Corporation | Thermal reaction device and method for using the same |
| US7476363B2 (en) | 2003-04-03 | 2009-01-13 | Fluidigm Corporation | Microfluidic devices and methods of using same |
| EP1615721B1 (en) | 2003-04-03 | 2014-06-18 | Fluidigm Corporation | Microfluidic devices and methods of using same |
| US20050145496A1 (en) | 2003-04-03 | 2005-07-07 | Federico Goodsaid | Thermal reaction device and method for using the same |
| US7422725B2 (en) | 2003-05-01 | 2008-09-09 | Enplas Corporation | Sample handling unit applicable to microchip, and microfluidic device having microchips |
| US7544506B2 (en) | 2003-06-06 | 2009-06-09 | Micronics, Inc. | System and method for heating, cooling and heat cycling on microfluidic device |
| FR2862007B1 (fr) | 2003-11-12 | 2005-12-23 | Commissariat Energie Atomique | Dispositif microfluidique muni d'un nez d'electronebulisation. |
| US7329391B2 (en) | 2003-12-08 | 2008-02-12 | Applera Corporation | Microfluidic device and material manipulating method using same |
| EP1547688A1 (en) | 2003-12-23 | 2005-06-29 | STMicroelectronics S.r.l. | Microfluidic device and method of locally concentrating electrically charged substances in a microfluidic device |
| US7099778B2 (en) | 2003-12-30 | 2006-08-29 | Caliper Life Sciences, Inc. | Method for determining diffusivity and molecular weight in a microfluidic device |
| US7351380B2 (en) | 2004-01-08 | 2008-04-01 | Sandia Corporation | Microfluidic structures and methods for integrating a functional component into a microfluidic device |
| CA2554240A1 (en) | 2004-01-25 | 2005-08-11 | Fluidigm Corporation | Crystal forming devices and systems and methods for making and using the same |
| US7402229B2 (en) | 2004-03-31 | 2008-07-22 | Intel Corporation | Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device |
| US7575722B2 (en) | 2004-04-02 | 2009-08-18 | Eksigent Technologies, Inc. | Microfluidic device |
| US7419639B2 (en) | 2004-05-12 | 2008-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Multilayer microfluidic device |
| WO2005121864A2 (en) | 2004-06-07 | 2005-12-22 | Fluidigm Corporation | Optical lens system and method for microfluidic devices |
| JP2008523354A (ja) | 2004-11-17 | 2008-07-03 | ルミネックス・コーポレーション | フロー・アナライザからデータを管理するための装置と方法 |
| US7488596B2 (en) | 2004-12-17 | 2009-02-10 | Samsung Electronics Co., Ltd. | Microfluidic device comprising electrolysis device for cell lysis and method for electrochemically lysing cells using the same |
| CN101663576B (zh) | 2005-04-12 | 2012-05-23 | 卡钳生命科学股份有限公司 | 用于微流体器件的紧凑型光检测系统 |
| KR100590581B1 (ko) | 2005-05-10 | 2006-06-19 | 삼성전자주식회사 | 미세유동장치 및 그 제조방법 |
| JP4992201B2 (ja) | 2005-06-07 | 2012-08-08 | 富士ゼロックス株式会社 | マイクロ流体制御方法、マイクロ流体素子およびその製造方法 |
| TWI274040B (en) | 2005-12-23 | 2007-02-21 | Ind Tech Res Inst | Microfluidic device and method of manufacturing the same |
| US7568399B2 (en) | 2006-01-05 | 2009-08-04 | Integrated Sensing Systems, Inc. | Microfluidic device |
| US7581429B2 (en) | 2006-01-06 | 2009-09-01 | Integrated Sensing Systems, Inc. | Microfluidic device and method of operation |
| US8124015B2 (en) | 2006-02-03 | 2012-02-28 | Institute For Systems Biology | Multiplexed, microfluidic molecular assay device and assay method |
| ES2880460T3 (es) | 2006-03-09 | 2021-11-24 | Aethlon Medical Inc | Eliminación extracorpórea de partículas microvesiculares |
| EP2099930B1 (en) | 2006-12-13 | 2015-02-18 | Luminex Corporation | Systems and methods for multiplex analysis of pcr in real time |
| US8008019B2 (en) | 2007-11-28 | 2011-08-30 | Luminex Molecular Diagnostics | Use of dual-tags for the evaluation of genomic variable repeat regions |
| US9193968B2 (en) * | 2008-03-12 | 2015-11-24 | Aptamatrix, Inc. | Library compositions and methods for acyclic identification of aptamers |
| JP2012507300A (ja) * | 2008-10-30 | 2012-03-29 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | Ｒｎａパターンを評価する方法 |
| EP2350320A4 (en) * | 2008-11-12 | 2012-11-14 | Caris Life Sciences Luxembourg Holdings | METHOD AND SYSTEMS FOR USE OF EXOSOMES FOR THE DETERMINATION OF PHENOTYPES |
| WO2010065765A2 (en) | 2008-12-04 | 2010-06-10 | Aethlon Medical, Inc. | Affinity capture of circulating biomarkers |
| EP2202522A1 (en) | 2008-12-23 | 2010-06-30 | Universiteit Leiden | Methods for immobilizing microvesicles, means and methods for detecting them, and uses thereof |
| IL313131A (en) | 2009-02-11 | 2024-07-01 | Caris Mpi Inc | Molecular characterization of tumors |
| WO2010141862A2 (en) | 2009-06-05 | 2010-12-09 | Mayo Foundation For Medical Education And Research | Methods and materials for isolating exosomes |
| CA2779223A1 (en) | 2009-10-27 | 2011-05-12 | Caris Mpi, Inc. | Molecular profiling for personalized medicine |
| CA2782284A1 (en) * | 2009-11-30 | 2011-06-03 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems for isolating, storing, and analyzing vesicles |
| EP2524059A4 (en) * | 2010-01-13 | 2013-11-20 | Caris Life Sciences Luxembourg Holdings | DETECTION OF GASTROINTESTINAL DISEASES |
| WO2011106376A2 (en) * | 2010-02-23 | 2011-09-01 | The General Hospital Corporation | Use of microvesicles in the treatment of medical conditions |
| AU2011223789A1 (en) * | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| EP2721179A4 (en) | 2011-06-16 | 2014-10-01 | Caris Life Sciences Luxembourg Holdings S A R L | BIOMARKER COMPOSITIONS AND METHOD THEREFOR |
| CN103874770A (zh) * | 2011-08-08 | 2014-06-18 | 卡里斯生命科学卢森堡控股有限责任公司 | 生物标志物组合物和方法 |
| CA2892490A1 (en) | 2012-11-26 | 2014-05-30 | Caris Science, Inc. | Biomarker compositions and methods |
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2014
- 2014-08-28 BR BR112016004153A patent/BR112016004153A2/pt not_active IP Right Cessation
- 2014-08-28 CA CA2922689A patent/CA2922689A1/en not_active Abandoned
- 2014-08-28 CN CN201480063091.1A patent/CN105980615A/zh active Pending
- 2014-08-28 WO PCT/US2014/053306 patent/WO2015031694A2/en not_active Ceased
- 2014-08-28 EP EP14840036.9A patent/EP3039174B1/en active Active
- 2014-08-28 JP JP2016537869A patent/JP2016533752A/ja active Pending
- 2014-08-28 AU AU2014312211A patent/AU2014312211A1/en not_active Abandoned
- 2014-08-28 KR KR1020167007928A patent/KR20160080815A/ko not_active Ceased
- 2014-08-28 US US14/915,249 patent/US20160319361A1/en not_active Abandoned
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2019
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- 2019-09-26 IL IL26969319A patent/IL269693A/en unknown
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2020
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|---|---|
| CN105980615A (zh) | 2016-09-28 |
| JP2016533752A (ja) | 2016-11-04 |
| AU2014312211A1 (en) | 2016-03-10 |
| EP3039174A4 (en) | 2017-09-27 |
| US20160319361A1 (en) | 2016-11-03 |
| EP3039174A2 (en) | 2016-07-06 |
| CA2922689A1 (en) | 2015-03-05 |
| WO2015031694A2 (en) | 2015-03-05 |
| WO2015031694A3 (en) | 2015-06-04 |
| EP3039174B1 (en) | 2019-10-16 |
| KR20160080815A (ko) | 2016-07-08 |
| IL269693A (en) | 2019-11-28 |
| BR112016004153A2 (pt) | 2019-09-17 |
| US20210062270A1 (en) | 2021-03-04 |
| AU2019200115A1 (en) | 2019-01-31 |
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