IL240206A0 - Preparations containing amorphous sulfasalazine and their uses - Google Patents
Preparations containing amorphous sulfasalazine and their usesInfo
- Publication number
- IL240206A0 IL240206A0 IL240206A IL24020615A IL240206A0 IL 240206 A0 IL240206 A0 IL 240206A0 IL 240206 A IL240206 A IL 240206A IL 24020615 A IL24020615 A IL 24020615A IL 240206 A0 IL240206 A0 IL 240206A0
- Authority
- IL
- Israel
- Prior art keywords
- compositions
- amorphous sulfasalazine
- sulfasalazine
- amorphous
- Prior art date
Links
- UETNIIAIRMUTSM-UHFFFAOYSA-N Jacareubin Natural products CC1(C)OC2=CC3Oc4c(O)c(O)ccc4C(=O)C3C(=C2C=C1)O UETNIIAIRMUTSM-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 title 1
- 229960001940 sulfasalazine Drugs 0.000 title 1
- NCEXYHBECQHGNR-UHFFFAOYSA-N sulfasalazine Natural products C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361759933P | 2013-02-01 | 2013-02-01 | |
| US201361780340P | 2013-03-13 | 2013-03-13 | |
| PCT/US2014/014290 WO2014121137A2 (en) | 2013-02-01 | 2014-01-31 | Compositions and methods for the treatment of neurodegenerative and other diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL240206A0 true IL240206A0 (en) | 2015-09-24 |
Family
ID=50382538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL240206A IL240206A0 (en) | 2013-02-01 | 2015-07-29 | Preparations containing amorphous sulfasalazine and their uses |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US9597339B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2950797B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6328146B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20150139830A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105163735B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2014212109B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2899032A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2752021T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL240206A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014121137A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2752021T3 (es) * | 2013-02-01 | 2020-04-02 | Glialogix Inc | Composiciones y métodos para el tratamiento de enfermedades neurodegenerativas y otras enfermedades |
| KR102364840B1 (ko) * | 2014-11-05 | 2022-02-18 | 삼성전자주식회사 | 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법 |
| US20160199393A1 (en) * | 2015-01-08 | 2016-07-14 | China Medical University | Methods of treating brain ischemia or hypoxia |
| ES2650175B1 (es) * | 2016-04-15 | 2019-02-04 | Servicio Andaluz De Salud | Tratamiento de enfermedades neurodegenerativas |
| CN109414507A (zh) * | 2016-04-26 | 2019-03-01 | 美国圣路易斯大学 | 用于预防和治疗神经退行性疾病的高度选择性腺苷a3受体亚型激动剂 |
| US20180110760A1 (en) * | 2016-10-21 | 2018-04-26 | Glialogix, Inc. | Compositions and methods for the treatmentof neurodegenerative and other diseases |
| US10473672B2 (en) * | 2017-02-09 | 2019-11-12 | Kaohsiung Chang Gung Memorial Hospital | Methods for diagnosing and treating Alzheimers disease using G72 protein and SLC7A11 mRNA as biomarkers |
| RU2680844C1 (ru) * | 2017-10-12 | 2019-02-28 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Применение сульфасалазина в качестве ингибитора образования конечных продуктов гликирования |
| WO2019102992A1 (ja) * | 2017-11-21 | 2019-05-31 | 積水化学工業株式会社 | 皮膚外用剤 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2396145A (en) | 1940-12-14 | 1946-03-05 | Pharmscia Ab | Heterocyclic sulphonamido azo compounds |
| FR2608988B1 (fr) | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
| MX9702357A (es) | 1994-09-29 | 1997-06-28 | Andaris Ltd | Microparticulas secadas por aspersion como vehiculos terapeuticos. |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| ITMI962356A1 (it) | 1996-11-13 | 1998-05-13 | Uni Degli Studi Di Brescia D I | Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di |
| PT954282E (pt) | 1997-01-16 | 2005-06-30 | Massachusetts Inst Technology | Preparacao de particulas para inalacao |
| WO1999066903A2 (en) | 1998-06-24 | 1999-12-29 | Advanced Inhalation Research, Inc. | Large porous particles emitted from an inhaler |
| DE69936386T2 (de) | 1998-08-25 | 2008-03-06 | Advanced Inhalation Research, Inc., Cambridge | Sprühgetrocknete proteinformulierungen |
| US6586008B1 (en) | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| KR100417623B1 (ko) | 2000-03-28 | 2004-02-05 | 주식회사 뉴로테크 | 뇌질환 예방 및 치료용 조성물 |
| CA2307278A1 (en) | 2000-04-28 | 2001-10-28 | University Of British Columbia | Use of n-heterocyclic substituted salicylic acids for inhibition of cellular uptake of cystine |
| KR100664822B1 (ko) | 2002-02-01 | 2007-01-04 | 화이자 프로덕츠 인코포레이티드 | 변형된 분무-건조 장치를 이용한 균질한 분무-건조된 고체비결정성 약물 분산액의 제조 방법 |
| AU2003239463B2 (en) | 2002-02-01 | 2007-10-18 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| US20060045865A1 (en) | 2004-08-27 | 2006-03-02 | Spherics, Inc. | Controlled regional oral delivery |
| EP1824564A4 (en) | 2004-10-27 | 2009-09-16 | Uab Research Foundation | METHOD FOR TREATING GLIOM |
| CA2620389C (en) | 2005-08-31 | 2014-06-17 | Abraxis Bioscience, Llc | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
| US20070053869A1 (en) | 2005-09-02 | 2007-03-08 | Yuichi Sugiyama | Formulation and method for enhancement of gastrointestinal absorption of pharmaceutical agents |
| GB0602123D0 (en) * | 2006-02-02 | 2006-03-15 | Novartis Ag | Organic compounds |
| ES2672627T3 (es) | 2006-02-02 | 2018-06-15 | Novartis Ag | Tratamiento de la esclerosis tuberosa |
| US7964585B2 (en) | 2006-03-14 | 2011-06-21 | Case Western Reserve University | Composition and method of treating peripheral neuropathy |
| NZ575171A (en) | 2006-08-31 | 2012-04-27 | Aptalis Pharmatech Inc | Drug delivery systems comprising solid solutions of weakly basic drugs |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| CN101959504A (zh) * | 2008-02-28 | 2011-01-26 | 比艾尔-坡特拉有限公司 | 用于难溶性药物的药物组合物 |
| PT2113254E (pt) * | 2008-04-28 | 2012-11-26 | Txcell | Composições para o tratamento de um estado inflamatório auto-imune |
| TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
| EP3130396B1 (en) | 2009-03-27 | 2021-03-17 | Bend Research, Inc. | Spray-drying process |
| WO2012031129A2 (en) | 2010-09-03 | 2012-03-08 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
| US9084944B2 (en) | 2010-09-03 | 2015-07-21 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
| HK1204970A1 (en) | 2012-01-31 | 2015-12-11 | Cerulean Pharma Inc. | Polymer-agent conjugates, particles, compositions, and related methods of use |
| ES2752021T3 (es) * | 2013-02-01 | 2020-04-02 | Glialogix Inc | Composiciones y métodos para el tratamiento de enfermedades neurodegenerativas y otras enfermedades |
| WO2015103230A1 (en) | 2013-12-31 | 2015-07-09 | Ascendia Pharmaceuticals, Llc | Pharmaceutical compositions for poorly water-soluble compounds |
-
2014
- 2014-01-31 ES ES14712798T patent/ES2752021T3/es active Active
- 2014-01-31 US US14/170,405 patent/US9597339B2/en not_active Expired - Fee Related
- 2014-01-31 JP JP2015556185A patent/JP6328146B2/ja not_active Expired - Fee Related
- 2014-01-31 CA CA2899032A patent/CA2899032A1/en not_active Abandoned
- 2014-01-31 WO PCT/US2014/014290 patent/WO2014121137A2/en not_active Ceased
- 2014-01-31 CN CN201480019892.8A patent/CN105163735B/zh not_active Expired - Fee Related
- 2014-01-31 AU AU2014212109A patent/AU2014212109B2/en not_active Ceased
- 2014-01-31 KR KR1020157023718A patent/KR20150139830A/ko not_active Withdrawn
- 2014-01-31 EP EP14712798.9A patent/EP2950797B1/en active Active
-
2015
- 2015-07-29 IL IL240206A patent/IL240206A0/en unknown
-
2016
- 2016-11-30 US US15/365,843 patent/US9980978B2/en not_active Expired - Fee Related
- 2016-11-30 US US15/365,835 patent/US9974798B2/en not_active Expired - Fee Related
-
2017
- 2017-02-10 US US15/430,294 patent/US9918997B2/en not_active Expired - Fee Related
-
2018
- 2018-04-17 US US15/955,020 patent/US10398713B2/en not_active Expired - Fee Related
- 2018-04-17 JP JP2018079284A patent/JP2018123159A/ja active Pending
- 2018-08-28 AU AU2018222921A patent/AU2018222921A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014121137A3 (en) | 2014-11-27 |
| KR20150139830A (ko) | 2015-12-14 |
| WO2014121137A2 (en) | 2014-08-07 |
| ES2752021T3 (es) | 2020-04-02 |
| EP2950797B1 (en) | 2019-09-11 |
| JP2016507526A (ja) | 2016-03-10 |
| AU2014212109A1 (en) | 2015-08-06 |
| CN105163735B (zh) | 2018-12-11 |
| JP2018123159A (ja) | 2018-08-09 |
| US20170079991A1 (en) | 2017-03-23 |
| US9974798B2 (en) | 2018-05-22 |
| US20140221321A1 (en) | 2014-08-07 |
| US9597339B2 (en) | 2017-03-21 |
| US9980978B2 (en) | 2018-05-29 |
| US20170165279A1 (en) | 2017-06-15 |
| AU2014212109B2 (en) | 2018-05-31 |
| US20190015431A1 (en) | 2019-01-17 |
| JP6328146B2 (ja) | 2018-05-23 |
| CA2899032A1 (en) | 2014-08-07 |
| CN105163735A (zh) | 2015-12-16 |
| US20170079990A1 (en) | 2017-03-23 |
| AU2018222921A1 (en) | 2018-09-20 |
| US10398713B2 (en) | 2019-09-03 |
| EP2950797A2 (en) | 2015-12-09 |
| US9918997B2 (en) | 2018-03-20 |
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