IL239096B - Methods for identifying high-throughput receptor ligands - Google Patents
Methods for identifying high-throughput receptor ligandsInfo
- Publication number
- IL239096B IL239096B IL239096A IL23909615A IL239096B IL 239096 B IL239096 B IL 239096B IL 239096 A IL239096 A IL 239096A IL 23909615 A IL23909615 A IL 23909615A IL 239096 B IL239096 B IL 239096B
- Authority
- IL
- Israel
- Prior art keywords
- methods
- high throughput
- ligand identification
- receptor
- throughput receptor
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/06—Methods of screening libraries by measuring effects on living organisms, tissues or cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261735791P | 2012-12-11 | 2012-12-11 | |
| US201361833588P | 2013-06-11 | 2013-06-11 | |
| PCT/US2013/073275 WO2014093118A1 (en) | 2012-12-11 | 2013-12-05 | Methods for high throughput receptor:ligand identification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL239096A0 IL239096A0 (en) | 2015-07-30 |
| IL239096B true IL239096B (en) | 2019-03-31 |
Family
ID=50934838
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL239096A IL239096B (en) | 2012-12-11 | 2015-05-31 | Methods for identifying high-throughput receptor ligands |
| IL262785A IL262785B (en) | 2012-12-11 | 2018-11-05 | Methods for identifying high-throughput receptor ligands |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL262785A IL262785B (en) | 2012-12-11 | 2018-11-05 | Methods for identifying high-throughput receptor ligands |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10048271B2 (enExample) |
| EP (2) | EP2931949B1 (enExample) |
| JP (2) | JP2016500255A (enExample) |
| KR (1) | KR102208505B1 (enExample) |
| CN (2) | CN105121715B (enExample) |
| AU (2) | AU2013359907B2 (enExample) |
| BR (1) | BR112015013557B1 (enExample) |
| CA (1) | CA2894511C (enExample) |
| IL (2) | IL239096B (enExample) |
| SG (2) | SG11201504558TA (enExample) |
| WO (1) | WO2014093118A1 (enExample) |
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| CN105121715B (zh) | 2012-12-11 | 2018-10-26 | 艾伯特叶史瓦大学爱因斯坦医学院 | 高通量受体:配体鉴定方法 |
| CA2954360C (en) * | 2014-07-07 | 2022-11-22 | Johan ELF | Phenotypic characterization and in situ genotyping of a library of genetically different cells |
| CN109475628A (zh) | 2016-05-18 | 2019-03-15 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
| CA3022331A1 (en) * | 2016-05-18 | 2017-11-23 | Albert Einstein College Of Medicine, Inc. | Variant pd-l1 polypeptides, t-cell modulatory multimeric polypeptides, and methods of use thereof |
| JP7019171B2 (ja) * | 2016-11-24 | 2022-02-15 | 国立研究開発法人物質・材料研究機構 | 細胞表面に存在する分子の結合による細胞間相互作用を計測する方法 |
| WO2018111941A1 (en) * | 2016-12-12 | 2018-06-21 | 13.8, Inc. | Compositions of high affinity reagents and methods of use thereof |
| AU2017379900B2 (en) | 2016-12-22 | 2024-12-05 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| WO2018129474A1 (en) | 2017-01-09 | 2018-07-12 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| EP3596118B1 (en) | 2017-03-15 | 2024-08-21 | Cue Biopharma, Inc. | Combination of multimeric fusion polypeptides and immune checkpoint inhibitor for treating hpv-associated cancer |
| WO2019051127A1 (en) | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | MULTIMER MODULATOR POLYPEPTIDE OF LYMPHOCYTE T HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| WO2019139896A1 (en) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| EP4143221A1 (en) * | 2020-04-30 | 2023-03-08 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Pd-l1 variants with improved affinity towards pd-1 |
| EP4149534A4 (en) | 2020-05-12 | 2024-09-04 | Cue Biopharma, Inc. | MULTIMERIC POLYPEPTIDES MODULATING T CELLS AND METHODS OF USE THEREOF |
| WO2022056014A1 (en) | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
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-
2013
- 2013-12-05 CN CN201380071758.8A patent/CN105121715B/zh not_active Expired - Fee Related
- 2013-12-05 AU AU2013359907A patent/AU2013359907B2/en not_active Ceased
- 2013-12-05 JP JP2015545835A patent/JP2016500255A/ja not_active Ceased
- 2013-12-05 CN CN201811139644.3A patent/CN109324190A/zh active Pending
- 2013-12-05 KR KR1020157017981A patent/KR102208505B1/ko not_active Expired - Fee Related
- 2013-12-05 SG SG11201504558TA patent/SG11201504558TA/en unknown
- 2013-12-05 EP EP13862361.6A patent/EP2931949B1/en active Active
- 2013-12-05 BR BR112015013557-9A patent/BR112015013557B1/pt not_active IP Right Cessation
- 2013-12-05 EP EP19197120.9A patent/EP3640375A3/en not_active Withdrawn
- 2013-12-05 SG SG10201808463RA patent/SG10201808463RA/en unknown
- 2013-12-05 CA CA2894511A patent/CA2894511C/en active Active
- 2013-12-05 US US14/649,176 patent/US10048271B2/en active Active
- 2013-12-05 WO PCT/US2013/073275 patent/WO2014093118A1/en not_active Ceased
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2015
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2018
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2019
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| CN105121715B (zh) | 2018-10-26 |
| US11226339B2 (en) | 2022-01-18 |
| US20160011204A1 (en) | 2016-01-14 |
| EP2931949A4 (en) | 2016-07-27 |
| HK1218144A1 (zh) | 2017-02-03 |
| SG10201808463RA (en) | 2018-11-29 |
| IL262785A (en) | 2018-12-31 |
| AU2018201812A1 (en) | 2018-04-05 |
| CA2894511A1 (en) | 2014-06-19 |
| JP2016500255A (ja) | 2016-01-12 |
| AU2013359907A1 (en) | 2015-06-18 |
| EP3640375A3 (en) | 2020-07-29 |
| CA2894511C (en) | 2021-12-07 |
| KR102208505B1 (ko) | 2021-01-27 |
| AU2018201812B2 (en) | 2020-09-10 |
| EP2931949B1 (en) | 2019-09-18 |
| JP7128792B2 (ja) | 2022-08-31 |
| EP3640375A2 (en) | 2020-04-22 |
| KR20150094674A (ko) | 2015-08-19 |
| JP2020043860A (ja) | 2020-03-26 |
| IL239096A0 (en) | 2015-07-30 |
| EP2931949A1 (en) | 2015-10-21 |
| BR112015013557A2 (pt) | 2020-01-14 |
| BR112015013557B1 (pt) | 2021-12-14 |
| IL262785B (en) | 2020-04-30 |
| SG11201504558TA (en) | 2015-07-30 |
| CN109324190A (zh) | 2019-02-12 |
| WO2014093118A1 (en) | 2014-06-19 |
| CN105121715A (zh) | 2015-12-02 |
| US10048271B2 (en) | 2018-08-14 |
| US20200011875A1 (en) | 2020-01-09 |
| AU2013359907B2 (en) | 2018-01-18 |
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