IL236524B - Camel antibody libraries - Google Patents

Camel antibody libraries

Info

Publication number
IL236524B
IL236524B IL236524A IL23652414A IL236524B IL 236524 B IL236524 B IL 236524B IL 236524 A IL236524 A IL 236524A IL 23652414 A IL23652414 A IL 23652414A IL 236524 B IL236524 B IL 236524B
Authority
IL
Israel
Prior art keywords
antibody libraries
camelid antibody
camelid
libraries
antibody
Prior art date
Application number
IL236524A
Other languages
English (en)
Hebrew (he)
Other versions
IL236524A0 (en
Inventor
Christophe Frederic Jerome Blanchetot
Haard Johannes Joseph Wilhelmus De
Alex Klarenbeek
Ikbel Achour
Mazouari Khalil El
Favero Jurgen Del
Original Assignee
Christophe Frederic Jerome Blanchetot
Haard Johannes Joseph Wilhelmus De
Alex Klarenbeek
Ikbel Achour
Mazouari Khalil El
Favero Jurgen Del
Argenx Bvba
Argenx Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christophe Frederic Jerome Blanchetot, Haard Johannes Joseph Wilhelmus De, Alex Klarenbeek, Ikbel Achour, Mazouari Khalil El, Favero Jurgen Del, Argenx Bvba, Argenx Se filed Critical Christophe Frederic Jerome Blanchetot
Publication of IL236524A0 publication Critical patent/IL236524A0/en
Publication of IL236524B publication Critical patent/IL236524B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
IL236524A 2012-08-31 2014-12-31 Camel antibody libraries IL236524B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261695819P 2012-08-31 2012-08-31
PCT/EP2013/068110 WO2014033304A2 (en) 2012-08-31 2013-09-02 Highly diverse combinatorial antibody libraries

Publications (2)

Publication Number Publication Date
IL236524A0 IL236524A0 (en) 2015-02-26
IL236524B true IL236524B (en) 2019-01-31

Family

ID=49117845

Family Applications (1)

Application Number Title Priority Date Filing Date
IL236524A IL236524B (en) 2012-08-31 2014-12-31 Camel antibody libraries

Country Status (9)

Country Link
US (1) US10040870B2 (enExample)
EP (1) EP2890709A2 (enExample)
JP (1) JP6283030B2 (enExample)
CN (1) CN104583236A (enExample)
AU (1) AU2013310839B2 (enExample)
CA (1) CA2879834A1 (enExample)
IL (1) IL236524B (enExample)
IN (1) IN2015DN00138A (enExample)
WO (1) WO2014033304A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9708412B2 (en) 2015-05-21 2017-07-18 Harpoon Therapeutics, Inc. Trispecific binding proteins and methods of use
WO2017201493A1 (en) 2016-05-20 2017-11-23 Harpoon Therapeutics, Inc. Single chain variable fragment cd3 binding proteins
EP3493844A4 (en) 2016-05-20 2021-03-24 Harpoon Therapeutics Inc. SINGLE DOMAIN SERUM ALBUMIN BINDING PROTEIN
US11623958B2 (en) 2016-05-20 2023-04-11 Harpoon Therapeutics, Inc. Single chain variable fragment CD3 binding proteins
WO2018007999A1 (en) 2016-07-08 2018-01-11 Staten Biotechnology B.V. Anti-apoc3 antibodies and methods of use thereof
AU2017363300A1 (en) 2016-11-23 2019-06-20 Harpoon Therapeutics, Inc. Prostate specific membrane antigen binding protein
WO2018098356A1 (en) * 2016-11-23 2018-05-31 Harpoon Therapeutics, Inc. Psma targeting trispecific proteins and methods of use
WO2018103093A1 (zh) * 2016-12-09 2018-06-14 深圳华大基因研究院 骆驼科抗体可变区免疫组库构建的引物组合及应用
US11535668B2 (en) 2017-02-28 2022-12-27 Harpoon Therapeutics, Inc. Inducible monovalent antigen binding protein
CN110506056A (zh) 2017-04-21 2019-11-26 斯塔滕生物技术有限公司 抗apoc3抗体和其使用方法
WO2018209304A1 (en) 2017-05-12 2018-11-15 Harpoon Therapeutics, Inc. Msln targeting trispecific proteins and methods of use
EP3621994A4 (en) 2017-05-12 2020-12-30 Harpoon Therapeutics, Inc. MESOTHELIN BINDING PROTEINS
MX2020003915A (es) 2017-10-13 2020-10-08 Harpoon Therapeutics Inc Proteinas trispecificas y metodos de uso.
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
PE20210119A1 (es) 2017-10-31 2021-01-19 Staten Biotechnology B V Anticuerpos anti-apoc3 y metodos de uso de estos
BR112020023330A2 (pt) 2018-05-14 2021-04-20 Harpoon Therapeutics, Inc. porção de ligação para ativação condicional de moléculas de imunoglobulina
US12195544B2 (en) 2018-09-21 2025-01-14 Harpoon Therapeutics, Inc. EGFR binding proteins and methods of use
US10815311B2 (en) 2018-09-25 2020-10-27 Harpoon Therapeutics, Inc. DLL3 binding proteins and methods of use
AU2020275002A1 (en) 2019-05-14 2021-12-23 Harpoon Therapeutics, Inc. EpCAM binding proteins and methods of use
CN115768463A (zh) 2020-02-21 2023-03-07 哈普恩治疗公司 Flt3结合蛋白及使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
US8444976B2 (en) * 2008-07-02 2013-05-21 Argen-X B.V. Antigen binding polypeptides
GB2461546B (en) * 2008-07-02 2010-07-07 Argen X Bv Antigen binding polypeptides
CN102459591B (zh) * 2009-05-20 2015-05-13 诺维莫尼公司 合成性的多肽文库以及用于建立具有天然多样性的多肽变体的方法
GB2476681B (en) 2010-01-04 2012-04-04 Argen X Bv Humanized camelid VH, VK and VL immunoglobulin domains

Also Published As

Publication number Publication date
CN104583236A (zh) 2015-04-29
AU2013310839B2 (en) 2017-06-01
IN2015DN00138A (enExample) 2015-06-12
WO2014033304A2 (en) 2014-03-06
JP6283030B2 (ja) 2018-02-21
IL236524A0 (en) 2015-02-26
JP2015526495A (ja) 2015-09-10
WO2014033304A3 (en) 2014-05-01
AU2013310839A1 (en) 2015-01-29
CA2879834A1 (en) 2014-03-06
US20150166680A1 (en) 2015-06-18
EP2890709A2 (en) 2015-07-08
US10040870B2 (en) 2018-08-07

Similar Documents

Publication Publication Date Title
IL264558A (en) Anti–il–23p19 antibodies
IL236524B (en) Camel antibody libraries
IL259826A (en) Anti-alphabetatisiar antibody
ZA201407509B (en) Anti-fcrn antibodies
IL234942A0 (en) A tau antibody of human origin
ZA201407897B (en) Protease-regulated antibodies
PL2703486T3 (pl) Przeciwciało anty-b7-h3
ZA201409358B (en) Anti-siglec- 15 antibodies
ZA201407316B (en) Anti-fgfr2 antibody
SG10201709290XA (en) Anti-H7cr Antibodies
ZA201407079B (en) Cdr-modified anti-siglec-15 antibody
TWI563004B (en) Anti-hxcr1 antibody
GB201220242D0 (en) Antibody
EP2804876A4 (en) NEW ANTIBODIES
EP2811018A4 (en) ANTI-BODY ANTI-sAPPß
IL235188A0 (en) Antibodies against c-pdgf
GB201209584D0 (en) Modified antibodies

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed