IL234710A - Antibodies that neutralize rsv, mpv and pvm and uses thereof - Google Patents
Antibodies that neutralize rsv, mpv and pvm and uses thereofInfo
- Publication number
- IL234710A IL234710A IL234710A IL23471014A IL234710A IL 234710 A IL234710 A IL 234710A IL 234710 A IL234710 A IL 234710A IL 23471014 A IL23471014 A IL 23471014A IL 234710 A IL234710 A IL 234710A
- Authority
- IL
- Israel
- Prior art keywords
- pvm
- rsv
- antibodies
- mpv
- neutralize
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pulmonology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261613197P | 2012-03-20 | 2012-03-20 | |
| US201261655310P | 2012-06-04 | 2012-06-04 | |
| PCT/IB2013/000627 WO2013140247A1 (en) | 2012-03-20 | 2013-03-14 | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL234710A true IL234710A (en) | 2016-12-29 |
Family
ID=48471031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL234710A IL234710A (en) | 2012-03-20 | 2014-09-17 | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US9498531B2 (https=) |
| EP (1) | EP2828293B1 (https=) |
| JP (4) | JP6445423B2 (https=) |
| KR (1) | KR102149069B1 (https=) |
| CN (2) | CN104350069B (https=) |
| AU (1) | AU2013237087B2 (https=) |
| BR (1) | BR112014023063A2 (https=) |
| CA (1) | CA2865856C (https=) |
| DK (1) | DK2828293T3 (https=) |
| EA (1) | EA030319B1 (https=) |
| ES (1) | ES2657470T3 (https=) |
| IL (1) | IL234710A (https=) |
| IN (1) | IN2014DN07299A (https=) |
| NZ (1) | NZ630920A (https=) |
| PL (1) | PL2828293T3 (https=) |
| WO (1) | WO2013140247A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ630920A (en) * | 2012-03-20 | 2017-01-27 | Humabs Biomed Sa | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
| WO2014115893A1 (ja) | 2013-01-28 | 2014-07-31 | 株式会社イーベック | ヒト・メタニューモウイルスに特異的なヒト抗体もしくはその抗原結合性断片 |
| TWI659968B (zh) | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒ｆ蛋白質的人類抗體及其使用方法 |
| WO2020160171A1 (en) * | 2019-01-29 | 2020-08-06 | Sanford Burnham Prebys Medical Discovery Institute | Topically formulated antibody compositions for reducing pathogen transmission and methods of using same |
| CN114174331B (zh) * | 2019-05-21 | 2024-06-04 | 佐治亚大学研究基金会有限公司 | 结合人类偏肺病毒融合蛋白的抗体及其用途 |
| CN117136197A (zh) * | 2021-02-09 | 2023-11-28 | 胡默波斯生物医学公司 | 抗呼吸道合胞病毒、人偏肺病毒和小鼠肺炎病毒的抗体和其使用方法 |
| US20240150444A1 (en) * | 2021-02-26 | 2024-05-09 | Fred Hutchinson Cancer Center | Protective antibodies against respiratory viral infections |
| CN115466326B (zh) * | 2021-06-11 | 2024-06-04 | 中国科学院微生物研究所 | 一种呼吸道合胞病毒的人源单克隆抗体及其应用 |
| AU2022404234A1 (en) * | 2021-12-06 | 2024-05-09 | Xiamen University | Antibody for recognizing rsv pre-f protein and use thereof |
| WO2025015321A1 (en) * | 2023-07-13 | 2025-01-16 | Vir Biotechnology, Inc. | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3766162A (en) | 1971-08-24 | 1973-10-16 | Hoffmann La Roche | Barbituric acid antigens and antibodies specific therefor |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4233402A (en) | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
| JPS5896026A (ja) | 1981-10-30 | 1983-06-07 | Nippon Chemiphar Co Ltd | 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤 |
| EP0098110B1 (en) | 1982-06-24 | 1989-10-18 | NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA also known as JAPAN CHEMICAL RESEARCH CO., LTD | Long-acting composition |
| US4766106A (en) | 1985-06-26 | 1988-08-23 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polymer conjugation |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US4831175A (en) | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
| US5595721A (en) | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| MY133346A (en) | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
| US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
| CA2435180C (en) | 2001-01-19 | 2019-04-09 | Vironovative B.V. | A virus causing respiratory tract illness in susceptible mammals |
| EP1532175B1 (en) | 2002-03-22 | 2012-10-17 | Aprogen, Inc. | Humanized antibody and process for preparing the same |
| WO2004010935A2 (en) | 2002-07-25 | 2004-02-05 | Medimmune, Inc. | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
| WO2004076677A2 (en) | 2003-02-26 | 2004-09-10 | Institute For Research In Biomedicine | Monoclonal antibody production by ebv transformation of b cells |
| WO2004092207A2 (en) * | 2003-04-16 | 2004-10-28 | Algonomics N.V. | Respiratory syncytial virus (rsv) peptides |
| EP1473037A1 (en) | 2003-05-02 | 2004-11-03 | Vironovative B.V. | Treatment of hPMV infections with Ribavirin |
| CA2603940A1 (en) * | 2005-04-08 | 2006-10-19 | Nancy Ulbrandt | Antibodies against mammalian metapneumovirus |
| EP1997830A1 (en) * | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| BRPI0914092B1 (pt) | 2008-10-22 | 2021-08-31 | Institute For Research In Biomedicine | Método de produção de um anticorpo a partir de células plasmáticas, método de produção de um anticorpo monoclonal a partir de células plasmáticas e método de produção de um anticorpo ou de um fragmento de anticorpo |
| AU2010264686A1 (en) * | 2009-06-24 | 2012-01-19 | Glaxosmithkline Biologicals S.A. | Vaccine |
| PL2464664T3 (pl) * | 2009-08-13 | 2016-02-29 | Crucell Holland Bv | Przeciwciała przeciwko ludzkiemu syncytialnemu wirusowi oddechowemu (RSV) i sposoby zastosowania |
| PH12012502244A1 (en) * | 2010-07-09 | 2016-09-30 | Crucell Holland Bv | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| NZ630920A (en) * | 2012-03-20 | 2017-01-27 | Humabs Biomed Sa | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
-
2013
- 2013-03-14 NZ NZ630920A patent/NZ630920A/en not_active IP Right Cessation
- 2013-03-14 AU AU2013237087A patent/AU2013237087B2/en not_active Ceased
- 2013-03-14 BR BR112014023063A patent/BR112014023063A2/pt active Search and Examination
- 2013-03-14 DK DK13724357.2T patent/DK2828293T3/en active
- 2013-03-14 EP EP13724357.2A patent/EP2828293B1/en active Active
- 2013-03-14 CA CA2865856A patent/CA2865856C/en active Active
- 2013-03-14 US US13/827,845 patent/US9498531B2/en active Active
- 2013-03-14 WO PCT/IB2013/000627 patent/WO2013140247A1/en not_active Ceased
- 2013-03-14 KR KR1020147029324A patent/KR102149069B1/ko not_active Expired - Fee Related
- 2013-03-14 JP JP2015501002A patent/JP6445423B2/ja active Active
- 2013-03-14 PL PL13724357T patent/PL2828293T3/pl unknown
- 2013-03-14 CN CN201380026218.8A patent/CN104350069B/zh active Active
- 2013-03-14 EA EA201491724A patent/EA030319B1/ru unknown
- 2013-03-14 ES ES13724357.2T patent/ES2657470T3/es active Active
- 2013-03-14 CN CN201711120146.XA patent/CN107880121B/zh not_active Expired - Fee Related
-
2014
- 2014-08-29 IN IN7299DEN2014 patent/IN2014DN07299A/en unknown
- 2014-09-17 IL IL234710A patent/IL234710A/en active IP Right Grant
-
2016
- 2016-08-10 US US15/233,026 patent/US10072071B2/en active Active
-
2018
- 2018-08-09 US US16/059,408 patent/US20190153073A1/en not_active Abandoned
- 2018-11-29 JP JP2018224174A patent/JP6722264B2/ja not_active Expired - Fee Related
-
2020
- 2020-05-27 US US16/885,009 patent/US11421020B2/en active Active
- 2020-06-19 JP JP2020106004A patent/JP7069251B2/ja not_active Expired - Fee Related
-
2022
- 2022-05-02 JP JP2022076023A patent/JP2022132244A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUS2400016I1 (hu) | FCRN elleni antitestek | |
| IL293362B1 (en) | Broadly-neutralizing anti-hiv antibodies | |
| IL234710A (en) | Antibodies that neutralize rsv, mpv and pvm and uses thereof | |
| IL243752A0 (en) | Multispecific antibodies, compositions comprising same and uses thereof | |
| BR112014030278A2 (pt) | anticorpo, e, composição. | |
| CL2016000680A1 (es) | Formulaciones de anticuerpos anti-pdl1. | |
| BR112015011903A2 (pt) | dispositivo de rastreamento. | |
| BR112013024256A2 (pt) | veículo. | |
| EP3022544A4 (en) | Microfluidic chip | |
| BR302013000148S1 (pt) | Configuração aplicada em estojo de utensílios. | |
| IL238227A0 (en) | Anti-c16orf54 antibodies and methods of use thereof | |
| HRP20181874T1 (hr) | Anti-cxcr3 protutijela | |
| ITTO20130153A1 (it) | Veicolo elettrico. | |
| EP2817737A4 (en) | ADAPTIVE SYSTEM | |
| LT2814843T (lt) | ŽMOGAUS MONOKLONINIAI ANTIKŪNAI, NEUTRALIZUOJANTYS IL-1ß | |
| BR112014026126A2 (pt) | veículo anfíbio. | |
| FR2986872B1 (fr) | . | |
| ITMI20120314U1 (it) | Custodia di protezione in pelle. | |
| BR112014027148A2 (pt) | reservatório de veículo automotivo, e, veiculo automotivo | |
| CL2016001315A1 (es) | Separador. | |
| ITTO20110824A1 (it) | Veicolo di piccole dimensioni. | |
| EP2900693A4 (en) | ADCC-mediating antibodies, combinations and uses thereof | |
| BR112014027645A2 (pt) | 5-halogenopirazol bifenilcarboxamidas. | |
| ES1078792Y (es) | Unidad de oficina - comisaría móvil. | |
| FR3010651B1 (fr) | Module de poinconnage |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |