IL23206A - Process for the manufacture of 7-nitro-3h-1,4-benzodiazepin-2(1h)-one - Google Patents

Process for the manufacture of 7-nitro-3h-1,4-benzodiazepin-2(1h)-one

Info

Publication number
IL23206A
IL23206A IL23206A IL2320665A IL23206A IL 23206 A IL23206 A IL 23206A IL 23206 A IL23206 A IL 23206A IL 2320665 A IL2320665 A IL 2320665A IL 23206 A IL23206 A IL 23206A
Authority
IL
Israel
Prior art keywords
benzodiazepin
nitro
manufacture
Prior art date
Application number
IL23206A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL23206A publication Critical patent/IL23206A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL23206A 1964-04-17 1965-03-24 Process for the manufacture of 7-nitro-3h-1,4-benzodiazepin-2(1h)-one IL23206A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US360755A US3335181A (en) 1964-04-17 1964-04-17 Ammonolysis of 2-halo-2'-benzoyl-4'-nitroacetanilides

Publications (1)

Publication Number Publication Date
IL23206A true IL23206A (en) 1968-07-25

Family

ID=23419290

Family Applications (1)

Application Number Title Priority Date Filing Date
IL23206A IL23206A (en) 1964-04-17 1965-03-24 Process for the manufacture of 7-nitro-3h-1,4-benzodiazepin-2(1h)-one

Country Status (7)

Country Link
US (1) US3335181A (de)
BR (1) BR6568465D0 (de)
CH (1) CH457457A (de)
DE (1) DE1545941C3 (de)
DK (1) DK120346B (de)
GB (1) GB1097951A (de)
IL (1) IL23206A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5706829A (en) * 1996-06-06 1998-01-13 Creighton University Method for treating neurocardiogenic syncope

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE75915C (de) * Dr. A. voswinkel, Apothekenbesitzer, in Berlin W., Kurfürsten-trafse 154 Verfahren zur Darstellung von Glycocollderivaten der Amidoacetophenone
BE513053A (de) * 1951-07-26
US3136815A (en) * 1959-12-10 1964-06-09 Hoffmann La Roche Amino substituted benzophenone oximes and derivatives thereof

Also Published As

Publication number Publication date
DK120346B (da) 1971-05-17
GB1097951A (en) 1968-01-03
DE1545941B2 (de) 1975-04-03
US3335181A (en) 1967-08-08
DE1545941C3 (de) 1975-11-20
BR6568465D0 (pt) 1973-08-28
DE1545941A1 (de) 1969-12-18
CH457457A (de) 1968-06-15

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