DK120346B - Fremgangsmåde til fremstilling af 5-aryl-7-nitro-3H-1, 4-benzodiazepin-2(1H)-oner. - Google Patents

Fremgangsmåde til fremstilling af 5-aryl-7-nitro-3H-1, 4-benzodiazepin-2(1H)-oner.

Info

Publication number
DK120346B
DK120346B DK198765AA DK198765A DK120346B DK 120346 B DK120346 B DK 120346B DK 198765A A DK198765A A DK 198765AA DK 198765 A DK198765 A DK 198765A DK 120346 B DK120346 B DK 120346B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
nitro
aryl
ones
preparation
Prior art date
Application number
DK198765AA
Other languages
Danish (da)
English (en)
Inventor
A Focella
A Rachlin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK120346B publication Critical patent/DK120346B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198765AA 1964-04-17 1965-04-20 Fremgangsmåde til fremstilling af 5-aryl-7-nitro-3H-1, 4-benzodiazepin-2(1H)-oner. DK120346B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US360755A US3335181A (en) 1964-04-17 1964-04-17 Ammonolysis of 2-halo-2'-benzoyl-4'-nitroacetanilides

Publications (1)

Publication Number Publication Date
DK120346B true DK120346B (da) 1971-05-17

Family

ID=23419290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198765AA DK120346B (da) 1964-04-17 1965-04-20 Fremgangsmåde til fremstilling af 5-aryl-7-nitro-3H-1, 4-benzodiazepin-2(1H)-oner.

Country Status (7)

Country Link
US (1) US3335181A (de)
BR (1) BR6568465D0 (de)
CH (1) CH457457A (de)
DE (1) DE1545941C3 (de)
DK (1) DK120346B (de)
GB (1) GB1097951A (de)
IL (1) IL23206A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5706829A (en) * 1996-06-06 1998-01-13 Creighton University Method for treating neurocardiogenic syncope

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE75915C (de) * Dr. A. voswinkel, Apothekenbesitzer, in Berlin W., Kurfürsten-trafse 154 Verfahren zur Darstellung von Glycocollderivaten der Amidoacetophenone
NL82429C (de) * 1951-07-26
US3136815A (en) * 1959-12-10 1964-06-09 Hoffmann La Roche Amino substituted benzophenone oximes and derivatives thereof

Also Published As

Publication number Publication date
GB1097951A (en) 1968-01-03
DE1545941B2 (de) 1975-04-03
DE1545941A1 (de) 1969-12-18
CH457457A (de) 1968-06-15
BR6568465D0 (pt) 1973-08-28
DE1545941C3 (de) 1975-11-20
IL23206A (en) 1968-07-25
US3335181A (en) 1967-08-08

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