IL228218A - Formulation comprising a phenylaminopyrimidine derivative as active agent - Google Patents
Formulation comprising a phenylaminopyrimidine derivative as active agentInfo
- Publication number
- IL228218A IL228218A IL228218A IL22821813A IL228218A IL 228218 A IL228218 A IL 228218A IL 228218 A IL228218 A IL 228218A IL 22821813 A IL22821813 A IL 22821813A IL 228218 A IL228218 A IL 228218A
- Authority
- IL
- Israel
- Prior art keywords
- weight
- nrc
- surfactant
- present
- acid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 140
- 238000009472 formulation Methods 0.000 title abstract description 49
- XGXNTJHZPBRBHJ-UHFFFAOYSA-N n-phenylpyrimidin-2-amine Chemical compound N=1C=CC=NC=1NC1=CC=CC=C1 XGXNTJHZPBRBHJ-UHFFFAOYSA-N 0.000 title abstract description 11
- 230000009919 sequestration Effects 0.000 title 1
- LCPGCGAJBOWMIP-UHFFFAOYSA-N n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-3,5-bis(trifluoromethyl)benzamide Chemical compound C1=C(NC=2N=C(C=CN=2)C=2C=NC=CC=2)C(C)=CC=C1NC(=O)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1 LCPGCGAJBOWMIP-UHFFFAOYSA-N 0.000 claims abstract description 86
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- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 24
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- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1103860.1A GB2488788B (en) | 2011-03-07 | 2011-03-07 | Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response |
| PCT/IB2011/001842 WO2012120328A1 (en) | 2011-03-07 | 2011-08-10 | Formulation comprising phenylaminopyrimidine derivative as active agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL228218A true IL228218A (en) | 2016-06-30 |
Family
ID=43923331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL228218A IL228218A (en) | 2011-03-07 | 2013-09-01 | Formulation comprising a phenylaminopyrimidine derivative as active agent |
Country Status (33)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3389633T (pt) * | 2015-12-18 | 2021-08-05 | Natco Pharma Ltd | Composições farmacêuticas compreendendo derivados de fenilaminopirimidina |
| EP3397242B1 (en) * | 2015-12-29 | 2021-02-03 | Noivita S.R.L.S. | Lipophilic formulations |
| CN107184549B (zh) * | 2017-04-11 | 2020-11-20 | 江苏大学 | 一种尼达尼布自微乳制剂和其制成的软胶囊及制备方法 |
| CN107564610A (zh) * | 2017-10-20 | 2018-01-09 | 浙江中大元通特种电缆有限公司 | 一种陶瓷化硅橡胶绝缘护套不锈钢连锁铠装防火电缆 |
| PL3765024T3 (pl) | 2018-03-14 | 2024-08-05 | KaNDy Therapeutics Limited | <div>Nowa formulacja farmaceutyczna zawierająca podwójnych antagonistów receptora nk-1/nk-3</div> |
| EP3914234A4 (en) * | 2019-01-25 | 2022-09-14 | Shenzhen Pharmacin Co., Ltd. | PHARMACEUTICAL COMPOSITIONS |
| US12533358B1 (en) | 2025-05-14 | 2026-01-27 | Bayer Consumer Care Ag | Methods of treatment with elinzanetant |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| HU226114B1 (en) * | 1997-07-29 | 2008-04-28 | Upjohn Co | Self-emulsifying formulation for lipophilic compounds |
| US6248354B1 (en) * | 1999-03-04 | 2001-06-19 | Allergan Sales, Inc. | Capsule system |
| US7232825B2 (en) * | 2003-05-02 | 2007-06-19 | Guoqing P Chen | Phenylaminopyrimidine derivatives and methods of use |
| EP1498143A1 (en) | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids |
| JP5184887B2 (ja) * | 2004-09-09 | 2013-04-17 | ナトコ ファーマ リミテッド | ｂｃｒ−ａｂｌキナーゼの阻害剤としての新規フェニルアミノピリミジン誘導体 |
| EP1966186A1 (en) * | 2006-10-26 | 2008-09-10 | Sicor Inc. | Process for the preparation of imatinib |
| EP1920767A1 (en) * | 2006-11-09 | 2008-05-14 | Abbott GmbH & Co. KG | Melt-processed imatinib dosage form |
| KR101697363B1 (ko) * | 2007-04-30 | 2017-01-17 | 인터자인 테크놀로지스, 인코포레이티드 | 소수성 제제를 캡슐화하기 위해 사용되는 혼합 입체화학을 가지는 혼성 블록 공중합체 미셀 |
| US8067422B2 (en) * | 2008-03-04 | 2011-11-29 | Natco Pharma Limited | Crystal form of phenylamino pyrimidine derivatives |
| KR20100126464A (ko) | 2008-03-04 | 2010-12-01 | 낫코 파마 리미티드 | 페닐아미노 피리미딘 유도체의 결정 형태 |
| EA019819B1 (ru) * | 2008-05-23 | 2014-06-30 | ПАНМИРА ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Кристаллическая полиморфная форма с ингибитора белка, активирующего 5-липоксигеназу, фармацевтическая композиция на ее основе и применение в лечении |
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2011
- 2011-03-07 GB GB1103860.1A patent/GB2488788B/en not_active Expired - Fee Related
- 2011-08-10 PT PT117648519T patent/PT2683381E/pt unknown
- 2011-08-10 JP JP2013557180A patent/JP5788534B2/ja not_active Expired - Fee Related
- 2011-08-10 KR KR1020137026440A patent/KR101767296B1/ko not_active Expired - Fee Related
- 2011-08-10 PH PH1/2013/501844A patent/PH12013501844A1/en unknown
- 2011-08-10 CN CN201180069095.7A patent/CN103561742B/zh not_active Expired - Fee Related
- 2011-08-10 BR BR112013022930A patent/BR112013022930A2/pt not_active IP Right Cessation
- 2011-08-10 HR HRP20151382TT patent/HRP20151382T1/hr unknown
- 2011-08-10 EP EP11764851.9A patent/EP2683381B1/en active Active
- 2011-08-10 HU HUE11764851A patent/HUE025562T2/en unknown
- 2011-08-10 RS RS20150787A patent/RS54420B1/sr unknown
- 2011-08-10 PL PL11764851T patent/PL2683381T3/pl unknown
- 2011-08-10 SI SI201130592T patent/SI2683381T1/sl unknown
- 2011-08-10 DK DK11764851.9T patent/DK2683381T3/en active
- 2011-08-10 WO PCT/IB2011/001842 patent/WO2012120328A1/en not_active Ceased
- 2011-08-10 SG SG2013067319A patent/SG193349A1/en unknown
- 2011-08-10 CA CA2829015A patent/CA2829015C/en not_active Expired - Fee Related
- 2011-08-10 EA EA201391280A patent/EA024610B1/ru not_active IP Right Cessation
- 2011-08-10 US US14/003,445 patent/US9895367B2/en not_active Expired - Fee Related
- 2011-08-10 MY MYPI2013003265A patent/MY158693A/en unknown
- 2011-08-10 AU AU2011361921A patent/AU2011361921B2/en not_active Ceased
- 2011-08-10 ES ES11764851.9T patent/ES2554927T3/es active Active
- 2011-08-10 MX MX2013010160A patent/MX339130B/es active IP Right Grant
- 2011-08-10 AP AP2013007128A patent/AP4076A/en active
- 2011-08-10 NZ NZ614903A patent/NZ614903A/en not_active IP Right Cessation
- 2011-08-10 GE GEAP201113254A patent/GEP20156410B/en unknown
- 2011-10-08 UA UAA201310715A patent/UA111074C2/uk unknown
-
2013
- 2013-09-01 IL IL228218A patent/IL228218A/en active IP Right Grant
- 2013-09-04 ZA ZA2013/06643A patent/ZA201306643B/en unknown
- 2013-09-09 MA MA36236A patent/MA35088B1/fr unknown
- 2013-10-04 CO CO13236457A patent/CO6811851A2/es unknown
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2015
- 2015-09-29 SM SM201500235T patent/SMT201500235B/xx unknown
- 2015-11-26 CY CY20151101069T patent/CY1116968T1/el unknown
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