SMT201500235B - Formulazione comprendente derivato di fenilamminopirimidina come agente attivo - Google Patents

Formulazione comprendente derivato di fenilamminopirimidina come agente attivo

Info

Publication number
SMT201500235B
SMT201500235B SM201500235T SM201500235T SMT201500235B SM T201500235 B SMT201500235 B SM T201500235B SM 201500235 T SM201500235 T SM 201500235T SM 201500235 T SM201500235 T SM 201500235T SM T201500235 B SMT201500235 B SM T201500235B
Authority
SM
San Marino
Prior art keywords
formulation
active agent
phenylaminopyrimidine derivative
phenylaminopyrimidine
derivative
Prior art date
Application number
SM201500235T
Other languages
English (en)
Inventor
Durga Maheswari Parvataneni
Siddhartha Yedluri
Venkata Satyanarayana Appadwedula
Kali Satya Bhujanga Rao Adibhatla
Venkaiah Chowdary Nannapaneni
Original Assignee
Natco Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43923331&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201500235(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Natco Pharma Ltd filed Critical Natco Pharma Ltd
Publication of SMT201500235B publication Critical patent/SMT201500235B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SM201500235T 2011-03-07 2015-09-29 Formulazione comprendente derivato di fenilamminopirimidina come agente attivo SMT201500235B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1103860.1A GB2488788B (en) 2011-03-07 2011-03-07 Oral formulation of phenylaminopyrymidine compound with enhanced bioavailability and pharmacological response
PCT/IB2011/001842 WO2012120328A1 (en) 2011-03-07 2011-08-10 Formulation comprising phenylaminopyrimidine derivative as active agent

Publications (1)

Publication Number Publication Date
SMT201500235B true SMT201500235B (it) 2015-10-30

Family

ID=43923331

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500235T SMT201500235B (it) 2011-03-07 2015-09-29 Formulazione comprendente derivato di fenilamminopirimidina come agente attivo

Country Status (32)

Country Link
US (1) US9895367B2 (it)
EP (1) EP2683381B1 (it)
JP (1) JP5788534B2 (it)
KR (1) KR101767296B1 (it)
CN (1) CN103561742B (it)
AP (1) AP4076A (it)
AU (1) AU2011361921B2 (it)
BR (1) BR112013022930A2 (it)
CA (1) CA2829015C (it)
CO (1) CO6811851A2 (it)
CY (1) CY1116968T1 (it)
DK (1) DK2683381T3 (it)
EA (1) EA024610B1 (it)
ES (1) ES2554927T3 (it)
GB (1) GB2488788B (it)
GE (1) GEP20156410B (it)
HR (1) HRP20151382T1 (it)
HU (1) HUE025562T2 (it)
IL (1) IL228218A (it)
MA (1) MA35088B1 (it)
MX (1) MX339130B (it)
MY (1) MY158693A (it)
NZ (1) NZ614903A (it)
PL (1) PL2683381T3 (it)
PT (1) PT2683381E (it)
RS (1) RS54420B1 (it)
SG (1) SG193349A1 (it)
SI (1) SI2683381T1 (it)
SM (1) SMT201500235B (it)
UA (1) UA111074C2 (it)
WO (1) WO2012120328A1 (it)
ZA (1) ZA201306643B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2881883T3 (es) * 2015-12-18 2021-11-30 Natco Pharma Ltd Composiciones farmacéuticas que comprenden derivado de fenilaminopirimidina
EP3397242B1 (en) * 2015-12-29 2021-02-03 Noivita S.R.L.S. Lipophilic formulations
CN107184549B (zh) * 2017-04-11 2020-11-20 江苏大学 一种尼达尼布自微乳制剂和其制成的软胶囊及制备方法
CN107564610A (zh) * 2017-10-20 2018-01-09 浙江中大元通特种电缆有限公司 一种陶瓷化硅橡胶绝缘护套不锈钢连锁铠装防火电缆
CR20200385A (es) 2018-03-14 2021-05-21 Kandy Therapeutics Ltd Formulación farmacéutica novedosa que comprende antagonistas del receptor dual nk-1/nk-3
CN113473974A (zh) * 2019-01-25 2021-10-01 深圳市药欣生物科技有限公司 药物组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
WO1999006024A1 (en) * 1997-07-29 1999-02-11 Pharmacia & Upjohn Company Self-emulsifying formulation for lipophilic compounds
US6248354B1 (en) * 1999-03-04 2001-06-19 Allergan Sales, Inc. Capsule system
US7232825B2 (en) * 2003-05-02 2007-06-19 Guoqing P Chen Phenylaminopyrimidine derivatives and methods of use
EP1498143A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Self-emulsifying and self-microemulsifying formulations for the oral administration of taxoids
EP1786799B1 (en) 2004-09-09 2012-07-04 Natco Pharma Limited Novel phenylaminopyrimidine derivatives as inhibitors of bcr-abl kinase
WO2008051597A1 (en) * 2006-10-26 2008-05-02 Sicor Inc. Process for the preparation of imatinib
EP1920767A1 (en) * 2006-11-09 2008-05-14 Abbott GmbH & Co. KG Melt-processed imatinib dosage form
EP2073850B1 (en) * 2007-04-30 2010-10-27 Intezyne Technologies Inc. Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
US8067422B2 (en) * 2008-03-04 2011-11-29 Natco Pharma Limited Crystal form of phenylamino pyrimidine derivatives
KR20100126464A (ko) * 2008-03-04 2010-12-01 낫코 파마 리미티드 페닐아미노 피리미딘 유도체의 결정 형태
EP2285803A4 (en) * 2008-05-23 2011-10-05 Amira Pharmaceuticals Inc Inhibitor of 5-Lipoxygenase Activating Protein

Also Published As

Publication number Publication date
CO6811851A2 (es) 2013-12-16
UA111074C2 (uk) 2016-03-25
SI2683381T1 (sl) 2016-01-29
AU2011361921A1 (en) 2013-09-26
US20130338180A1 (en) 2013-12-19
CY1116968T1 (el) 2017-04-05
BR112013022930A2 (pt) 2016-12-06
MX2013010160A (es) 2013-12-06
SG193349A1 (en) 2013-10-30
GB2488788A (en) 2012-09-12
KR101767296B1 (ko) 2017-08-10
EA201391280A1 (ru) 2014-02-28
CA2829015C (en) 2018-01-02
GB2488788B (en) 2013-07-10
CA2829015A1 (en) 2012-09-13
ZA201306643B (en) 2014-11-26
EA024610B1 (ru) 2016-10-31
CN103561742A (zh) 2014-02-05
KR20140016926A (ko) 2014-02-10
MA35088B1 (fr) 2014-05-02
NZ614903A (en) 2014-08-29
AU2011361921B2 (en) 2016-06-09
US9895367B2 (en) 2018-02-20
HRP20151382T1 (hr) 2016-02-12
ES2554927T3 (es) 2015-12-28
JP2014507463A (ja) 2014-03-27
DK2683381T3 (en) 2015-12-21
PL2683381T3 (pl) 2016-06-30
IL228218A (en) 2016-06-30
CN103561742B (zh) 2016-04-27
JP5788534B2 (ja) 2015-09-30
PT2683381E (pt) 2015-11-02
WO2012120328A1 (en) 2012-09-13
EP2683381B1 (en) 2015-09-16
AU2011361921A2 (en) 2014-10-30
EP2683381A1 (en) 2014-01-15
GB201103860D0 (en) 2011-04-20
MY158693A (en) 2016-11-15
HUE025562T2 (en) 2016-03-29
AP4076A (en) 2017-03-23
MX339130B (es) 2016-05-13
GEP20156410B (en) 2015-12-10
RS54420B1 (en) 2016-04-28
AP2013007128A0 (en) 2013-09-30

Similar Documents

Publication Publication Date Title
IL251647B (en) Oral veterinary preparations for the treatment of parasites containing active factors that act systemically
SMT201700043B (it) Formulazioni di bendamustina
BR112014009634A2 (pt) preparação e agente terapêutico
BR112013013311A2 (pt) agente terapêutico de indução de citotoxicidade
CO6811868A2 (es) Combinaciones de principios activos
CO6950492A2 (es) Composiciones plaguicidas estables
BR112014012005A2 (pt) composições, métodos, formulação farmacêutica e artigo
DK2900645T3 (da) Herbicidt aktive 3-phenylisoxazolinderivater
SMT201500235B (it) Formulazione comprendente derivato di fenilamminopirimidina come agente attivo
SMT201500320B (it) Liofilizzazione di agente tensioattivo polmonare liposomale sintetico
HK1192152A1 (zh) 新型抗紅班活性劑和含相同的組合物
CR20140068A (es) Una formulación herbicida mejorada
CO6852077A2 (es) Composiciónes que comprenden ditiínas sustituidas fungicidas y compuestos activos adicionales
BR112014000015A2 (pt) formulação
CO6940426A2 (es) Formulaciones farmacéuticas
BR112013022556A2 (pt) composição farmacêutica aquosa semissólida contendo tapentadol
DK2868318T4 (da) Injicerbar formulering
DK3178474T3 (da) Farmaceutisk formulering omfattende inositol
BR112013024082A2 (pt) composições de agente branqueador fluorescente
PL2836580T3 (pl) Mikrofibrylarna celuloza jako substancja czynna zdolna do odrywania brudu
ITTO20120461A1 (it) Agente per il controllo di ectoparassiti di animali.
BR112013031545A2 (pt) composições cosméticas
DE112013005825A5 (de) Reduktionsmittelzuführeinrichtung
DK3251507T3 (da) Forbedrede insekticidformuleringer
ITRE20110042A1 (it) Agente sanitario