IL225616A0 - Compounds that are similar to cyclosporine - Google Patents
Compounds that are similar to cyclosporineInfo
- Publication number
- IL225616A0 IL225616A0 IL225616A IL22561613A IL225616A0 IL 225616 A0 IL225616 A0 IL 225616A0 IL 225616 A IL225616 A IL 225616A IL 22561613 A IL22561613 A IL 22561613A IL 225616 A0 IL225616 A0 IL 225616A0
- Authority
- IL
- Israel
- Prior art keywords
- cyclosporin analogs
- cyclosporin
- analogs
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39245110P | 2010-10-12 | 2010-10-12 | |
| PCT/US2011/055788 WO2012051193A1 (en) | 2010-10-12 | 2011-10-11 | Cyclosporin analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL225616A0 true IL225616A0 (en) | 2013-06-27 |
Family
ID=44883796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL225616A IL225616A0 (en) | 2010-10-12 | 2013-04-07 | Compounds that are similar to cyclosporine |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9175042B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2627663B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5805773B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140026328A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103261212A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011316689B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013008749A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2814191A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL225616A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2013004062A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2013120927A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012051193A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100305047A1 (en) * | 2009-05-27 | 2010-12-02 | Allergan, Inc. | Cyclosporin derivatives for enhancing the growth of hair |
| AU2011342284C1 (en) * | 2010-12-15 | 2017-07-13 | Contravir Pharmaceuticals, Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
| CN104487449A (zh) * | 2012-06-01 | 2015-04-01 | 阿勒根公司 | 环孢菌素a类似物 |
| WO2014138437A1 (en) | 2013-03-08 | 2014-09-12 | Allergan, Inc. | Steroid conjugates |
| WO2016112321A1 (en) | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| US20180193003A1 (en) | 2016-12-07 | 2018-07-12 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US11523772B2 (en) | 2016-12-14 | 2022-12-13 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immunosuppressant |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| CN115028681B (zh) * | 2022-08-11 | 2022-11-15 | 中国科学院微生物研究所 | 一种降解亲环素a的嵌合体化合物及其制备方法与应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649047A (en) | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| FR2757522B1 (fr) * | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757521B1 (fr) * | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2762843B1 (fr) | 1997-04-30 | 1999-12-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2772768B1 (fr) * | 1997-12-19 | 2000-01-14 | Rhone Poulenc Rorer Sa | Nouveau procede de preparation de derives de cyclosporine |
| HUP0102833A3 (en) | 1998-06-12 | 2002-03-28 | Chem Ag C | Cyclosporins, process for preparation thereof and their use |
| US6254860B1 (en) * | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| CN100478025C (zh) * | 2005-03-25 | 2009-04-15 | 中国科学院上海药物研究所 | 一种环孢菌素a眼用微乳制剂及其制备方法 |
| DK2023918T3 (da) * | 2006-05-19 | 2011-04-26 | Scynexis Inc | Cyclosporiner til behandlingen og forebyggelse af okulære lidelser |
| CN101687013A (zh) * | 2007-05-04 | 2010-03-31 | 阿勒根公司 | 环孢菌素在治疗具有人工晶状体的患者中的用途 |
| BRPI0915552A2 (pt) | 2008-07-10 | 2017-06-20 | Allergan Inc | derivados de ciclosporina, seu uso e sua composição farmacêutica |
| CN107007815A (zh) | 2010-07-16 | 2017-08-04 | 美国科技环球有限公司 | 新颖的环孢霉素a衍生物在病毒感染的治疗和预防中的应用 |
| US9573978B2 (en) * | 2010-08-12 | 2017-02-21 | S&T Global, Inc. | Cyclosporin derivatives for the treatment and prevention of a viral infection |
| WO2012051194A1 (en) | 2010-10-12 | 2012-04-19 | Allergan, Inc. | Cyclosporin analogs |
| US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| ES2625502T3 (es) * | 2010-12-03 | 2017-07-19 | S&T Global Inc | Nuevos derivados de ciclosporina para el tratamiento y prevención de una infección vírica |
-
2011
- 2011-10-11 CN CN201180059696XA patent/CN103261212A/zh active Pending
- 2011-10-11 MX MX2013004062A patent/MX2013004062A/es unknown
- 2011-10-11 BR BR112013008749A patent/BR112013008749A2/pt not_active IP Right Cessation
- 2011-10-11 AU AU2011316689A patent/AU2011316689B2/en not_active Ceased
- 2011-10-11 US US13/270,929 patent/US9175042B2/en active Active
- 2011-10-11 CA CA2814191A patent/CA2814191A1/en not_active Abandoned
- 2011-10-11 EP EP11770984.0A patent/EP2627663B1/en not_active Not-in-force
- 2011-10-11 JP JP2013533941A patent/JP5805773B2/ja not_active Expired - Fee Related
- 2011-10-11 WO PCT/US2011/055788 patent/WO2012051193A1/en not_active Ceased
- 2011-10-11 RU RU2013120927/04A patent/RU2013120927A/ru not_active Application Discontinuation
- 2011-10-11 KR KR1020137012144A patent/KR20140026328A/ko not_active Withdrawn
-
2013
- 2013-04-07 IL IL225616A patent/IL225616A0/en unknown
-
2015
- 2015-10-02 US US14/873,908 patent/US9561259B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP5805773B2 (ja) | 2015-11-10 |
| AU2011316689B2 (en) | 2016-07-14 |
| RU2013120927A (ru) | 2014-11-20 |
| EP2627663B1 (en) | 2018-02-21 |
| US9175042B2 (en) | 2015-11-03 |
| BR112013008749A2 (pt) | 2019-09-24 |
| JP2013544786A (ja) | 2013-12-19 |
| MX2013004062A (es) | 2013-07-22 |
| US20160022765A1 (en) | 2016-01-28 |
| US20120135939A1 (en) | 2012-05-31 |
| EP2627663A1 (en) | 2013-08-21 |
| WO2012051193A1 (en) | 2012-04-19 |
| KR20140026328A (ko) | 2014-03-05 |
| CA2814191A1 (en) | 2012-04-19 |
| AU2011316689A1 (en) | 2013-05-02 |
| CN103261212A (zh) | 2013-08-21 |
| US9561259B2 (en) | 2017-02-07 |
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