IL225149B - Aqueous drug delivery system comprising off-flavor masking agent - Google Patents

Aqueous drug delivery system comprising off-flavor masking agent

Info

Publication number
IL225149B
IL225149B IL225149A IL22514913A IL225149B IL 225149 B IL225149 B IL 225149B IL 225149 A IL225149 A IL 225149A IL 22514913 A IL22514913 A IL 22514913A IL 225149 B IL225149 B IL 225149B
Authority
IL
Israel
Prior art keywords
unpalatable
delivery system
drug delivery
system containing
masking agent
Prior art date
Application number
IL225149A
Other languages
English (en)
Hebrew (he)
Original Assignee
Bev Rx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bev Rx Inc filed Critical Bev Rx Inc
Publication of IL225149B publication Critical patent/IL225149B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/84—Flavour masking or reducing agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL225149A 2010-09-13 2013-03-10 Aqueous drug delivery system comprising off-flavor masking agent IL225149B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38209810P 2010-09-13 2010-09-13
PCT/US2011/051386 WO2012037117A1 (en) 2010-09-13 2011-09-13 Aqueous drug delivery system comprising off - flavor masking agent
US13/231,150 US9018193B2 (en) 2010-09-13 2011-09-13 Aqueous drug delivery system

Publications (1)

Publication Number Publication Date
IL225149B true IL225149B (en) 2018-05-31

Family

ID=44674918

Family Applications (1)

Application Number Title Priority Date Filing Date
IL225149A IL225149B (en) 2010-09-13 2013-03-10 Aqueous drug delivery system comprising off-flavor masking agent

Country Status (15)

Country Link
US (4) US9018193B2 (OSRAM)
EP (2) EP3210597A1 (OSRAM)
JP (2) JP5890951B2 (OSRAM)
KR (1) KR20140007798A (OSRAM)
CN (1) CN103209684A (OSRAM)
AU (1) AU2011302293B2 (OSRAM)
BR (1) BR112013005987A2 (OSRAM)
CA (1) CA2811202A1 (OSRAM)
IL (1) IL225149B (OSRAM)
MY (1) MY162175A (OSRAM)
NZ (1) NZ608239A (OSRAM)
PH (1) PH12013500477A1 (OSRAM)
RU (1) RU2013116336A (OSRAM)
SG (2) SG10201507554RA (OSRAM)
WO (1) WO2012037117A1 (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015258900B2 (en) * 2014-05-16 2020-07-09 Vivus Llc Orally administrable formulations for the controlled release of a pharmacologically active agent
US11623008B2 (en) * 2014-08-20 2023-04-11 Professional Compounding Centers Of America Excipient compositions for mucoadhesive pharmaceutical compositions including a synergistic combination of amylopectin, pullulan, hyaluronic acid, and xyloglucan
US10137096B2 (en) 2014-12-09 2018-11-27 Ezekiel Golan Binge behavior regulators
CN114403335A (zh) * 2014-12-09 2022-04-29 以西结·戈兰 酒精饮料替代品
US11345762B2 (en) * 2015-04-07 2022-05-31 Nissan Chemical Industries, Ltd. Method for preparing liquid medium composition, and preparation device and kit therefor
US10493083B2 (en) 2015-10-30 2019-12-03 Cmp Development Llc Spironolactone aqueous compositions
WO2018048779A1 (en) * 2016-09-06 2018-03-15 Children's Medical Center Corporation Topical trpv1 antagonists and methods and compositions thereof
WO2018053358A1 (en) * 2016-09-16 2018-03-22 Cydex Pharmaceuticals, Inc. Formulations containing acetaminophen and sulfoalkyl ether cyclodextrin
WO2019140403A1 (en) * 2018-01-15 2019-07-18 Seattle Gummy Company Semi-solid anti-histamine compositions and methods of making and using thereof
US10828286B2 (en) * 2018-05-24 2020-11-10 Gm Pharmaceuticals, Inc. Niacin and berberine compositions and methods of use thereof
SG11202013126QA (en) * 2018-06-29 2021-02-25 Roquette Freres NOVEL HYDROXYPROPYL-ß-CYCLODEXTRIN AND PROCESS FOR THE PRODUCTION THEREOF
JP2020019731A (ja) * 2018-07-31 2020-02-06 日本食品化工株式会社 アムロジピンベシル酸塩の苦味抑制剤
JP6711875B2 (ja) * 2018-08-29 2020-06-17 日本食品化工株式会社 マクロライド化合物の苦味抑制剤
US20210401017A1 (en) * 2020-12-11 2021-12-30 Jiangnan University Preparation Method of Starch-based Double Emulsion Embedding Fat-soluble Functional Factors
US11452690B1 (en) * 2021-01-27 2022-09-27 ECI Pharmaceuticals, LLC Oral liquid compositions comprising amlodipine besylate and methods of using the same
GR1010732B (el) * 2023-06-02 2024-07-25 Ιουλια Κλεωνος Τσετη Φαρμακευτικη συνθεση ιβουπροφαινης και παρακεταμολης για απο του στοματος χορηγηση
CN119185191A (zh) * 2024-09-12 2024-12-27 广东心宝药业科技有限公司 一种口服液药物口感的控制方法及系统

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
FR2647343B1 (fr) * 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
GB9226391D0 (en) 1992-12-18 1993-02-10 Cpc International Inc Xanthan gelling agents
US5362860A (en) 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
FR2704146B1 (fr) 1993-04-19 1995-07-13 Cripdom Microcapsules d'acide acétylsalicylique à libération contrôlée.
US5651980A (en) 1994-04-15 1997-07-29 Biohybrid Technologies, Inc. Methods of use of uncoated gel particles
US6319535B1 (en) 1995-11-28 2001-11-20 Laurence J. Shaw Confections that “swim” in a carbonated beverage
PL332669A1 (en) 1996-10-09 1999-09-27 Givaudan Roure Int Method of obtaining minute beads constituting a food additive
AU5453198A (en) 1996-11-29 1998-06-22 Monsanto Company Lubricious self-standing (intact) gel for oral delivery of biologically-active ingredients
US5776431A (en) 1997-03-26 1998-07-07 Galat; Alexander Water-soluble aspirin composition
US7727552B1 (en) 1997-03-28 2010-06-01 Eisai R&D Management Co., Ltd. Oral pharmaceutical preparations decreased in bitterness by masking
BE1011251A3 (fr) 1997-07-03 1999-06-01 Ucb Sa Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
DE59807484D1 (de) 1997-07-15 2003-04-17 Burghart Kurt Verfahren zum herstellen von stabilen acetylsalicylsäure-lösungen
JP2004500305A (ja) 1997-10-31 2004-01-08 フアルマシア・コーポレーシヨン ゲランゴムゲルを含む徐放性組成物
US6572898B2 (en) 1999-05-21 2003-06-03 Pts Labs Llc Electrolyte gels for maintaining hydration and rehydration
SK282717B6 (sk) 2000-03-10 2002-11-06 �Stav Experiment�Lnej Farmakol�Gie Sav Spôsob prípravy ultravysokomolekulových hyalurónanov
ATE375095T1 (de) 2000-10-16 2007-10-15 Pepsico Inc Verfahren zur herstellung von mit kalzium angereicherten getränken
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
WO2003072141A1 (en) * 2002-02-22 2003-09-04 Pharmacia Corporation Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride
US20090215735A1 (en) * 2002-02-25 2009-08-27 Alcon, Inc. Topical solution formulations containing a corticosteroid and a cyclodextrin
KR20040089628A (ko) 2002-03-04 2004-10-21 가부시키가이샤 메드렉스 생체내에서 상전이하는 액상 매트릭스 및 액상 경구 제제
AU2003246489A1 (en) 2002-07-19 2004-02-09 Vitalstate Canada Ltd. Oral delivery system containing a gel matrix and liposomes
WO2005000265A2 (en) 2002-09-11 2005-01-06 Elan Pharma International Ltd. Gel-stabilized nanoparticulate active agent compositions
US20060018972A1 (en) 2002-11-26 2006-01-26 Upm Pharmaceuticals, Inc. Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs
US7160565B2 (en) 2003-03-31 2007-01-09 Breakthru Products, Llc Hydration beverage and method of delivering nutrients
US8287897B2 (en) 2003-09-12 2012-10-16 Ryukakusan Co., Ltd. Bitterness-masking particulate jelly beverage
CA2542755A1 (en) 2003-10-17 2005-04-28 Medrx Co., Ltd. Biguanide drug-containing jelly preparation
IL160095A0 (en) 2004-01-28 2004-06-20 Yissum Res Dev Co Formulations for poorly soluble drugs
CA2547934C (en) * 2004-02-19 2013-05-21 Abbott Laboratories Methods of using gamma cyclodextrin to control blood glucose and insulin secretion
DK2258349T3 (da) * 2004-05-11 2014-10-13 Egalet Ltd Kvældbar doseringsform omfattende gellangummi
WO2005115341A2 (en) 2004-05-27 2005-12-08 Advanced Bionutrition Corporation Microparticles for oral delivery
CA2574602A1 (en) 2004-07-22 2006-02-02 Pfizer Products Inc. Taste masking formulation comprising the drug in a dissolution-retarded form and/or cyclodextrin in a dissolution-enhanced form
US20070092561A1 (en) 2005-06-24 2007-04-26 Don Milne Water-Soluble Aspirin Composition
US8715731B2 (en) 2006-03-22 2014-05-06 Isp Investments Inc. Process of reducing the bitter taste of water soluble actives by co-grinding the active with β cyclodextrin
PT103476B (pt) 2006-05-10 2008-09-19 Univ De Coimbra Processo de produção e isolamento de micro- e nanopartículas poliméricas contendo macromoléculas de natureza hidrofílica e termolábil
US7988992B2 (en) 2006-07-06 2011-08-02 KOS Life Sciences Abbott Laboratories Superporous hydrogels for heavy-duty applications
US20100015227A1 (en) 2006-07-14 2010-01-21 Amos Nussinovitch Dried electrified hydrocolloid gels having unique structure and porosity
US20090304784A1 (en) 2006-07-28 2009-12-10 V. Mane Fils Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component
GB0616794D0 (en) * 2006-08-24 2006-10-04 Arrow Int Ltd Solid dosage form
JP5205909B2 (ja) * 2006-10-18 2013-06-05 大正製薬株式会社 粘膜適用液剤
JP5048398B2 (ja) * 2007-06-13 2012-10-17 大蔵製薬株式会社 抗真菌剤の医薬組成物
US8974825B2 (en) 2007-07-06 2015-03-10 Lupin Limited Pharmaceutical compositions for gastrointestinal drug delivery
KR100937625B1 (ko) 2007-08-10 2010-01-20 주식회사 제닉 가용성 웹 공극필름 및 이의 제조방법
US9186640B2 (en) 2007-08-28 2015-11-17 Pepsico, Inc. Delivery and controlled release of encapsulated lipophilic nutrients
US20100215740A1 (en) * 2007-10-10 2010-08-26 Rubicon Research Private Limited Taste-masked orally disintegrating tablets of memantine hydrochloride
DK2201956T3 (da) 2007-10-12 2014-07-14 Ryukakusan Co Ltd Kornformet geleret drikkevare til medicinering og fremgangsmåde til fremstilling af samme
US20090104251A1 (en) 2007-10-22 2009-04-23 Sensient Flavors Inc. Heat stable microcapsules and methods for making and using the same
US8563066B2 (en) * 2007-12-17 2013-10-22 New World Pharmaceuticals, Llc Sustained release of nutrients in vivo
PL2222311T3 (pl) 2007-12-20 2013-08-30 Nutricia Nv Ciekły produkt zawierający nukleotydy/nukleozydy
JP5555184B2 (ja) 2008-02-06 2014-07-23 ユニバーシティ・オブ・イースト・アングリア 嚥下を支援するための組成物および方法
BRPI0910850B1 (pt) 2008-04-21 2022-06-14 Otonomy, Inc. Composição intratimpânica compreendendo fator neurotrófico de crescimento derivado do cérebro (bdnf) para o tratamento ou prevenção da perda auditiva
US8791064B2 (en) 2008-04-24 2014-07-29 Technion Research And Development Foundation Ltd. Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
GB0813929D0 (en) 2008-07-30 2008-09-03 Glaxo Group Ltd Novel method
US9414615B2 (en) * 2010-01-18 2016-08-16 PepciCo, Inc. Gel-based compositions and methods of making same

Also Published As

Publication number Publication date
AU2011302293A1 (en) 2013-04-04
KR20140007798A (ko) 2014-01-20
US20180256725A1 (en) 2018-09-13
CA2811202A1 (en) 2012-03-22
WO2012037117A1 (en) 2012-03-22
BR112013005987A2 (pt) 2019-09-24
US20120122823A1 (en) 2012-05-17
SG10201507554RA (en) 2015-10-29
EP2616046A1 (en) 2013-07-24
CN103209684A (zh) 2013-07-17
PH12013500477A1 (en) 2018-01-17
RU2013116336A (ru) 2014-10-20
JP5890951B2 (ja) 2016-03-22
US20200114011A1 (en) 2020-04-16
EP2616046B1 (en) 2016-08-31
JP2016153401A (ja) 2016-08-25
US9789191B2 (en) 2017-10-17
JP2013537891A (ja) 2013-10-07
EP3210597A1 (en) 2017-08-30
US9018193B2 (en) 2015-04-28
NZ608239A (en) 2015-05-29
JP6263699B2 (ja) 2018-01-24
SG188509A1 (en) 2013-04-30
MY162175A (en) 2017-05-31
AU2011302293B2 (en) 2015-11-26
US20150209435A1 (en) 2015-07-30

Similar Documents

Publication Publication Date Title
IL225149B (en) Aqueous drug delivery system comprising off-flavor masking agent
PL2654864T3 (pl) System dostarczania leku
BR112013018828A2 (pt) sistemas de distribuição de droga
SMT201500232B (it) Dispositivo per la somministrazione de farmaci
BR112013012818A2 (pt) módulo medicamentoso e sistema de administração de fármaco
BRPI0917030A2 (pt) sistema de liberação de fármaco contendo progestina
DK2398500T3 (da) Glutathion-baseret lægemiddelafgivelsessystem
IL245328A0 (en) Pharmaceutical composition
IL243264B (en) Stabilizing agent for pharmaceutical proteins
BR112014005094A2 (pt) sistema de acesso vascular com conector
DK3520841T3 (da) Lægemiddelafgivelsesindretning
PL2706982T3 (pl) Donosowe farmaceutyczne postacie dawkowane zawierające nalokson
BR112013008891A2 (pt) módulo de base, módulo de bomba de base e sistema de bomba
BRPI1010279A2 (pt) dispositivo de distribuição de fármaco
BR112014002554A2 (pt) sistema de dispensação
BR112013016159A2 (pt) dispositivo de administração de substâncias em pó
BRPI1012730A2 (pt) dispositivo de distribuição de fármaco
FR2948568B1 (fr) Formulation pharmaceutique
ZA201207900B (en) Fast dissolving drug delivery systems
BRPI1010237A2 (pt) dispositivo de distribuição de fármaco
BR112012026686A2 (pt) fórmulas melhoradas para dispositivos médicos revestidos com droga
DK2652652T3 (da) Medikmentadministration
IL234363B (en) Pharmaceutical preparation containing an antivirally active dihydroquinazoline derivative
BR112015003811A2 (pt) sistema dispensador de medicamento
BR112012000799A2 (pt) dispositivo de distribuição de fármaco

Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees