IL218548A - A pharmaceutical preparation containing recombinant hcg - Google Patents

A pharmaceutical preparation containing recombinant hcg

Info

Publication number
IL218548A
IL218548A IL218548A IL21854812A IL218548A IL 218548 A IL218548 A IL 218548A IL 218548 A IL218548 A IL 218548A IL 21854812 A IL21854812 A IL 21854812A IL 218548 A IL218548 A IL 218548A
Authority
IL
Israel
Prior art keywords
pharmaceutical preparation
recombinant hcg
hcg
recombinant
pharmaceutical
Prior art date
Application number
IL218548A
Other languages
English (en)
Hebrew (he)
Other versions
IL218548A0 (en
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of IL218548A0 publication Critical patent/IL218548A0/en
Publication of IL218548A publication Critical patent/IL218548A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL218548A 2009-10-05 2012-03-08 A pharmaceutical preparation containing recombinant hcg IL218548A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09252360 2009-10-05
PCT/GB2010/001854 WO2011042688A1 (en) 2009-10-05 2010-10-04 Pharmaceutical preparation comprising recombinant hcg

Publications (2)

Publication Number Publication Date
IL218548A0 IL218548A0 (en) 2012-05-31
IL218548A true IL218548A (en) 2017-03-30

Family

ID=41471027

Family Applications (3)

Application Number Title Priority Date Filing Date
IL218548A IL218548A (en) 2009-10-05 2012-03-08 A pharmaceutical preparation containing recombinant hcg
IL250733A IL250733B (en) 2009-10-05 2017-02-23 A pharmaceutical preparation containing recombinant hcg
IL267556A IL267556A (en) 2009-10-05 2019-06-20 A pharmaceutical preparation containing recombinant hcg

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL250733A IL250733B (en) 2009-10-05 2017-02-23 A pharmaceutical preparation containing recombinant hcg
IL267556A IL267556A (en) 2009-10-05 2019-06-20 A pharmaceutical preparation containing recombinant hcg

Country Status (25)

Country Link
US (5) US8975226B2 (index.php)
EP (2) EP2486051B1 (index.php)
JP (6) JP6176924B2 (index.php)
KR (7) KR20230012104A (index.php)
CN (1) CN107050434B (index.php)
AR (2) AR079876A1 (index.php)
AU (1) AU2010304922B2 (index.php)
BR (1) BR112012007990A2 (index.php)
CA (1) CA2776790A1 (index.php)
DK (1) DK2486051T3 (index.php)
ES (2) ES3036152T3 (index.php)
HR (1) HRP20200941T1 (index.php)
HU (1) HUE050793T2 (index.php)
IL (3) IL218548A (index.php)
IN (1) IN2012DN02073A (index.php)
JO (1) JOP20200039A1 (index.php)
LT (1) LT2486051T (index.php)
MX (1) MX2012003951A (index.php)
PL (1) PL2486051T3 (index.php)
PT (1) PT2486051T (index.php)
RS (1) RS60413B1 (index.php)
RU (2) RU2724528C2 (index.php)
SI (1) SI2486051T1 (index.php)
TW (2) TWI532495B (index.php)
WO (1) WO2011042688A1 (index.php)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI488640B (zh) 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 藥學製劑
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
CA3163525A1 (en) 2011-03-31 2012-10-04 Ferring Bv. Pharmaceutical preparation
AR090095A1 (es) * 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
ES2784510T3 (es) 2012-12-10 2020-09-28 Seikagaku Kogyo Co Ltd Método para producir un nuevo Factor C recombinante, método para mitigar la inhibición de la reacción en ensayos de endotoxina, y método para medir endotoxina
JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
MX389908B (es) * 2015-04-24 2025-03-20 Ferring Bv Metodo de produccion de gonadotrofina.
MY179524A (en) 2015-06-26 2020-11-10 Ferring Bv Methods of purification and/or viral inactivation
HUE071268T2 (hu) * 2018-04-30 2025-08-28 Ferring Bv Készítmény szabályozott petefészek-stimuláláshoz
IL295278A (en) * 2020-02-05 2022-10-01 Novartis Ag cho cell expressing heterodimers of il-15
CN116199742B (zh) * 2022-07-06 2025-01-24 华兰基因工程有限公司 一种重组人绒毛膜促性腺激素Fc融合蛋白制备方法

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IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
DE69524456T2 (de) * 1995-03-21 2002-08-01 Applied Research Systems Flüssige hcg-formulierungen
TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
ES2268781T3 (es) 1997-06-25 2007-03-16 Applied Research Systems Ars Holding N.V. Analogos de hormonas glicoproteinicas reticuladas con disulfuro, su preparacion y uso.
US6500627B1 (en) 1998-02-03 2002-12-31 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by HCG assay
WO2003050286A1 (en) * 2001-10-29 2003-06-19 Crucell Holland B.V. Methods and means for producing proteins with predetermined post-translational modifications
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HK1045261A1 (zh) 1999-05-07 2002-11-22 Laboratoires Serono S.A. 促性腺激素
ME00296B (me) 2000-02-22 2011-05-10 Applied Res Systems Ars Holding N V PROCES PREČIŠĆAVANJA hCG I REKOMBINANTNOG hCG PREČIŠĆENOG TOM METODOM
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PL369606A1 (en) * 2001-10-22 2005-05-02 Applied Research Systems Ars Holding N.V. Gonadotrophins for folliculogenesis
CN1374525A (zh) * 2001-12-31 2002-10-16 陕西超英生物医学研究开发有限公司 一种抗体芯片、其制备技术及其检测方法
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
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KR100809945B1 (ko) * 2006-02-01 2008-03-05 대한민국 인체장내정상세균총 특이반응 ｄｎａ칩 및 이를 이용한인체장내정상세균총의 변화에 의한 인체 위해성의 평가방법
WO2008011633A2 (en) * 2006-07-21 2008-01-24 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US20100075375A1 (en) * 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
TWI488640B (zh) * 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 藥學製劑
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
CA3163525A1 (en) * 2011-03-31 2012-10-04 Ferring Bv. Pharmaceutical preparation
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض

Also Published As

Publication number Publication date
CN102549011A (zh) 2012-07-04
ES3036152T3 (en) 2025-09-15
JP2021176867A (ja) 2021-11-11
US11292824B2 (en) 2022-04-05
IL250733A0 (en) 2017-04-30
US20130023476A1 (en) 2013-01-24
KR20210014767A (ko) 2021-02-09
RU2724528C2 (ru) 2020-06-23
RU2588650C2 (ru) 2016-07-10
KR101804479B1 (ko) 2017-12-05
US20180030107A1 (en) 2018-02-01
JP6580104B2 (ja) 2019-09-25
IL218548A0 (en) 2012-05-31
PL2486051T3 (pl) 2020-09-07
LT2486051T (lt) 2020-07-10
EP2486051B1 (en) 2020-03-25
US8975226B2 (en) 2015-03-10
BR112012007990A2 (pt) 2017-07-25
EP3611185B1 (en) 2025-04-30
EP2486051A1 (en) 2012-08-15
US10526390B2 (en) 2020-01-07
SI2486051T1 (sl) 2020-08-31
KR102489143B1 (ko) 2023-01-13
JP2023075144A (ja) 2023-05-30
TWI532495B (zh) 2016-05-11
TW201632198A (zh) 2016-09-16
JP7196244B2 (ja) 2022-12-26
RU2016118236A3 (index.php) 2019-09-18
AU2010304922B2 (en) 2014-11-06
AR079876A1 (es) 2012-02-29
RS60413B1 (sr) 2020-07-31
IN2012DN02073A (index.php) 2015-08-21
RU2012112907A (ru) 2013-11-10
JOP20200039A1 (ar) 2022-10-30
US20140249082A1 (en) 2014-09-04
HRP20200941T1 (hr) 2020-09-18
JP2016074680A (ja) 2016-05-12
MX2012003951A (es) 2012-05-29
CN107050434B (zh) 2021-07-27
WO2011042688A1 (en) 2011-04-14
KR20190028823A (ko) 2019-03-19
CN107050434A (zh) 2017-08-18
RU2016118236A (ru) 2018-10-29
ES2798258T3 (es) 2020-12-10
DK2486051T3 (da) 2020-06-22
JP6310440B2 (ja) 2018-04-11
PT2486051T (pt) 2020-06-17
AR125991A2 (es) 2023-08-30
US20200247863A1 (en) 2020-08-06
JP7292153B2 (ja) 2023-06-16
KR102213154B1 (ko) 2021-02-05
KR20120094909A (ko) 2012-08-27
TWI604850B (zh) 2017-11-11
EP3611185A1 (en) 2020-02-19
KR20210141771A (ko) 2021-11-23
TW201113030A (en) 2011-04-16
US20220340634A1 (en) 2022-10-27
KR101987982B1 (ko) 2019-06-11
JP2020000246A (ja) 2020-01-09
US12234272B2 (en) 2025-02-25
CA2776790A1 (en) 2011-04-14
HUE050793T2 (hu) 2021-01-28
JP2013506708A (ja) 2013-02-28
KR20230012104A (ko) 2023-01-25
KR20170133531A (ko) 2017-12-05
AU2010304922A1 (en) 2012-03-29
IL267556A (en) 2019-08-29
US9676835B2 (en) 2017-06-13
KR20190067256A (ko) 2019-06-14
JP2018076296A (ja) 2018-05-17
JP6176924B2 (ja) 2017-08-09
IL250733B (en) 2019-07-31

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