IL212955A0 - Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof - Google Patents

Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Info

Publication number
IL212955A0
IL212955A0 IL212955A IL21295511A IL212955A0 IL 212955 A0 IL212955 A0 IL 212955A0 IL 212955 A IL212955 A IL 212955A IL 21295511 A IL21295511 A IL 21295511A IL 212955 A0 IL212955 A0 IL 212955A0
Authority
IL
Israel
Prior art keywords
manufacturing process
microcrystalline cellulose
cellulose based
directly compressible
based excipient
Prior art date
Application number
IL212955A
Other languages
English (en)
Original Assignee
Avantor Performance Mat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantor Performance Mat Inc filed Critical Avantor Performance Mat Inc
Publication of IL212955A0 publication Critical patent/IL212955A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL212955A 2008-11-19 2011-05-17 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof IL212955A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11602508P 2008-11-19 2008-11-19
PCT/US2009/064498 WO2010059534A2 (en) 2008-11-19 2009-11-16 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Publications (1)

Publication Number Publication Date
IL212955A0 true IL212955A0 (en) 2011-07-31

Family

ID=42077071

Family Applications (1)

Application Number Title Priority Date Filing Date
IL212955A IL212955A0 (en) 2008-11-19 2011-05-17 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Country Status (13)

Country Link
US (1) US20110288146A1 (enExample)
EP (1) EP2376067A2 (enExample)
JP (1) JP2012509329A (enExample)
KR (1) KR20110089180A (enExample)
CN (1) CN102215825A (enExample)
AU (1) AU2009316812A1 (enExample)
BR (1) BRPI0921507A2 (enExample)
CA (1) CA2744142A1 (enExample)
IL (1) IL212955A0 (enExample)
MX (1) MX2011005168A (enExample)
SG (1) SG171752A1 (enExample)
TW (1) TW201023897A (enExample)
WO (1) WO2010059534A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101298788B1 (ko) * 2011-03-15 2013-08-22 보령제약 주식회사 안정성이 개선된 복합제제
US9642807B2 (en) * 2012-04-27 2017-05-09 Japan Corn Starch Co., Ltd Method for producing starch granules, and orally disinitegrating tablet
SI2968529T1 (sl) 2013-03-14 2021-03-31 Aimmune Therapeutics, Inc. Izdelava arašidovih formulacij arašida za ustno desenzibilizacijo
US9492535B2 (en) 2013-03-14 2016-11-15 Aimmune Therapeutics, Inc. Peanut formulations and uses thereof
WO2015187736A1 (en) * 2014-06-02 2015-12-10 Allergen Research Corporation Placebo formulations and uses thereof
CN104189915B (zh) * 2014-07-30 2016-08-10 上海新亚药业闵行有限公司 一种固体制剂预混剂及其制备方法
CN104258411A (zh) * 2014-09-19 2015-01-07 安徽山河药用辅料股份有限公司 一种硅化微晶纤维素复合辅料及其制备方法
CN106265077A (zh) * 2015-05-30 2017-01-04 天士力制药集团股份有限公司 一种中药浸膏雾化分散工艺及其制剂
JP6650750B2 (ja) * 2015-12-22 2020-02-19 アサヒグループ食品株式会社 錠剤の製造方法、錠剤原料用顆粒の製造方法、及び錠剤原料用顆粒
EP3836801A4 (en) 2018-08-16 2022-05-18 Société des Produits Nestlé S.A. Peanut oral immunotherapy with maintenance dose
CN113891722A (zh) 2018-12-20 2022-01-04 爱沐疗法公司 用于漏服剂量的花生口服免疫疗法给药计划表
EP3965815A4 (en) 2019-05-10 2023-05-31 Société des Produits Nestlé S.A. METHOD OF IMPROVING THE QUALITY OF LIFE IN A PEANUT ALLERGY PATIENT
EP3993646B1 (en) 2019-07-05 2023-08-16 Swedish Match North Europe AB An oral pouched nicotine product including a filling material comprising nicotine-containing particles
HUE066565T2 (hu) 2019-11-20 2024-08-28 Swedish Match North Europe Ab Orálisan alkalmazható tasakos nikotintermék, beleértve egy nikotinrészecskéket tartalmazó töltõanyagot
PL4018848T3 (pl) 2020-12-22 2024-11-25 Swedish Match North Europe Ab Wyrób w saszetkach do użytku doustnego zawierający materiał pokrywający przepuszczalny dla cieczy oraz materiał wypełniający
CN116036291B (zh) * 2022-08-31 2025-08-26 瑞普（天津）生物药业有限公司 一种具有增溶作用的组合物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
CA2126441C (en) * 1991-12-30 1999-12-21 David F. Erkoboni Microcrystalline cellulose spheronization composition
US5686107A (en) * 1995-01-30 1997-11-11 Fmc Corporation Chewable pharmaceutical tablets
DE19628617A1 (de) * 1996-07-16 1998-01-22 Basf Ag Direkttablettierhilfsmittel
ES2301223T3 (es) * 1999-07-19 2008-06-16 Fit Gmbh Producto polisacaridico coprocesado con carboximetilcelulosa insoluble.
AU2002211018B2 (en) * 2000-11-06 2004-08-05 Asahi Kasei Kabushiki Kaisha Cellulosic particle for pharmaceutical preparation
US20040213839A1 (en) * 2001-02-05 2004-10-28 Andrew Favara Methods and compositions for reducing the taste of pharmaceutically active agents
NZ556465A (en) * 2005-02-03 2010-10-29 Nycomed Pharma As Fast wet-massing method for the preparation of calcium-containing compositions
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend
US8932629B2 (en) * 2006-10-27 2015-01-13 Fmc Corporation Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations
NZ584521A (en) * 2007-10-10 2011-03-31 Avantor Performance Mat Inc Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Also Published As

Publication number Publication date
MX2011005168A (es) 2011-05-30
US20110288146A1 (en) 2011-11-24
CA2744142A1 (en) 2010-05-27
KR20110089180A (ko) 2011-08-04
WO2010059534A3 (en) 2011-01-20
EP2376067A2 (en) 2011-10-19
WO2010059534A2 (en) 2010-05-27
TW201023897A (en) 2010-07-01
JP2012509329A (ja) 2012-04-19
AU2009316812A1 (en) 2011-07-07
CN102215825A (zh) 2011-10-12
SG171752A1 (en) 2011-07-28
BRPI0921507A2 (pt) 2016-01-19

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