IL212955A0 - Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof - Google Patents

Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Info

Publication number
IL212955A0
IL212955A0 IL212955A IL21295511A IL212955A0 IL 212955 A0 IL212955 A0 IL 212955A0 IL 212955 A IL212955 A IL 212955A IL 21295511 A IL21295511 A IL 21295511A IL 212955 A0 IL212955 A0 IL 212955A0
Authority
IL
Israel
Prior art keywords
manufacturing process
microcrystalline cellulose
cellulose based
directly compressible
based excipient
Prior art date
Application number
IL212955A
Other languages
English (en)
Original Assignee
Avantor Performance Mat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantor Performance Mat Inc filed Critical Avantor Performance Mat Inc
Publication of IL212955A0 publication Critical patent/IL212955A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IL212955A 2008-11-19 2011-05-17 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof IL212955A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11602508P 2008-11-19 2008-11-19
PCT/US2009/064498 WO2010059534A2 (en) 2008-11-19 2009-11-16 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Publications (1)

Publication Number Publication Date
IL212955A0 true IL212955A0 (en) 2011-07-31

Family

ID=42077071

Family Applications (1)

Application Number Title Priority Date Filing Date
IL212955A IL212955A0 (en) 2008-11-19 2011-05-17 Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Country Status (13)

Country Link
US (1) US20110288146A1 (enExample)
EP (1) EP2376067A2 (enExample)
JP (1) JP2012509329A (enExample)
KR (1) KR20110089180A (enExample)
CN (1) CN102215825A (enExample)
AU (1) AU2009316812A1 (enExample)
BR (1) BRPI0921507A2 (enExample)
CA (1) CA2744142A1 (enExample)
IL (1) IL212955A0 (enExample)
MX (1) MX2011005168A (enExample)
SG (1) SG171752A1 (enExample)
TW (1) TW201023897A (enExample)
WO (1) WO2010059534A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101298788B1 (ko) * 2011-03-15 2013-08-22 보령제약 주식회사 안정성이 개선된 복합제제
EP2842986B1 (en) * 2012-04-27 2018-12-26 Japan Corn Starch Co., Ltd. Method for producing starch granules, and orally disintegrating tablet
WO2014159609A1 (en) 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
MX2015010315A (es) 2013-03-14 2016-04-13 Aimmune Therapeutics Inc Fabricacion de formulaciones de mani para desensibilizacion oral.
US20150343075A1 (en) * 2014-06-02 2015-12-03 Aimmune Therapeutics Placebo formulations and uses thereof
CN104189915B (zh) * 2014-07-30 2016-08-10 上海新亚药业闵行有限公司 一种固体制剂预混剂及其制备方法
CN104258411A (zh) * 2014-09-19 2015-01-07 安徽山河药用辅料股份有限公司 一种硅化微晶纤维素复合辅料及其制备方法
CN106265077A (zh) * 2015-05-30 2017-01-04 天士力制药集团股份有限公司 一种中药浸膏雾化分散工艺及其制剂
JP6650750B2 (ja) * 2015-12-22 2020-02-19 アサヒグループ食品株式会社 錠剤の製造方法、錠剤原料用顆粒の製造方法、及び錠剤原料用顆粒
US12433945B2 (en) 2018-08-16 2025-10-07 Société des Produits Nestlé S.A. Peanut oral immunotherapy with maintenance dose
CA3123605A1 (en) 2018-12-20 2020-06-25 Aimmune Therapeutics, Inc. Peanut oral immunotherapy dosing schedule for missed doses
CA3137295A1 (en) 2019-05-10 2020-11-19 Aimmune Therapeutics, Inc. Methods for improving the quality of life of a patient with a peanut allergy
PH12021553026A1 (en) 2019-07-05 2023-08-23 Swedish Match North Europe Ab An oral pouched nicotine product including a filling material comprising nicotine-containing particles
HRP20231531T1 (hr) 2019-11-20 2024-03-01 Swedish Match North Europe Ab Nikotinski proizvod u vrećici za oralnu upotrebu koji uključuje materijal za punjenje koji sadržava čestice nikotina
EP4018848B1 (en) 2020-12-22 2024-09-18 Swedish Match North Europe AB A pouched product for oral use comprising a liquid permeable cover material and a filling material
CN116036291B (zh) * 2022-08-31 2025-08-26 瑞普（天津）生物药业有限公司 一种具有增溶作用的组合物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
CA2126441C (en) * 1991-12-30 1999-12-21 David F. Erkoboni Microcrystalline cellulose spheronization composition
US5686107A (en) * 1995-01-30 1997-11-11 Fmc Corporation Chewable pharmaceutical tablets
DE19628617A1 (de) * 1996-07-16 1998-01-22 Basf Ag Direkttablettierhilfsmittel
DE59914598D1 (de) * 1999-07-19 2008-02-14 Fit Gmbh Coprozessiertes Polysaccharidprodukt mit unlöslicher Carboxymethylcellulose
CN1222318C (zh) * 2000-11-06 2005-10-12 旭化成株式会社 制剂用纤维素粒子
CA2437375A1 (en) * 2001-02-05 2002-08-15 R.P. Scherer Technologies, Inc. Methods and compositions for reducing the taste of pharmaceutically active agents
CA2644400C (en) * 2005-02-03 2014-04-08 Nycomed Pharma As Fast wet-massing method for the preparation of calcium-containing compositions
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend
DE602007011792D1 (de) * 2006-10-27 2011-02-17 Fmc Corp Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen
WO2009048557A1 (en) * 2007-10-10 2009-04-16 Mallinckrodt Baker, Inc. Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof

Also Published As

Publication number Publication date
SG171752A1 (en) 2011-07-28
CA2744142A1 (en) 2010-05-27
MX2011005168A (es) 2011-05-30
TW201023897A (en) 2010-07-01
JP2012509329A (ja) 2012-04-19
CN102215825A (zh) 2011-10-12
KR20110089180A (ko) 2011-08-04
US20110288146A1 (en) 2011-11-24
WO2010059534A3 (en) 2011-01-20
BRPI0921507A2 (pt) 2016-01-19
AU2009316812A1 (en) 2011-07-07
EP2376067A2 (en) 2011-10-19
WO2010059534A2 (en) 2010-05-27

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