IL212275A0 - Synthetic mimetics of host defense and uses thereof - Google Patents
Synthetic mimetics of host defense and uses thereofInfo
- Publication number
- IL212275A0 IL212275A0 IL212275A IL21227511A IL212275A0 IL 212275 A0 IL212275 A0 IL 212275A0 IL 212275 A IL212275 A IL 212275A IL 21227511 A IL21227511 A IL 21227511A IL 212275 A0 IL212275 A0 IL 212275A0
- Authority
- IL
- Israel
- Prior art keywords
- host defense
- synthetic mimetics
- mimetics
- synthetic
- defense
- Prior art date
Links
- 230000007123 defense Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10859508P | 2008-10-27 | 2008-10-27 | |
| US12/605,584 US8278309B2 (en) | 2008-10-27 | 2009-10-26 | Synthetic mimetics of host defense and uses thereof |
| PCT/US2009/062147 WO2010062573A1 (en) | 2008-10-27 | 2009-10-27 | Synthetic mimetics of host defense and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL212275A0 true IL212275A0 (en) | 2011-06-30 |
Family
ID=42118100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL212275A IL212275A0 (en) | 2008-10-27 | 2011-04-12 | Synthetic mimetics of host defense and uses thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8278309B2 (enExample) |
| EP (1) | EP2358380A4 (enExample) |
| JP (1) | JP2012506908A (enExample) |
| KR (1) | KR20110074995A (enExample) |
| CN (1) | CN102256614B (enExample) |
| AU (1) | AU2009320139B2 (enExample) |
| BR (1) | BRPI0920251A2 (enExample) |
| CA (1) | CA2741764A1 (enExample) |
| IL (1) | IL212275A0 (enExample) |
| MX (1) | MX2011004360A (enExample) |
| RU (1) | RU2540077C2 (enExample) |
| TW (1) | TWI478915B (enExample) |
| UA (1) | UA104875C2 (enExample) |
| WO (1) | WO2010062573A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090092574A1 (en) * | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| TWI478915B (zh) * | 2008-10-27 | 2015-04-01 | Cellceutix Corp | 宿主防禦之合成模擬物及其用途 |
| DK2709619T3 (en) * | 2011-05-16 | 2018-01-15 | Cellceutix Corp | RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS |
| US9758607B2 (en) | 2013-10-10 | 2017-09-12 | Research Foundation Of The City University Of New York | Polymer with antibacterial activity |
| JP6047203B2 (ja) * | 2015-02-20 | 2016-12-21 | セルセウティックス コーポレイション | 消化管の炎症性疾患の予防および／または治療のための宿主防御タンパク質（ｈｄｐ）模倣薬 |
| CN107574581B (zh) * | 2017-08-03 | 2019-09-10 | 天津大学 | 一种抗菌性聚(ε-己内酯)/模拟抗菌肽电纺纤维膜及其制备方法 |
| WO2021209563A1 (en) | 2020-04-16 | 2021-10-21 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
| US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496179A (en) | 1967-10-11 | 1970-02-17 | Pfizer & Co C | 2-amino-3,4-dihydroquinazolines |
| AU665381B2 (en) | 1992-01-23 | 1996-01-04 | Morinaga Milk Industry Company Limited | Antibacterial agent and treatment of article therewith |
| ES2198139T3 (es) | 1998-08-20 | 2004-01-16 | The University Of North Carolina At Chapel Hill | Compuestos de dibenzotiofeno y procedimientos de uso de los mismos. |
| US6482799B1 (en) | 1999-05-25 | 2002-11-19 | The Regents Of The University Of California | Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial |
| JP2001261674A (ja) | 2000-03-22 | 2001-09-26 | Mitsui Chemicals Inc | ベンゾチオフェン誘導体およびそれを有効成分として含有する核内レセプター作動薬 |
| FR2813080B1 (fr) | 2000-08-17 | 2002-11-29 | Stago Diagnostica | Peptides anti-heparine |
| AU2002239545B2 (en) | 2000-11-08 | 2006-10-05 | Fxs Ventures, Llc | Improved ophthalmic and contact lens solutions with a peroxide source and a cationic polymeric preservative |
| AU2002326375B2 (en) | 2001-03-08 | 2006-12-21 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers as anti-infective agents |
| JP2005514368A (ja) * | 2001-11-21 | 2005-05-19 | スージェン・インコーポレーテッド | インドリノン誘導体を含む医薬製剤 |
| WO2003100701A1 (en) | 2002-05-28 | 2003-12-04 | The Trustees Of The University Of Pennsylvania | Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers |
| CA2489378A1 (en) | 2002-06-13 | 2003-12-24 | The Trustees Of The University Of Pennsylvania | Methods, systems, and computer program products for simulating biomembranes using coarse grain models |
| US9241917B2 (en) | 2003-03-17 | 2016-01-26 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers and oligomers and uses thereof |
| WO2004082643A2 (fr) | 2003-03-20 | 2004-09-30 | Shiseido International France | Composition cosmetique |
| US20050065091A1 (en) | 2003-09-18 | 2005-03-24 | Gholam Peyman | Stabilized ocular solutions |
| WO2005072246A2 (en) | 2004-01-23 | 2005-08-11 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof |
| BRPI0510119A (pt) * | 2004-04-23 | 2007-09-25 | Cydex Inc | formulação para dpi contendo sulfoaquil éter de ciclodextrina |
| CA2570248A1 (en) | 2004-06-15 | 2005-12-29 | Polymedix, Inc. | Polycationic compounds and uses thereof |
| EP2325218A1 (en) | 2004-07-23 | 2011-05-25 | The Trustees Of The University Of Pennsylvania | Antimicrobial copolymers and uses thereof |
| PL2486942T3 (pl) * | 2004-11-24 | 2019-05-31 | Meda Pharmaceuticals Inc | Kompozycje zawierające azelastynę oraz sposoby ich stosowania |
| CA2591744A1 (en) * | 2004-12-21 | 2006-06-29 | Pfizer Products Inc. | Stable non-dihydrate azithromycin oral suspensions |
| KR20080004475A (ko) | 2005-02-25 | 2008-01-09 | 유니버시티 오브 매사추세츠 | 표면적으로 양친매성인 중합체 및 올리고머, 그 조성물 및암치료방법으로서의 그 용도 |
| RU2325151C2 (ru) * | 2006-06-29 | 2008-05-27 | ООО "Научно-производственный центр "Амфион" | Способ получения системы доставки водонерастворимых и плохорастворимых биологически активных веществ и лекарственная форма на ее основе |
| JP2008137978A (ja) | 2006-12-05 | 2008-06-19 | Canon Inc | カルバゾール誘導体及びこれを用いた有機発光素子 |
| US20090092574A1 (en) * | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| WO2009061697A1 (en) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| AU2009276744A1 (en) | 2008-07-28 | 2010-02-04 | Polymedix, Inc. | Anti-malarial compounds |
| TWI478915B (zh) * | 2008-10-27 | 2015-04-01 | Cellceutix Corp | 宿主防禦之合成模擬物及其用途 |
-
2009
- 2009-10-26 TW TW098136112A patent/TWI478915B/zh active
- 2009-10-26 US US12/605,584 patent/US8278309B2/en not_active Expired - Fee Related
- 2009-10-27 RU RU2011121354/04A patent/RU2540077C2/ru not_active IP Right Cessation
- 2009-10-27 EP EP09829578A patent/EP2358380A4/en not_active Withdrawn
- 2009-10-27 CN CN200980151723.9A patent/CN102256614B/zh not_active Expired - Fee Related
- 2009-10-27 UA UAA201106679A patent/UA104875C2/uk unknown
- 2009-10-27 MX MX2011004360A patent/MX2011004360A/es active IP Right Grant
- 2009-10-27 KR KR1020117009356A patent/KR20110074995A/ko not_active Ceased
- 2009-10-27 BR BRPI0920251A patent/BRPI0920251A2/pt not_active IP Right Cessation
- 2009-10-27 CA CA2741764A patent/CA2741764A1/en not_active Abandoned
- 2009-10-27 JP JP2011534666A patent/JP2012506908A/ja active Pending
- 2009-10-27 AU AU2009320139A patent/AU2009320139B2/en not_active Ceased
- 2009-10-27 WO PCT/US2009/062147 patent/WO2010062573A1/en not_active Ceased
-
2011
- 2011-04-12 IL IL212275A patent/IL212275A0/en unknown
-
2012
- 2012-08-01 US US13/563,928 patent/US8975262B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20100105703A1 (en) | 2010-04-29 |
| UA104875C2 (uk) | 2014-03-25 |
| EP2358380A4 (en) | 2012-05-02 |
| US8278309B2 (en) | 2012-10-02 |
| TW201020249A (en) | 2010-06-01 |
| CN102256614B (zh) | 2014-01-08 |
| CA2741764A1 (en) | 2010-06-03 |
| RU2540077C2 (ru) | 2015-01-27 |
| US8975262B2 (en) | 2015-03-10 |
| US20130090345A1 (en) | 2013-04-11 |
| EP2358380A1 (en) | 2011-08-24 |
| WO2010062573A1 (en) | 2010-06-03 |
| AU2009320139B2 (en) | 2013-07-25 |
| BRPI0920251A2 (pt) | 2016-01-05 |
| MX2011004360A (es) | 2011-08-12 |
| RU2011121354A (ru) | 2012-12-10 |
| JP2012506908A (ja) | 2012-03-22 |
| AU2009320139A1 (en) | 2010-06-03 |
| TWI478915B (zh) | 2015-04-01 |
| CN102256614A (zh) | 2011-11-23 |
| KR20110074995A (ko) | 2011-07-05 |
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