IL208039A - Oxytocin analogs, their pharmaceutical compositions and their use in the preparation of a drug - Google Patents
Oxytocin analogs, their pharmaceutical compositions and their use in the preparation of a drugInfo
- Publication number
- IL208039A IL208039A IL208039A IL20803910A IL208039A IL 208039 A IL208039 A IL 208039A IL 208039 A IL208039 A IL 208039A IL 20803910 A IL20803910 A IL 20803910A IL 208039 A IL208039 A IL 208039A
- Authority
- IL
- Israel
- Prior art keywords
- medicament
- manufacture
- same
- pharmaceutical compositions
- oxytocin analogues
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Pregnancy & Childbirth (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4097308P | 2008-03-31 | 2008-03-31 | |
| EP08251739 | 2008-05-19 | ||
| PCT/IB2009/005351 WO2009122285A1 (en) | 2008-03-31 | 2009-03-30 | Oxitocin analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL208039A0 IL208039A0 (en) | 2010-12-30 |
| IL208039A true IL208039A (en) | 2016-03-31 |
Family
ID=39722695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL208039A IL208039A (en) | 2008-03-31 | 2010-09-07 | Oxytocin analogs, their pharmaceutical compositions and their use in the preparation of a drug |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8673841B2 (enExample) |
| EP (2) | EP2626364A1 (enExample) |
| JP (1) | JP5539310B2 (enExample) |
| KR (1) | KR101558404B1 (enExample) |
| CN (1) | CN101983205B (enExample) |
| AU (1) | AU2009233429B2 (enExample) |
| BR (1) | BRPI0910345B1 (enExample) |
| CA (1) | CA2718148C (enExample) |
| DK (1) | DK2260053T3 (enExample) |
| ES (1) | ES2488992T3 (enExample) |
| HR (1) | HRP20140716T1 (enExample) |
| IL (1) | IL208039A (enExample) |
| MX (1) | MX2010010743A (enExample) |
| NZ (1) | NZ587817A (enExample) |
| PL (1) | PL2260053T3 (enExample) |
| PT (1) | PT2260053E (enExample) |
| RU (1) | RU2496788C2 (enExample) |
| SI (1) | SI2260053T1 (enExample) |
| WO (1) | WO2009122285A1 (enExample) |
| ZA (1) | ZA201006733B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2575853B1 (en) | 2010-05-25 | 2016-08-24 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient |
| JO3400B1 (ar) * | 2010-09-30 | 2019-10-20 | Ferring Bv | مركب صيدلاني من كاربيتوسين |
| CA2895150C (en) | 2012-12-21 | 2019-11-26 | F. Hoffmann-La Roche Ag | Peptides as oxytocin agonists |
| PE20161559A1 (es) * | 2014-06-03 | 2017-01-12 | Hoffmann La Roche | Peptidos como agonistas de la oxitocina |
| CR20160562A (es) * | 2014-06-06 | 2017-01-06 | Hoffmann La Roche | Péptidos como agonistas de la oxitocina |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| EP3193907B1 (en) * | 2014-09-19 | 2020-01-01 | Ferring BV | Method of treating prader-willi syndrome |
| CN106084015B (zh) * | 2016-08-25 | 2020-01-31 | 成都圣诺生物制药有限公司 | 一种合成卡贝缩宫素的方法 |
| US20190135859A1 (en) | 2017-08-11 | 2019-05-09 | Ferring B.V. | Method of manufacturing a pharmaceutical composition |
| JP7789482B2 (ja) * | 2017-08-11 | 2025-12-22 | フェリング ベスローテン フェンノートシャップ | 医薬組成物を製造する方法 |
| CN107628975B (zh) * | 2017-09-17 | 2019-10-29 | 贵州医科大学 | 赖氨酸衍生物类组蛋白去乙酰化酶抑制剂及其合成和应用 |
| EP3852723B1 (en) | 2018-09-20 | 2025-11-05 | ACADIA Pharmaceuticals Inc. | Stable intranasal formulations of carbetocin |
| CA3112190A1 (en) | 2018-09-20 | 2020-03-26 | Levo Therapeutics, Inc. | Carbetocin drug product and process for preparing same |
| WO2020137880A1 (ja) * | 2018-12-27 | 2020-07-02 | 国立大学法人北海道大学 | オキシトシン誘導体及びその使用 |
| US20220313774A1 (en) * | 2019-11-04 | 2022-10-06 | Ferring B.V. | Intranasal administration of merotocin for improving lactation |
| US20230265124A1 (en) * | 2020-07-27 | 2023-08-24 | Az. Bd. of Reg. on Behalf of the Univ. of Arizona | Oxytocin analogues and methods for using the same |
| US20240197813A1 (en) * | 2021-03-26 | 2024-06-20 | Ot4B | Treatment of dysphagia |
| WO2024044633A2 (en) * | 2022-08-23 | 2024-02-29 | Seattle Children's Hospital (D/B/A Seattle Children's Research Institute) | Oxytocin derivatives and methods of use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9604341D0 (sv) * | 1996-11-26 | 1996-11-26 | Ferring Bv | Hepta-peptide oxytocin analogue |
| AU2003211011A1 (en) | 2002-02-27 | 2003-09-09 | Ferring Bv | Intermediates and methods for making heptapeptide oxytocin analogues |
-
2009
- 2009-03-30 NZ NZ587817A patent/NZ587817A/en unknown
- 2009-03-30 CN CN200980111919.5A patent/CN101983205B/zh active Active
- 2009-03-30 ES ES09727031.8T patent/ES2488992T3/es active Active
- 2009-03-30 US US12/933,858 patent/US8673841B2/en active Active
- 2009-03-30 EP EP13156710.9A patent/EP2626364A1/en not_active Withdrawn
- 2009-03-30 PL PL09727031T patent/PL2260053T3/pl unknown
- 2009-03-30 DK DK09727031.8T patent/DK2260053T3/da active
- 2009-03-30 PT PT97270318T patent/PT2260053E/pt unknown
- 2009-03-30 AU AU2009233429A patent/AU2009233429B2/en active Active
- 2009-03-30 BR BRPI0910345-7A patent/BRPI0910345B1/pt active IP Right Grant
- 2009-03-30 CA CA2718148A patent/CA2718148C/en active Active
- 2009-03-30 EP EP09727031.8A patent/EP2260053B1/en active Active
- 2009-03-30 HR HRP20140716AT patent/HRP20140716T1/hr unknown
- 2009-03-30 SI SI200930966T patent/SI2260053T1/sl unknown
- 2009-03-30 RU RU2010139634/04A patent/RU2496788C2/ru active
- 2009-03-30 KR KR1020107024207A patent/KR101558404B1/ko active Active
- 2009-03-30 JP JP2011502454A patent/JP5539310B2/ja active Active
- 2009-03-30 WO PCT/IB2009/005351 patent/WO2009122285A1/en not_active Ceased
- 2009-03-30 MX MX2010010743A patent/MX2010010743A/es active IP Right Grant
-
2010
- 2010-09-07 IL IL208039A patent/IL208039A/en active IP Right Grant
- 2010-09-20 ZA ZA2010/06733A patent/ZA201006733B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2718148C (en) | 2017-11-07 |
| SI2260053T1 (sl) | 2014-08-29 |
| RU2496788C2 (ru) | 2013-10-27 |
| KR101558404B1 (ko) | 2015-10-08 |
| BRPI0910345B1 (pt) | 2021-08-17 |
| CN101983205A (zh) | 2011-03-02 |
| US8673841B2 (en) | 2014-03-18 |
| CA2718148A1 (en) | 2009-10-08 |
| KR20110005705A (ko) | 2011-01-18 |
| ES2488992T3 (es) | 2014-09-01 |
| IL208039A0 (en) | 2010-12-30 |
| PL2260053T3 (pl) | 2014-11-28 |
| CN101983205B (zh) | 2015-08-19 |
| JP2011516460A (ja) | 2011-05-26 |
| MX2010010743A (es) | 2010-11-04 |
| WO2009122285A8 (en) | 2009-12-10 |
| RU2010139634A (ru) | 2012-05-10 |
| ZA201006733B (en) | 2011-06-29 |
| JP5539310B2 (ja) | 2014-07-02 |
| HK1146064A1 (en) | 2011-05-13 |
| DK2260053T3 (da) | 2014-06-23 |
| WO2009122285A1 (en) | 2009-10-08 |
| AU2009233429A1 (en) | 2009-10-08 |
| EP2626364A1 (en) | 2013-08-14 |
| HRP20140716T1 (hr) | 2014-08-29 |
| EP2260053B1 (en) | 2014-05-14 |
| US20110044905A1 (en) | 2011-02-24 |
| NZ587817A (en) | 2012-05-25 |
| BRPI0910345A2 (pt) | 2015-10-06 |
| AU2009233429B2 (en) | 2014-02-13 |
| EP2260053A1 (en) | 2010-12-15 |
| PT2260053E (pt) | 2014-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB20 | Patent renewed for 20 years |