IL201627A - Process for Preparation of 6 - {4 - [3 - ((r) -2 - Methyl-Pyrrolidine-1-Il) -Propoxy] -Phenyl} -2H-Pyridazine-3-On - Google Patents

Process for Preparation of 6 - {4 - [3 - ((r) -2 - Methyl-Pyrrolidine-1-Il) -Propoxy] -Phenyl} -2H-Pyridazine-3-On

Info

Publication number
IL201627A
IL201627A IL201627A IL20162709A IL201627A IL 201627 A IL201627 A IL 201627A IL 201627 A IL201627 A IL 201627A IL 20162709 A IL20162709 A IL 20162709A IL 201627 A IL201627 A IL 201627A
Authority
IL
Israel
Prior art keywords
methylpyrrolidine
tartrate
methyl
phenyl
propoxy
Prior art date
Application number
IL201627A
Other languages
English (en)
Hebrew (he)
Other versions
IL201627A0 (en
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of IL201627A0 publication Critical patent/IL201627A0/en
Publication of IL201627A publication Critical patent/IL201627A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
IL201627A 2007-05-03 2009-10-19 Process for Preparation of 6 - {4 - [3 - ((r) -2 - Methyl-Pyrrolidine-1-Il) -Propoxy] -Phenyl} -2H-Pyridazine-3-On IL201627A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03
PCT/US2008/005702 WO2008137087A1 (en) 2007-05-03 2008-05-02 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Publications (2)

Publication Number Publication Date
IL201627A0 IL201627A0 (en) 2010-05-31
IL201627A true IL201627A (en) 2014-06-30

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
IL201627A IL201627A (en) 2007-05-03 2009-10-19 Process for Preparation of 6 - {4 - [3 - ((r) -2 - Methyl-Pyrrolidine-1-Il) -Propoxy] -Phenyl} -2H-Pyridazine-3-On

Country Status (14)

Country Link
EP (1) EP2152669A1 (OSRAM)
JP (1) JP5698887B2 (OSRAM)
KR (1) KR20100017565A (OSRAM)
CN (1) CN101679237A (OSRAM)
AU (1) AU2008248168B2 (OSRAM)
BR (1) BRPI0810330A2 (OSRAM)
CA (1) CA2686033A1 (OSRAM)
EA (1) EA019031B1 (OSRAM)
IL (1) IL201627A (OSRAM)
MX (1) MX2009011787A (OSRAM)
NZ (1) NZ580948A (OSRAM)
UA (1) UA99913C2 (OSRAM)
WO (1) WO2008137087A1 (OSRAM)
ZA (1) ZA200907643B (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2658821C (en) 2006-07-25 2014-10-21 Cephalon, Inc. Pyridizinone derivatives and uses thereof to treat diseases, disorders and/or conditions that may be mediated or modulated by inhibition of h3 receptors
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
EP2752406A1 (en) * 2008-01-30 2014-07-09 Cephalon, Inc. Substituted pyridazine derivatives which have histamine H3 antagonist activity
HK1244789B (en) * 2014-12-23 2019-12-06 Cephalon, Inc. Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives
AR116299A1 (es) * 2018-09-07 2021-04-21 Sanofi Sa Sales de 6-(2,4-diclorofenil)-5-[4-[(3s)-1-(3-fluoropropil)pirrolidin-3-il]oxifenil]-8,9-dihidro-7h-benzo[7]anuleno-2-carboxilato de metilo y proceso de preparación de las mismas

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
CN100543050C (zh) 2004-03-08 2009-09-23 独立行政法人科学技术振兴机构 高分子担载金属簇组合物
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
PL1755593T3 (pl) 2004-06-02 2008-06-30 Hoffmann La Roche Pochodne naftalenu przydatne jako ligandy 3-receptora histaminowego
WO2006059778A1 (ja) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. 置換ピリドン誘導体
EP1831173B1 (en) 2004-12-17 2011-01-26 Janssen Pharmaceutica NV Tetrahydroisoquinoline compounds for treatment of cns disorders
CN101107231A (zh) 2005-01-21 2008-01-16 先灵公司 用作组胺h3拮抗剂的咪唑和苯并咪唑衍生物
EP1866293A1 (en) 2005-03-31 2007-12-19 UCB Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
US7943605B2 (en) 2005-10-27 2011-05-17 Ucb Pharma S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
ATE525072T1 (de) 2006-02-09 2011-10-15 Athersys Inc Pyrazole zur behandlung von adipositas und anderen zns-erkrankungen
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
WO2007105053A2 (en) 2006-03-13 2007-09-20 Pfizer Products Inc. Tetralines antagonists of the h-3 receptor
JP2009542673A (ja) 2006-06-29 2009-12-03 アリーナ ファーマシューティカルズ， インコーポレイテッド ヒスタミンｈ３−受容体関連障害の治療に有用なヒスタミンｈ３−受容体モジュレータ
CA2658821C (en) 2006-07-25 2014-10-21 Cephalon, Inc. Pyridizinone derivatives and uses thereof to treat diseases, disorders and/or conditions that may be mediated or modulated by inhibition of h3 receptors

Also Published As

Publication number Publication date
AU2008248168B2 (en) 2013-03-21
EA019031B1 (ru) 2013-12-30
KR20100017565A (ko) 2010-02-16
CA2686033A1 (en) 2008-11-13
MX2009011787A (es) 2009-11-13
JP2010526142A (ja) 2010-07-29
WO2008137087A1 (en) 2008-11-13
BRPI0810330A2 (pt) 2014-10-14
IL201627A0 (en) 2010-05-31
ZA200907643B (en) 2014-03-26
CN101679237A (zh) 2010-03-24
AU2008248168A1 (en) 2008-11-13
JP5698887B2 (ja) 2015-04-08
EA200971019A1 (ru) 2010-04-30
NZ580948A (en) 2011-04-29
EP2152669A1 (en) 2010-02-17
UA99913C2 (ru) 2012-10-25

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