IL198847A - Process for making 2-imino-thiazolidine-4-on and several such histories - Google Patents

Process for making 2-imino-thiazolidine-4-on and several such histories

Info

Publication number
IL198847A
IL198847A IL198847A IL19884709A IL198847A IL 198847 A IL198847 A IL 198847A IL 198847 A IL198847 A IL 198847A IL 19884709 A IL19884709 A IL 19884709A IL 198847 A IL198847 A IL 198847A
Authority
IL
Israel
Prior art keywords
derivatives
thiazolidin
imino
preparation
Prior art date
Application number
IL198847A
Other languages
English (en)
Hebrew (he)
Other versions
IL198847A0 (en
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of IL198847A0 publication Critical patent/IL198847A0/en
Publication of IL198847A publication Critical patent/IL198847A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL198847A 2006-11-23 2009-05-20 Process for making 2-imino-thiazolidine-4-on and several such histories IL198847A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (2)

Publication Number Publication Date
IL198847A0 IL198847A0 (en) 2010-02-17
IL198847A true IL198847A (en) 2015-07-30

Family

ID=39316391

Family Applications (1)

Application Number Title Priority Date Filing Date
IL198847A IL198847A (en) 2006-11-23 2009-05-20 Process for making 2-imino-thiazolidine-4-on and several such histories

Country Status (13)

Country Link
US (1) US8263780B2 (cg-RX-API-DMAC7.html)
EP (2) EP2489662B1 (cg-RX-API-DMAC7.html)
JP (1) JP4669564B2 (cg-RX-API-DMAC7.html)
KR (1) KR101255879B1 (cg-RX-API-DMAC7.html)
CN (2) CN101541772B (cg-RX-API-DMAC7.html)
AU (1) AU2007323042B2 (cg-RX-API-DMAC7.html)
CA (1) CA2669069C (cg-RX-API-DMAC7.html)
DK (2) DK2094676T3 (cg-RX-API-DMAC7.html)
ES (2) ES2410793T3 (cg-RX-API-DMAC7.html)
IL (1) IL198847A (cg-RX-API-DMAC7.html)
MX (1) MX2009005048A (cg-RX-API-DMAC7.html)
TW (1) TWI460166B (cg-RX-API-DMAC7.html)
WO (1) WO2008062376A2 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
AU2004295047B2 (en) 2003-11-21 2011-03-10 Laboratoires Juvise Pharmaceuticals 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
AU2009227629B2 (en) 2008-03-17 2014-09-04 Laboratoires Juvise Pharmaceuticals Dosing regimen for a selective S1P1 receptor agonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
SG11201704563RA (en) 2014-12-11 2017-07-28 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
EP3684358A4 (en) * 2017-09-19 2021-01-13 Teva Pharmaceuticals International GmbH NEW CRYSTALLINE POLYMORPHIC SHAPE OF PONESIMOD
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
TW202116742A (zh) * 2019-07-10 2021-05-01 德商拜耳廠股份有限公司 製備2-(苯基亞胺基)-1,3-四氫噻唑-4-酮之方法(二)
US20220315545A1 (en) * 2019-07-10 2022-10-06 Bayer Aktiengesellschaft Process of preparing 2-(phenylimino)-1,3-thiazolidin-4-ones
WO2021084068A1 (en) 2019-10-31 2021-05-06 Idorsia Pharmaceuticals Ltd Combination of a cxcr7 antagonist with an s1p1 receptor modulator
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
KR20220143032A (ko) * 2020-02-18 2022-10-24 바이엘 악티엔게젤샤프트 2-(페닐이미노)-3-알킬-1,3-티아졸리딘-4-온의 제조 방법
EP4387960A1 (en) 2021-08-17 2024-06-26 Teva Czech Industries s.r.o Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof
CN117924210A (zh) * 2024-01-22 2024-04-26 赣南师范大学 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
NL270002A (cg-RX-API-DMAC7.html) 1960-10-08
OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
CA2080917C (en) * 1990-04-27 2001-06-12 Reijo Baeckstroem New pharmacologically active catechol derivatives
TW221689B (cg-RX-API-DMAC7.html) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
CN1037842C (zh) * 1993-02-26 1998-03-25 大制药株式会社 取代的噻唑烷衍生物及其药物组合物和用途
KR960022486A (ko) 1994-12-29 1996-07-18 김준웅 신규 티아졸리딘-4-온 유도체
US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
CN1247553C (zh) 1999-09-14 2006-03-29 盐野义制药株式会社 2－亚氨基－1,3－噻嗪衍生物
PT1142885E (pt) * 1999-11-12 2007-02-28 Fujimoto Brothers Co Ltd Derivados de 2-(n-cianoimino)tiazolidin-4-ona
US20050019825A9 (en) * 2002-03-15 2005-01-27 Qing Dong Common ligand mimics: pseudothiohydantoins
EA011807B1 (ru) 2002-07-10 2009-06-30 Лаборатуар Сероно Са Азолидинонвинильные производные конденсированного бензола
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
UA80572C2 (en) * 2002-11-22 2007-10-10 Smithkline Beecham Corp THIAZOLIDINE DERIVATIVES AS hYAK3 INHIBITORS
US20040167192A1 (en) * 2003-01-16 2004-08-26 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
AU2004295047B2 (en) * 2003-11-21 2011-03-10 Laboratoires Juvise Pharmaceuticals 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
EP1718642A4 (en) * 2004-02-25 2010-11-24 Glaxosmithkline Llc NEW CHEMICAL COMPOUNDS
WO2006094233A1 (en) * 2005-03-03 2006-09-08 Sirtris Pharmaceuticals, Inc. N,n'-dicyclic isothiourea sirtuin modulators
AU2009227629B2 (en) * 2008-03-17 2014-09-04 Laboratoires Juvise Pharmaceuticals Dosing regimen for a selective S1P1 receptor agonist
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process

Also Published As

Publication number Publication date
TWI460166B (zh) 2014-11-11
BRPI0718986A2 (pt) 2014-02-11
DK2489662T3 (da) 2014-10-20
ES2523401T3 (es) 2014-11-25
EP2094676B1 (en) 2013-04-10
WO2008062376A2 (en) 2008-05-29
AU2007323042A1 (en) 2008-05-29
EP2094676A2 (en) 2009-09-02
CN103087004A (zh) 2013-05-08
CA2669069C (en) 2015-02-17
AU2007323042B2 (en) 2012-12-20
EP2489662A1 (en) 2012-08-22
CA2669069A1 (en) 2008-05-29
KR20090081009A (ko) 2009-07-27
US8263780B2 (en) 2012-09-11
WO2008062376A3 (en) 2008-07-10
US20100317867A1 (en) 2010-12-16
ES2410793T3 (es) 2013-07-03
IL198847A0 (en) 2010-02-17
JP2010510976A (ja) 2010-04-08
KR101255879B1 (ko) 2013-04-17
EP2489662B1 (en) 2014-08-06
CN101541772A (zh) 2009-09-23
DK2094676T3 (da) 2013-06-10
US20110201821A2 (en) 2011-08-18
CN101541772B (zh) 2013-04-17
JP4669564B2 (ja) 2011-04-13
MX2009005048A (es) 2009-05-25
TW200831474A (en) 2008-08-01

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