IL196405A0 - Processes for the synthesus of o-desmethylvenlafaxine - Google Patents

Processes for the synthesus of o-desmethylvenlafaxine

Info

Publication number
IL196405A0
IL196405A0 IL196405A IL19640509A IL196405A0 IL 196405 A0 IL196405 A0 IL 196405A0 IL 196405 A IL196405 A IL 196405A IL 19640509 A IL19640509 A IL 19640509A IL 196405 A0 IL196405 A0 IL 196405A0
Authority
IL
Israel
Prior art keywords
synthesus
desmethylvenlafaxine
processes
Prior art date
Application number
IL196405A
Other languages
English (en)
Original Assignee
Teva Pharma
Shenkar Natalia
Nidam Tamar
Niddam Hildesheim Valerie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Shenkar Natalia, Nidam Tamar, Niddam Hildesheim Valerie filed Critical Teva Pharma
Publication of IL196405A0 publication Critical patent/IL196405A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL196405A 2006-07-26 2009-01-08 Processes for the synthesus of o-desmethylvenlafaxine IL196405A0 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US83361606P 2006-07-26 2006-07-26
US83787906P 2006-08-14 2006-08-14
US84399806P 2006-09-11 2006-09-11
US84921606P 2006-10-03 2006-10-03
US84925506P 2006-10-03 2006-10-03
US90663907P 2007-03-12 2007-03-12
US90687907P 2007-03-13 2007-03-13
PCT/US2007/017009 WO2008013993A2 (en) 2006-07-26 2007-07-26 Processes for the synthesis of o-desmethylvenlafaxine

Publications (1)

Publication Number Publication Date
IL196405A0 true IL196405A0 (en) 2009-11-18

Family

ID=39750811

Family Applications (1)

Application Number Title Priority Date Filing Date
IL196405A IL196405A0 (en) 2006-07-26 2009-01-08 Processes for the synthesus of o-desmethylvenlafaxine

Country Status (4)

Country Link
JP (1) JP4763788B2 (ja)
CA (1) CA2656166A1 (ja)
IL (1) IL196405A0 (ja)
WO (1) WO2008013993A2 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109012737B (zh) * 2018-06-19 2021-09-17 陕西蒲城万德科技有限公司 一种抗抑郁药物中间体的催化合成方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3494954A (en) * 1967-06-19 1970-02-10 Cutter Lab 3,3-bis(phenyl)-2-(4-hydroxyphenyl)acrylonitriles
JPS57149257A (en) * 1981-03-13 1982-09-14 Nissan Chem Ind Ltd 4-benzyloxyphenylacetamide
ZA839073B (en) * 1982-12-13 1984-09-26 American Home Prod Phenethylamine derivatives and intermediates therefor
IE56324B1 (en) * 1982-12-13 1991-06-19 American Home Prod Phenethylamine derivatives and intermediates therefor
JPH10204057A (ja) * 1997-01-27 1998-08-04 Tosoh Corp ハロゲン化チオホルメート誘導体及びその製法
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
TWI228118B (en) * 2000-08-30 2005-02-21 Ciba Sc Holding Ag Process for the preparation of substituted phenylacetonitriles
CN1213994C (zh) * 2000-12-20 2005-08-10 西巴特殊化学品控股有限公司 制备苯乙胺衍生物的方法
DE10065442A1 (de) * 2000-12-27 2002-07-04 Bayer Ag Verbessertes Verfahren zur Herstellung von 2-(4-Trifluormethoxyphenyl)-ethylamin und von 4-Brommethyl- und 4-Chlormethyl-1-trifluormethoxy-benzol
US6673838B2 (en) * 2001-02-12 2004-01-06 Wyeth Succinate salt of O-desmethyl-venlafaxine
US6504044B2 (en) * 2001-02-28 2003-01-07 Council Of Scientific And Industrial Research Process for the preparation of 1-[cyano(aryl)methyl] cyclohexanol
KR20030000217A (ko) * 2001-06-22 2003-01-06 와이어쓰 시클로헥사놀 유도체의 제조방법
UA80543C2 (en) * 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
CN1232501C (zh) * 2002-11-29 2005-12-21 重庆凯林制药有限公司 用于制备万拉法新中间体的环己醇衍生物的制备工艺
CN101238094A (zh) * 2005-06-29 2008-08-06 Wyeth公司 制备1-[氰基(4-羟苯基)甲基]环己醇化合物的方法
EP1870395A1 (en) * 2006-06-19 2007-12-26 KRKA, D.D., Novo Mesto Process for preparation of o-desmethylvenlafaxine and its analogue

Also Published As

Publication number Publication date
WO2008013993A2 (en) 2008-01-31
WO2008013993A3 (en) 2008-04-10
JP4763788B2 (ja) 2011-08-31
JP2008545807A (ja) 2008-12-18
CA2656166A1 (en) 2008-01-31

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