IL193398A0 - Substantially pure o-desmethylvenlafaxine and processes for preparing it - Google Patents

Substantially pure o-desmethylvenlafaxine and processes for preparing it

Info

Publication number
IL193398A0
IL193398A0 IL193398A IL19339808A IL193398A0 IL 193398 A0 IL193398 A0 IL 193398A0 IL 193398 A IL193398 A IL 193398A IL 19339808 A IL19339808 A IL 19339808A IL 193398 A0 IL193398 A0 IL 193398A0
Authority
IL
Israel
Prior art keywords
desmethylvenlafaxine
preparing
processes
substantially pure
pure
Prior art date
Application number
IL193398A
Original Assignee
Teva Pharma
Niddam Hildesheim Valerie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Niddam Hildesheim Valerie filed Critical Teva Pharma
Publication of IL193398A0 publication Critical patent/IL193398A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL193398A 2006-04-17 2008-08-12 Substantially pure o-desmethylvenlafaxine and processes for preparing it IL193398A0 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US79280106P 2006-04-17 2006-04-17
US79673906P 2006-05-01 2006-05-01
US87295506P 2006-12-04 2006-12-04
US89916607P 2007-02-01 2007-02-01
US90241807P 2007-02-20 2007-02-20
US90398807P 2007-02-27 2007-02-27
PCT/US2007/009558 WO2007120923A1 (en) 2006-04-17 2007-04-17 Substantially pure o-desmethylvenlafaxine and processes for preparing it

Publications (1)

Publication Number Publication Date
IL193398A0 true IL193398A0 (en) 2009-05-04

Family

ID=39750904

Family Applications (1)

Application Number Title Priority Date Filing Date
IL193398A IL193398A0 (en) 2006-04-17 2008-08-12 Substantially pure o-desmethylvenlafaxine and processes for preparing it

Country Status (6)

Country Link
EP (1) EP2007708A1 (en)
JP (1) JP2008546718A (en)
CA (1) CA2646368A1 (en)
IL (1) IL193398A0 (en)
MX (1) MX2007016172A (en)
WO (1) WO2007120923A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007016179A (en) 2006-04-17 2008-03-11 Teva Pharma Polymorphic forms of tegaserod maleate.
WO2008035369A2 (en) * 2006-06-30 2008-03-27 Alembic Limited Novel form of o-desmethyl venlafaxine
US20090062572A1 (en) 2006-07-26 2009-03-05 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
WO2008013995A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Tridesmethylvenlafaxine and processes for the synthesis of o-desmethylvenlafaxine
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
US20100121108A1 (en) * 2006-08-04 2010-05-13 Medichem, S.A. Process for synthesizing desvenlafaxine free base and salts or solvates thereof
WO2008112313A2 (en) * 2007-03-14 2008-09-18 Teva Pharmaceutical Industries Ltd. Processes for preparing solid states of o-desmethylvenlafaxine succinate
US20110118357A1 (en) * 2007-10-26 2011-05-19 Generics Limited Process for preparing o-desmethylvenlafaxine
US8063250B2 (en) 2007-11-26 2011-11-22 Teva Pharmaceutical Industries, Ltd. Crystal forms of O-desmethylvenlafaxine fumarate
WO2009084038A2 (en) * 2007-12-28 2009-07-09 Ind-Swift Laboratories Limited Improved process for the preparation of 0-desmethyl-venlafaxine
WO2009151494A1 (en) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
CZ2008756A3 (en) 2008-11-27 2010-03-24 Zentiva, A. S. Process for preparing desvenlafaxine and salts thereof
ES2343050B1 (en) * 2008-12-16 2011-06-14 Chemo Iberica, S.A. PROCEDURE FOR THE PREPARATION OF DEVENLAFAXINE AND ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS.
CZ200969A3 (en) 2009-02-06 2010-06-30 Zentiva, K.S. Novel salts of desvenlafaxine and process of their preparation
CZ302145B6 (en) 2009-07-15 2010-11-10 Zentiva, K. S. Process for preparing desvenlafaxine and salts thereof
CA2795023A1 (en) 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
CZ303249B6 (en) 2010-04-06 2012-06-20 Zentiva, K.S. Process for preparing 4-(2-(substituted)-1-(1-hydroxycyclohexyl)ethyl)phenols by O-demethylation of their methyl ethers using odor free aromatic thiols
EP3580198B1 (en) 2017-02-09 2023-08-09 R L Finechem Private Limited A process for preparation of1-[2-(dimethylamino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
CZ20013607A3 (en) 1999-04-06 2002-06-12 Sepracor Inc. Pharmaceutical preparation
JP4220243B2 (en) 2001-02-12 2009-02-04 ワイス Novel succinate of O-desmethyl-venlafaxine
UA80543C2 (en) 2001-12-04 2007-10-10 Wyeth Corp Method for the preparation of o-desmethylvenlafaxine
WO2007071404A1 (en) * 2005-12-20 2007-06-28 Synthon B.V. Process for making desvenlafaxine

Also Published As

Publication number Publication date
JP2008546718A (en) 2008-12-25
MX2007016172A (en) 2008-03-10
WO2007120923A1 (en) 2007-10-25
CA2646368A1 (en) 2007-10-25
EP2007708A1 (en) 2008-12-31

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