IL194733A - Photo-disinfection devices and their use - Google Patents
Photo-disinfection devices and their useInfo
- Publication number
- IL194733A IL194733A IL194733A IL19473308A IL194733A IL 194733 A IL194733 A IL 194733A IL 194733 A IL194733 A IL 194733A IL 19473308 A IL19473308 A IL 19473308A IL 194733 A IL194733 A IL 194733A
- Authority
- IL
- Israel
- Prior art keywords
- light
- composition
- waveguide
- treatment
- microbes
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 35
- 238000011282 treatment Methods 0.000 claims description 101
- 239000000203 mixture Substances 0.000 claims description 93
- 239000003504 photosensitizing agent Substances 0.000 claims description 86
- 230000002165 photosensitisation Effects 0.000 claims description 64
- 206010033072 otitis externa Diseases 0.000 claims description 36
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical group C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims description 23
- 229960000907 methylthioninium chloride Drugs 0.000 claims description 23
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 10
- 229950000688 phenothiazine Drugs 0.000 claims description 10
- 229950003937 tolonium Drugs 0.000 claims description 7
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical group [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 claims description 7
- 239000004480 active ingredient Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 238000001126 phototherapy Methods 0.000 claims description 3
- 238000005286 illumination Methods 0.000 description 37
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- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 description 27
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
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- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 2
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- 150000002990 phenothiazines Chemical class 0.000 description 2
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- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
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- 210000001215 vagina Anatomy 0.000 description 2
- 241001263178 Auriparus Species 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
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- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 229930193140 Neomycin Natural products 0.000 description 1
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- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000035415 Reinfection Diseases 0.000 description 1
- 108010059993 Vancomycin Proteins 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 229960003022 amoxicillin Drugs 0.000 description 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
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- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
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- 238000000149 argon plasma sintering Methods 0.000 description 1
- 150000004036 bacteriochlorins Chemical class 0.000 description 1
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- 239000003085 diluting agent Substances 0.000 description 1
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- 229940047652 ear drops Drugs 0.000 description 1
- 210000000883 ear external Anatomy 0.000 description 1
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- 238000005457 optimization Methods 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 229960001019 oxacillin Drugs 0.000 description 1
- UWYHMGVUTGAWSP-JKIFEVAISA-N oxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=CC=CC=C1 UWYHMGVUTGAWSP-JKIFEVAISA-N 0.000 description 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 1
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- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2255—Optical elements at the distal end of probe tips
- A61B2018/2261—Optical elements at the distal end of probe tips with scattering, diffusion or dispersion of light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/0605—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/0607—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0644—Handheld applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
- Catching Or Destruction (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79634506P | 2006-04-28 | 2006-04-28 | |
| US86689706P | 2006-11-22 | 2006-11-22 | |
| PCT/US2007/067583 WO2007127894A2 (en) | 2006-04-28 | 2007-04-27 | Photodisinfection delivery devices & methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL194733A0 IL194733A0 (en) | 2009-08-03 |
| IL194733A true IL194733A (en) | 2014-05-28 |
Family
ID=38656401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL194733A IL194733A (en) | 2006-04-28 | 2008-10-22 | Photo-disinfection devices and their use |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7950396B2 (https=) |
| EP (3) | EP2012877B1 (https=) |
| JP (1) | JP5033178B2 (https=) |
| KR (1) | KR101373506B1 (https=) |
| CN (1) | CN101432044A (https=) |
| AU (1) | AU2007244735B2 (https=) |
| CA (1) | CA2650707A1 (https=) |
| IL (1) | IL194733A (https=) |
| WO (1) | WO2007127894A2 (https=) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040126272A1 (en) * | 2002-08-28 | 2004-07-01 | Eric Bornstein | Near infrared microbial elimination laser system |
| CA2642741A1 (en) * | 2006-01-24 | 2007-08-02 | Nomir Medical Technologies, Inc. | Optical method and device for modulation of biochemical processes in adipose tissue |
| US7950396B2 (en) * | 2006-04-28 | 2011-05-31 | Ondine International Holdings Ltd. | Treatment for otitis externa |
| FI121988B (fi) * | 2006-09-06 | 2011-07-15 | Valkee Oy | Kannettava elektroninen laite |
| WO2008067361A2 (en) * | 2006-11-28 | 2008-06-05 | Valam Corporation | Method and system for controlling the spread of microorganisms among subjects in a group |
| US8021405B2 (en) * | 2007-12-06 | 2011-09-20 | Susan Lemons White | Treatment of ear infection using blue/violet light |
| US20090149924A1 (en) * | 2007-12-06 | 2009-06-11 | Susan Lemons White | Treatment of ear infection using hands-free blue/violet light device |
| WO2009102756A1 (en) * | 2008-02-13 | 2009-08-20 | Andreas Rose | Light delivery device that provides a radial light output pattern |
| JP5457447B2 (ja) | 2008-07-10 | 2014-04-02 | スリーエム イノベイティブ プロパティズ カンパニー | 粘弾性導光材 |
| CN107037526A (zh) | 2008-08-08 | 2017-08-11 | 3M创新有限公司 | 具有粘弹性层的用于控制光的光导 |
| US20110251162A1 (en) * | 2008-09-25 | 2011-10-13 | Cedars-Sinai Medical Center | Methods of treatment for mrsa infections |
| US8977085B2 (en) | 2008-11-04 | 2015-03-10 | The University Of Queensland | Surface structure modification |
| GB0900461D0 (en) * | 2009-01-12 | 2009-02-11 | Photocure Asa | Photodynamic therapy device |
| WO2010142013A1 (en) * | 2009-06-08 | 2010-12-16 | Biolux Research Limited | Method and device for accelerating orthodontic tooth movement |
| BRPI1011746A2 (pt) | 2009-06-25 | 2018-02-06 | 3M Innovative Properties Co | artigos antimicrobianos ativados por luz e métodos de uso |
| US8721696B2 (en) | 2009-07-21 | 2014-05-13 | Valam Corporation | Selective treatments for chronic rhinosinusitis |
| WO2011027282A1 (en) * | 2009-09-04 | 2011-03-10 | Medlight S.A. | Fibre optic light delivery device with a glass fibre and a plastic fibre at its distal part |
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| EP2012877A2 (en) | 2009-01-14 |
| WO2007127894A2 (en) | 2007-11-08 |
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| CN101432044A (zh) | 2009-05-13 |
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| EP2368598A1 (en) | 2011-09-28 |
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| EP2012877B1 (en) | 2012-08-29 |
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| AU2007244735A1 (en) | 2007-11-08 |
| US20070255357A1 (en) | 2007-11-01 |
| KR101373506B1 (ko) | 2014-03-27 |
| US7950396B2 (en) | 2011-05-31 |
| US20080119914A1 (en) | 2008-05-22 |
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