IL194526A - Polypeptides with increased content of cialic acid, increased anti-inflammatory activity and reduced cell toxicity to cells, pharmaceutical formulations containing them and a method for their preparation - Google Patents
Polypeptides with increased content of cialic acid, increased anti-inflammatory activity and reduced cell toxicity to cells, pharmaceutical formulations containing them and a method for their preparationInfo
- Publication number
- IL194526A IL194526A IL194526A IL19452608A IL194526A IL 194526 A IL194526 A IL 194526A IL 194526 A IL194526 A IL 194526A IL 19452608 A IL19452608 A IL 19452608A IL 194526 A IL194526 A IL 194526A
- Authority
- IL
- Israel
- Prior art keywords
- sialic acid
- polypeptide
- region
- igg
- polypeptides containing
- Prior art date
Links
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- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
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2007
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2019
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