IL191674A - Compastatin Patent Analogs - Google Patents

Compastatin Patent Analogs

Info

Publication number
IL191674A
IL191674A IL191674A IL19167408A IL191674A IL 191674 A IL191674 A IL 191674A IL 191674 A IL191674 A IL 191674A IL 19167408 A IL19167408 A IL 19167408A IL 191674 A IL191674 A IL 191674A
Authority
IL
Israel
Prior art keywords
compstatin analogs
potent compstatin
potent
analogs
compstatin
Prior art date
Application number
IL191674A
Other languages
English (en)
Hebrew (he)
Other versions
IL191674A0 (en
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of IL191674A0 publication Critical patent/IL191674A0/en
Publication of IL191674A publication Critical patent/IL191674A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Analytical Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL191674A 2005-11-28 2008-05-22 Compastatin Patent Analogs IL191674A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74020505P 2005-11-28 2005-11-28
PCT/US2006/045539 WO2007062249A2 (en) 2005-11-28 2006-11-28 Potent compstatin analogs

Publications (2)

Publication Number Publication Date
IL191674A0 IL191674A0 (en) 2009-02-11
IL191674A true IL191674A (en) 2015-04-30

Family

ID=37964706

Family Applications (2)

Application Number Title Priority Date Filing Date
IL191674A IL191674A (en) 2005-11-28 2008-05-22 Compastatin Patent Analogs
IL237915A IL237915B (en) 2005-11-28 2015-03-24 A method for preparing potent analogues of compstatin and using them to prepare a medicine to inhibit the activation of the complement system

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL237915A IL237915B (en) 2005-11-28 2015-03-24 A method for preparing potent analogues of compstatin and using them to prepare a medicine to inhibit the activation of the complement system

Country Status (15)

Country Link
US (5) US7888323B2 (enExample)
EP (4) EP3363810A1 (enExample)
JP (2) JP5302004B2 (enExample)
CN (3) CN102977191B (enExample)
BR (1) BRPI0619023B1 (enExample)
CA (2) CA2971349C (enExample)
DK (1) DK1960422T3 (enExample)
ES (3) ES2677619T3 (enExample)
HR (1) HRP20120621T1 (enExample)
IL (2) IL191674A (enExample)
PL (1) PL1960422T3 (enExample)
PT (1) PT1960422E (enExample)
RS (1) RS52429B (enExample)
RU (2) RU2474586C2 (enExample)
WO (1) WO2007062249A2 (enExample)

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US8563259B2 (en) 2007-06-29 2013-10-22 The Trustees Of The University Of Pennsylvania Complement-mediated thrombophilic assay
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US20140219999A1 (en) 2011-04-01 2014-08-07 The Trustees Of The University Of Pennsylvania Treatment of colon cancer using complement inhibitors
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WO2015142701A1 (en) 2014-03-17 2015-09-24 The Trustees Of The University Of Pennsylvania Compstatin analogs with improved potency and pharmacokinetic properties
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Also Published As

Publication number Publication date
CN101400692B (zh) 2013-01-02
PT1960422E (pt) 2012-08-16
US20080227717A1 (en) 2008-09-18
WO2007062249A2 (en) 2007-05-31
DK1960422T3 (da) 2012-08-13
AU2006318333A1 (en) 2007-05-31
IL191674A0 (en) 2009-02-11
EP2377877B1 (en) 2018-03-28
JP2013177403A (ja) 2013-09-09
US20170305971A1 (en) 2017-10-26
BRPI0619023A2 (pt) 2011-09-20
CN101400692A (zh) 2009-04-01
US7888323B2 (en) 2011-02-15
EP1960422B1 (en) 2012-05-30
RU2474586C2 (ru) 2013-02-10
PL1960422T3 (pl) 2012-11-30
JP5927139B2 (ja) 2016-05-25
US20120004393A1 (en) 2012-01-05
HK1124621A1 (en) 2009-07-17
US20160096866A1 (en) 2016-04-07
CN106188239B (zh) 2020-01-07
IL237915B (en) 2018-11-29
CA2971349A1 (en) 2007-05-31
JP5302004B2 (ja) 2013-10-02
RU2656102C2 (ru) 2018-05-31
CN106188239A (zh) 2016-12-07
EP2377878B1 (en) 2018-03-28
CN102977191A (zh) 2013-03-20
HRP20120621T1 (hr) 2012-09-30
EP2377878A1 (en) 2011-10-19
BRPI0619023B1 (pt) 2022-09-27
ES2390828T3 (es) 2012-11-16
WO2007062249A3 (en) 2007-09-13
CN102977191B (zh) 2016-08-10
EP1960422A2 (en) 2008-08-27
ES2677619T3 (es) 2018-08-03
US20190016758A1 (en) 2019-01-17
CA2631443C (en) 2017-09-19
JP2009517476A (ja) 2009-04-30
US9169307B2 (en) 2015-10-27
CA2631443A1 (en) 2007-05-31
EP2377877A1 (en) 2011-10-19
CA2971349C (en) 2020-09-08
ES2677947T3 (es) 2018-08-07
RU2008126232A (ru) 2010-01-10
RU2012147267A (ru) 2014-05-20
RS52429B (sr) 2013-02-28
EP3363810A1 (en) 2018-08-22

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