IL188773A - תולדות אימידאזופירידין המותמרים בדיאוטריום ותכשירי רוקחות המכילים אותן - Google Patents
תולדות אימידאזופירידין המותמרים בדיאוטריום ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL188773A IL188773A IL188773A IL18877308A IL188773A IL 188773 A IL188773 A IL 188773A IL 188773 A IL188773 A IL 188773A IL 18877308 A IL18877308 A IL 18877308A IL 188773 A IL188773 A IL 188773A
- Authority
- IL
- Israel
- Prior art keywords
- deuterium
- pharmaceutical compositions
- compositions containing
- derivatives substituted
- imidazopyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05106868 | 2005-07-26 | ||
| PCT/EP2006/064666 WO2007012650A1 (en) | 2005-07-26 | 2006-07-26 | Isotopically substituted proton pump inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL188773A0 IL188773A0 (en) | 2008-08-07 |
| IL188773A true IL188773A (he) | 2014-02-27 |
Family
ID=35734406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL188773A IL188773A (he) | 2005-07-26 | 2008-01-15 | תולדות אימידאזופירידין המותמרים בדיאוטריום ותכשירי רוקחות המכילים אותן |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1910293A1 (he) |
| JP (1) | JP5448448B2 (he) |
| KR (1) | KR101358509B1 (he) |
| CN (2) | CN101268051B (he) |
| AR (1) | AR054584A1 (he) |
| AU (1) | AU2006274036B2 (he) |
| BR (1) | BRPI0614039A2 (he) |
| CA (1) | CA2615670C (he) |
| EA (1) | EA016814B1 (he) |
| IL (1) | IL188773A (he) |
| MX (1) | MX2008000901A (he) |
| NO (1) | NO20080839L (he) |
| NZ (1) | NZ565078A (he) |
| TW (1) | TWI394750B (he) |
| WO (1) | WO2007012650A1 (he) |
| ZA (1) | ZA200800303B (he) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI410409B (zh) * | 2005-07-26 | 2013-10-01 | Takeda Gmbh | 同位素取代之潘托拉唑（ｐａｎｔｏｐｒａｚｏｌｅ） |
| CA2624179A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties |
| WO2008127640A2 (en) * | 2007-04-11 | 2008-10-23 | Auspex Pharmaceuticals, Inc. | Substituted benzimidazoles |
| WO2008130863A2 (en) * | 2007-04-11 | 2008-10-30 | Auspex Pharmaceuticals, Inc. | Substituted benzimidazoles |
| ES2523921T3 (es) | 2010-02-12 | 2014-12-02 | Esteve Química, S.A. | Procedimiento de preparación de la sal sódica de esomeprazol |
| CN104530003A (zh) * | 2014-06-10 | 2015-04-22 | 广东东阳光药业有限公司 | 吡啶甲基亚磺酰基-1h-苯并咪唑类化合物的盐的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| JPH0643426B2 (ja) * | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | イミダゾ〔４，５−ｂ〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
| US6334997B1 (en) * | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| JP3696884B2 (ja) * | 1994-03-25 | 2005-09-21 | アイソテクニカ、インコーポレーテッド | ジュウテリウム化による薬物の効能の増強 |
| US6884429B2 (en) * | 1997-09-05 | 2005-04-26 | Isotechnika International Inc. | Medical devices incorporating deuterated rapamycin for controlled delivery thereof |
| NO309305B1 (no) * | 1999-02-19 | 2001-01-15 | Norsk Hydro As | Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater |
| DE10123129A1 (de) * | 2001-05-02 | 2002-11-14 | Berolina Drug Dev Ab Svedala | Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel |
| DE10162121A1 (de) * | 2001-12-12 | 2003-06-18 | Berolina Drug Dev Ab Svedala | Deuterierte substituierte Pyrazolyl-Benzolsulfonamide sowie diese Verbindungen enthaltende Arzneimittel |
| TWI410409B (zh) * | 2005-07-26 | 2013-10-01 | Takeda Gmbh | 同位素取代之潘托拉唑（ｐａｎｔｏｐｒａｚｏｌｅ） |
-
2006
- 2006-07-26 BR BRPI0614039-4A patent/BRPI0614039A2/pt not_active IP Right Cessation
- 2006-07-26 NZ NZ565078A patent/NZ565078A/en not_active IP Right Cessation
- 2006-07-26 CN CN2006800345034A patent/CN101268051B/zh not_active Expired - Fee Related
- 2006-07-26 CA CA2615670A patent/CA2615670C/en not_active Expired - Fee Related
- 2006-07-26 WO PCT/EP2006/064666 patent/WO2007012650A1/en not_active Ceased
- 2006-07-26 EA EA200800203A patent/EA016814B1/ru not_active IP Right Cessation
- 2006-07-26 AR ARP060103224A patent/AR054584A1/es unknown
- 2006-07-26 EP EP06764258A patent/EP1910293A1/en not_active Withdrawn
- 2006-07-26 MX MX2008000901A patent/MX2008000901A/es active IP Right Grant
- 2006-07-26 AU AU2006274036A patent/AU2006274036B2/en not_active Ceased
- 2006-07-26 CN CN2011100224850A patent/CN102134232B/zh not_active Expired - Fee Related
- 2006-07-26 KR KR1020087003989A patent/KR101358509B1/ko not_active Expired - Fee Related
- 2006-07-26 JP JP2008523354A patent/JP5448448B2/ja not_active Expired - Fee Related
- 2006-07-26 TW TW095127340A patent/TWI394750B/zh not_active IP Right Cessation
-
2008
- 2008-01-10 ZA ZA2008/00303A patent/ZA200800303B/en unknown
- 2008-01-15 IL IL188773A patent/IL188773A/he not_active IP Right Cessation
- 2008-02-18 NO NO20080839A patent/NO20080839L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ565078A (en) | 2010-03-26 |
| WO2007012650A1 (en) | 2007-02-01 |
| AR054584A1 (es) | 2007-06-27 |
| ZA200800303B (en) | 2009-01-28 |
| TW200714596A (en) | 2007-04-16 |
| JP2009502871A (ja) | 2009-01-29 |
| EA200800203A1 (ru) | 2008-08-29 |
| EA016814B1 (ru) | 2012-07-30 |
| AU2006274036A1 (en) | 2007-02-01 |
| KR101358509B1 (ko) | 2014-02-05 |
| IL188773A0 (en) | 2008-08-07 |
| NO20080839L (no) | 2008-02-18 |
| EP1910293A1 (en) | 2008-04-16 |
| CA2615670A1 (en) | 2007-02-01 |
| AU2006274036A2 (en) | 2008-03-20 |
| BRPI0614039A2 (pt) | 2011-03-09 |
| MX2008000901A (es) | 2008-03-26 |
| AU2006274036B2 (en) | 2012-05-24 |
| CN102134232B (zh) | 2012-11-21 |
| KR20080037676A (ko) | 2008-04-30 |
| HK1125098A1 (en) | 2009-07-31 |
| HK1160126A1 (en) | 2012-08-10 |
| CN101268051B (zh) | 2011-08-31 |
| JP5448448B2 (ja) | 2014-03-19 |
| CN102134232A (zh) | 2011-07-27 |
| TWI394750B (zh) | 2013-05-01 |
| CA2615670C (en) | 2015-01-20 |
| CN101268051A (zh) | 2008-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |