ZA200800303B - Isotopically substituted proton pump inhibitors - Google Patents
Isotopically substituted proton pump inhibitorsInfo
- Publication number
- ZA200800303B ZA200800303B ZA2008/00303A ZA200800303A ZA200800303B ZA 200800303 B ZA200800303 B ZA 200800303B ZA 2008/00303 A ZA2008/00303 A ZA 2008/00303A ZA 200800303 A ZA200800303 A ZA 200800303A ZA 200800303 B ZA200800303 B ZA 200800303B
- Authority
- ZA
- South Africa
- Prior art keywords
- proton pump
- pump inhibitors
- isotopically substituted
- substituted proton
- isotopically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05106868 | 2005-07-26 | ||
| PCT/EP2006/064666 WO2007012650A1 (en) | 2005-07-26 | 2006-07-26 | Isotopically substituted proton pump inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200800303B true ZA200800303B (en) | 2009-01-28 |
Family
ID=35734406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2008/00303A ZA200800303B (en) | 2005-07-26 | 2008-01-10 | Isotopically substituted proton pump inhibitors |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1910293A1 (en) |
| JP (1) | JP5448448B2 (en) |
| KR (1) | KR101358509B1 (en) |
| CN (2) | CN102134232B (en) |
| AR (1) | AR054584A1 (en) |
| AU (1) | AU2006274036B2 (en) |
| BR (1) | BRPI0614039A2 (en) |
| CA (1) | CA2615670C (en) |
| EA (1) | EA016814B1 (en) |
| HK (2) | HK1125098A1 (en) |
| IL (1) | IL188773A (en) |
| MX (1) | MX2008000901A (en) |
| NO (1) | NO20080839L (en) |
| NZ (1) | NZ565078A (en) |
| TW (1) | TWI394750B (en) |
| WO (1) | WO2007012650A1 (en) |
| ZA (1) | ZA200800303B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR054583A1 (en) * | 2005-07-26 | 2007-06-27 | Altana Pharma Ag | PANTOPRAZOL ISOTOPICALLY REPLACED |
| WO2007041630A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties |
| US20080255200A1 (en) * | 2007-04-11 | 2008-10-16 | Auspex Pharmaceuticals, Inc. | Substituted benzimidazoles |
| WO2008127640A2 (en) * | 2007-04-11 | 2008-10-23 | Auspex Pharmaceuticals, Inc. | Substituted benzimidazoles |
| ES2523921T3 (en) | 2010-02-12 | 2014-12-02 | Esteve Química, S.A. | Preparation procedure for esomeprazole sodium salt |
| CN104530003A (en) * | 2014-06-10 | 2015-04-22 | 广东东阳光药业有限公司 | Preparation method of salts of pyridylmethyl sulfinyl-1H-benzimidazole compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (en) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Gastric acid secretion |
| JPH0643426B2 (en) * | 1986-07-25 | 1994-06-08 | 東京田辺製薬株式会社 | Imidazo [4,5-b] pyridine derivative, method for producing the same, and antiulcer agent containing the same |
| US6334997B1 (en) * | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| WO1995026325A2 (en) * | 1994-03-25 | 1995-10-05 | Isotechnika Inc. | Enhancement of the efficacy of drugs by deuteration |
| US6884429B2 (en) * | 1997-09-05 | 2005-04-26 | Isotechnika International Inc. | Medical devices incorporating deuterated rapamycin for controlled delivery thereof |
| NO309305B1 (en) * | 1999-02-19 | 2001-01-15 | Norsk Hydro As | Use of benzaldehyde derivatives in the manufacture of pharmaceutical preparations for the prevention and / or treatment of cancer, as well as certain new benzaldehyde derivatives |
| DE10123129A1 (en) * | 2001-05-02 | 2002-11-14 | Berolina Drug Dev Ab Svedala | Deuterated 3-piperidinopropiophenones and medicinal products containing these compounds |
| DE10162121A1 (en) * | 2001-12-12 | 2003-06-18 | Berolina Drug Dev Ab Svedala | Deuterated substituted pyrazolyl-benzenesulfonamides and drugs containing these compounds |
| AR054583A1 (en) * | 2005-07-26 | 2007-06-27 | Altana Pharma Ag | PANTOPRAZOL ISOTOPICALLY REPLACED |
-
2006
- 2006-07-26 CN CN2011100224850A patent/CN102134232B/en not_active Expired - Fee Related
- 2006-07-26 KR KR1020087003989A patent/KR101358509B1/en not_active IP Right Cessation
- 2006-07-26 CN CN2006800345034A patent/CN101268051B/en not_active Expired - Fee Related
- 2006-07-26 AR ARP060103224A patent/AR054584A1/en unknown
- 2006-07-26 EP EP06764258A patent/EP1910293A1/en not_active Withdrawn
- 2006-07-26 WO PCT/EP2006/064666 patent/WO2007012650A1/en active Application Filing
- 2006-07-26 CA CA2615670A patent/CA2615670C/en not_active Expired - Fee Related
- 2006-07-26 TW TW095127340A patent/TWI394750B/en not_active IP Right Cessation
- 2006-07-26 BR BRPI0614039-4A patent/BRPI0614039A2/en not_active IP Right Cessation
- 2006-07-26 MX MX2008000901A patent/MX2008000901A/en active IP Right Grant
- 2006-07-26 AU AU2006274036A patent/AU2006274036B2/en not_active Ceased
- 2006-07-26 NZ NZ565078A patent/NZ565078A/en not_active IP Right Cessation
- 2006-07-26 JP JP2008523354A patent/JP5448448B2/en not_active Expired - Fee Related
- 2006-07-26 EA EA200800203A patent/EA016814B1/en not_active IP Right Cessation
-
2008
- 2008-01-10 ZA ZA2008/00303A patent/ZA200800303B/en unknown
- 2008-01-15 IL IL188773A patent/IL188773A/en not_active IP Right Cessation
- 2008-02-18 NO NO20080839A patent/NO20080839L/en not_active Application Discontinuation
-
2009
- 2009-03-12 HK HK09102398.5A patent/HK1125098A1/en not_active IP Right Cessation
-
2012
- 2012-01-18 HK HK12100603.5A patent/HK1160126A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2615670A1 (en) | 2007-02-01 |
| TW200714596A (en) | 2007-04-16 |
| EA016814B1 (en) | 2012-07-30 |
| AR054584A1 (en) | 2007-06-27 |
| EA200800203A1 (en) | 2008-08-29 |
| KR101358509B1 (en) | 2014-02-05 |
| NO20080839L (en) | 2008-02-18 |
| EP1910293A1 (en) | 2008-04-16 |
| CN101268051A (en) | 2008-09-17 |
| CN101268051B (en) | 2011-08-31 |
| CN102134232A (en) | 2011-07-27 |
| IL188773A (en) | 2014-02-27 |
| JP2009502871A (en) | 2009-01-29 |
| MX2008000901A (en) | 2008-03-26 |
| BRPI0614039A2 (en) | 2011-03-09 |
| NZ565078A (en) | 2010-03-26 |
| AU2006274036A2 (en) | 2008-03-20 |
| CN102134232B (en) | 2012-11-21 |
| JP5448448B2 (en) | 2014-03-19 |
| TWI394750B (en) | 2013-05-01 |
| AU2006274036B2 (en) | 2012-05-24 |
| CA2615670C (en) | 2015-01-20 |
| AU2006274036A1 (en) | 2007-02-01 |
| HK1125098A1 (en) | 2009-07-31 |
| WO2007012650A1 (en) | 2007-02-01 |
| HK1160126A1 (en) | 2012-08-10 |
| KR20080037676A (en) | 2008-04-30 |
| IL188773A0 (en) | 2008-08-07 |
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