IL188773A - History of Imidazopyridine Converted in the Deuterium and Pharmaceutical Preparations Containing Them - Google Patents

History of Imidazopyridine Converted in the Deuterium and Pharmaceutical Preparations Containing Them

Info

Publication number
IL188773A
IL188773A IL188773A IL18877308A IL188773A IL 188773 A IL188773 A IL 188773A IL 188773 A IL188773 A IL 188773A IL 18877308 A IL18877308 A IL 18877308A IL 188773 A IL188773 A IL 188773A
Authority
IL
Israel
Prior art keywords
deuterium
pharmaceutical compositions
compositions containing
derivatives substituted
imidazopyridine derivatives
Prior art date
Application number
IL188773A
Other languages
English (en)
Hebrew (he)
Other versions
IL188773A0 (en
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of IL188773A0 publication Critical patent/IL188773A0/en
Publication of IL188773A publication Critical patent/IL188773A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL188773A 2005-07-26 2008-01-15 History of Imidazopyridine Converted in the Deuterium and Pharmaceutical Preparations Containing Them IL188773A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05106868 2005-07-26
PCT/EP2006/064666 WO2007012650A1 (fr) 2005-07-26 2006-07-26 Inhibiteurs de pompe a protons isotopiquement substitues

Publications (2)

Publication Number Publication Date
IL188773A0 IL188773A0 (en) 2008-08-07
IL188773A true IL188773A (en) 2014-02-27

Family

ID=35734406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL188773A IL188773A (en) 2005-07-26 2008-01-15 History of Imidazopyridine Converted in the Deuterium and Pharmaceutical Preparations Containing Them

Country Status (17)

Country Link
EP (1) EP1910293A1 (fr)
JP (1) JP5448448B2 (fr)
KR (1) KR101358509B1 (fr)
CN (2) CN101268051B (fr)
AR (1) AR054584A1 (fr)
AU (1) AU2006274036B2 (fr)
BR (1) BRPI0614039A2 (fr)
CA (1) CA2615670C (fr)
EA (1) EA016814B1 (fr)
HK (2) HK1125098A1 (fr)
IL (1) IL188773A (fr)
MX (1) MX2008000901A (fr)
NO (1) NO20080839L (fr)
NZ (1) NZ565078A (fr)
TW (1) TWI394750B (fr)
WO (1) WO2007012650A1 (fr)
ZA (1) ZA200800303B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1912947A1 (fr) * 2005-07-26 2008-04-23 Nycomed GmbH Pantoprazole substitue d'un point de vue isotopique
CN101309917B (zh) * 2005-10-06 2013-09-11 奥斯拜客斯制药有限公司 具有增强治疗性质的胃h+,k+-atp酶氘代抑制剂
WO2008127640A2 (fr) * 2007-04-11 2008-10-23 Auspex Pharmaceuticals, Inc. Benzimidazoles substitués
WO2008130863A2 (fr) * 2007-04-11 2008-10-30 Auspex Pharmaceuticals, Inc. Benzimidazoles substitués
CN102770423B (zh) 2010-02-12 2014-10-15 埃斯特维化学股份有限公司 艾美拉唑的钠盐的制备方法
CN104530003A (zh) * 2014-06-10 2015-04-22 广东东阳光药业有限公司 吡啶甲基亚磺酰基-1h-苯并咪唑类化合物的盐的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
US6334997B1 (en) * 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
ATE372966T1 (de) * 1994-03-25 2007-09-15 Isotechnika Inc Verbesserung der effektivität von arzneimitteln duren deuterierung
US6884429B2 (en) * 1997-09-05 2005-04-26 Isotechnika International Inc. Medical devices incorporating deuterated rapamycin for controlled delivery thereof
NO309305B1 (no) * 1999-02-19 2001-01-15 Norsk Hydro As Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater
DE10123129A1 (de) * 2001-05-02 2002-11-14 Berolina Drug Dev Ab Svedala Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel
DE10162121A1 (de) * 2001-12-12 2003-06-18 Berolina Drug Dev Ab Svedala Deuterierte substituierte Pyrazolyl-Benzolsulfonamide sowie diese Verbindungen enthaltende Arzneimittel
EP1912947A1 (fr) * 2005-07-26 2008-04-23 Nycomed GmbH Pantoprazole substitue d'un point de vue isotopique

Also Published As

Publication number Publication date
WO2007012650A1 (fr) 2007-02-01
CN102134232B (zh) 2012-11-21
AU2006274036A2 (en) 2008-03-20
AR054584A1 (es) 2007-06-27
EP1910293A1 (fr) 2008-04-16
HK1125098A1 (en) 2009-07-31
CA2615670A1 (fr) 2007-02-01
CN101268051A (zh) 2008-09-17
NZ565078A (en) 2010-03-26
HK1160126A1 (en) 2012-08-10
KR20080037676A (ko) 2008-04-30
KR101358509B1 (ko) 2014-02-05
CN102134232A (zh) 2011-07-27
NO20080839L (no) 2008-02-18
BRPI0614039A2 (pt) 2011-03-09
ZA200800303B (en) 2009-01-28
CA2615670C (fr) 2015-01-20
TW200714596A (en) 2007-04-16
EA200800203A1 (ru) 2008-08-29
CN101268051B (zh) 2011-08-31
JP2009502871A (ja) 2009-01-29
EA016814B1 (ru) 2012-07-30
IL188773A0 (en) 2008-08-07
AU2006274036B2 (en) 2012-05-24
MX2008000901A (es) 2008-03-26
JP5448448B2 (ja) 2014-03-19
TWI394750B (zh) 2013-05-01
AU2006274036A1 (en) 2007-02-01

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees