IL186130A0 - 3,4,5-substituted piperidines as renin inhibitors - Google Patents

3,4,5-substituted piperidines as renin inhibitors

Info

Publication number
IL186130A0
IL186130A0 IL186130A IL18613007A IL186130A0 IL 186130 A0 IL186130 A0 IL 186130A0 IL 186130 A IL186130 A IL 186130A IL 18613007 A IL18613007 A IL 18613007A IL 186130 A0 IL186130 A0 IL 186130A0
Authority
IL
Israel
Prior art keywords
renin inhibitors
substituted piperidines
piperidines
substituted
renin
Prior art date
Application number
IL186130A
Other languages
English (en)
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of IL186130A0 publication Critical patent/IL186130A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL186130A 2005-03-31 2007-09-20 3,4,5-substituted piperidines as renin inhibitors IL186130A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66655605P 2005-03-31 2005-03-31
US75085305P 2005-12-16 2005-12-16
PCT/EP2006/061197 WO2006103277A2 (en) 2005-03-31 2006-03-30 2 , 4 , 5-substituted piperidines as renin inhibitors

Publications (1)

Publication Number Publication Date
IL186130A0 true IL186130A0 (en) 2008-01-20

Family

ID=36586065

Family Applications (2)

Application Number Title Priority Date Filing Date
IL186130A IL186130A0 (en) 2005-03-31 2007-09-20 3,4,5-substituted piperidines as renin inhibitors
IL189429A IL189429A0 (en) 2005-03-31 2008-02-11 3,4,5-substituted piperidines as renin inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL189429A IL189429A0 (en) 2005-03-31 2008-02-11 3,4,5-substituted piperidines as renin inhibitors

Country Status (13)

Country Link
US (2) US20100029628A1 (enExample)
EP (1) EP1863803B1 (enExample)
JP (2) JP2008534558A (enExample)
AR (2) AR055756A1 (enExample)
AT (1) ATE479681T1 (enExample)
BR (2) BRPI0621969A2 (enExample)
CA (1) CA2601702A1 (enExample)
DE (1) DE602006016573D1 (enExample)
IL (2) IL186130A0 (enExample)
PL (1) PL1863803T3 (enExample)
PT (1) PT1863803E (enExample)
TW (2) TW200833687A (enExample)
WO (1) WO2006103277A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8138340B2 (en) 2004-08-25 2012-03-20 Actelion Pharmaceuticals Ltd. Bicyclononene derivatives
AR055756A1 (es) * 2005-03-31 2007-09-05 Speedel Experimenta Ag Piperidinas sustituidas; procesos de preparacion y su uso como medicamentos
EP1893578A2 (en) 2005-05-27 2008-03-05 Actelion Pharmaceuticals Ltd. Novel piperidine carboxylic acid amide derivatives
GB0514203D0 (en) 2005-07-11 2005-08-17 Novartis Ag Organic compounds
RS52062B (sr) 2006-05-19 2012-06-30 Abbott Laboratories Cns aktivni azabiciklični alkanski derivati koji su supstituisani spojenim bicikloheterociklom
JP2009539806A (ja) * 2006-06-08 2009-11-19 シュペーデル・エクスペリメンタ・アーゲー ２，５−二置換ピペリジン
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
EP1958634A3 (en) * 2007-02-14 2008-09-24 Speedel Experimenta AG Substituted piperidines as inhibitors of beta-secretase, cathepsin D, plasmepsin II and/or HIV protease
AR069005A1 (es) * 2007-10-25 2009-12-23 Speedel Experimenta Ag Piperidinas 4,4-disustituidas
EP2215088A2 (en) * 2007-11-02 2010-08-11 Novartis AG 4,4-disubstituted piperdines as renin inhibitors
CA2708866A1 (en) 2007-12-19 2009-06-25 Hiroyuki Nakahira Bicyclic heterocyclic derivative
BRPI0907933A2 (pt) * 2008-02-08 2015-07-28 Novartis Ag Pepiridinas substituídas como inibidoras da renina
EA201001240A1 (ru) * 2008-02-08 2011-04-29 Новартис Аг Замещенные пиперидины в качестве ингибиторов ренина
KR101403311B1 (ko) 2008-05-05 2014-06-05 액테리온 파마슈티칼 리미티드 레닌 억제제로서의 3,4-치환된 피페리딘 유도체
EP2163245A1 (en) 2008-09-10 2010-03-17 Novartis Ag Renin inhibitors for the treatment of psoriasis
US8389731B2 (en) * 2009-05-15 2013-03-05 Northwestern University Chiral pyrrolidine core compounds en route to inhibitors of nitric oxide synthase
EP2447264A4 (en) 2009-06-24 2012-12-12 Dainippon Sumitomo Pharma Co N-SUBSTITUTED CYCLIC AMINO DERIVATIVE
WO2016112387A1 (en) * 2015-01-09 2016-07-14 J.W. Speaker Corporation Tracking and lighting systems and methods for a vehicle
DE102015013191A1 (de) * 2015-10-10 2017-04-13 Daimler Ag Verfahren zum Betrieb einer Leuchteinheit und Leuchteinheit

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE242213T1 (de) * 1995-09-07 2003-06-15 Hoffmann La Roche Neue 4-(oxyalkoxyphenyl)-3-oxy-piperidine zur behandlung von herz- und niereninsuffizienz
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US6197959B1 (en) * 1999-04-27 2001-03-06 Hoffmann-La Roche Inc. Piperidine derivatives
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
AR055756A1 (es) * 2005-03-31 2007-09-05 Speedel Experimenta Ag Piperidinas sustituidas; procesos de preparacion y su uso como medicamentos

Also Published As

Publication number Publication date
CA2601702A1 (en) 2006-10-05
BRPI0608758A2 (pt) 2009-07-07
BRPI0621969A2 (pt) 2011-07-19
WO2006103277A2 (en) 2006-10-05
JP2008534558A (ja) 2008-08-28
US7687495B2 (en) 2010-03-30
ATE479681T1 (de) 2010-09-15
DE602006016573D1 (de) 2010-10-14
JP2008201787A (ja) 2008-09-04
US20080171748A1 (en) 2008-07-17
WO2006103277A3 (en) 2006-12-28
AR055756A1 (es) 2007-09-05
EP1863803B1 (en) 2010-09-01
PT1863803E (pt) 2010-11-18
PL1863803T3 (pl) 2011-02-28
TW200833687A (en) 2008-08-16
TW200716622A (en) 2007-05-01
IL189429A0 (en) 2008-06-05
AR065188A2 (es) 2009-05-20
US20100029628A1 (en) 2010-02-04
EP1863803A2 (en) 2007-12-12

Similar Documents

Publication Publication Date Title
IL186130A0 (en) 3,4,5-substituted piperidines as renin inhibitors
IL192024A0 (en) 3,5-substituted piperidine compounds as renin inhibitors
IL186124A0 (en) 3,4,5-substituted piperidines as renin inhibitors
TWI369351B (en) 2,4-diamino-pyrimidines as aurora inhibitors
PL1833816T3 (pl) Podstawione piperydyny jako inhibitory reniny
ZA200804762B (en) 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors
ZA200707650B (en) Azolylacylguanidines as ß-secretase inhibitors
IL186117A0 (en) Substituted piperidines as renin inhibitors
IL192053A0 (en) 2-adamantylurea derivatives as selective 11??-hsd1 inhibitors
ZA200709051B (en) Heterocyclic compound
PL1919907T3 (pl) Związek heterocykliczny
IL195279A0 (en) 1,5-diphenylpyrazoles ii as hsp90 inhibitors
ZA200709691B (en) N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
IL180242A0 (en) Piperidine derivatives as renin inhibitors
IL189112A0 (en) NOVEL HETEROCYCLIC NF-kB INHIBITORS
AP2281A (en) Novel compounds.
IL195631A0 (en) 2,5-disubstituted piperidines
IL184677A0 (en) Substituted 1,1,1-trifluoro-3-[(benzyl)-
ZA200804956B (en) 3,5-substituted piperidine compounds as renin inhibitors
GB2429548B (en) Maintaining personal records
ZA200800142B (en) Heterocyclic compound
IL193483A0 (en) 4-amino-1,5-substituted 1,5 - dihydro - imidazol -2- ones
HK1110311A (en) 3,4,5-substituted piperidines as renin inhibitors
GB0516967D0 (en) Inhibitors
HK1121445A (en) 3, 5-substitued piperidine compounds as renin inhibitors