IL173260A0 - Improved glucose dehydrogenase polypeptides and related polynucleotides - Google Patents

Improved glucose dehydrogenase polypeptides and related polynucleotides

Info

Publication number
IL173260A0
IL173260A0 IL173260A IL17326006A IL173260A0 IL 173260 A0 IL173260 A0 IL 173260A0 IL 173260 A IL173260 A IL 173260A IL 17326006 A IL17326006 A IL 17326006A IL 173260 A0 IL173260 A0 IL 173260A0
Authority
IL
Israel
Prior art keywords
glucose dehydrogenase
related polynucleotides
improved glucose
dehydrogenase polypeptides
polypeptides
Prior art date
Application number
IL173260A
Other languages
English (en)
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of IL173260A0 publication Critical patent/IL173260A0/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL173260A 2003-08-11 2006-01-19 Improved glucose dehydrogenase polypeptides and related polynucleotides IL173260A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49430003P 2003-08-11 2003-08-11
US54565704P 2004-02-18 2004-02-18
PCT/US2004/026194 WO2005045016A2 (en) 2003-08-11 2004-08-11 Improved glucose dehydrogenase polypeptides and related polynucleotides

Publications (1)

Publication Number Publication Date
IL173260A0 true IL173260A0 (en) 2006-06-11

Family

ID=34576547

Family Applications (1)

Application Number Title Priority Date Filing Date
IL173260A IL173260A0 (en) 2003-08-11 2006-01-19 Improved glucose dehydrogenase polypeptides and related polynucleotides

Country Status (11)

Country Link
US (2) US7816111B2 (cg-RX-API-DMAC7.html)
EP (1) EP1660648B1 (cg-RX-API-DMAC7.html)
JP (1) JP2007502114A (cg-RX-API-DMAC7.html)
KR (1) KR20060064620A (cg-RX-API-DMAC7.html)
AU (1) AU2004288134B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0413492A (cg-RX-API-DMAC7.html)
CA (1) CA2535147A1 (cg-RX-API-DMAC7.html)
IL (1) IL173260A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA06001719A (cg-RX-API-DMAC7.html)
NO (1) NO20060543L (cg-RX-API-DMAC7.html)
WO (1) WO2005045016A2 (cg-RX-API-DMAC7.html)

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DE602007012130D1 (de) * 2006-11-14 2011-03-03 Toyo Boseki Modifizierte flavin-adenin-dinucleotid-abhängige glucose-dehydrogenase
JP2009034062A (ja) * 2007-08-03 2009-02-19 Kao Corp アルカリプロテアーゼ
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US8288141B2 (en) * 2008-08-27 2012-10-16 Codexis, Inc. Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
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HUE038800T2 (hu) 2011-04-13 2018-11-28 Codexis Inc Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására
US9139819B2 (en) 2011-11-18 2015-09-22 Codexis, Inc. Biocatalysts for the preparation of hydroxy substituted carbamates
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
HUE036947T2 (hu) 2012-05-11 2018-08-28 Codexis Inc Átalakított iminreduktázok és eljárások keton- és aminvegyületek reduktív aminálására
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
WO2014150633A1 (en) 2013-03-15 2014-09-25 Merck Sharp & Dohme Corp. Immobilized ketoreductases and process for making and using immobilized ketoreductase
CN105358687B (zh) 2013-04-17 2018-10-09 科学与工业研究委员会 在有效生产对映体富集的醇中用于酮的对映体选择性还原的设计师细胞及其应用
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JP6643987B2 (ja) 2013-11-13 2020-02-12 コデクシス， インコーポレイテッド ケトン化合物およびアミン化合物の還元的アミノ化のための操作されたイミンレダクターゼおよび方法
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EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
JP6522003B2 (ja) 2014-04-14 2019-05-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ フェナジニウムメディエーター
JP6659669B2 (ja) 2014-08-22 2020-03-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ レドックス指示薬
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US10696953B2 (en) 2015-02-10 2020-06-30 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
KR102372113B1 (ko) 2016-10-05 2022-03-07 에프. 호프만-라 로슈 아게 다중 분석물 진단 테스트 엘리먼트들을 위한 검출 시약들 및 전극 배열들, 그리고 그것을 사용하는 방법들
EP3339431A1 (en) * 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
MX2020006222A (es) * 2017-12-13 2020-08-31 Codexis Inc Polipeptidos de carboxiesterasa para acoplamiento de amidas.
ES2975412T3 (es) 2018-06-21 2024-07-05 Fis Fabbrica Italiana Sintetici Spa Proceso enzimático para la preparación de droxidopa
JP6480629B1 (ja) * 2018-08-07 2019-03-13 キッコーマン株式会社 グルコースデヒドロゲナーゼの組換え製造方法
WO2020123563A1 (en) * 2018-12-10 2020-06-18 The Regents Of The University Of California Engineered polypeptides that exhibit increased catalytic efficiency for unnatural cofactors and uses thereof
JP7677630B2 (ja) * 2019-05-01 2025-05-15 コデクシス， インコーポレイテッド 操作されたグルコースデヒドロゲナーゼ、ならびにケトンおよびアミン化合物の還元的アミノ化を行うための方法
EP4649143A1 (en) 2023-01-12 2025-11-19 Novartis AG Engineered ketoreductase polypeptides

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EP1660669A4 (en) * 2003-08-11 2008-10-01 Codexis Inc ENZYMATIC PROCEDURES FOR THE PREPARATION OF 4-SUBSTITUTED 3-HYDROXYBUTYLIC ACID DERIVATIVES AND OF VICINAL CYANO, HYDROXY-SUBSTITUTED CARBOXYLIC ACID ESTERS

Also Published As

Publication number Publication date
WO2005045016A3 (en) 2005-11-10
US7816111B2 (en) 2010-10-19
AU2004288134B2 (en) 2009-12-17
WO2005045016A2 (en) 2005-05-19
MXPA06001719A (es) 2006-05-19
US7939309B2 (en) 2011-05-10
EP1660648B1 (en) 2013-10-09
US20100304459A1 (en) 2010-12-02
NO20060543L (no) 2006-03-13
JP2007502114A (ja) 2007-02-08
CA2535147A1 (en) 2005-05-19
BRPI0413492A (pt) 2006-10-17
AU2004288134A1 (en) 2005-05-19
KR20060064620A (ko) 2006-06-13
US20050095619A1 (en) 2005-05-05
EP1660648A2 (en) 2006-05-31

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