IL166108A0 - Novel compounds pharmaceutical compositions containing same and methods of use for same - Google Patents
Novel compounds pharmaceutical compositions containing same and methods of use for sameInfo
- Publication number
- IL166108A0 IL166108A0 IL16610805A IL16610805A IL166108A0 IL 166108 A0 IL166108 A0 IL 166108A0 IL 16610805 A IL16610805 A IL 16610805A IL 16610805 A IL16610805 A IL 16610805A IL 166108 A0 IL166108 A0 IL 166108A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- methods
- pharmaceutical compositions
- compositions containing
- novel compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39458502P | 2002-07-09 | 2002-07-09 | |
| PCT/US2003/021700 WO2004005277A1 (en) | 2002-07-09 | 2003-07-09 | Novel compunds, pharmaceutical compositions containing same, and methods of use for same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166108A0 true IL166108A0 (en) | 2006-01-15 |
Family
ID=30115739
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16610805A IL166108A0 (en) | 2002-07-09 | 2005-01-03 | Novel compounds pharmaceutical compositions containing same and methods of use for same |
| IL190218A IL190218A0 (en) | 2002-07-09 | 2008-03-17 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL190218A IL190218A0 (en) | 2002-07-09 | 2008-03-17 | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7649012B2 (enExample) |
| EP (3) | EP1539730A4 (enExample) |
| JP (3) | JP2005533835A (enExample) |
| KR (1) | KR101087559B1 (enExample) |
| CN (2) | CN101602756B (enExample) |
| AU (1) | AU2003265267B2 (enExample) |
| BR (1) | BRPI0312649A2 (enExample) |
| CA (2) | CA2491802C (enExample) |
| EA (1) | EA013371B1 (enExample) |
| IL (2) | IL166108A0 (enExample) |
| MX (1) | MXPA05000365A (enExample) |
| SG (1) | SG169236A1 (enExample) |
| WO (1) | WO2004005277A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04007556A (es) | 2002-02-08 | 2005-12-05 | Univ Johns Hopkins Med | Estimulacion de cpt-1 como medio para reducir peso. |
| US20060135568A1 (en) * | 2002-07-09 | 2006-06-22 | Townsend Craig A | Methods of treating microbial infections in humans and animals |
| US7649012B2 (en) * | 2002-07-09 | 2010-01-19 | Fasgen, Inc. | Compounds, pharmaceutical compositions containing same, and methods of use for same |
| CN101022792A (zh) * | 2004-05-26 | 2007-08-22 | 法斯根有限责任公司 | 新化合物、包含该化合物的药物组合物及该化合物的应用方法 |
| JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
| US20100168176A1 (en) * | 2006-11-08 | 2010-07-01 | Fasgen Llc | Novel compounds, pharmaceutical compositions containing same, and methods of use for same |
| WO2008059214A1 (en) * | 2006-11-13 | 2008-05-22 | Astrazeneca Ab | Bisamlde derivatives and use thereof as fatty acid synthase inhibitors |
| EP2285215A4 (en) * | 2008-06-02 | 2012-04-04 | Fasgen Inc | NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREFOR AND METHOD OF USE THEREOF |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| WO2010118324A2 (en) | 2009-04-09 | 2010-10-14 | Nuclea Biotechnologies, LLC | Antibodies against fatty acid synthase |
| US9149445B2 (en) | 2009-07-27 | 2015-10-06 | The Trustees Of Princeton University | Inhibition of glycerol-3-phosphate acyltransferase (GPAT) and associated enzymes for treatment of viral infections |
| SG178880A1 (en) | 2009-08-26 | 2012-04-27 | Sanofi Sa | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
| US8450350B2 (en) | 2010-05-05 | 2013-05-28 | Infinity Pharmaceuticals, Inc. | Triazoles as inhibitors of fatty acid synthase |
| CA2798330A1 (en) | 2010-05-05 | 2011-11-10 | Infinity Pharmaceuticals, Inc. | Tetrazolones as inhibitors of fatty acid synthase |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683698B1 (de) | 2011-03-08 | 2017-10-04 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8809324B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8846666B2 (en) | 2011-03-08 | 2014-09-30 | Sanofi | Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| WO2012135027A2 (en) * | 2011-03-25 | 2012-10-04 | The Research Foundation Of State University Of New York | Thiolactone antibiotics |
| EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| JP6228198B2 (ja) * | 2012-06-25 | 2017-11-08 | トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 異常な脂質生合成シグナル伝達を有するがんを処置するための組成物および方法 |
| WO2014039769A1 (en) * | 2012-09-07 | 2014-03-13 | Janssen Pharmaceutica Nv | Imidazolin-5-one derivatives useful as fatty acid snthase (fasn) inhibitors for|the treatment of cancer |
| MX364895B (es) | 2013-03-13 | 2019-05-10 | Forma Therapeutics Inc | Nuevos compuestos y composiciones para la inhibicion de fasn. |
| CA2968288A1 (en) | 2014-11-20 | 2016-05-26 | Vib Vzw | Means and methods for treatment of early-onset parkinson's disease |
| CN113382633A (zh) | 2018-10-29 | 2021-09-10 | 福马治疗股份有限公司 | (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式 |
| CN114480521B (zh) * | 2020-11-13 | 2024-07-26 | 中国科学院青岛生物能源与过程研究所 | 一种三氮菌素c的制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3496187A (en) * | 1967-03-20 | 1970-02-17 | American Home Prod | N-(heterocyclyl)aconamides |
| US3472878A (en) * | 1969-01-27 | 1969-10-14 | American Home Prod | N-(hydroxyaryl)aconamides |
| JPS5859920A (ja) | 1981-10-05 | 1983-04-09 | Chugai Pharmaceut Co Ltd | 生体防禦能賦活剤 |
| US4565699A (en) * | 1983-07-18 | 1986-01-21 | The Upjohn Company | Composition of matter and process |
| US4720503A (en) * | 1985-08-02 | 1988-01-19 | Merck & Co., Inc. | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
| CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
| US4753871A (en) * | 1986-12-12 | 1988-06-28 | Eastman Kodak Company | Cyan dye-forming couplers and photographic materials containing same |
| AU1044088A (en) * | 1986-12-17 | 1988-07-15 | Nippon Soda Co., Ltd. | Heterocyclic compounds having triketo skeleton |
| US5759837A (en) | 1989-01-17 | 1998-06-02 | John Hopkins University | Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway |
| US5665874A (en) * | 1989-01-17 | 1997-09-09 | John Hopkins University | Cancer related antigen |
| US5759791A (en) * | 1989-01-17 | 1998-06-02 | The Johns Hopkins University | Cancer related antigen |
| US5679801A (en) * | 1991-04-12 | 1997-10-21 | American Home Products Corporation | Tetronic and thiotetronic acid derivatives as phospholipase A2 inhibitors |
| US5614551A (en) | 1994-01-24 | 1997-03-25 | The Johns Hopkins University | Inhibitors of fatty acid synthesis as antimicrobial agents |
| MX9708597A (es) * | 1995-05-09 | 1998-02-28 | Bayer Ag | Cetoenoles alquil-dihalogenofenil substituidos como pesticidas y herbicidas. |
| US5981575A (en) | 1996-11-15 | 1999-11-09 | Johns Hopkins University, The | Inhibition of fatty acid synthase as a means to reduce adipocyte mass |
| JPH10212284A (ja) * | 1996-11-27 | 1998-08-11 | Sagami Chem Res Center | テトロン酸−３−カルボン酸誘導体、その製造方法、製造中間体、抗がん剤、及び蛋白脱リン酸化酵素阻害剤 |
| US6391912B1 (en) * | 1996-12-12 | 2002-05-21 | Bayer Aktiengesellschaft | Substituted phenylketoenols |
| CO4970714A1 (es) * | 1997-09-05 | 2000-11-07 | Boehringer Mannheim Gmbh | Derivados ureido y tioureido de 4-amino-2(5h)-furanonas y 4-amino-2(5h) tiofenonas como agentes antitumorales |
| HN2000000051A (es) * | 1999-05-19 | 2001-02-02 | Pfizer Prod Inc | Derivados heterociclicos utiles como agentes anticancerosos |
| IT1315267B1 (it) * | 1999-12-23 | 2003-02-03 | Novuspharma Spa | Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale |
| GB0000131D0 (en) * | 2000-01-06 | 2000-02-23 | Univ Cardiff | Thiolactomycin analogues,compositions containing the same and uses thereof |
| US6376682B1 (en) * | 2000-02-01 | 2002-04-23 | Takama System, Ltd. | Compound with α-glucosidase inhibiting action and method for producing the same |
| JP2004528341A (ja) | 2001-05-02 | 2004-09-16 | ニューヨーク・ユニバーシティ | 脂肪酸合成酵素の阻害による色素形成の阻害 |
| MXPA04007556A (es) * | 2002-02-08 | 2005-12-05 | Univ Johns Hopkins Med | Estimulacion de cpt-1 como medio para reducir peso. |
| US20060135568A1 (en) | 2002-07-09 | 2006-06-22 | Townsend Craig A | Methods of treating microbial infections in humans and animals |
| US7649012B2 (en) * | 2002-07-09 | 2010-01-19 | Fasgen, Inc. | Compounds, pharmaceutical compositions containing same, and methods of use for same |
| US9690894B1 (en) | 2015-11-02 | 2017-06-27 | Altera Corporation | Safety features for high level design |
-
2003
- 2003-07-09 US US10/520,505 patent/US7649012B2/en not_active Expired - Fee Related
- 2003-07-09 KR KR1020057000382A patent/KR101087559B1/ko not_active Expired - Fee Related
- 2003-07-09 CN CN200910203849.8A patent/CN101602756B/zh not_active Expired - Fee Related
- 2003-07-09 AU AU2003265267A patent/AU2003265267B2/en not_active Ceased
- 2003-07-09 JP JP2004520132A patent/JP2005533835A/ja active Pending
- 2003-07-09 CA CA2491802A patent/CA2491802C/en not_active Expired - Fee Related
- 2003-07-09 EA EA200500178A patent/EA013371B1/ru not_active IP Right Cessation
- 2003-07-09 EP EP03763470A patent/EP1539730A4/en not_active Withdrawn
- 2003-07-09 WO PCT/US2003/021700 patent/WO2004005277A1/en not_active Ceased
- 2003-07-09 EP EP11164123A patent/EP2386550A1/en not_active Withdrawn
- 2003-07-09 CA CA2767092A patent/CA2767092C/en not_active Expired - Fee Related
- 2003-07-09 CN CNB038185563A patent/CN100513404C/zh not_active Expired - Fee Related
- 2003-07-09 BR BRPI0312649A patent/BRPI0312649A2/pt not_active IP Right Cessation
- 2003-07-09 SG SG200806632-6A patent/SG169236A1/en unknown
- 2003-07-09 MX MXPA05000365A patent/MXPA05000365A/es active IP Right Grant
- 2003-07-09 EP EP11164126A patent/EP2386551A1/en not_active Withdrawn
-
2005
- 2005-01-03 IL IL16610805A patent/IL166108A0/xx unknown
-
2008
- 2008-03-17 IL IL190218A patent/IL190218A0/en unknown
-
2010
- 2010-01-13 US US12/686,691 patent/US20100120901A1/en not_active Abandoned
- 2010-10-08 JP JP2010228956A patent/JP2011037881A/ja active Pending
-
2013
- 2013-06-04 JP JP2013117677A patent/JP2013189464A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1539730A4 (en) | 2007-03-28 |
| CN101602756A (zh) | 2009-12-16 |
| CN101602756B (zh) | 2014-11-12 |
| KR20060002007A (ko) | 2006-01-06 |
| SG169236A1 (en) | 2011-03-30 |
| MXPA05000365A (es) | 2005-09-20 |
| IL190218A0 (en) | 2008-11-03 |
| EA013371B1 (ru) | 2010-04-30 |
| JP2011037881A (ja) | 2011-02-24 |
| AU2003265267A1 (en) | 2004-01-23 |
| US7649012B2 (en) | 2010-01-19 |
| EP2386551A1 (en) | 2011-11-16 |
| CN1675192A (zh) | 2005-09-28 |
| CA2491802A1 (en) | 2004-01-15 |
| JP2005533835A (ja) | 2005-11-10 |
| CA2767092C (en) | 2013-10-15 |
| WO2004005277A1 (en) | 2004-01-15 |
| KR101087559B1 (ko) | 2011-11-29 |
| CA2767092A1 (en) | 2004-01-15 |
| EP2386550A1 (en) | 2011-11-16 |
| US20060247302A1 (en) | 2006-11-02 |
| CA2491802C (en) | 2012-04-10 |
| US20100120901A1 (en) | 2010-05-13 |
| HK1083835A1 (zh) | 2006-07-14 |
| BRPI0312649A2 (pt) | 2017-05-16 |
| CN100513404C (zh) | 2009-07-15 |
| JP2013189464A (ja) | 2013-09-26 |
| EA200500178A1 (ru) | 2006-02-24 |
| EP1539730A1 (en) | 2005-06-15 |
| AU2003265267B2 (en) | 2010-03-11 |
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