IL165534A0 - Reduction of gelatin cross linking - Google Patents
Reduction of gelatin cross linkingInfo
- Publication number
- IL165534A0 IL165534A0 IL16553404A IL16553404A IL165534A0 IL 165534 A0 IL165534 A0 IL 165534A0 IL 16553404 A IL16553404 A IL 16553404A IL 16553404 A IL16553404 A IL 16553404A IL 165534 A0 IL165534 A0 IL 165534A0
- Authority
- IL
- Israel
- Prior art keywords
- reduction
- cross linking
- gelatin cross
- gelatin
- linking
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38611502P | 2002-06-05 | 2002-06-05 | |
| PCT/US2003/017620 WO2003103582A2 (en) | 2002-06-05 | 2003-06-05 | Reduction of gelatin cross-linking |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL165534A0 true IL165534A0 (en) | 2006-01-15 |
Family
ID=29736134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16553404A IL165534A0 (en) | 2002-06-05 | 2004-12-02 | Reduction of gelatin cross linking |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8895059B2 (de) |
| EP (1) | EP1549299B1 (de) |
| AU (1) | AU2003240536B2 (de) |
| ES (1) | ES2524000T3 (de) |
| IL (1) | IL165534A0 (de) |
| NZ (1) | NZ537022A (de) |
| WO (1) | WO2003103582A2 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
| US7485323B2 (en) | 2005-05-31 | 2009-02-03 | Gelita Ag | Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions |
| SI1906938T1 (sl) | 2005-07-26 | 2011-02-28 | Nicox Sa | Farmacevtska formulacija nitrooksiderivatov od NSAID |
| PE20081482A1 (es) * | 2006-12-20 | 2008-12-23 | Novartis Ag | Capsulas de gelatina que contienen un acido |
| EP3187182B1 (de) | 2008-09-02 | 2021-03-03 | Amarin Pharmaceuticals Ireland Limited | Pharmazeutische zusammensetzungen mit eicosapentaensäure und nikotinsäure und verfahren zur verwendung davon |
| CN107233337A (zh) | 2009-04-29 | 2017-10-10 | 阿马里纳药物爱尔兰有限公司 | 含有epa和心血管剂的药物组合物以及使用其的方法 |
| MX377553B (es) | 2009-04-29 | 2025-03-10 | Amarin Pharma Inc | Composicion farmaceutica estable y metodos de uso de la misma. |
| BRPI1011883A2 (pt) | 2009-06-15 | 2016-09-13 | Amarin Pharma Inc | uso de composições para redução de triglicerídeos sem elevar os níveis de o ldl-c em um paciente sob o tratamento concomitante com estatina |
| CA2772144A1 (en) * | 2009-09-04 | 2011-03-10 | Dominique Nicolas Cade | Scented capsules |
| NZ599061A (en) | 2009-09-23 | 2014-05-30 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same |
| NZ744990A (en) | 2010-11-29 | 2019-10-25 | Amarin Pharmaceuticals Ie Ltd | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
| WO2013070735A1 (en) | 2011-11-07 | 2013-05-16 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
| EP2800469B1 (de) | 2012-01-06 | 2021-08-25 | Amarin Pharmaceuticals Ireland Limited | Zusammensetzungen und verfahren zur senkung der konzentration an hochsensitivem c-reaktiven protein (hs-crp) bei einer person |
| US9603826B2 (en) | 2012-06-29 | 2017-03-28 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of a cardiovascular event in a subject on statin therapy |
| WO2014074552A2 (en) | 2012-11-06 | 2014-05-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy |
| US9814733B2 (en) | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
| US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
| US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
| US9624492B2 (en) | 2013-02-13 | 2017-04-18 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof |
| US9662307B2 (en) | 2013-02-19 | 2017-05-30 | The Regents Of The University Of Colorado | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof |
| US9283201B2 (en) | 2013-03-14 | 2016-03-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating or preventing obesity in a subject in need thereof |
| US20140271841A1 (en) | 2013-03-15 | 2014-09-18 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin |
| US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
| KR101833280B1 (ko) * | 2013-06-28 | 2018-02-28 | 한미약품 주식회사 | 두타스테라이드를 포함하는 경구용 연질 캡슐 제형 |
| US20150065572A1 (en) | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
| US9585859B2 (en) | 2013-10-10 | 2017-03-07 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy |
| US10561631B2 (en) | 2014-06-11 | 2020-02-18 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing RLP-C |
| WO2015195662A1 (en) | 2014-06-16 | 2015-12-23 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids |
| US10406130B2 (en) | 2016-03-15 | 2019-09-10 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
| NL2017219B1 (en) | 2016-07-22 | 2018-01-30 | Rousselot B V | Low cross-linking gelatine |
| JP6843376B2 (ja) * | 2016-10-14 | 2021-03-17 | アピ株式会社 | カプセル皮膜組成物及びカプセル |
| JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
| US10966951B2 (en) | 2017-05-19 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject having reduced kidney function |
| WO2019036471A1 (en) | 2017-08-14 | 2019-02-21 | Axcella Health Inc. | AMINO ACIDS BRANCHED FOR THE TREATMENT OF LIVER DISEASE |
| US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
| EP3810123A1 (de) | 2018-06-20 | 2021-04-28 | Axcella Health Inc. | Zusammensetzungen und verfahren zur behandlung von fettinfiltration in muskeln |
| MA50490A (fr) | 2018-09-24 | 2020-09-02 | Amarin Pharmaceuticals Ie Ltd | Procédés de réduction du risque d'événements cardiovasculaires chez un sujet |
| CA3160676A1 (en) | 2019-11-12 | 2021-05-20 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter |
| CN111840247B (zh) * | 2020-07-23 | 2022-06-07 | 青岛益青生物科技股份有限公司 | 一种具有抗交联作用的明胶空心胶囊及其制备方法 |
| US11986452B2 (en) | 2021-04-21 | 2024-05-21 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of heart failure |
| CN120643526B (zh) * | 2025-05-23 | 2025-12-09 | 安徽威尔曼制药有限公司 | 一种二十碳五烯酸乙酯软胶囊及制备工艺 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2467715A (en) | 1946-03-08 | 1949-04-19 | Nat Starch Products Inc | Manufacture of animal glue jellies |
| US2519487A (en) | 1947-07-02 | 1950-08-22 | Merck & Co Inc | Multivitamin preparation |
| US3456051A (en) | 1965-10-20 | 1969-07-15 | Takeda Chemical Industries Ltd | Soft gelatin sheet for soft gelatin capsule |
| US6090414A (en) * | 1970-05-20 | 2000-07-18 | Life Science Labs, Inc. | Method and composition to reduce cancer incidence |
| US4255413A (en) | 1979-10-01 | 1981-03-10 | Smithkline Corporation | Gelatin capsule dosage unit containing triamterene |
| DD225426A1 (de) | 1984-06-22 | 1985-07-31 | Jenapharm Veb | Verfahren zur herstellung stabiler gelantinezubereitungen |
| JPS63215641A (ja) * | 1987-03-05 | 1988-09-08 | Toyo Jozo Co Ltd | ゼラチン皮膜組成物 |
| FR2617047B1 (fr) | 1987-06-23 | 1991-05-10 | Sanofi Sa | Composition de gelatine resistant au tannage, capsules a base de cette composition et leur application pharmaceutique, notamment au fenofibrate |
| DD295765A5 (de) | 1988-07-18 | 1991-11-14 | Arzneimittelwerk Dresden Gmbh,De | Verfahren zur herstellung galenischer formulierungen fuer hydrophobe bzw. lipophile peptidwirkstoffe |
| US5186944A (en) | 1989-02-15 | 1993-02-16 | Eimei Company Ltd. | Therapeutic medicament for thrombosis |
| DE4201179A1 (de) | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
| JPH06321541A (ja) | 1993-05-18 | 1994-11-22 | Etsuro Kato | ジルコニア単分散球状超微粒子粉末の製造方法 |
| DE69535127T2 (de) * | 1994-03-18 | 2007-02-15 | Supernus Pharmaceuticals, Inc. | Emulgierte arzneistoffabgabesysteme |
| US5620704A (en) * | 1994-11-07 | 1997-04-15 | Warner-Lambert Company | Process for stabilizing gelatin products |
| CZ288631B6 (cs) * | 1996-01-18 | 2001-08-15 | Galena, A. S. | Léčivé přípravky s obsahem cyklosporinu |
| AU1925697A (en) * | 1996-03-12 | 1997-10-01 | Novartis Ag | Filled gelatin capsules having a reduced degree of cross-linking |
| JP2000002682A (ja) | 1998-06-12 | 2000-01-07 | Horiba Ltd | ガス分析装置 |
| US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| US6685961B1 (en) * | 2000-10-24 | 2004-02-03 | Banner Pharmacaps, Inc. | Colored gelatin-based formulations and method |
| JP2005538102A (ja) | 2002-07-31 | 2005-12-15 | ファルマシア・コーポレーション | 低下された架橋を示すゼラチンカプセル |
-
2003
- 2003-06-05 ES ES03731548.8T patent/ES2524000T3/es not_active Expired - Lifetime
- 2003-06-05 NZ NZ537022A patent/NZ537022A/en unknown
- 2003-06-05 US US10/516,904 patent/US8895059B2/en not_active Expired - Fee Related
- 2003-06-05 WO PCT/US2003/017620 patent/WO2003103582A2/en not_active Ceased
- 2003-06-05 AU AU2003240536A patent/AU2003240536B2/en not_active Ceased
- 2003-06-05 EP EP03731548.8A patent/EP1549299B1/de not_active Expired - Lifetime
-
2004
- 2004-12-02 IL IL16553404A patent/IL165534A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1549299B1 (de) | 2014-08-20 |
| WO2003103582A3 (en) | 2004-07-29 |
| US8895059B2 (en) | 2014-11-25 |
| EP1549299A2 (de) | 2005-07-06 |
| AU2003240536A1 (en) | 2003-12-22 |
| WO2003103582A2 (en) | 2003-12-18 |
| ES2524000T3 (es) | 2014-12-03 |
| US20110097398A1 (en) | 2011-04-28 |
| NZ537022A (en) | 2006-10-27 |
| AU2003240536B2 (en) | 2007-11-15 |
| EP1549299A4 (de) | 2010-12-15 |
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