IL162171A0 - Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof - Google Patents

Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Info

Publication number
IL162171A0
IL162171A0 IL16217102A IL16217102A IL162171A0 IL 162171 A0 IL162171 A0 IL 162171A0 IL 16217102 A IL16217102 A IL 16217102A IL 16217102 A IL16217102 A IL 16217102A IL 162171 A0 IL162171 A0 IL 162171A0
Authority
IL
Israel
Prior art keywords
venlafaxine
preparing
processes
crystalline
base
Prior art date
Application number
IL16217102A
Other languages
English (en)
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL162171A0 publication Critical patent/IL162171A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL16217102A 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof IL162171A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/000,428 US20020183553A1 (en) 2000-10-19 2001-11-30 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
PCT/US2002/037268 WO2003048082A2 (en) 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Publications (1)

Publication Number Publication Date
IL162171A0 true IL162171A0 (en) 2005-11-20

Family

ID=21691493

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16217102A IL162171A0 (en) 2001-11-30 2002-11-20 Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof

Country Status (16)

Country Link
US (4) US20020183553A1 (xx)
EP (1) EP1474379A4 (xx)
JP (1) JP2005511668A (xx)
KR (1) KR20040068163A (xx)
CN (2) CN1617848A (xx)
AU (1) AU2002365874A1 (xx)
CA (1) CA2468728A1 (xx)
HR (1) HRP20040565A2 (xx)
HU (1) HUP0700037A2 (xx)
IL (1) IL162171A0 (xx)
IS (1) IS7289A (xx)
MX (1) MXPA04005193A (xx)
NO (1) NO20042732L (xx)
PL (1) PL374273A1 (xx)
WO (1) WO2003048082A2 (xx)
ZA (1) ZA200404080B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1620420A (zh) * 2000-10-19 2005-05-25 特瓦制药工业有限公司 结晶文拉法辛碱和新的文拉法辛盐酸盐多晶型物及其制备方法
CA2426393C (en) * 2000-10-31 2012-05-29 Ciba Specialty Chemicals Holding Inc. Crystalline forms of venlafaxine hydrochloride
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)
CA2467593A1 (en) * 2001-12-05 2003-06-19 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
AU2003226748A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Compositions of venlafaxine base
DE10359154A1 (de) * 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
WO2007047972A2 (en) * 2005-10-19 2007-04-26 Teva Pharmaceutical Industries Ltd. Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
SI1954669T1 (sl) * 2005-12-01 2016-01-29 Auspex Pharmaceuticals, Inc. Substituirani fenetilamini s serotoninergično in / ali noradrenalinsko aktivnostjo
DK2125698T3 (en) * 2007-03-15 2016-11-07 Auspex Pharmaceuticals Inc Deuterated d9-VENLAFAXINE
CN101279926A (zh) * 2008-05-22 2008-10-08 杭州盛美医药科技开发有限公司 盐酸文拉法辛晶型FormⅠ的制备方法
BR112015005894B1 (pt) 2012-09-18 2022-03-29 Auspex Pharmaceuticals, Inc Composto, composição farmacêutica, método para tratar um distúrbio mediado por vmat2 e formulação farmacêutica de liberação prolongada
TWI665190B (zh) 2013-11-15 2019-07-11 阿克比治療有限公司 ｛［５－（３－氯苯基）－３－羥基吡啶－２－羰基］胺基｝乙酸之固體型式，其組合物及用途
CN114796209A (zh) 2015-03-06 2022-07-29 奥斯拜客斯制药有限公司 氘代丁苯那嗪或包含氘代丁苯那嗪的组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US4611078A (en) * 1983-10-26 1986-09-09 American Home Products Corporation Substituted phenylacetonitriles
US6197828B1 (en) * 1998-12-01 2001-03-06 Sepracor, Inc. Derivatives of (+)-venlafaxine and methods of preparing and using the same
CN1620420A (zh) * 2000-10-19 2005-05-25 特瓦制药工业有限公司 结晶文拉法辛碱和新的文拉法辛盐酸盐多晶型物及其制备方法
CA2426393C (en) 2000-10-31 2012-05-29 Ciba Specialty Chemicals Holding Inc. Crystalline forms of venlafaxine hydrochloride
AU2001235970A1 (en) 2000-12-07 2002-06-18 Dr. Reddy's Research Foundation Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
DE60136263D1 (de) * 2001-04-10 2008-12-04 Alembic Ltd Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol
CA2467593A1 (en) * 2001-12-05 2003-06-19 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
WO2003050074A1 (en) * 2001-12-13 2003-06-19 Cadila Healthcare Limited Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof

Also Published As

Publication number Publication date
EP1474379A2 (en) 2004-11-10
KR20040068163A (ko) 2004-07-30
NO20042732L (no) 2004-06-29
HRP20040565A2 (en) 2005-08-31
US6924393B2 (en) 2005-08-02
CN1617848A (zh) 2005-05-18
IS7289A (is) 2004-05-27
US20040220278A1 (en) 2004-11-04
EP1474379A4 (en) 2006-06-07
WO2003048082A2 (en) 2003-06-12
US20020183553A1 (en) 2002-12-05
HUP0700037A2 (en) 2007-05-02
JP2005511668A (ja) 2005-04-28
ZA200404080B (en) 2007-12-27
US20050049304A1 (en) 2005-03-03
AU2002365874A1 (en) 2003-06-17
WO2003048082A3 (en) 2004-08-26
CN101219962A (zh) 2008-07-16
CA2468728A1 (en) 2003-06-12
MXPA04005193A (es) 2005-02-22
PL374273A1 (en) 2005-10-03
US20080167498A1 (en) 2008-07-10

Similar Documents

Publication Publication Date Title
IL196287A0 (en) Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride and processes for preparing thereof
HUP0204010A3 (en) Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and their use
IL162171A0 (en) Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
AP2004002989A0 (en) Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation.
AU2003253188A8 (en) Novel processes and intermediates for preparing triazolo-pyridines
IL159994A0 (en) Process for preparing 4-aminodiphenylamine
AU1234002A (en) Crystalline forms of venlafaxine hydrochloride
HUP0400299A2 (en) Polymorphs of fexofenadine hydrochloride
IL162255A0 (en) Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
EP1406855A4 (en) NOVEL PROCESS FOR THE PREPARATION OF RAC-BICALUTAMIDE AND INTERMEDIATE PRODUCTS THEREOF
EP1497272A4 (en) METHOD FOR PRODUCING AMIN STEREO ISOMERS
AU2002247945A1 (en) Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof
AU2001235970A1 (en) Novel crystalline polymorphic forms of venlafaxine hydrochloride and a process for their preparation
PL2181982T3 (pl) Sposób wytwarzania chlorowodorku wenlafaksyny w formie I
PL376832A1 (pl) Sposób wytwarzania polimorficznej postaci chlorowodorku sertraliny
AU2003244886A1 (en) Process for preparing tramadol hydrochloride and/or tramadol momohydrate
PL372137A1 (en) A novel polymorph of sertraline hydrochloride and composition containing thereof, novel methods for preparation of sertraline hydrochloride polymorphs and amorphous form
AU2002308095A1 (en) Process for preparing sertraline hydrochloride polymorphic form ii
AU2002347399A1 (en) Venlafaxine hydrochloride polymorphs
HU0104872D0 (en) New polymorphic forms of venlafaxine
IL161816A0 (en) Polymorphs of fexofenadine base