DE60136263D1 - Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol - Google Patents

Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol

Info

Publication number
DE60136263D1
DE60136263D1 DE60136263T DE60136263T DE60136263D1 DE 60136263 D1 DE60136263 D1 DE 60136263D1 DE 60136263 T DE60136263 T DE 60136263T DE 60136263 T DE60136263 T DE 60136263T DE 60136263 D1 DE60136263 D1 DE 60136263D1
Authority
DE
Germany
Prior art keywords
cyclohexanol
methoxyphenyl
ethyl
preparation
dimethylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60136263T
Other languages
English (en)
Inventor
Dhiraj Mohansinh Rathod
Srinivasan Rengaraju
Gharpure
Nishant Mahendra Patel
Mandar Manohar Deoahar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alembic Ltd
Original Assignee
Alembic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alembic Ltd filed Critical Alembic Ltd
Application granted granted Critical
Publication of DE60136263D1 publication Critical patent/DE60136263D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60136263T 2001-04-10 2001-04-10 Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol Expired - Fee Related DE60136263D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01303347A EP1249447B1 (de) 2001-04-10 2001-04-10 Zwischenprodukt zur Herstellung von 1-[2-Dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol

Publications (1)

Publication Number Publication Date
DE60136263D1 true DE60136263D1 (de) 2008-12-04

Family

ID=8181889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60136263T Expired - Fee Related DE60136263D1 (de) 2001-04-10 2001-04-10 Zwischenprodukt zur Herstellung von 1-Ä2-Dimethylamino-1-(4-methoxyphenyl)-ethylÜ-cyclohexanol

Country Status (5)

Country Link
US (1) US6756502B2 (de)
EP (1) EP1249447B1 (de)
AT (1) ATE411986T1 (de)
CA (1) CA2381334A1 (de)
DE (1) DE60136263D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020183553A1 (en) * 2000-10-19 2002-12-05 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof
US20050033088A1 (en) * 2003-06-06 2005-02-10 Dr. Reddy's Laboratories Limited Process for the preparation of phenethylamine derivative, an intermediate of Venlafaxine hydrochloride
WO2007047972A2 (en) * 2005-10-19 2007-04-26 Teva Pharmaceutical Industries Ltd. Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
EP2746275A1 (de) 2012-12-19 2014-06-25 Basf Se Neue substituierte Triazole und Imidazole sowie ihre Verwendung als Fungizide
IN2013DE03197A (de) 2013-10-29 2015-05-01 Council Scient Ind Res
CN112742367B (zh) * 2019-10-29 2023-07-11 中国石油化工股份有限公司 一种催化氧化环烷烃的方法
CN113402400B (zh) * 2021-04-29 2023-12-08 深圳市新浩瑞医药科技有限公司 一种去甲文拉法辛的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
IE56324B1 (en) 1982-12-13 1991-06-19 American Home Prod Phenethylamine derivatives and intermediates therefor
GB8902209D0 (en) 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates

Also Published As

Publication number Publication date
US20030195376A1 (en) 2003-10-16
ATE411986T1 (de) 2008-11-15
US6756502B2 (en) 2004-06-29
CA2381334A1 (en) 2002-10-10
EP1249447B1 (de) 2008-10-22
EP1249447A1 (de) 2002-10-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee