IL161970A0 - Amorphous and crystalline forms of losartion potassium and process fortheir preparation - Google Patents

Amorphous and crystalline forms of losartion potassium and process fortheir preparation

Info

Publication number
IL161970A0
IL161970A0 IL16197002A IL16197002A IL161970A0 IL 161970 A0 IL161970 A0 IL 161970A0 IL 16197002 A IL16197002 A IL 16197002A IL 16197002 A IL16197002 A IL 16197002A IL 161970 A0 IL161970 A0 IL 161970A0
Authority
IL
Israel
Prior art keywords
losartion
amorphous
potassium
crystalline forms
fortheir preparation
Prior art date
Application number
IL16197002A
Other languages
English (en)
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of IL161970A0 publication Critical patent/IL161970A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL16197002A 2001-11-14 2002-11-13 Amorphous and crystalline forms of losartion potassium and process fortheir preparation IL161970A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33303401P 2001-11-14 2001-11-14
US40127802P 2002-08-05 2002-08-05
PCT/US2002/036550 WO2003048135A1 (en) 2001-11-14 2002-11-13 Amorphous and crystalline forms of losartan potassium and process for their preparation

Publications (1)

Publication Number Publication Date
IL161970A0 true IL161970A0 (en) 2005-11-20

Family

ID=26988524

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16197002A IL161970A0 (en) 2001-11-14 2002-11-13 Amorphous and crystalline forms of losartion potassium and process fortheir preparation

Country Status (16)

Country Link
US (2) US7332612B2 (is)
EP (1) EP1458693A4 (is)
JP (2) JP2006504618A (is)
KR (1) KR20050044450A (is)
CN (1) CN1612866A (is)
AU (1) AU2002360386A1 (is)
CA (2) CA2465597A1 (is)
ES (1) ES2234451T1 (is)
HR (1) HRP20040510A2 (is)
HU (1) HUP0501067A2 (is)
IL (1) IL161970A0 (is)
IS (1) IS7262A (is)
MX (1) MXPA04004657A (is)
NO (1) NO20042434L (is)
PL (1) PL374442A1 (is)
WO (1) WO2003048135A1 (is)

Families Citing this family (91)

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IL154370A0 (en) * 2003-02-10 2003-09-17 Chemagis Ltd Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same
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AU2003209669A1 (en) * 2003-02-25 2004-09-17 Hetero Drugs Limited Amorphous form of losartan potassium
WO2004076442A1 (en) * 2003-02-28 2004-09-10 Ranbaxy Laboratories Limited Polymorphs of losartan
US7345071B2 (en) 2003-05-07 2008-03-18 Ipca Laboratories Limited Process for the synthesis of Losartan potassium
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US20050250827A1 (en) * 2004-05-05 2005-11-10 Etinger Marina Y Preparation of candesartan cilexetil in high purity
KR20120039763A (ko) * 2004-06-08 2012-04-25 버텍스 파마슈티칼스 인코포레이티드 약학 조성물
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AR055395A1 (es) * 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
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EP3219705B1 (en) 2005-12-28 2020-03-11 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of the amorphous form of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
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WO2007109080A2 (en) 2006-03-16 2007-09-27 Vertex Pharmaceuticals Incorporated Deuterated hepatitis c protease inhibitors
WO2008106058A2 (en) * 2007-02-27 2008-09-04 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
HRP20120330T1 (hr) * 2007-02-27 2012-05-31 Vertex Pharmaceuticals Incorporated Sukristali i farmaceutski pripravci koji ih sadrže
NZ583699A (en) * 2007-08-30 2012-04-27 Vertex Pharma Co-crystals of vx-950 (telaprevir) other components and pharmaceutical compositions comprising the same
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
MX2011001782A (es) 2008-08-13 2012-02-08 Vertex Pharma Composicion farmaceutica y su administracion.
MY173823A (en) 2009-01-23 2020-02-24 Hanmi Science Co Ltd Solid pharmaceutical composition comprising amlodipine and losartan and process for producing same
MX2012004792A (es) 2009-10-22 2013-02-01 Vertex Pharma Composiciones para el tratamiento de fibrosis quistica y otras enfermedades cronicas.
EP2560651A1 (en) 2010-04-22 2013-02-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions and administrations thereof
CA2796602A1 (en) 2010-04-22 2011-10-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions and administrations thereof
EP2560649A1 (en) 2010-04-22 2013-02-27 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions and administrations thereof
AU2011255237A1 (en) 2010-05-20 2012-11-29 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions and administrations thereof
CA2809263A1 (en) 2010-08-27 2012-03-01 Eleni Dokou Pharmaceutical composition and administrations thereof
EP2773349A1 (en) 2011-11-02 2014-09-10 Vertex Pharmaceuticals Incorporated Use of (n- [2, 4 -bis (1, 1 -dimethylethyl) - 5 - hydroxyphenyl]- 1, 4 - dihydro - 4 - oxoquinoline - 3 - carboxamide) for treating cftr mediated diseases
JP2015511583A (ja) 2012-02-27 2015-04-20 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated 薬学的組成物およびその投与
AU2013270681A1 (en) 2012-06-08 2014-12-18 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions for the treatment of CFTR -mediated disorders
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RU2744460C2 (ru) 2014-04-15 2021-03-09 Вертекс Фармасьютикалз Инкорпорейтед Фармацевтические композиции для лечения заболеваний, опосредованных муковисцидозным трансмембранным регулятором проводимости
MA41051B1 (fr) 2014-10-06 2020-11-30 Vertex Pharma Modulateurs du régulateur de conductance transmembranaire de la mucoviscidose
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WO2020214921A1 (en) 2019-04-17 2020-10-22 Vertex Pharmaceuticals Incorporated Solid forms of modulators of cftr
UY38696A (es) 2019-05-14 2020-11-30 Vertex Pharma Moduladores de alfa-1 antitripsina
WO2020242935A1 (en) 2019-05-29 2020-12-03 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
WO2021030552A1 (en) 2019-08-14 2021-02-18 Vertex Pharmaceuticals Incorporated Crystalline forms of cftr modulators
TWI899097B (zh) 2019-08-14 2025-10-01 美商維泰克斯製藥公司 製備cftr調節劑之方法
BR112022011516A2 (pt) 2019-12-20 2022-08-23 Principia Biopharma Inc Formas sólidas de 2-[3-[4-amino-3-(2-flúor-4-fenóxi-fenil)pirazol[3,4-d]pirimidin-1-il]piperidina-1-carbonil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enenitrila
WO2021154997A1 (en) 2020-01-29 2021-08-05 Vertex Pharmaceuticals Incorporated Inhibitors of apol1 and methods of using same
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CR20230120A (es) 2020-08-07 2023-09-01 Vertex Pharma Moduladores del regulador de la conductancia transmembrana de la fibrosis quística
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WO2022109553A2 (en) 2020-11-17 2022-05-27 Vertex Pharmaceuticals Incorporated Solid forms of 4-(5-(4-fluorophenyl)-6-tetrahydro-2h-pyran-4-yl)- 1,5-dihydropyrrolo[2,3-f]indazol-7-yl)benzoic acid
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JP2025517323A (ja) 2022-05-16 2025-06-05 バーテックス ファーマシューティカルズ インコーポレイテッド Cftrモジュレーターとしての大環状化合物の固体形態及びその調製
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US20260034064A1 (en) 2022-08-04 2026-02-05 Vertex Pharmaceuticals Incorporated Compositions for the treatment of cftr-mediated diseases
PE20251573A1 (es) 2022-09-09 2025-06-12 Vertex Pharma Moduladores de la alfa-1 antitripsina
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WO2025090511A1 (en) 2023-10-23 2025-05-01 Vertex Pharmaceuticals Incorporated Methods of preparing modulators of sodium channels and solid forms of the same for treating pain
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Also Published As

Publication number Publication date
US7332612B2 (en) 2008-02-19
PL374442A1 (en) 2005-10-17
US20080096945A1 (en) 2008-04-24
JP2009173685A (ja) 2009-08-06
WO2003048135A1 (en) 2003-06-12
AU2002360386A1 (en) 2003-06-17
EP1458693A1 (en) 2004-09-22
ES2234451T1 (es) 2005-07-01
CA2465597A1 (en) 2003-06-12
HUP0501067A2 (en) 2006-02-28
KR20050044450A (ko) 2005-05-12
EP1458693A4 (en) 2005-02-09
CN1612866A (zh) 2005-05-04
IS7262A (is) 2004-05-13
CA2672549A1 (en) 2003-06-12
MXPA04004657A (es) 2004-08-13
NO20042434L (no) 2004-06-11
US20040006237A1 (en) 2004-01-08
HRP20040510A2 (en) 2005-08-31
JP2006504618A (ja) 2006-02-09

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