IL161347A0 - Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage - Google Patents

Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Info

Publication number
IL161347A0
IL161347A0 IL16134702A IL16134702A IL161347A0 IL 161347 A0 IL161347 A0 IL 161347A0 IL 16134702 A IL16134702 A IL 16134702A IL 16134702 A IL16134702 A IL 16134702A IL 161347 A0 IL161347 A0 IL 161347A0
Authority
IL
Israel
Prior art keywords
imidazol
phenyl
substituted
piperidine derivatives
ischaemic damage
Prior art date
Application number
IL16134702A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL161347A0 publication Critical patent/IL161347A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL16134702A 2001-10-15 2002-10-10 Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage IL161347A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203927 2001-10-15
PCT/EP2002/011371 WO2003039440A2 (en) 2001-10-15 2002-10-10 Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Publications (1)

Publication Number Publication Date
IL161347A0 true IL161347A0 (en) 2004-09-27

Family

ID=8181081

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16134702A IL161347A0 (en) 2001-10-15 2002-10-10 Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Country Status (27)

Country Link
US (1) US7390822B2 (es)
EP (1) EP1438049B1 (es)
JP (1) JP4418676B2 (es)
KR (1) KR100967599B1 (es)
CN (1) CN1283252C (es)
AR (1) AR036800A1 (es)
AT (1) ATE345799T1 (es)
AU (1) AU2002363369B2 (es)
BR (1) BR0213325A (es)
CA (1) CA2462374C (es)
CY (1) CY1106335T1 (es)
DE (1) DE60216310T2 (es)
EA (1) EA007657B1 (es)
ES (1) ES2276980T3 (es)
HK (1) HK1072562A1 (es)
HR (1) HRP20040325A2 (es)
HU (1) HUP0402332A3 (es)
IL (1) IL161347A0 (es)
MX (1) MXPA04003480A (es)
MY (1) MY139586A (es)
NO (1) NO20041681L (es)
NZ (1) NZ531733A (es)
PL (1) PL370371A1 (es)
PT (1) PT1438049E (es)
UA (1) UA75980C2 (es)
WO (1) WO2003039440A2 (es)
ZA (1) ZA200402816B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200403058A (en) * 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
AR044010A1 (es) * 2003-04-11 2005-08-24 Janssen Pharmaceutica Nv Uso de derivados de 4-fenil-4- [1h-imidazol-2-il]- piperidina sustituidos como agonistas delta opioideos no peptidos selectivos, con actividad antidepresiva y ansiolitica
WO2005005478A2 (en) * 2003-07-02 2005-01-20 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor; delta 1 (oprd1)
WO2005015242A1 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
TW200633990A (en) * 2004-11-18 2006-10-01 Takeda Pharmaceuticals Co Amide compound
CA2706991A1 (en) * 2007-11-30 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Heteroaryl-substituted piperidines
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009056387B9 (de) * 2009-10-30 2020-05-07 Osram Opto Semiconductors Gmbh Kantenemittierender Halbleiterlaser mit einem Phasenstrukturbereich zur Selektion lateraler Lasermoden
EP3697410A4 (en) 2017-10-19 2021-08-11 Amgen Inc. BENZIMIDAZOLE DERIVATIVES AND THEIR USES
CN113209294B (zh) * 2020-02-05 2023-06-13 复旦大学 Dor激动剂在制备对抗肾脏纤维化药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL185124B1 (pl) 1995-03-06 2003-02-28 Interneuron Pharmaceuticals Zastosowanie cytykoliny oraz jej kompozycja do wytwarzania leku przeznaczonego do ochrony tkanki mózgowej
ES2251740T3 (es) 1996-08-23 2006-05-01 Ludwig Institute For Cancer Research Factor de crecimiento de celulas de endotelio vascular d recombinante (vegf-d).
CA2287538A1 (en) 1997-04-25 1998-11-05 Collateral Therapeutics Truncated vegf-related proteins
US6103722A (en) * 1997-07-23 2000-08-15 The Medical College Of Wisconsin Research Foundation Inc. Ischemic preconditioning
GB2332373A (en) * 1997-12-19 1999-06-23 Merck & Co Inc Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter
JP4601175B2 (ja) 1998-12-19 2010-12-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗ヒスタミン性スピロ化合物
EP1038872A1 (en) * 1999-02-22 2000-09-27 Pfizer Products Inc. 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands
US6297256B1 (en) * 1999-06-15 2001-10-02 Neurogen Corporation Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands
UA76224C2 (en) * 2001-10-15 2006-07-17 Janssen Pharmaceutica Nv Substituted 4-phenyl 4-[1h-imidazol-2-yl]-piperidine derivatives and use thereof as selective non-peptide delta-opioid agonists
FR2831166B1 (fr) 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
UA75980C2 (en) 2006-06-15
AU2002363369B2 (en) 2008-08-21
WO2003039440A2 (en) 2003-05-15
HUP0402332A3 (en) 2009-07-28
KR20050035120A (ko) 2005-04-15
ZA200402816B (en) 2005-06-29
US20050004170A1 (en) 2005-01-06
AR036800A1 (es) 2004-10-06
JP4418676B2 (ja) 2010-02-17
PL370371A1 (en) 2005-05-16
CA2462374A1 (en) 2003-05-15
EP1438049B1 (en) 2006-11-22
EA200400547A1 (ru) 2004-10-28
ATE345799T1 (de) 2006-12-15
CY1106335T1 (el) 2011-10-12
CA2462374C (en) 2011-01-18
HUP0402332A2 (hu) 2005-02-28
HRP20040325A2 (en) 2005-04-30
CN1568186A (zh) 2005-01-19
BR0213325A (pt) 2004-10-13
MY139586A (en) 2009-10-30
MXPA04003480A (es) 2004-07-30
DE60216310D1 (de) 2007-01-04
KR100967599B1 (ko) 2010-07-05
ES2276980T3 (es) 2007-07-01
EA007657B1 (ru) 2006-12-29
WO2003039440A3 (en) 2003-12-18
HK1072562A1 (en) 2005-09-02
NO20041681L (no) 2004-04-23
US7390822B2 (en) 2008-06-24
EP1438049A2 (en) 2004-07-21
JP2005507943A (ja) 2005-03-24
CN1283252C (zh) 2006-11-08
PT1438049E (pt) 2007-02-28
NZ531733A (en) 2006-04-28
DE60216310T2 (de) 2007-06-21

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