HK1072562A1 - Substituted 4-phenyl-4-(1H-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage - Google Patents

Substituted 4-phenyl-4-(1H-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Info

Publication number
HK1072562A1
HK1072562A1 HK05105375A HK05105375A HK1072562A1 HK 1072562 A1 HK1072562 A1 HK 1072562A1 HK 05105375 A HK05105375 A HK 05105375A HK 05105375 A HK05105375 A HK 05105375A HK 1072562 A1 HK1072562 A1 HK 1072562A1
Authority
HK
Hong Kong
Prior art keywords
imidazol
phenyl
substituted
piperidine derivatives
ischaemic damage
Prior art date
Application number
HK05105375A
Other languages
English (en)
Inventor
Frans Eduard Janssens
Joseph Elisabeth Leenaerts
Francisco Javi Fernandez-Gadea
Antonio Gomez-Sanchez
Willem Flameng
Paul Johannes Ludovi Herijgers
Theo Frans Meert
Marcel J Borgers
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1072562A1 publication Critical patent/HK1072562A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK05105375A 2001-10-15 2005-06-28 Substituted 4-phenyl-4-(1H-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage HK1072562A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203927 2001-10-15
PCT/EP2002/011371 WO2003039440A2 (en) 2001-10-15 2002-10-10 Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Publications (1)

Publication Number Publication Date
HK1072562A1 true HK1072562A1 (en) 2005-09-02

Family

ID=8181081

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05105375A HK1072562A1 (en) 2001-10-15 2005-06-28 Substituted 4-phenyl-4-(1H-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage

Country Status (27)

Country Link
US (1) US7390822B2 (es)
EP (1) EP1438049B1 (es)
JP (1) JP4418676B2 (es)
KR (1) KR100967599B1 (es)
CN (1) CN1283252C (es)
AR (1) AR036800A1 (es)
AT (1) ATE345799T1 (es)
AU (1) AU2002363369B2 (es)
BR (1) BR0213325A (es)
CA (1) CA2462374C (es)
CY (1) CY1106335T1 (es)
DE (1) DE60216310T2 (es)
EA (1) EA007657B1 (es)
ES (1) ES2276980T3 (es)
HK (1) HK1072562A1 (es)
HR (1) HRP20040325A2 (es)
HU (1) HUP0402332A3 (es)
IL (1) IL161347A0 (es)
MX (1) MXPA04003480A (es)
MY (1) MY139586A (es)
NO (1) NO20041681L (es)
NZ (1) NZ531733A (es)
PL (1) PL370371A1 (es)
PT (1) PT1438049E (es)
UA (1) UA75980C2 (es)
WO (1) WO2003039440A2 (es)
ZA (1) ZA200402816B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200403058A (en) * 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
CL2004000754A1 (es) * 2003-04-11 2005-02-25 Janssen Pharmaceutica Nv Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central.
WO2005005478A2 (en) * 2003-07-02 2005-01-20 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor; delta 1 (oprd1)
WO2005015242A1 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
TW200633990A (en) * 2004-11-18 2006-10-01 Takeda Pharmaceuticals Co Amide compound
EP2227466B1 (de) 2007-11-30 2011-04-20 Bayer Schering Pharma Aktiengesellschaft Heteroaryl-substituierte piperidine
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009056387B9 (de) * 2009-10-30 2020-05-07 Osram Opto Semiconductors Gmbh Kantenemittierender Halbleiterlaser mit einem Phasenstrukturbereich zur Selektion lateraler Lasermoden
CA3079081A1 (en) 2017-10-19 2019-04-25 Michael D. Bartberger Benzimidazole derivatives and their uses
CN113209294B (zh) * 2020-02-05 2023-06-13 复旦大学 Dor激动剂在制备对抗肾脏纤维化药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2244968T3 (es) 1995-03-06 2005-12-16 Interneuron Pharmaceuticals Incorporated Reduccion del volumen de infarto usando citocolina.
EP0956339B1 (en) 1996-08-23 2005-10-12 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor d (vegf-d)
NZ514872A (en) 1997-04-25 2005-01-28 Collateral Therapeutics Truncated VEGF-B, VRF-2, VEGF-C, PlGF, VEGF-3, poxvirus ORF-1 and poxvirus ORF-2 proteins
US6103722A (en) * 1997-07-23 2000-08-15 The Medical College Of Wisconsin Research Foundation Inc. Ischemic preconditioning
GB2332373A (en) 1997-12-19 1999-06-23 Merck & Co Inc Treatment of coronary and/or peripheral ischemia using an antithrombotic agent and an angiogenesis promoter
CA2355939C (en) 1998-12-19 2010-12-14 Janssen Pharmaceutica N.V. Antihistaminic spiro compounds
EP1038872A1 (en) * 1999-02-22 2000-09-27 Pfizer Products Inc. 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands
US6297256B1 (en) * 1999-06-15 2001-10-02 Neurogen Corporation Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands
UA76224C2 (en) * 2001-10-15 2006-07-17 Janssen Pharmaceutica Nv Substituted 4-phenyl 4-[1h-imidazol-2-yl]-piperidine derivatives and use thereof as selective non-peptide delta-opioid agonists
FR2831166B1 (fr) 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
MY139586A (en) 2009-10-30
KR20050035120A (ko) 2005-04-15
IL161347A0 (en) 2004-09-27
ES2276980T3 (es) 2007-07-01
US7390822B2 (en) 2008-06-24
WO2003039440A3 (en) 2003-12-18
PT1438049E (pt) 2007-02-28
EA200400547A1 (ru) 2004-10-28
CN1568186A (zh) 2005-01-19
EP1438049B1 (en) 2006-11-22
BR0213325A (pt) 2004-10-13
UA75980C2 (en) 2006-06-15
WO2003039440A2 (en) 2003-05-15
ZA200402816B (en) 2005-06-29
CA2462374A1 (en) 2003-05-15
JP4418676B2 (ja) 2010-02-17
EP1438049A2 (en) 2004-07-21
CN1283252C (zh) 2006-11-08
AR036800A1 (es) 2004-10-06
HUP0402332A3 (en) 2009-07-28
EA007657B1 (ru) 2006-12-29
DE60216310D1 (de) 2007-01-04
HUP0402332A2 (hu) 2005-02-28
CA2462374C (en) 2011-01-18
JP2005507943A (ja) 2005-03-24
NO20041681L (no) 2004-04-23
MXPA04003480A (es) 2004-07-30
AU2002363369B2 (en) 2008-08-21
PL370371A1 (en) 2005-05-16
ATE345799T1 (de) 2006-12-15
US20050004170A1 (en) 2005-01-06
DE60216310T2 (de) 2007-06-21
NZ531733A (en) 2006-04-28
CY1106335T1 (el) 2011-10-12
KR100967599B1 (ko) 2010-07-05
HRP20040325A2 (en) 2005-04-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181010