IL158929A0 - Oxazol/thiazol derivatives as activators of the hppar-alpha receptor - Google Patents
Oxazol/thiazol derivatives as activators of the hppar-alpha receptorInfo
- Publication number
- IL158929A0 IL158929A0 IL15892902A IL15892902A IL158929A0 IL 158929 A0 IL158929 A0 IL 158929A0 IL 15892902 A IL15892902 A IL 15892902A IL 15892902 A IL15892902 A IL 15892902A IL 158929 A0 IL158929 A0 IL 158929A0
- Authority
- IL
- Israel
- Prior art keywords
- hppar
- oxazol
- activators
- alpha receptor
- thiazol derivatives
- Prior art date
Links
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical class C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 title 1
- 239000012190 activator Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113231.5A GB0113231D0 (en) | 2001-05-31 | 2001-05-31 | Chemical compounds |
| PCT/EP2002/005886 WO2002096895A1 (en) | 2001-05-31 | 2002-05-29 | Oxazol/ thiazol-derivatives activators of the hppar-alpha receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158929A0 true IL158929A0 (en) | 2004-05-12 |
Family
ID=9915636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15892902A IL158929A0 (en) | 2001-05-31 | 2002-05-29 | Oxazol/thiazol derivatives as activators of the hppar-alpha receptor |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7157479B2 (https=) |
| EP (1) | EP1399430B1 (https=) |
| JP (1) | JP2004532267A (https=) |
| KR (1) | KR100859591B1 (https=) |
| CN (1) | CN1307166C (https=) |
| AR (1) | AR034051A1 (https=) |
| AU (1) | AU2002317765B2 (https=) |
| BR (1) | BR0209785A (https=) |
| CA (1) | CA2448205A1 (https=) |
| CO (1) | CO5540297A2 (https=) |
| CY (1) | CY1107206T1 (https=) |
| CZ (1) | CZ20033252A3 (https=) |
| DE (1) | DE60223805T2 (https=) |
| DK (1) | DK1399430T3 (https=) |
| ES (1) | ES2296965T3 (https=) |
| GB (1) | GB0113231D0 (https=) |
| HU (1) | HUP0400043A3 (https=) |
| IL (1) | IL158929A0 (https=) |
| MX (1) | MXPA03011032A (https=) |
| MY (1) | MY132656A (https=) |
| NO (1) | NO20035209L (https=) |
| NZ (1) | NZ529754A (https=) |
| PL (1) | PL367248A1 (https=) |
| PT (1) | PT1399430E (https=) |
| SI (1) | SI1399430T1 (https=) |
| TW (1) | TWI245760B (https=) |
| WO (1) | WO2002096895A1 (https=) |
| ZA (1) | ZA200309095B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04003398A (es) * | 2001-10-12 | 2004-11-22 | Nippon Chemiphar Co | Activador para el receptor o activado con el proliferador de peroxisoma. |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| GB0323702D0 (en) * | 2003-10-09 | 2003-11-12 | Smithkline Beecham Corp | Chemical compound |
| CN1875002B (zh) | 2003-11-05 | 2011-08-03 | 霍夫曼-拉罗奇有限公司 | 作为ppar激动剂的苯基衍生物 |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
| CN101007790B (zh) * | 2006-01-27 | 2011-03-30 | 北京摩力克科技有限公司 | 草氨酸衍生物、其制备方法和医药用途 |
| FR2901792A1 (fr) * | 2006-06-06 | 2007-12-07 | Negma Lerads Soc Par Actions S | DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE |
| CA2744985C (en) * | 2008-12-01 | 2014-05-06 | Mitsubishi Tanabe Pharma Corporation | Carboxylic acid derivative containing thiazole ring useful for the prevention or treatment of hyperlipidemia |
| CN110803996B (zh) * | 2019-11-13 | 2022-01-11 | 台州市创源工业技术有限公司 | 一种羟基苄胺的合成方法 |
| CN116511225B (zh) * | 2023-03-30 | 2025-09-23 | 江南大学 | 一种油酸基des液体及其制备方法和它在厌氧发酵液高效浓缩中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204277B1 (en) * | 1996-08-19 | 2001-03-20 | Japan Tobacco Inc. | Propionic acid derivatives and applications thereof |
| ATE451346T1 (de) | 1998-03-10 | 2009-12-15 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| EP1177176B1 (en) * | 1999-04-28 | 2006-04-19 | Aventis Pharma Deutschland GmbH | Tri-aryl acid derivatives as ppar receptor ligands |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
| DE60005973T2 (de) * | 1999-08-27 | 2004-05-13 | Eli Lilly And Co., Indianapolis | Biaryl-oxa(thia)zolderivate und ihre verwendung als ppars modulatoren |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| GB0113233D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
-
2001
- 2001-05-31 GB GBGB0113231.5A patent/GB0113231D0/en not_active Ceased
-
2002
- 2002-05-29 DE DE60223805T patent/DE60223805T2/de not_active Expired - Fee Related
- 2002-05-29 US US10/478,936 patent/US7157479B2/en not_active Expired - Fee Related
- 2002-05-29 AU AU2002317765A patent/AU2002317765B2/en not_active Ceased
- 2002-05-29 KR KR1020037015678A patent/KR100859591B1/ko not_active Expired - Fee Related
- 2002-05-29 PL PL02367248A patent/PL367248A1/xx not_active Application Discontinuation
- 2002-05-29 ES ES02747331T patent/ES2296965T3/es not_active Expired - Lifetime
- 2002-05-29 IL IL15892902A patent/IL158929A0/xx unknown
- 2002-05-29 EP EP02747331A patent/EP1399430B1/en not_active Expired - Lifetime
- 2002-05-29 BR BR0209785-0A patent/BR0209785A/pt not_active IP Right Cessation
- 2002-05-29 AR ARP020101999A patent/AR034051A1/es unknown
- 2002-05-29 SI SI200230654T patent/SI1399430T1/sl unknown
- 2002-05-29 PT PT02747331T patent/PT1399430E/pt unknown
- 2002-05-29 CN CNB028149424A patent/CN1307166C/zh not_active Expired - Fee Related
- 2002-05-29 NZ NZ529754A patent/NZ529754A/en unknown
- 2002-05-29 WO PCT/EP2002/005886 patent/WO2002096895A1/en not_active Ceased
- 2002-05-29 CZ CZ20033252A patent/CZ20033252A3/cs unknown
- 2002-05-29 JP JP2003500074A patent/JP2004532267A/ja active Pending
- 2002-05-29 MY MYPI20021973A patent/MY132656A/en unknown
- 2002-05-29 MX MXPA03011032A patent/MXPA03011032A/es active IP Right Grant
- 2002-05-29 CA CA002448205A patent/CA2448205A1/en not_active Abandoned
- 2002-05-29 HU HU0400043A patent/HUP0400043A3/hu unknown
- 2002-05-29 DK DK02747331T patent/DK1399430T3/da active
- 2002-05-29 TW TW091111392A patent/TWI245760B/zh not_active IP Right Cessation
-
2003
- 2003-11-21 ZA ZA200309095A patent/ZA200309095B/en unknown
- 2003-11-24 NO NO20035209A patent/NO20035209L/no not_active Application Discontinuation
- 2003-12-03 CO CO03106490A patent/CO5540297A2/es not_active Application Discontinuation
-
2008
- 2008-02-19 CY CY20081100202T patent/CY1107206T1/el unknown
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