IL158462A0 - An assay for detecting inhibitors of the enzyme myeloperoxidase - Google Patents

An assay for detecting inhibitors of the enzyme myeloperoxidase

Info

Publication number
IL158462A0
IL158462A0 IL15846202A IL15846202A IL158462A0 IL 158462 A0 IL158462 A0 IL 158462A0 IL 15846202 A IL15846202 A IL 15846202A IL 15846202 A IL15846202 A IL 15846202A IL 158462 A0 IL158462 A0 IL 158462A0
Authority
IL
Israel
Prior art keywords
myeloperoxidase
detector molecule
reacting
oxidised
assay
Prior art date
Application number
IL15846202A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/SE2001/001014 external-priority patent/WO2001085146A1/en
Priority claimed from SE0103766A external-priority patent/SE0103766D0/xx
Priority claimed from PCT/US2002/000877 external-priority patent/WO2002068610A2/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL158462A0 publication Critical patent/IL158462A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL15846202A 2001-05-08 2002-05-06 An assay for detecting inhibitors of the enzyme myeloperoxidase IL158462A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/SE2001/001014 WO2001085146A1 (en) 2000-05-12 2001-05-08 Pharmaceutical compounds for treating copd
SE0103766A SE0103766D0 (sv) 2001-11-09 2001-11-09 Novel assay
PCT/US2002/000877 WO2002068610A2 (en) 2001-01-12 2002-01-11 Compositions and methods for affecting virulence determinants in bacteria

Publications (1)

Publication Number Publication Date
IL158462A0 true IL158462A0 (en) 2004-05-12

Family

ID=26655416

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15846202A IL158462A0 (en) 2001-05-08 2002-05-06 An assay for detecting inhibitors of the enzyme myeloperoxidase

Country Status (12)

Country Link
EP (1) EP1387893B1 (ja)
JP (1) JP4095446B2 (ja)
CN (1) CN1228452C (ja)
AT (1) ATE346951T1 (ja)
AU (1) AU2002258327B2 (ja)
CA (1) CA2446039A1 (ja)
DE (1) DE60216442T2 (ja)
DK (1) DK1387893T3 (ja)
ES (1) ES2275865T3 (ja)
IL (1) IL158462A0 (ja)
NZ (1) NZ528999A (ja)
WO (1) WO2002090575A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039385A1 (es) 2002-04-19 2005-02-16 Astrazeneca Ab Derivados de tioxantina como inhibidores de la mieloperoxidasa
US7195891B2 (en) 2004-08-11 2007-03-27 General Atomics Methods and compositions of enzymatic cycling based assays for myeloperoxidase
MY140748A (en) 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en) 2006-06-05 2008-01-16 Astrazeneca Ab New compounds
EA027324B1 (ru) 2011-11-11 2017-07-31 Пфайзер Инк. 2-тиопиримидиноны
PE20180503A1 (es) 2015-05-05 2018-03-09 Pfizer 2-tiopirimidinonas
CN105891182B (zh) * 2016-06-17 2018-05-29 云南圣清环境监测科技有限公司 一种对过氧化氢酶定量的方法
CN106908601B (zh) * 2017-03-06 2019-02-12 海格德生物科技（深圳）有限公司 人髓过氧化物酶活性及总量检测试剂盒及检测方法和制备方法
CN109975282A (zh) * 2019-04-04 2019-07-05 华侨大学 一种基于酶催化碘化钾氧化显色检测过氧化氢含量的分光光度法
CN114509429A (zh) * 2021-12-20 2022-05-17 苏州百源基因技术有限公司 一种尿碘检测试剂盒及其使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976823A (en) * 1997-03-19 1999-11-02 Integrated Biomedical Technology, Inc. Low range total available chlorine test strip

Also Published As

Publication number Publication date
JP4095446B2 (ja) 2008-06-04
JP2004525646A (ja) 2004-08-26
DE60216442T2 (de) 2007-09-27
CN1228452C (zh) 2005-11-23
CN1507495A (zh) 2004-06-23
CA2446039A1 (en) 2002-11-14
AU2002258327B2 (en) 2007-03-01
DE60216442D1 (de) 2007-01-11
EP1387893A1 (en) 2004-02-11
WO2002090575A1 (en) 2002-11-14
DK1387893T3 (da) 2007-02-19
EP1387893B1 (en) 2006-11-29
ATE346951T1 (de) 2006-12-15
ES2275865T3 (es) 2007-06-16
NZ528999A (en) 2005-04-29

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