GB2452208A - Electrochemical detection of amine compounds - Google Patents

Electrochemical detection of amine compounds Download PDF

Info

Publication number
GB2452208A
GB2452208A GB0823048A GB0823048A GB2452208A GB 2452208 A GB2452208 A GB 2452208A GB 0823048 A GB0823048 A GB 0823048A GB 0823048 A GB0823048 A GB 0823048A GB 2452208 A GB2452208 A GB 2452208A
Authority
GB
United Kingdom
Prior art keywords
compound
amine compounds
electrochemical detection
reaction
working electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0823048A
Other versions
GB0823048D0 (en
GB2452208B (en
Inventor
Richard Guy Compton
Craig E Banks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of GB0823048D0 publication Critical patent/GB0823048D0/en
Publication of GB2452208A publication Critical patent/GB2452208A/en
Application granted granted Critical
Publication of GB2452208B publication Critical patent/GB2452208B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/302—Electrodes, e.g. test electrodes; Half-cells pH sensitive, e.g. quinhydron, antimony or hydrogen electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48714—Physical analysis of biological material of liquid biological material by electrical means for determining substances foreign to the organism, e.g. drugs or heavy metals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines

Abstract

Method of detecting an amine compound in a sample, which comprises contacting the sample with a second compound in the presence of a working electrode and an electrolyte, wherein said second compound is capable of undergoing a reaction with the amine compound, and wherein the second compound and/or a product of that reaction is capable of undergoing a redox reaction at the working electrode having a detectable redox couple; and determining the electrochemical response of the working electrode thereto. Electrochemical sensors and electrode materials for use in said method are also provided.

Description

GB 2452208 A continuation (56) cont Moliner-Martinez V. et al., "Detector supports: application to aliphatic amines in wastewater", Talanta, vol.65, no. 1, 15 January 2005, pp217-222, XP004638027 Goodwin A. et al., "Tagging of model amphetamines with sodium 1,2-naphthoquinone-4-sulfonate: Application to the indirect electrochemical detection of amphetamines ir oral (saliva) fluid", Electroanalysis, vol. 18, no. 18, 18 September 2006, pp1833-1 837, XP002453485
(58) Field of Search by ISA:
INT CL GO1N Other: EPO-Internal, COMPENDEX, BIOSIS
GB0823048A 2006-07-03 2007-07-03 Electrochemical detection of amine compounds Expired - Fee Related GB2452208B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0613182A GB0613182D0 (en) 2006-07-03 2006-07-03 Method of detection
PCT/GB2007/050373 WO2008003999A1 (en) 2006-07-03 2007-07-03 Electrochemical detection of amine compounds

Publications (3)

Publication Number Publication Date
GB0823048D0 GB0823048D0 (en) 2009-01-28
GB2452208A true GB2452208A (en) 2009-02-25
GB2452208B GB2452208B (en) 2011-06-08

Family

ID=36888535

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0613182A Ceased GB0613182D0 (en) 2006-07-03 2006-07-03 Method of detection
GB0823048A Expired - Fee Related GB2452208B (en) 2006-07-03 2007-07-03 Electrochemical detection of amine compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0613182A Ceased GB0613182D0 (en) 2006-07-03 2006-07-03 Method of detection

Country Status (2)

Country Link
GB (2) GB0613182D0 (en)
WO (1) WO2008003999A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0807534D0 (en) 2008-04-24 2008-06-04 Oxtox Ltd Assay
GB0902493D0 (en) 2009-02-13 2009-04-01 Oxtox Ltd Assay method
ES2519891B2 (en) * 2013-05-07 2015-03-05 Uni De València Passive device for the detection and / or determination in situ of amines in gases
CN110045053A (en) * 2019-04-30 2019-07-23 华南理工大学 A kind of QuEChERS pre-treating method of the analysis of the amphetamines suitable for blood

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0794429A1 (en) * 1996-03-07 1997-09-10 Matsushita Electric Industrial Co., Ltd. Cholesterol sensor
WO2005085825A1 (en) * 2004-03-04 2005-09-15 Isis Innovation Ltd Electrochemical sensors
WO2006009328A1 (en) * 2004-07-23 2006-01-26 Canon Kabushiki Kaisha Enzyme electrode, sensor, fuel cell, and electrochemical reactor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0794429A1 (en) * 1996-03-07 1997-09-10 Matsushita Electric Industrial Co., Ltd. Cholesterol sensor
WO2005085825A1 (en) * 2004-03-04 2005-09-15 Isis Innovation Ltd Electrochemical sensors
WO2006009328A1 (en) * 2004-07-23 2006-01-26 Canon Kabushiki Kaisha Enzyme electrode, sensor, fuel cell, and electrochemical reactor

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Everett W. R. et al, "Mediated bioeletrocatalytic determination of organophosphorous pesticides with a tyrosinase-based oxygen biosensor", Analytical Chemistry, 15 February 1998, vol. 70, no. 4, pp807-810, XP002453484 *
Falco P. C. et al., "Improved amphetamine and methamphetamine determination in urine by normal-phase high-performance liquid chromatogrphy with sodium 1, 2-naphthoquinone 4-sulphonate as derivatizing agent", Journal of Chromatography B, vol. 663, no. 2, 29 January 1995, pp235-245, XP004043681 *
Goodwin A. et al., "Tagging of model amphetamines with sodium 1,2-naphthoquinone-4-sulfonate: Application to the indirect electrochemical detection of amphetamines ir oral (saliva) fluid", Electroanalysis, vol. 18, no. 18, 18 September 2006, pp1833-1837, XP002453485 *
Kramer T. et al., "Determination of amphetamine, methamphetamine and amphetamine-derived designer drugs or medicaments in blood and urine", Journal of Chromatography B, vol. 713, no. 1, 21 August 1998, pp163-187, XP004127091 *
Mazeikiene R. et al., "Doping of polyaniline by some redox active organic anions", European Polymer Journal, vol. 36, no. 7, July 2000, pp1347-1353, XP004193814 *
Moliner-Martinez Y. et al., "Detector supports: application to aliphatic amines in wastewater", Talanta, vol. 65, no. 1, 15 January 2005, pp217-222, XP004638027 *

Also Published As

Publication number Publication date
WO2008003999A1 (en) 2008-01-10
GB0823048D0 (en) 2009-01-28
GB2452208B (en) 2011-06-08
GB0613182D0 (en) 2006-08-09

Similar Documents

Publication Publication Date Title
ATE532063T1 (en) ELECTROCHEMICAL BIOSENSOR
HK1135435A1 (en) A reagent formulation using ruthenium hexamine as a mediator for electrochemical test strips
HK1062032A1 (en) Mediator stabilized reagent compositions and methods for their use in electrochemical analyte detection assays
AU2003239672A1 (en) Analyte measurement
EP1671118A4 (en) Cyanide sensing compounds and uses thereof
WO2003085372A8 (en) Biosensor membranes composed of polymers containing heterocyclic nitrogens
Zhang et al. Amperometric sensor based on ferrocene-doped silica nanoparticles as an electron transfer mediator for the determination of glucose in rat brain coupled to in vivo microdialysis
ATE520661T1 (en) HETEROCYCLIC COMPOUNDS WITH QUATERNARY NITROGEN FOR THE DETECTION OF AQUEOUS MONOSACHARIDES IN PHYSIOLOGICAL LIQUIDS
MX347099B (en) Transient decay amperometry.
WO2009013884A1 (en) Reagent for measurement of concentration of lead, and method for measurement of concentration of lead
GB2452208A (en) Electrochemical detection of amine compounds
DK1557473T3 (en) Reagent composition to distinguish beta-lactamases, kits and methods thereof
Al-Majed et al. The voltammetric study and determination of ramipril in dosage forms and biological fluids
CN104165909A (en) Biological electrochemical detection method of fumaric acid
RU2011110197A (en) DEVICE AND METHOD FOR MEASURING MOLECULE CONCENTRATIONS THROUGH A BARRIER
CA2617914A1 (en) Method for distinguishing electrochemical sensors
NO20071564L (en) Process for determining the concentration of analytes in samples by direct transfer of enzymes
MXPA03010143A (en) An assay for detecting inhibitors of the enzyme mueloperokidase.
Stefan et al. On-line simultaneous determination of S-and R-perindopril using amperometric biosensors as detectors in flow systems
Chen et al. Potentiometric determination of trypsin using a polymeric membrane polycation-sensitive electrode based on current-controlled reagent delivery
Yu et al. A [32P] NAD+-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors
DE60216442D1 (en) TEST FOR THE DETECTION OF INHIBITORS OF ENZYME MYELOPEROKIDASE
do Nascimento et al. Determination of cadmium, lead and thallium in highly saline hemodialysis solutions by potentiometric stripping analysis (PSA)
Liang et al. Spectrofluorimetric determination of cysteine by 5-maleimidyl-2-(m-methylphenyl) benzoxazole
WO2008096757A1 (en) Method for detection of biological molecule and chip for detection of biological molecule

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20150703