IL158332A0 - Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors - Google Patents
Furan and thiophene derivatives that activate human peroxisome proliferator activated receptorsInfo
- Publication number
- IL158332A0 IL158332A0 IL15833202A IL15833202A IL158332A0 IL 158332 A0 IL158332 A0 IL 158332A0 IL 15833202 A IL15833202 A IL 15833202A IL 15833202 A IL15833202 A IL 15833202A IL 158332 A0 IL158332 A0 IL 158332A0
- Authority
- IL
- Israel
- Prior art keywords
- furan
- peroxisome proliferator
- activated receptors
- proliferator activated
- thiophene derivatives
- Prior art date
Links
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 title 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title 1
- 150000003577 thiophenes Chemical class 0.000 title 1
- 101000741788 Homo sapiens Peroxisome proliferator-activated receptor alpha Proteins 0.000 abstract 1
- 102100038831 Peroxisome proliferator-activated receptor alpha Human genes 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0111523.7A GB0111523D0 (en) | 2001-05-11 | 2001-05-11 | Chemical compounds |
| PCT/GB2002/002152 WO2002092590A1 (en) | 2001-05-11 | 2002-05-09 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158332A0 true IL158332A0 (en) | 2004-05-12 |
Family
ID=9914442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15833202A IL158332A0 (en) | 2001-05-11 | 2002-05-09 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7091237B2 (enExample) |
| EP (1) | EP1392674B1 (enExample) |
| JP (1) | JP2004534035A (enExample) |
| KR (1) | KR20040023600A (enExample) |
| CN (1) | CN1507442A (enExample) |
| AT (1) | ATE301649T1 (enExample) |
| BR (1) | BR0209468A (enExample) |
| CA (1) | CA2446797A1 (enExample) |
| CO (1) | CO5540343A2 (enExample) |
| CZ (1) | CZ20033064A3 (enExample) |
| DE (1) | DE60205481T2 (enExample) |
| ES (1) | ES2247322T3 (enExample) |
| GB (1) | GB0111523D0 (enExample) |
| HU (1) | HUP0304051A3 (enExample) |
| IL (1) | IL158332A0 (enExample) |
| MX (1) | MXPA03010285A (enExample) |
| NO (1) | NO20034986L (enExample) |
| PL (1) | PL367478A1 (enExample) |
| WO (1) | WO2002092590A1 (enExample) |
| ZA (1) | ZA200308352B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041691B1 (en) | 1999-06-30 | 2006-05-09 | Amgen Inc. | Compounds for the modulation of PPARγ activity |
| US20030171399A1 (en) | 2000-06-28 | 2003-09-11 | Tularik Inc. | Quinolinyl and benzothiazolyl modulators |
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| GB0113232D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical process |
| MXPA04001258A (es) | 2001-08-10 | 2005-06-06 | Nippon Chemiphar Co | Activador para el receptor d que responde al proliferador de peroxisoma. |
| ITRM20020014A1 (it) * | 2002-01-15 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del |
| US6833380B2 (en) | 2002-03-07 | 2004-12-21 | Warner-Lambert Company, Llc | Compounds that modulate PPAR activity and methods of preparation |
| US20030207924A1 (en) * | 2002-03-07 | 2003-11-06 | Xue-Min Cheng | Compounds that modulate PPAR activity and methods of preparation |
| US6875780B2 (en) * | 2002-04-05 | 2005-04-05 | Warner-Lambert Company | Compounds that modulate PPAR activity and methods for their preparation |
| US7553867B2 (en) | 2002-09-06 | 2009-06-30 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| JP2005035966A (ja) * | 2002-09-06 | 2005-02-10 | Takeda Chem Ind Ltd | フランまたはチオフェン誘導体およびその医薬用途 |
| US7960369B2 (en) * | 2002-11-08 | 2011-06-14 | Takeda Pharmaceutical Company Limited | Receptor function regulator |
| AU2003296402A1 (en) * | 2003-01-06 | 2004-08-10 | Eli Lilly And Company | Thiophene derivative ppar modulators |
| US7244763B2 (en) | 2003-04-17 | 2007-07-17 | Warner Lambert Company Llc | Compounds that modulate PPAR activity and methods of preparation |
| EP1493739A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| US7223761B2 (en) | 2003-10-03 | 2007-05-29 | Amgen Inc. | Salts and polymorphs of a potent antidiabetic compound |
| KR20080042188A (ko) | 2003-11-05 | 2008-05-14 | 에프. 호프만-라 로슈 아게 | Ｐｐａｒ 작용제로서 페닐 유도체 |
| WO2005063729A1 (en) | 2003-12-25 | 2005-07-14 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl)propanoic acid derivatives |
| EP1698624B1 (en) | 2003-12-26 | 2012-06-27 | Takeda Pharmaceutical Company Limited | Phenylpropanoic acid derivatives |
| GB0403148D0 (en) * | 2004-02-12 | 2004-03-17 | Smithkline Beecham Corp | Chemical compounds |
| DE602004004631D1 (de) | 2004-04-01 | 2007-03-22 | Sanofi Aventis Deutschland | Oxadiazolone, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Pharmazeutika |
| EP1854784A1 (en) * | 2005-02-28 | 2007-11-14 | Nippon Chemiphar Co., Ltd. | Activator for peroxisome proliferator activating receptor |
| WO2006121223A1 (en) * | 2005-05-07 | 2006-11-16 | Heon Joong Kang | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same |
| KR20080014075A (ko) * | 2005-05-25 | 2008-02-13 | 닛뽕 케미파 가부시키가이샤 | 페록시좀 증식제 활성화 수용체의 활성화제 |
| EP1931337B1 (en) | 2005-09-29 | 2013-10-23 | Sanofi | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
| AU2006299092A1 (en) | 2005-09-29 | 2007-04-12 | Sanofi-Aventis | Phenyl-(1,2,4)-oxadiazol-5-one derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals |
| WO2007127502A2 (en) * | 2006-01-10 | 2007-11-08 | Smithkline Beecham Corporation | Polymorphic form of { 2-methyl-4- [ 4-methyl-2- ( 4-triflu0r0methylphenyl) thiazol -5- ylmethylthiol phenoxy }-acetic acid |
| RU2435764C2 (ru) | 2006-04-18 | 2011-12-10 | Ниппон Кемифар Ко., Лтд. | АГЕНТ, АКТИВИРУЮЩИЙ РЕЦЕПТОР, АКТИВИРУЕМЫЙ ПРОЛИФЕРАТОРАМИ ПЕРОКСИСОМ δ |
| KR101467590B1 (ko) * | 2006-08-22 | 2014-12-01 | 랜박시 래보러터리스 리미티드 | 매트릭스 메탈로프로테나제 저해제 |
| FR2910894A1 (fr) * | 2006-12-29 | 2008-07-04 | Genfit Sa | Derives de 3-phenyl-1-(phenylthienyl)propan-1-one et de 3-phenyl-1-(phenylfuranyl)propan-1-one substitues, preparation et utilisation. |
| CA2672420A1 (en) | 2006-12-29 | 2008-07-10 | The Salk Institute For Biological Studies | Methods for enhancing exercise performance |
| EA200970793A1 (ru) * | 2007-02-23 | 2010-02-26 | Эли Лилли Энд Компани | Модуляторы рецепторов, активируемых пролифераторами пероксисом |
| GB2460784A (en) * | 2007-03-07 | 2009-12-16 | Dong A Pharmtech Co Ltd | Novel phenylpropionic acid derivatives as peroxisome proliferator-activated gamma receptor modulators,method of the same,and pharmaceutical composition |
| DE102008007400A1 (de) * | 2008-02-04 | 2009-08-06 | Bayer Healthcare Ag | Substituierte Furane und ihre Verwendung |
| AU2009236877B2 (en) | 2008-04-15 | 2014-01-23 | Nippon Chemiphar Co., Ltd. | Activator for peroxisome proliferator-activated receptor |
| CN101643451B (zh) * | 2008-08-07 | 2013-03-06 | 浙江海正药业股份有限公司 | 过氧化物酶增殖物激活受体亚型δ类激动剂化合物及其制备方法 |
| WO2012030165A2 (ko) | 2010-08-31 | 2012-03-08 | 서울대학교산학협력단 | P P A R δ 활성물질의 태자재프로그래밍용도 |
| US10118922B2 (en) * | 2013-03-14 | 2018-11-06 | Janssen Pharmaceutica Nv | GPR120 agonists for the treatment of type II diabetes |
| CN105209450B (zh) * | 2013-03-14 | 2017-10-20 | 美国陶氏益农公司 | 具有一定农药效用的分子和中间体、组合物及其相关方法 |
| US11634387B2 (en) | 2019-09-26 | 2023-04-25 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| WO2022189856A1 (en) * | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9817118D0 (en) | 1998-08-07 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
| RU2267484C2 (ru) | 1999-04-28 | 2006-01-10 | Авентис Фарма Дойчланд Гмбх | Производные диариловой кислоты и фармацевтическая композиция на их основе |
-
2001
- 2001-05-11 GB GBGB0111523.7A patent/GB0111523D0/en not_active Ceased
-
2002
- 2002-05-09 KR KR10-2003-7014660A patent/KR20040023600A/ko not_active Withdrawn
- 2002-05-09 CZ CZ20033064A patent/CZ20033064A3/cs unknown
- 2002-05-09 WO PCT/GB2002/002152 patent/WO2002092590A1/en not_active Ceased
- 2002-05-09 CN CNA028096940A patent/CN1507442A/zh active Pending
- 2002-05-09 PL PL02367478A patent/PL367478A1/xx not_active Application Discontinuation
- 2002-05-09 AT AT02722506T patent/ATE301649T1/de not_active IP Right Cessation
- 2002-05-09 HU HU0304051A patent/HUP0304051A3/hu unknown
- 2002-05-09 MX MXPA03010285A patent/MXPA03010285A/es unknown
- 2002-05-09 IL IL15833202A patent/IL158332A0/xx unknown
- 2002-05-09 DE DE60205481T patent/DE60205481T2/de not_active Expired - Fee Related
- 2002-05-09 CA CA002446797A patent/CA2446797A1/en not_active Abandoned
- 2002-05-09 BR BR0209468-1A patent/BR0209468A/pt not_active IP Right Cessation
- 2002-05-09 US US10/476,194 patent/US7091237B2/en not_active Expired - Fee Related
- 2002-05-09 JP JP2002589475A patent/JP2004534035A/ja active Pending
- 2002-05-09 ES ES02722506T patent/ES2247322T3/es not_active Expired - Lifetime
- 2002-05-09 EP EP02722506A patent/EP1392674B1/en not_active Expired - Lifetime
-
2003
- 2003-10-27 ZA ZA200308352A patent/ZA200308352B/en unknown
- 2003-11-10 NO NO20034986A patent/NO20034986L/no not_active Application Discontinuation
- 2003-11-10 CO CO03099078A patent/CO5540343A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0304051A2 (hu) | 2004-04-28 |
| ATE301649T1 (de) | 2005-08-15 |
| US20040157890A1 (en) | 2004-08-12 |
| NO20034986D0 (no) | 2003-11-10 |
| BR0209468A (pt) | 2004-08-03 |
| GB0111523D0 (en) | 2001-07-04 |
| EP1392674A1 (en) | 2004-03-03 |
| NO20034986L (no) | 2003-11-10 |
| CN1507442A (zh) | 2004-06-23 |
| PL367478A1 (en) | 2005-02-21 |
| DE60205481T2 (de) | 2006-05-24 |
| KR20040023600A (ko) | 2004-03-18 |
| CZ20033064A3 (cs) | 2004-02-18 |
| EP1392674B1 (en) | 2005-08-10 |
| ZA200308352B (en) | 2005-01-27 |
| CA2446797A1 (en) | 2002-11-21 |
| HUP0304051A3 (en) | 2005-11-28 |
| JP2004534035A (ja) | 2004-11-11 |
| ES2247322T3 (es) | 2006-03-01 |
| WO2002092590A1 (en) | 2002-11-21 |
| MXPA03010285A (es) | 2004-03-09 |
| US7091237B2 (en) | 2006-08-15 |
| DE60205481D1 (de) | 2005-09-15 |
| CO5540343A2 (es) | 2005-07-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL158332A0 (en) | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | |
| DK1452524T3 (da) | "2-oxo-1-pyrrolidinderivat og dets farmaceutiske anvendelser" | |
| TW200716572A (en) | Peroxisome proliferator activated receptor alpha agonists | |
| CA2377126A1 (en) | Thiazole and oxazole derivatives and their pharmaceutical use | |
| MY138352A (en) | Benzothiazole derivatives | |
| NZ514574A (en) | Novel method of treatment | |
| IL213809A0 (en) | Use of derivatives of n-phenylpiperazin-1-yl-acetamide for the preparation of a pharmaceutical compositions for treatment of diabetes related conditions | |
| IL159002A0 (en) | Modulators of peroxisome proliferator activated receptors (ppar) | |
| IL158873A0 (en) | Modulators of peroxisome proliferator activated receptors | |
| DK1349843T3 (da) | Thiazol- og oxazolderivater som aktivatorer af human peroxisom profilerator-aktiverede receptorer | |
| MXPA04003439A (es) | Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc. | |
| PL375964A1 (en) | Use of indolyl derivatives for the manufacture of a medicament for the treatment allergic rhinitis | |
| MXPA05006889A (es) | Compuestos aromaticos como agentes anti-inflamatorios, inmunomoduladores y anti-proliferativos. | |
| HK1049618A1 (zh) | 骨質形成調節 | |
| WO2005077926A3 (en) | Benzofuran and benzothiophene derivatives useful for the treatment of cardiovascular disease | |
| WO2001068063A3 (en) | Novel use of (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts | |
| HK1063634A (en) | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | |
| DE60026559D1 (de) | Arzneimittel gegen essstörungen | |
| SE9900438D0 (sv) | The pharmacological use of certian cystine derivatives | |
| WO2003004019A8 (en) | Use of heterocyclic and benzoheterocyclic polyamides structurally related to the natural antibiotic distamycin a for the treatment of beta-thalassaemia | |
| ITMI20022594A1 (it) | Combinazione terapeutica per la cura dell'ipertensione. | |
| FR2804867B1 (fr) | Application de derives de xanthine pour la preparation d'un medicament destine a la prevention ou au traitement de l'osteoporose | |
| SI1148881T1 (sl) | Uporaba derivatov pridazino - (4,5-(b))-indol-1-acetamida za pripravo zdravil za bolezni, povezane z disfunkcijo perifernih benzodiazepinskih receptorjev |