IL153177A0 - Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors - Google Patents

Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors

Info

Publication number
IL153177A0
IL153177A0 IL15317701A IL15317701A IL153177A0 IL 153177 A0 IL153177 A0 IL 153177A0 IL 15317701 A IL15317701 A IL 15317701A IL 15317701 A IL15317701 A IL 15317701A IL 153177 A0 IL153177 A0 IL 153177A0
Authority
IL
Israel
Prior art keywords
topoisomerase
inhibitors
distamycin derivatives
acryloyl distamycin
pharmaceutical compositions
Prior art date
Application number
IL15317701A
Other languages
English (en)
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of IL153177A0 publication Critical patent/IL153177A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL15317701A 2000-06-23 2001-06-20 Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors IL153177A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0015444.3A GB0015444D0 (en) 2000-06-23 2000-06-23 Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
PCT/EP2001/007059 WO2001097789A2 (fr) 2000-06-23 2001-06-20 Therapie combinee contre des tumeurs a base de derives de distamycine acryloyle et d'inhibiteurs de la topoisomerase i et ii

Publications (1)

Publication Number Publication Date
IL153177A0 true IL153177A0 (en) 2003-06-24

Family

ID=9894285

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15317701A IL153177A0 (en) 2000-06-23 2001-06-20 Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors

Country Status (27)

Country Link
US (1) US20030162722A1 (fr)
EP (1) EP1292290B1 (fr)
JP (1) JP2003535890A (fr)
KR (1) KR100853955B1 (fr)
CN (1) CN1241573C (fr)
AT (1) ATE323483T1 (fr)
AU (2) AU2001278463B2 (fr)
BR (1) BR0111813A (fr)
CA (1) CA2411172C (fr)
CZ (1) CZ20024155A3 (fr)
DE (1) DE60118914T2 (fr)
DK (1) DK1292290T3 (fr)
EA (1) EA006684B1 (fr)
EE (1) EE05319B1 (fr)
ES (1) ES2261448T3 (fr)
GB (1) GB0015444D0 (fr)
HK (1) HK1054334B (fr)
HU (1) HUP0301257A2 (fr)
IL (1) IL153177A0 (fr)
MX (1) MXPA02012163A (fr)
NO (1) NO329783B1 (fr)
NZ (1) NZ523000A (fr)
PL (1) PL200503B1 (fr)
PT (1) PT1292290E (fr)
SK (1) SK287549B6 (fr)
WO (1) WO2001097789A2 (fr)
ZA (1) ZA200209834B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
BR0215454A (pt) * 2002-01-02 2004-11-23 Pharmacia Italia Spa Terapia combinada contra tumores, comprendendo derivados de acriloil-distamicina substituìdos e inibidores de proteìna cinase (serina/treonina cinase)
CN100438913C (zh) * 2004-11-22 2008-12-03 山东蓝金生物工程有限公司 一种抗癌药物组合物
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
CN103080125A (zh) 2010-07-02 2013-05-01 安吉奥开米公司 用于治疗性结合物的短且含d氨基酸的多肽及其使用
CN109718228A (zh) * 2017-10-30 2019-05-07 沈阳药科大学 米托蒽醌的抗肿瘤淋巴转移作用及其药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) * 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806692D0 (en) * 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors

Also Published As

Publication number Publication date
EA200300060A1 (ru) 2003-04-24
DE60118914D1 (de) 2006-05-24
NO20026078L (no) 2002-12-18
CA2411172A1 (fr) 2001-12-27
HK1054334B (zh) 2006-09-22
KR100853955B1 (ko) 2008-08-25
NZ523000A (en) 2005-12-23
KR20030019448A (ko) 2003-03-06
NO329783B1 (no) 2010-12-13
SK18332002A3 (sk) 2003-07-01
US20030162722A1 (en) 2003-08-28
CZ20024155A3 (cs) 2003-04-16
NO20026078D0 (no) 2002-12-18
EP1292290A2 (fr) 2003-03-19
BR0111813A (pt) 2003-05-20
HK1054334A1 (en) 2003-11-28
PL360297A1 (en) 2004-09-06
WO2001097789A2 (fr) 2001-12-27
SK287549B6 (sk) 2011-01-04
AU7846301A (en) 2002-01-02
WO2001097789A3 (fr) 2002-05-16
EE05319B1 (et) 2010-08-16
ATE323483T1 (de) 2006-05-15
ZA200209834B (en) 2003-12-04
EE200200681A (et) 2004-06-15
EA006684B1 (ru) 2006-02-24
ES2261448T3 (es) 2006-11-16
MXPA02012163A (es) 2003-04-25
CN1437474A (zh) 2003-08-20
CN1241573C (zh) 2006-02-15
EP1292290B1 (fr) 2006-04-19
HUP0301257A2 (hu) 2003-08-28
PL200503B1 (pl) 2009-01-30
DK1292290T3 (da) 2006-07-10
DE60118914T2 (de) 2006-12-21
PT1292290E (pt) 2006-08-31
CA2411172C (fr) 2009-11-17
AU2001278463B2 (en) 2006-02-23
GB0015444D0 (en) 2000-08-16
JP2003535890A (ja) 2003-12-02

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees