IL150789A0 - Multipotent neural stem cells from peripheral tissues and uses thereof - Google Patents
Multipotent neural stem cells from peripheral tissues and uses thereofInfo
- Publication number
- IL150789A0 IL150789A0 IL15078901A IL15078901A IL150789A0 IL 150789 A0 IL150789 A0 IL 150789A0 IL 15078901 A IL15078901 A IL 15078901A IL 15078901 A IL15078901 A IL 15078901A IL 150789 A0 IL150789 A0 IL 150789A0
- Authority
- IL
- Israel
- Prior art keywords
- stem cells
- neural stem
- peripheral tissues
- multipotent neural
- multipotent
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/195—Heregulin, neu differentiation factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49042200A | 2000-01-24 | 2000-01-24 | |
US09/670,049 US6787355B1 (en) | 1996-08-26 | 2000-09-25 | Multipotent neural stem cells from peripheral tissues and uses thereof |
PCT/CA2001/000047 WO2001053461A1 (fr) | 2000-01-24 | 2001-01-24 | Cellules embryonnaires neuronales multipotentes issues de tissus peripheriques et utilisations correspondantes |
Publications (1)
Publication Number | Publication Date |
---|---|
IL150789A0 true IL150789A0 (en) | 2003-02-12 |
Family
ID=27050050
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15078901A IL150789A0 (en) | 2000-01-24 | 2001-01-24 | Multipotent neural stem cells from peripheral tissues and uses thereof |
IL150789A IL150789A (en) | 2000-01-24 | 2002-07-17 | Multipotent neural stem cells from peripheral tissues and uses thereof |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL150789A IL150789A (en) | 2000-01-24 | 2002-07-17 | Multipotent neural stem cells from peripheral tissues and uses thereof |
Country Status (9)
Country | Link |
---|---|
US (3) | US6787355B1 (fr) |
EP (1) | EP1255813B1 (fr) |
JP (1) | JP2003525034A (fr) |
AT (1) | ATE439429T1 (fr) |
AU (2) | AU2001228216B2 (fr) |
CA (1) | CA2398239A1 (fr) |
DE (1) | DE60139543D1 (fr) |
IL (2) | IL150789A0 (fr) |
WO (1) | WO2001053461A1 (fr) |
Families Citing this family (65)
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US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
US7544509B2 (en) | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
JP2004529621A (ja) | 2001-02-14 | 2004-09-30 | ティー ファークト,レオ | 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞 |
US7838292B1 (en) * | 2001-03-29 | 2010-11-23 | University Of Louisville Research Foundation, Inc. | Methods for obtaining adult human olfactory progenitor cells |
WO2003060085A2 (fr) * | 2002-01-14 | 2003-07-24 | The Board Of Trustees Of The University Of Illinois | Nouvelles cellules souches neuronales, multipotentes, mammaliennes et compositions associees, procedes de preparation et procedes d'administration de ces preparations |
AUPS187202A0 (en) * | 2002-04-22 | 2002-05-30 | Griffith University | Method for culturing stem cells |
WO2004018652A2 (fr) * | 2002-08-16 | 2004-03-04 | Ulrich Drews | Procede permettant d'obtenir des cellules souches diploides pluripotentes et utilisation desdites cellules |
US7560276B2 (en) | 2003-06-27 | 2009-07-14 | Ethicon, Incorporated | Soft tissue repair and regeneration using postpartum-derived cells |
WO2004078944A2 (fr) | 2003-03-05 | 2004-09-16 | Maine Medical Center Research Institute | Compositions, methodes et necessaires en rapport avec la thrombine, signalisation de notch, stamatogenese et croissance de cellules souches |
CA2528248A1 (fr) * | 2003-06-06 | 2004-12-16 | The Hospital For Sick Children | Cellules souches de la crete neurale et leurs utilisations |
US7186557B2 (en) * | 2003-06-13 | 2007-03-06 | Isolagen Technologies, Inc. | Methods of producing neurons |
US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
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US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
US8426200B2 (en) | 2003-07-02 | 2013-04-23 | Regents Of The University Of Minnesota | Neuronal differentiation of stem cells |
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KR100768533B1 (ko) | 2004-11-30 | 2007-10-18 | 재단법인 한국원자력의학원 | 피부 진피로부터 신경전구세포를 유도하는 방법 및 중추또는 말초 신경계 손상 치료제 |
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PL1971681T3 (pl) * | 2005-12-16 | 2018-01-31 | Depuy Synthes Products Inc | Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej |
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US6001654A (en) | 1994-01-28 | 1999-12-14 | California Institute Of Technology | Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors |
US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
CA2253724A1 (fr) | 1996-04-26 | 1997-11-06 | Case Western Reserve University | Regeneration de la peau au moyen des cellules souches mesenchymateuses |
US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
WO1999056759A1 (fr) | 1998-05-07 | 1999-11-11 | University Of South Florida | Cellules de moelle osseuse comme source de neurones utile pour reparer la moelle epiniere et le cerveau |
NZ517002A (en) * | 1999-08-05 | 2004-06-25 | Mcl Llc | Multipotent adult stem cells and methods for isolation |
-
2000
- 2000-09-25 US US09/670,049 patent/US6787355B1/en not_active Expired - Fee Related
-
2001
- 2001-01-24 AT AT01942663T patent/ATE439429T1/de not_active IP Right Cessation
- 2001-01-24 DE DE60139543T patent/DE60139543D1/de not_active Expired - Lifetime
- 2001-01-24 IL IL15078901A patent/IL150789A0/xx unknown
- 2001-01-24 CA CA002398239A patent/CA2398239A1/fr not_active Abandoned
- 2001-01-24 JP JP2001553922A patent/JP2003525034A/ja active Pending
- 2001-01-24 US US10/181,508 patent/US20040033597A1/en not_active Abandoned
- 2001-01-24 WO PCT/CA2001/000047 patent/WO2001053461A1/fr active IP Right Grant
- 2001-01-24 AU AU2001228216A patent/AU2001228216B2/en not_active Ceased
- 2001-01-24 AU AU2821601A patent/AU2821601A/xx active Pending
- 2001-01-24 EP EP01942663A patent/EP1255813B1/fr not_active Expired - Lifetime
-
2002
- 2002-07-17 IL IL150789A patent/IL150789A/en not_active IP Right Cessation
-
2008
- 2008-05-05 US US12/149,616 patent/US20090142834A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001053461A1 (fr) | 2001-07-26 |
EP1255813B1 (fr) | 2009-08-12 |
AU2821601A (en) | 2001-07-31 |
AU2001228216B2 (en) | 2007-07-26 |
US20040033597A1 (en) | 2004-02-19 |
JP2003525034A (ja) | 2003-08-26 |
CA2398239A1 (fr) | 2001-07-26 |
EP1255813A1 (fr) | 2002-11-13 |
IL150789A (en) | 2010-12-30 |
ATE439429T1 (de) | 2009-08-15 |
US20090142834A1 (en) | 2009-06-04 |
DE60139543D1 (de) | 2009-09-24 |
WO2001053461A9 (fr) | 2002-01-03 |
US6787355B1 (en) | 2004-09-07 |
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