IL150789A0 - Multipotent neural stem cells from peripheral tissues and uses thereof - Google Patents

Multipotent neural stem cells from peripheral tissues and uses thereof

Info

Publication number
IL150789A0
IL150789A0 IL15078901A IL15078901A IL150789A0 IL 150789 A0 IL150789 A0 IL 150789A0 IL 15078901 A IL15078901 A IL 15078901A IL 15078901 A IL15078901 A IL 15078901A IL 150789 A0 IL150789 A0 IL 150789A0
Authority
IL
Israel
Prior art keywords
stem cells
neural stem
peripheral tissues
multipotent neural
multipotent
Prior art date
Application number
IL15078901A
Other languages
English (en)
Original Assignee
Univ Mcgill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mcgill filed Critical Univ Mcgill
Publication of IL150789A0 publication Critical patent/IL150789A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/195—Heregulin, neu differentiation factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
IL15078901A 2000-01-24 2001-01-24 Multipotent neural stem cells from peripheral tissues and uses thereof IL150789A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49042200A 2000-01-24 2000-01-24
US09/670,049 US6787355B1 (en) 1996-08-26 2000-09-25 Multipotent neural stem cells from peripheral tissues and uses thereof
PCT/CA2001/000047 WO2001053461A1 (fr) 2000-01-24 2001-01-24 Cellules embryonnaires neuronales multipotentes issues de tissus peripheriques et utilisations correspondantes

Publications (1)

Publication Number Publication Date
IL150789A0 true IL150789A0 (en) 2003-02-12

Family

ID=27050050

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15078901A IL150789A0 (en) 2000-01-24 2001-01-24 Multipotent neural stem cells from peripheral tissues and uses thereof
IL150789A IL150789A (en) 2000-01-24 2002-07-17 Multipotent neural stem cells from peripheral tissues and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL150789A IL150789A (en) 2000-01-24 2002-07-17 Multipotent neural stem cells from peripheral tissues and uses thereof

Country Status (9)

Country Link
US (3) US6787355B1 (fr)
EP (1) EP1255813B1 (fr)
JP (1) JP2003525034A (fr)
AT (1) ATE439429T1 (fr)
AU (2) AU2821601A (fr)
CA (1) CA2398239A1 (fr)
DE (1) DE60139543D1 (fr)
IL (2) IL150789A0 (fr)
WO (1) WO2001053461A1 (fr)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
WO2002064748A2 (fr) 2001-02-14 2002-08-22 Furcht Leo T Cellules souches adultes totipotentes, sources de ces cellules, procedes d'obtention et de maintien de ces dernieres, procedes de differentiation de ces cellules, procedes d'utilisation correspondants et cellules derivees des cellules susmentionnees
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7544509B2 (en) 2000-01-24 2009-06-09 Mcgill University Method for preparing stem cell preparations
US7838292B1 (en) * 2001-03-29 2010-11-23 University Of Louisville Research Foundation, Inc. Methods for obtaining adult human olfactory progenitor cells
JP4623967B2 (ja) 2002-01-14 2011-02-02 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ 幹細胞の移動および増殖を促進するための修飾されたピリミジン化合物の使用
AUPS187202A0 (en) * 2002-04-22 2002-05-30 Griffith University Method for culturing stem cells
WO2004018652A2 (fr) * 2002-08-16 2004-03-04 Ulrich Drews Procede permettant d'obtenir des cellules souches diploides pluripotentes et utilisation desdites cellules
WO2004078944A2 (fr) 2003-03-05 2004-09-16 Maine Medical Center Research Institute Compositions, methodes et necessaires en rapport avec la thrombine, signalisation de notch, stamatogenese et croissance de cellules souches
WO2004108908A1 (fr) * 2003-06-06 2004-12-16 The Hospital For Sick Children Cellules souches de la crete neurale et leurs utilisations
US7186557B2 (en) * 2003-06-13 2007-03-06 Isolagen Technologies, Inc. Methods of producing neurons
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
JP5148873B2 (ja) * 2003-06-27 2013-02-20 エチコン、インコーポレイテッド 臍帯組織由来の分娩後細胞、及びその作成及び使用方法
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
WO2006071794A2 (fr) 2004-12-23 2006-07-06 Ethicon Incorporated Cellules postnatales derivees de tissus du cordon ombilical, et procedes de production et d'utilisation de celles-ci
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US8426200B2 (en) 2003-07-02 2013-04-23 Regents Of The University Of Minnesota Neuronal differentiation of stem cells
WO2005046596A2 (fr) 2003-11-04 2005-05-26 University Of Maryland Baltimore Milieu de culture de cellule souche et procede pour utiliser ledit milieu et les cellules
US20070248574A1 (en) * 2004-01-27 2007-10-25 Miller Freda D Methods of Making and Using Skin-Derived Stem Cells
FR2870854B1 (fr) * 2004-05-26 2010-12-31 Oreal Utilisation du lif en ingenierie cellulaire et tissulaire
US8080420B2 (en) 2004-10-22 2011-12-20 University Of Central Florida Research Foundation, Inc. Methods and products for biasing cellular development
KR100768533B1 (ko) 2004-11-30 2007-10-18 재단법인 한국원자력의학원 피부 진피로부터 신경전구세포를 유도하는 방법 및 중추또는 말초 신경계 손상 치료제
US20060153815A1 (en) * 2004-12-21 2006-07-13 Agnieszka Seyda Tissue engineering devices for the repair and regeneration of tissue
US20060166361A1 (en) * 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
US20060171930A1 (en) * 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
WO2006071802A2 (fr) 2004-12-23 2006-07-06 Ethicon Incorporated Traitement de l'ictus cerebral et d'autres troubles neurodegeneratifs aigus a base de cellules tirees de tissus puerperaux
DK1855700T3 (da) 2005-03-07 2014-01-13 Sanbio Inc Anvendelse af neuronale præcursorceller til behandling af læsioner i centralnervesystemet
US20070123448A1 (en) * 2005-11-23 2007-05-31 The Hospital For Sick Children Novel chemical entities affecting neuroblastoma tumor-initiating cells
ES2642844T3 (es) * 2005-12-16 2017-11-20 DePuy Synthes Products, Inc. Composiciones y métodos para inhibir una respuesta inmune adversa en el trasplante de histocompatibilidad que no coinciden
US8741638B2 (en) * 2005-12-19 2014-06-03 DePuy Synthes Products, LLC In vitro expansion of postpartum-derived cells in roller bottles
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
WO2007076522A2 (fr) * 2005-12-28 2007-07-05 Ethicon, Incorporated Traitement de maladies vasculaires peripheriques a l'aide de cellules derivees du post-partum
WO2007091790A1 (fr) * 2006-02-07 2007-08-16 Korea Institute Of Radiological & Medical Sciences Composition destinée au traitement d'une lésion du système nerveux central ou périphérique
AU2007289338A1 (en) * 2006-08-31 2008-03-06 The University Of Louisville Research Foundation, Inc. Transcription factors for differentiation of adult human olfactory progenitor cells
KR100825864B1 (ko) * 2006-09-21 2008-04-28 부산대학교 산학협력단 피부 유래 줄기세포를 함유하는 신경질환 치료용세포치료제
EP2087101A2 (fr) 2006-11-24 2009-08-12 Regents of the University of Minnesota Cellules progénitrices endothermiques
US8617882B2 (en) 2007-06-06 2013-12-31 The Hospital For Sick Children Skin-derived precursor cells and uses thereof
WO2009046335A1 (fr) * 2007-10-05 2009-04-09 Ethicon, Incorporated Réparation et régénération du tissu rénal au moyen de cellules provenant de tissus de cordon ombilical humain
US8236538B2 (en) 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
PL2745694T3 (pl) * 2008-06-18 2018-03-30 Basf Se Kompozycje chwastobójcze zawierające kwas 4-amino-3,6-dichloropirydyno-2-karboksylowy
US8748177B2 (en) 2008-09-30 2014-06-10 The Hospital For Sick Children Compositions for proliferation of cells and related methods
ES2569373T3 (es) 2008-10-31 2016-05-10 University Of Louisville Research Foundation, Inc. Células madre derivadas del epitelio olfativo y procedimientos para su utilización
SI2379087T1 (sl) * 2008-12-19 2015-01-30 DePuy Synthes Products, LLC Celice, izpeljane iz popkovniäśnega tkiva, za zdravljenje nevropatske boleäśine in spastiäśnosti
JP6095893B2 (ja) * 2008-12-19 2017-03-15 デピュイ・シンセス・プロダクツ・インコーポレイテッド 傷害後の神経組織の再生および修復
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
CA2747794C (fr) 2008-12-19 2018-10-30 Advanced Technologies And Regenerative Medicine, Llc Traitement des poumons et des maladies et troubles pulmonaires
AU2010229651B2 (en) * 2009-03-26 2014-05-08 Advanced Technologies And Regenerative Medicine, Llc Human umbilical cord tissue cells as therapy for Alzheimer' s disease
EP2625263B1 (fr) 2010-10-08 2020-03-11 Terumo BCT, Inc. Procédés et systèmes configurables pour la culture et la récolte de cellules dans un système de bioréacteur à fibres creuses
AU2012328582A1 (en) * 2011-10-26 2014-05-01 University Of Louisville Research Foundation, Inc. Methods and compositions for treating diabetes and other degenerative neuroendocrine diseases or disorders
CN104837987B (zh) 2011-12-23 2018-10-02 德普伊新特斯产品公司 人脐带组织来源的细胞的检测
US10357517B1 (en) 2012-10-01 2019-07-23 University Of South Florida Methods of treating epilepsy using neural stem cells that express nanog, SSEA-4, OCT-4, MIR-34B, MIR-34C and MIR-592
WO2015073918A1 (fr) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expansion de cellules dans un bioréacteur
EP3122866B1 (fr) 2014-03-25 2019-11-20 Terumo BCT, Inc. Remplacement passif de milieu
EP3198006B1 (fr) 2014-09-26 2021-03-24 Terumo BCT, Inc. Alimentation programmée
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
EP3464565A4 (fr) 2016-05-25 2020-01-01 Terumo BCT, Inc. Expansion cellulaire
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656842A1 (fr) 2017-03-31 2020-05-27 Terumo BCT, Inc. Expansion de cellules
WO2020045450A1 (fr) * 2018-08-31 2020-03-05 株式会社 資生堂 Procédé cosmétique

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328695A (en) * 1983-03-22 1994-07-12 Massachusetts Institute Of Technology Muscle morphogenic protein and use thereof
US5338839A (en) 1988-04-12 1994-08-16 Massachusetts Institute Of Technology DNA encoding nestin protein
US5834312A (en) 1990-01-29 1998-11-10 Hy-Gene, Inc. Process and media for the growth of human epithelia
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5217893A (en) * 1990-12-31 1993-06-08 The Johns Hopkins University Primary culture of olfactory neurons
CA2113118C (fr) 1991-07-08 2002-09-17 Samuel Weiss Nouvelles cellules souches sensibles au facteur de croissance qui peuvent proliferer in vitro
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
EP0658194A1 (fr) * 1992-07-27 1995-06-21 California Institute Of Technology Cellules souches neurales pluripotentes de mammifere
CA2147162C (fr) 1992-10-16 2002-04-30 Samuel Weiss Remyelinisation des neurones a l'aide de cellules souches neurales
DE69334344D1 (de) 1992-10-28 2010-11-18 Neurospheres Holding Ltd Biologische Faktoren und neuronale Stammzellen
JP3583778B2 (ja) 1993-01-29 2004-11-04 ニューロスフィアーズ ホウルディングス リミテッド 神経幹細胞の遺伝子修飾
US5426098A (en) * 1993-09-02 1995-06-20 Celtrix Pharmaceuticals, Inc. Increase in hematopoietic progenitor cells in peripheral blood by transforming growth factor beta
US6432711B1 (en) 1993-11-03 2002-08-13 Diacrin, Inc. Embryonic stem cells capable of differentiating into desired cell lines
DK0728194T3 (da) 1993-11-09 2003-04-22 Neurospheres Holdings Ltd In situ modifikation og manipulation af stamceller fra centralnervesystemet.
US6001654A (en) 1994-01-28 1999-12-14 California Institute Of Technology Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
CA2253724A1 (fr) 1996-04-26 1997-11-06 Case Western Reserve University Regeneration de la peau au moyen des cellules souches mesenchymateuses
US5753506A (en) 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
US6093531A (en) 1997-09-29 2000-07-25 Neurospheres Holdings Ltd. Generation of hematopoietic cells from multipotent neural stem cells
ES2246085T3 (es) 1998-05-07 2006-02-01 University Of South Florida Celulas de medula osea como fuente de neuronas util para reparar la medula espinal y el cerebro.
EP2348104A1 (fr) * 1999-08-05 2011-07-27 Mcl Llc Cellules souches adultes multipotentes et procédés d'isolation

Also Published As

Publication number Publication date
US20040033597A1 (en) 2004-02-19
AU2821601A (en) 2001-07-31
IL150789A (en) 2010-12-30
AU2001228216B2 (en) 2007-07-26
WO2001053461A9 (fr) 2002-01-03
JP2003525034A (ja) 2003-08-26
US20090142834A1 (en) 2009-06-04
CA2398239A1 (fr) 2001-07-26
US6787355B1 (en) 2004-09-07
ATE439429T1 (de) 2009-08-15
EP1255813A1 (fr) 2002-11-13
WO2001053461A1 (fr) 2001-07-26
DE60139543D1 (de) 2009-09-24
EP1255813B1 (fr) 2009-08-12

Similar Documents

Publication Publication Date Title
IL150789A (en) Multipotent neural stem cells from peripheral tissues and uses thereof
WO2003010243A3 (fr) Cellules souches pluripotentes provenant de tissus peripheriques et leurs utilisations
SG152273A1 (en) Pdx1 expressing endoderm
MX2009009225A (es) Endodermo definitivo.
HK1049350A1 (en) Multipotent adult stem cells and methods for isolation
WO2002012452A3 (fr) Cellules souches, procedes et utilisations les concernant
WO2000047720A3 (fr) Cellules progenitrices de pancreas et procedes et utilisations associees
WO2003024406A3 (fr) Cellules souches de follicules pileux exprimant la nestine
SG169324A1 (en) Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
ATE382681T1 (de) Verbesserung der herzfunktion durch transplantation mesenchymaler stammzellen
ATE328067T1 (de) Isolierung von mesenchymalen stammzellen und deren verwendung
SG163588A1 (en) Methods for identifying agents and conditions that modulate neurogenesis
MX2009014273A (es) Metodos y composiciones para expansion e implantacion optimizadas de celulas madre mesenquimales.
WO2004015077A3 (fr) Compositions et methodes de differentiation neuronale de cellules souches embryonnaires humaines
WO2001021766A3 (fr) Procedes et dispositifs permettant d'obtenir des cellules de lignee non hematopoietique a partir de cellules de progeniteurs hematopoietiques
WO2006070370A3 (fr) Systemes de culture de cellules souches
WO2002064748A3 (fr) Cellules souches adultes totipotentes, sources de ces cellules, procedes d'obtention et de maintien de ces dernieres, procedes de differentiation de ces cellules, procedes d'utilisation correspondants et cellules derivees des cellules susmentionnees
EA200601187A1 (ru) Стволовые клетки
WO2006047743A8 (fr) Cellules souches adultes de porc
EP1465983A4 (fr) Cellules souches endotheliales, populations, procedes d'isolement et d'utilisation associes
WO2005030040A8 (fr) Identification et isolation de cellules souches hematopoietiques
WO2002034890A3 (fr) Cellules souches pluripotentes
EP2377922A3 (fr) Endoderme exprimant PDX1
WO2004030628A3 (fr) Cellules souches derivees de la moelle osseuse adulte
WO2002062967A3 (fr) Cellules souches o-2a pluripotentes issues de la neurohypophyse