IL148930A0 - Methods for generating databases and databases for identifying polymorphic genetic markers - Google Patents

Methods for generating databases and databases for identifying polymorphic genetic markers

Info

Publication number
IL148930A0
IL148930A0 IL14893000A IL14893000A IL148930A0 IL 148930 A0 IL148930 A0 IL 148930A0 IL 14893000 A IL14893000 A IL 14893000A IL 14893000 A IL14893000 A IL 14893000A IL 148930 A0 IL148930 A0 IL 148930A0
Authority
IL
Israel
Prior art keywords
nucleic acid
databases
obtaining
mass spectrum
detecting
Prior art date
Application number
IL14893000A
Other languages
English (en)
Original Assignee
Sequenom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/663,968 external-priority patent/US7917301B1/en
Application filed by Sequenom Inc filed Critical Sequenom Inc
Publication of IL148930A0 publication Critical patent/IL148930A0/xx

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/50—Compression of genetic data
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Databases & Information Systems (AREA)
  • Bioethics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Ecology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
IL14893000A 1999-10-13 2000-10-13 Methods for generating databases and databases for identifying polymorphic genetic markers IL148930A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15917699P 1999-10-13 1999-10-13
US21725100P 2000-07-10 2000-07-10
US21765800P 2000-07-10 2000-07-10
US09/663,968 US7917301B1 (en) 2000-09-19 2000-09-19 Method and device for identifying a biological sample
PCT/US2000/028413 WO2001027857A2 (en) 1999-10-13 2000-10-13 Methods for generating databases and databases for identifying polymorphic genetic markers

Publications (1)

Publication Number Publication Date
IL148930A0 true IL148930A0 (en) 2002-09-12

Family

ID=27496366

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14893000A IL148930A0 (en) 1999-10-13 2000-10-13 Methods for generating databases and databases for identifying polymorphic genetic markers

Country Status (9)

Country Link
EP (2) EP2088209B1 (ko)
JP (2) JP2003519829A (ko)
KR (1) KR20020064298A (ko)
AT (1) ATE444532T1 (ko)
AU (1) AU776811C (ko)
CA (1) CA2387035A1 (ko)
DE (1) DE60043076D1 (ko)
IL (1) IL148930A0 (ko)
WO (1) WO2001027857A2 (ko)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020009394A1 (en) 1999-04-02 2002-01-24 Hubert Koster Automated process line
US7917301B1 (en) * 2000-09-19 2011-03-29 Sequenom, Inc. Method and device for identifying a biological sample
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
AU2002348099A1 (en) 2001-10-26 2003-05-06 Sequenom Inc. Resin dispensing device
WO2003056328A1 (en) * 2001-12-21 2003-07-10 Smithkline Beecham Corporation High throughput correlation of polymorphic forms with multiple phenotypes within clinical populations
CA2508726A1 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US7468248B2 (en) 2002-12-31 2008-12-23 Cargill, Incorporated Methods and systems for inferring bovine traits
JP4741458B2 (ja) 2003-01-16 2011-08-03 カプロテック・バイオアナリティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 捕獲化合物、その収集物ならびにプロテオームおよび複合組成物を分析するための方法
US20060149502A1 (en) * 2003-02-27 2006-07-06 Takamasa Kato Information processing system using base sequence relevant information
AU2004219665A1 (en) * 2003-03-07 2004-09-23 Sequenom, Inc. Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods
JP2004287619A (ja) * 2003-03-19 2004-10-14 Ntt Data Corp 疫学情報管理装置、疫学情報管理方法、および、プログラム
EP1660680B1 (en) 2003-07-31 2009-03-11 Sequenom, Inc. Methods for high level multiplexed polymerase chain reactions and homogeneous mass extension reactions for genotyping of polymorphisms
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
US7608394B2 (en) * 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
WO2005098050A2 (en) 2004-03-26 2005-10-20 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
CA2616281C (en) 2005-07-21 2014-04-22 Isis Pharmaceuticals, Inc. Methods for rapid identification and quantitation of mitochondrial dna variants
JP2007102709A (ja) * 2005-10-07 2007-04-19 Toshiba Corp 遺伝子診断用のマーカー選定プログラム、該プログラムを実行する装置及びシステム、並びに遺伝子診断システム
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US20080228698A1 (en) 2007-03-16 2008-09-18 Expanse Networks, Inc. Creation of Attribute Combination Databases
JP5030166B2 (ja) 2007-05-01 2012-09-19 独立行政法人産業技術総合研究所 レーザー脱離イオン化質量分析に使用される試料支持用基板の試験方法
JP5036042B2 (ja) * 2007-05-28 2012-09-26 株式会社島津製作所 質量分析サンプルの調製方法、リボ核酸のイオン化方法、リボ核酸の質量分析方法、及び細胞由来の低分子リボ核酸の質量分析方法
US20100112590A1 (en) 2007-07-23 2010-05-06 The Chinese University Of Hong Kong Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment
PT2557517T (pt) * 2007-07-23 2023-01-04 Univ Hong Kong Chinese Determinação de um desequilíbrio de sequências de ácido nucleico
US20090043752A1 (en) 2007-08-08 2009-02-12 Expanse Networks, Inc. Predicting Side Effect Attributes
US7917438B2 (en) 2008-09-10 2011-03-29 Expanse Networks, Inc. System for secure mobile healthcare selection
US8200509B2 (en) 2008-09-10 2012-06-12 Expanse Networks, Inc. Masked data record access
US8108406B2 (en) 2008-12-30 2012-01-31 Expanse Networks, Inc. Pangenetic web user behavior prediction system
EP3276526A1 (en) 2008-12-31 2018-01-31 23Andme, Inc. Finding relatives in a database
DE112010004125A5 (de) * 2009-10-21 2012-11-22 Basf Plant Science Company Gmbh Verfahren zur erzeugung von biomarker-referenzpattern
WO2013070634A1 (en) * 2011-11-07 2013-05-16 Ingenuity Systems, Inc. Methods and systems for identification of causal genomic variants
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
JP6090201B2 (ja) * 2014-02-19 2017-03-08 株式会社島津製作所 マススペクトルデータ処理装置及びマススペクトルデータ処理方法
CA2946289C (en) * 2014-03-25 2018-08-07 Five3 Genomics, Llc Systems and methods for rna analysis in functional confirmation of cancer mutations
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
GB201518391D0 (en) 2015-10-16 2015-12-02 Micromass Ltd Processing mass spectral data
US10991185B1 (en) 2020-07-20 2021-04-27 Abbott Laboratories Digital pass verification systems and methods
CN114023379B (zh) * 2021-12-31 2022-05-13 浙江迪谱诊断技术有限公司 一种确定基因型的方法及装置
CN114755289A (zh) * 2022-03-25 2022-07-15 浙江迪谱诊断技术有限公司 一种核酸质谱盐离子干扰评价方法

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB2236186B (en) 1989-08-22 1994-01-05 Finnigan Mat Gmbh Process and device for laser desorption of analyte molecular ions, especially of biomolecules
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
US5436150A (en) 1992-04-03 1995-07-25 The Johns Hopkins University Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease
US5700672A (en) 1992-07-23 1997-12-23 Stratagene Purified thermostable pyrococcus furiousus DNA ligase
US5503980A (en) 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
US5422253A (en) 1992-12-07 1995-06-06 Wisconsin Alumni Research Foundation Method of site specific nucleic acid cleavage
EP1262564A3 (en) 1993-01-07 2004-03-31 Sequenom, Inc. Dna sequencing by mass spectrometry
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
CA2158642A1 (en) 1993-03-19 1994-09-29 Hubert Koster Dna sequencing by mass spectrometry via exonuclease degradation
US5604098A (en) 1993-03-24 1997-02-18 Molecular Biology Resources, Inc. Methods and materials for restriction endonuclease applications
CA2122203C (en) 1993-05-11 2001-12-18 Melinda S. Fraiser Decontamination of nucleic acid amplification reactions
US5714330A (en) 1994-04-04 1998-02-03 Lynx Therapeutics, Inc. DNA sequencing by stepwise ligation and cleavage
US5858705A (en) 1995-06-05 1999-01-12 Human Genome Sciences, Inc. Polynucleotides encoding human DNA ligase III and methods of using these polynucleotides
US5874283A (en) 1995-05-30 1999-02-23 John Joseph Harrington Mammalian flap-specific endonuclease
DK0843735T4 (da) 1995-07-11 2007-01-22 Univ College Cork Nat Univ Ie Glycolasemedieret påvisning af kendte nukleotidsekvenser
US6090606A (en) 1996-01-24 2000-07-18 Third Wave Technologies, Inc. Cleavage agents
WO1997037041A2 (en) 1996-03-18 1997-10-09 Sequenom, Inc. Dna sequencing by mass spectrometry
WO1997040462A2 (en) * 1996-04-19 1997-10-30 Spectra Biomedical, Inc. Correlating polymorphic forms with multiple phenotypes
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
WO1997047766A1 (en) * 1996-06-10 1997-12-18 University Of Utah Research Foundation Rapid, accurate identification of dna sequence variants by electrospray mass spectrometry
US5777324A (en) 1996-09-19 1998-07-07 Sequenom, Inc. Method and apparatus for maldi analysis
WO1998012355A1 (en) * 1996-09-19 1998-03-26 Genetrace Systems Methods of preparing nucleic acids for mass spectrometric analysis
ATE259056T1 (de) 1996-11-06 2004-02-15 Sequenom Inc Verfahren zur massenspektrometrie
US6024925A (en) 1997-01-23 2000-02-15 Sequenom, Inc. Systems and methods for preparing low volume analyte array elements
WO1998020019A1 (en) 1996-11-06 1998-05-14 Sequenom, Inc. Compositions and methods for immobilizing nucleic acids to solid supports
EP0960214A4 (en) * 1996-12-06 2004-08-04 Urocor Inc PATHOLOGICAL DIAGNOSIS USING RNA MESSENGER PROFILES
US6059724A (en) * 1997-02-14 2000-05-09 Biosignal, Inc. System for predicting future health
EP0985148A4 (en) * 1997-05-28 2004-03-10 Inst Medical W & E Hall DIAGNOSIS OF NUCLEIC ACIDS BY MASS SPECTROMETRY, MASS SEPARATION AND BASE-SPECIFIC CLEAVING
US5976806A (en) 1997-06-25 1999-11-02 Pioneer Hi-Bred International, Inc. DNA ligase assay
DE69823206T2 (de) * 1997-07-25 2004-08-19 Affymetrix, Inc. (a Delaware Corp.), Santa Clara Verfahren zur herstellung einer bio-informatik-datenbank
US5888795A (en) 1997-09-09 1999-03-30 Becton, Dickinson And Company Thermostable uracil DNA glycosylase and methods of use
DE19754482A1 (de) * 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
WO1999030167A1 (fr) * 1997-12-06 1999-06-17 Genox Research, Inc. Systeme de gestion de donnees-echantillons
ES2246546T3 (es) 1997-12-12 2006-02-16 Digene Corporation Valoracion de enfermedades relacionadas con el virus de papiloma humano.
US6054276A (en) 1998-02-23 2000-04-25 Macevicz; Stephen C. DNA restriction site mapping
US6132476A (en) 1998-04-20 2000-10-17 Southern Mills, Inc. Flame and shrinkage resistant fabric blends and method for making same
DE69804143T2 (de) 1998-04-22 2002-08-01 Entpr Ie Trd As Bioresearch Ie Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
US6099553A (en) 1998-05-21 2000-08-08 Applied Medical Resources Corporation Suture clinch
GB9904585D0 (en) * 1999-02-26 1999-04-21 Gemini Research Limited Clinical and diagnostic database
US7493698B2 (en) 2006-12-14 2009-02-24 Hsin-Chih Chung Lee Keyless clamp device for reciprocating saw
US9720195B2 (en) 2010-04-30 2017-08-01 Corning Optical Communications LLC Apparatuses and related components and methods for attachment and release of fiber optic housings to and from an equipment rack

Also Published As

Publication number Publication date
WO2001027857A9 (en) 2002-12-05
AU1084801A (en) 2001-04-23
KR20020064298A (ko) 2002-08-07
AU776811C (en) 2005-07-28
EP2088209A1 (en) 2009-08-12
JP2003519829A (ja) 2003-06-24
ATE444532T1 (de) 2009-10-15
WO2001027857A3 (en) 2002-10-03
EP2088209B1 (en) 2017-05-31
EP1261932A2 (en) 2002-12-04
AU776811B2 (en) 2004-09-23
CA2387035A1 (en) 2001-04-19
DE60043076D1 (de) 2009-11-12
JP2004158005A (ja) 2004-06-03
WO2001027857A2 (en) 2001-04-19
EP1261932B1 (en) 2009-09-30

Similar Documents

Publication Publication Date Title
IL148930A0 (en) Methods for generating databases and databases for identifying polymorphic genetic markers
US6403319B1 (en) Analysis of sequence tags with hairpin primers
CY1118000T1 (el) Διαδικασια υψηλης παροχης για αναλυση μεθυλιωσης dna
NO20005311D0 (no) FremgangsmÕte til karakterisering av nukleinsyremolekyler som innbefatter dannelse av utvidbare oppstrøms DNA fragmenter som resulterer fra spalting av nukleinsyre pÕ et abasisk sete
WO2005098050A3 (en) Base specific cleavage of methylation-specific amplification products in combination with mass analysis
DK1330546T3 (da) Fremgangsmåde til amplifikation og eventuel karakterisering af nucleinsyrer
WO2005026329A3 (en) Methods for identifying target nucleic acid molecules
DE60034878D1 (de) Verfahren zur Amplifizierung einer Nukleinsäuresequenz unter Verwendung eines chimären Primers
WO1999051774A3 (en) A method for obtaining a plant with a genetic lesion in a gene sequence
GB9903578D0 (en) Detection system
WO2001032922A3 (en) Methods for detection of a target nucleic acid sequence
EP1362929A3 (en) Methods for genotyping
WO2006017083A3 (en) Methods and compositions for phenotype identification based on nucleic acid methylation
US10000799B2 (en) Methods of sequencing with linked fragments
WO2004008841A3 (en) Dna fingerprinting for cannabis sativa (marijuana) using short tandem repeat (str) markers
Osman et al. Enhanced mismatch selectivity of t4 dna ligase far above the probe: Target duplex dissociation temperature
DE10104937B4 (de) Fluoreszenzpolarisation 2
CA2387148A1 (en) Method for distinguishing 5-position methylation changes
WO2002061140A3 (en) Competitive population normalization for comparative analysis of nucleic acid samples
WO2008009365A3 (en) A method for determining the methylation rate of a nucleic acid
JP2006075126A (ja) 一塩基変異を検出する方法および検出用プローブ
JP2020516317A (ja) 非線形増幅率を示すスイッチ様等温ｄｎａ増幅
WO2001044504A3 (en) Method for detecting methylated cpg-containing nucleic acid
RU2800778C2 (ru) Применение высокотермостойкого cas-белка и способ и набор реактивов для обнаружения целевой молекулы нуклеиновой кислоты
WO2001032909A3 (en) Method of detecting the presence or absence of specific genes