DE60043076D1 - Verfahren zur identifizierung von polymorphen genetischen markern - Google Patents
Verfahren zur identifizierung von polymorphen genetischen markernInfo
- Publication number
- DE60043076D1 DE60043076D1 DE60043076T DE60043076T DE60043076D1 DE 60043076 D1 DE60043076 D1 DE 60043076D1 DE 60043076 T DE60043076 T DE 60043076T DE 60043076 T DE60043076 T DE 60043076T DE 60043076 D1 DE60043076 D1 DE 60043076D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- obtaining
- mass spectrum
- detecting
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/40—Population genetics; Linkage disequilibrium
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
- G16B50/50—Compression of genetic data
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioethics (AREA)
- Databases & Information Systems (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Ecology (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15917699P | 1999-10-13 | 1999-10-13 | |
US21725100P | 2000-07-10 | 2000-07-10 | |
US21765800P | 2000-07-10 | 2000-07-10 | |
US09/663,968 US7917301B1 (en) | 2000-09-19 | 2000-09-19 | Method and device for identifying a biological sample |
PCT/US2000/028413 WO2001027857A2 (en) | 1999-10-13 | 2000-10-13 | Methods for generating databases and databases for identifying polymorphic genetic markers |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60043076D1 true DE60043076D1 (de) | 2009-11-12 |
Family
ID=27496366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60043076T Expired - Lifetime DE60043076D1 (de) | 1999-10-13 | 2000-10-13 | Verfahren zur identifizierung von polymorphen genetischen markern |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP2088209B1 (de) |
JP (2) | JP2003519829A (de) |
KR (1) | KR20020064298A (de) |
AT (1) | ATE444532T1 (de) |
AU (1) | AU776811C (de) |
CA (1) | CA2387035A1 (de) |
DE (1) | DE60043076D1 (de) |
IL (1) | IL148930A0 (de) |
WO (1) | WO2001027857A2 (de) |
Families Citing this family (42)
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US20020009394A1 (en) | 1999-04-02 | 2002-01-24 | Hubert Koster | Automated process line |
US7917301B1 (en) * | 2000-09-19 | 2011-03-29 | Sequenom, Inc. | Method and device for identifying a biological sample |
US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
US7159740B2 (en) | 2001-10-26 | 2007-01-09 | Sequenom, Inc. | Method and apparatus for parallel dispensing of defined volumes of solid particles |
AU2002357871A1 (en) * | 2001-12-21 | 2003-07-15 | Smithkline Beecham Corporation | High throughput correlation of polymorphic forms with multiple phenotypes within clinical populations |
EP1578399A4 (de) | 2002-12-06 | 2007-11-28 | Isis Pharmaceuticals Inc | Verfahren für die rasche identifikation von pathogenen bei tier und mensch |
ZA200506094B (en) | 2002-12-31 | 2006-11-29 | Mmi Genomics Inc | Compositions, methods and systems for inferring bovine traits |
WO2004064972A2 (en) | 2003-01-16 | 2004-08-05 | Hk Pharmaceuticals, Inc. | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions |
JP4365822B2 (ja) * | 2003-02-27 | 2009-11-18 | 株式会社日立製作所 | 塩基配列関連情報を用いた情報処理システム |
EP1601972A2 (de) * | 2003-03-07 | 2005-12-07 | Sequenom, Inc. | Assoziation polymorpher kinase-ankerproteine mit kardiophänotypen und damit verbundene verfahren |
JP2004287619A (ja) * | 2003-03-19 | 2004-10-14 | Ntt Data Corp | 疫学情報管理装置、疫学情報管理方法、および、プログラム |
DK1660680T3 (da) | 2003-07-31 | 2009-06-22 | Sequenom Inc | Fremgangsmåde til multipleks-polymerasekædereaktioner på höjt niveau og homogene masseforlængelsesreaktioner til genotypebestemmelse af polymorfismer |
WO2005024068A2 (en) | 2003-09-05 | 2005-03-17 | Sequenom, Inc. | Allele-specific sequence variation analysis |
US7608394B2 (en) * | 2004-03-26 | 2009-10-27 | Sequenom, Inc. | Methods and compositions for phenotype identification based on nucleic acid methylation |
EP2395098B1 (de) | 2004-03-26 | 2015-07-15 | Agena Bioscience, Inc. | Basenspezifische Spaltung methylierungsspezifischer Amplifikationsprodukte in Kombination mit Massenanalyse |
US20050266411A1 (en) | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
AU2006272776B2 (en) | 2005-07-21 | 2012-01-19 | Ibis Biosciences, Inc. | Methods for rapid identification and quantitation of nucleic acid variants |
JP2007102709A (ja) * | 2005-10-07 | 2007-04-19 | Toshiba Corp | 遺伝子診断用のマーカー選定プログラム、該プログラムを実行する装置及びシステム、並びに遺伝子診断システム |
US8871471B2 (en) | 2007-02-23 | 2014-10-28 | Ibis Biosciences, Inc. | Methods for rapid forensic DNA analysis |
US20080228699A1 (en) | 2007-03-16 | 2008-09-18 | Expanse Networks, Inc. | Creation of Attribute Combination Databases |
JP5030166B2 (ja) | 2007-05-01 | 2012-09-19 | 独立行政法人産業技術総合研究所 | レーザー脱離イオン化質量分析に使用される試料支持用基板の試験方法 |
JP5036042B2 (ja) * | 2007-05-28 | 2012-09-26 | 株式会社島津製作所 | 質量分析サンプルの調製方法、リボ核酸のイオン化方法、リボ核酸の質量分析方法、及び細胞由来の低分子リボ核酸の質量分析方法 |
US20100112590A1 (en) | 2007-07-23 | 2010-05-06 | The Chinese University Of Hong Kong | Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment |
KR20160113145A (ko) | 2007-07-23 | 2016-09-28 | 더 차이니즈 유니버시티 오브 홍콩 | 핵산 서열 불균형의 결정 |
US20090043752A1 (en) | 2007-08-08 | 2009-02-12 | Expanse Networks, Inc. | Predicting Side Effect Attributes |
US8200509B2 (en) | 2008-09-10 | 2012-06-12 | Expanse Networks, Inc. | Masked data record access |
US7917438B2 (en) | 2008-09-10 | 2011-03-29 | Expanse Networks, Inc. | System for secure mobile healthcare selection |
US8108406B2 (en) | 2008-12-30 | 2012-01-31 | Expanse Networks, Inc. | Pangenetic web user behavior prediction system |
EP3276526A1 (de) | 2008-12-31 | 2018-01-31 | 23Andme, Inc. | Suche nach verwandten in einer datenbank |
DE112010004125A5 (de) * | 2009-10-21 | 2012-11-22 | Basf Plant Science Company Gmbh | Verfahren zur erzeugung von biomarker-referenzpattern |
CN111710361A (zh) * | 2011-11-07 | 2020-09-25 | 凯杰雷德伍德城公司 | 用于识别原因性基因组变体的方法和系统 |
US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
JP6090201B2 (ja) * | 2014-02-19 | 2017-03-08 | 株式会社島津製作所 | マススペクトルデータ処理装置及びマススペクトルデータ処理方法 |
CN106852176A (zh) | 2014-03-25 | 2017-06-13 | 凡弗3基因组有限公司 | 用于功能证实癌症突变的rna分析的系统和方法 |
US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
GB201518391D0 (en) | 2015-10-16 | 2015-12-02 | Micromass Ltd | Processing mass spectral data |
US20220020481A1 (en) | 2020-07-20 | 2022-01-20 | Abbott Laboratories | Digital pass verification systems and methods |
CN114023379B (zh) * | 2021-12-31 | 2022-05-13 | 浙江迪谱诊断技术有限公司 | 一种确定基因型的方法及装置 |
CN114755289A (zh) * | 2022-03-25 | 2022-07-15 | 浙江迪谱诊断技术有限公司 | 一种核酸质谱盐离子干扰评价方法 |
Family Cites Families (44)
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US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
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US9720195B2 (en) | 2010-04-30 | 2017-08-01 | Corning Optical Communications LLC | Apparatuses and related components and methods for attachment and release of fiber optic housings to and from an equipment rack |
-
2000
- 2000-10-13 EP EP09157036.6A patent/EP2088209B1/de not_active Expired - Lifetime
- 2000-10-13 IL IL14893000A patent/IL148930A0/xx unknown
- 2000-10-13 AT AT00972148T patent/ATE444532T1/de not_active IP Right Cessation
- 2000-10-13 DE DE60043076T patent/DE60043076D1/de not_active Expired - Lifetime
- 2000-10-13 AU AU10848/01A patent/AU776811C/en not_active Ceased
- 2000-10-13 CA CA002387035A patent/CA2387035A1/en not_active Abandoned
- 2000-10-13 JP JP2001530799A patent/JP2003519829A/ja active Pending
- 2000-10-13 KR KR1020027004776A patent/KR20020064298A/ko not_active Application Discontinuation
- 2000-10-13 EP EP00972148A patent/EP1261932B1/de not_active Expired - Lifetime
- 2000-10-13 WO PCT/US2000/028413 patent/WO2001027857A2/en active IP Right Grant
-
2003
- 2003-10-21 JP JP2003360454A patent/JP2004158005A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU776811C (en) | 2005-07-28 |
IL148930A0 (en) | 2002-09-12 |
WO2001027857A9 (en) | 2002-12-05 |
JP2003519829A (ja) | 2003-06-24 |
WO2001027857A3 (en) | 2002-10-03 |
AU776811B2 (en) | 2004-09-23 |
JP2004158005A (ja) | 2004-06-03 |
EP2088209B1 (de) | 2017-05-31 |
ATE444532T1 (de) | 2009-10-15 |
WO2001027857A2 (en) | 2001-04-19 |
CA2387035A1 (en) | 2001-04-19 |
EP2088209A1 (de) | 2009-08-12 |
EP1261932B1 (de) | 2009-09-30 |
KR20020064298A (ko) | 2002-08-07 |
AU1084801A (en) | 2001-04-23 |
EP1261932A2 (de) | 2002-12-04 |
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