IL148669A0 - 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof - Google Patents

7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof

Info

Publication number
IL148669A0
IL148669A0 IL14866900A IL14866900A IL148669A0 IL 148669 A0 IL148669 A0 IL 148669A0 IL 14866900 A IL14866900 A IL 14866900A IL 14866900 A IL14866900 A IL 14866900A IL 148669 A0 IL148669 A0 IL 148669A0
Authority
IL
Israel
Prior art keywords
heteroarylthio
acylamino
prodrugs
carboxylic acid
acid antibiotics
Prior art date
Application number
IL14866900A
Other languages
English (en)
Original Assignee
Essential Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Essential Therapeutics Inc filed Critical Essential Therapeutics Inc
Publication of IL148669A0 publication Critical patent/IL148669A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL14866900A 1999-09-22 2000-09-21 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof IL148669A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15549699P 1999-09-22 1999-09-22
PCT/US2000/026069 WO2001021623A1 (fr) 1999-09-22 2000-09-21 Antibiotiques a l'acide 7-acylamino-3-heteroarylthio-3-cephem carboxylique et promedicaments de ces derniers

Publications (1)

Publication Number Publication Date
IL148669A0 true IL148669A0 (en) 2002-09-12

Family

ID=22555673

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14866900A IL148669A0 (en) 1999-09-22 2000-09-21 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof
IL148669A IL148669A (en) 1999-09-22 2002-03-13 7-acylamino-3-heteroarylthio-3- cephem carboxylic acid antibiotics and prodrugs thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL148669A IL148669A (en) 1999-09-22 2002-03-13 7-acylamino-3-heteroarylthio-3- cephem carboxylic acid antibiotics and prodrugs thereof

Country Status (24)

Country Link
EP (1) EP1222194B1 (fr)
JP (1) JP2003509512A (fr)
KR (1) KR20020068508A (fr)
CN (1) CN1206231C (fr)
AR (1) AR029004A1 (fr)
AT (1) ATE297934T1 (fr)
AU (1) AU784077B2 (fr)
BR (1) BR0014230A (fr)
CA (1) CA2385479A1 (fr)
CZ (1) CZ2002993A3 (fr)
DE (1) DE60020862D1 (fr)
HK (1) HK1048121B (fr)
HU (1) HUP0202663A3 (fr)
IL (2) IL148669A0 (fr)
MX (1) MXPA02003024A (fr)
MY (1) MY136038A (fr)
NO (1) NO20021416L (fr)
NZ (1) NZ517761A (fr)
PL (1) PL354919A1 (fr)
RU (1) RU2225868C2 (fr)
SK (1) SK4122002A3 (fr)
TW (1) TWI283682B (fr)
WO (1) WO2001021623A1 (fr)
ZA (1) ZA200202065B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534656B2 (en) 2001-05-31 2003-03-18 North Carolina State University Short synthesis of pyridine-based pharmaceutical intermediates
CA2526875A1 (fr) * 2003-04-30 2004-11-18 Trine Pharmaceuticals, Inc. Beta-lactamine de la classe des carbacephems
CN111187281B (zh) * 2020-02-11 2023-03-14 广西科技大学 含胍基的头孢菌素衍生物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA18891A1 (fr) * 1979-07-05 1981-04-01 Ciba Geigy Ag Composes d'amino-thiadiazolyle,procede pour leur preparation
EP0025017A1 (fr) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Composés polyazathia, procédé pour leur préparation, compositions pharmaceutiques les contenant et utilisation de ces dernières
CA2089728A1 (fr) * 1990-09-13 1992-03-14 James S. Frazee Acides pyridylthio- ou pyridyloxyalcanoiques
WO1995026966A1 (fr) * 1994-04-01 1995-10-12 Microcide Pharmaceuticals, Inc. Cephalosporines antibiotiques
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
WO1996038450A1 (fr) * 1995-05-31 1996-12-05 Microcide Pharmaceuticals, Inc. Cephalosporines
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
JP4174093B2 (ja) * 1998-01-09 2008-10-29 富士フイルムファインケミカルズ株式会社 トリアゾール誘導体ハロゲン化合物の製造方法
NZ507675A (en) * 1998-05-13 2002-11-26 Lg Chemical Ltd Cephalosporin compounds and antimicrobial compositions thereof

Also Published As

Publication number Publication date
KR20020068508A (ko) 2002-08-27
BR0014230A (pt) 2002-05-21
CN1206231C (zh) 2005-06-15
AU7709500A (en) 2001-04-24
NO20021416L (no) 2002-05-22
CZ2002993A3 (cs) 2002-07-17
EP1222194A1 (fr) 2002-07-17
HUP0202663A2 (hu) 2002-12-28
EP1222194B1 (fr) 2005-06-15
HUP0202663A3 (en) 2003-10-28
WO2001021623A1 (fr) 2001-03-29
CN1451011A (zh) 2003-10-22
MY136038A (en) 2008-08-29
CA2385479A1 (fr) 2001-03-29
AU784077B2 (en) 2006-02-02
NO20021416D0 (no) 2002-03-21
ZA200202065B (en) 2007-11-28
HK1048121A1 (en) 2003-03-21
JP2003509512A (ja) 2003-03-11
HK1048121B (zh) 2005-11-04
AR029004A1 (es) 2003-06-04
NZ517761A (en) 2003-10-31
IL148669A (en) 2006-04-10
RU2225868C2 (ru) 2004-03-20
TWI283682B (en) 2007-07-11
MXPA02003024A (es) 2003-09-25
DE60020862D1 (de) 2005-07-21
ATE297934T1 (de) 2005-07-15
PL354919A1 (en) 2004-03-22
SK4122002A3 (en) 2003-03-04

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Legal Events

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